Changing the paradigm: new directions in federal oversight of human research.

abstract：OBJECTIVE:The hypothesis that prenatal stress lowers the levels of protective microflora and increases the risk for postpartum Gram-negative pathogens was tested in infant monkeys. METHODS:Female monkeys were left undisturbed or were stressed during pregnancy using an acoustical startle paradigm for 6 weeks either ear...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bailey MT,Lubach GR,Coe CL

更新日期：2004-04-01 00:00:00

abstract：OBJECTIVES:Parents of children with autism spectrum disorders (ASDs) often report gastrointestinal (GI) dysfunction in their children. The objectives of the present study were to determine whether infants at high risk for developing ASD (ie, siblings of children diagnosed as having ASD) show greater prevalence of GI pr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Penn AH,Carver LJ,Herbert CA,Lai TS,McIntire MJ,Howard JT,Taylor SF,Schmid-Schönbein GW,Dobkins KR

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:Gender equality in the workplace has not been described in pediatric gastroenterology. METHODS:An electronic survey that explored perceptions of career parity, work-life balance, and workplace harassment was sent to all members of the North American Society for Pediatric Gastroenterology, Hepatology, and Nu...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tomer G,Xanthakos S,Kim S,Rao M,Book L,Litman HJ,Fishman LN

更新日期：2015-04-01 00:00:00

abstract：:We evaluated nutritional status, pulmonary impairment, nutritional intake, and fat absorption in 73 cystic fibrosis (CF) patients to identify the primary factor(s) influencing growth. In general, the growth pattern in our patients was satisfactory since 60/73 were not underweight. When caloric intake is greater than o...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Costantini D,Padoan R,Curcio L,Giunta A

更新日期：1988-01-01 00:00:00

abstract：OBJECTIVES:International trends in incidence and outcomes of biliary atresia (BA) are controversial and a wide range of estimates have been reported worldwide. We reviewed the population-based literature to assess international variation of BA incidence and outcomes, and to assess the evidence for seasonal variation in...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Jimenez-Rivera C,Jolin-Dahel KS,Fortinsky KJ,Gozdyra P,Benchimol EI

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:Pediatric Rome III criteria of functional dyspepsia (FD) has eliminated the mandatory use of upper endoscopy and recommended a symptom-based approach. In the absence of alarm symptoms, FD can be positively diagnosed in children having normal physical findings without exclusionary investigations. We aimed to i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tam YH,Chan KW,To KF,Cheung ST,Mou JW,Pang KK,Wong YS,Sihoe JD,Lee KH

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:Although randomized trials demonstrated the efficacy of infliximab for both pediatric Crohn disease and ulcerative colitis (UC), few patients in these studies exhibited colitis requiring hospitalization. The aims of this study were to determine the rate of subsequent infliximab failure and dose escalation in...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Falaiye TO,Mitchell KR,Lu Z,Saville BR,Horst SN,Moulton DE,Schwartz DA,Wilson KT,Rosen MJ

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to characterize the enteral feeding practices in infants after gastrointestinal surgery. METHODS:We performed a retrospective analysis of infants who underwent intestinal surgery at age <6 months who survived to be fed enterally between January 2012 and June 2017. Demographics, surg...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Varma S,Bartlett EL,Nam L,Shores DR

更新日期：2019-02-01 00:00:00

abstract：:The development of alkaline phosphatase, maltase, and sucrase activities in the duodenum of the chick embryo was followed in organ culture in chemically defined medium; 14-day duodenum was used in most experiments, with comparisons being made with 18-day tissue. As has been previously shown for the other enzymes, sucr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Moog F,Goellner JJ

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVES:Polymorphonuclear leukocytes (PMN) feature prominently in the mucosa, including in crypt abscesses, of patients with inflammatory bowel disease, yet the mediators that are responsible for this migration are unknown. We discovered that CXCR2 chemokines (reportedly elevated in the mucosa) have reduced potency ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Stadnyk AW,Carrigan SO,Otley AR

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVES:Hepatocellular carcinoma (HCC) has been linked to chronic viral or metabolic liver disease and other conditions. The characteristics of children with HCC have not been fully elucidated and outcomes in children with predisposing liver disease are not well defined. METHODS:Patients ≤21 years old with HCC mana...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cowell E,Patel K,Heczey A,Finegold M,Venkatramani R,Wu H,López-Terrada D,Miloh T

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Recurrent abdominal pain (RAP) affects up to 34% of the world's population of children. Medical management has been limited, but behavioral strategies have been shown to be effective. In this study several components of published treatment protocols were adapted and/or improved and then compared using a pret...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Humphreys PA,Gevirtz RN

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVE:Assess the impact of zinc supplementation with locally developed culturally specific educational statements (messages) on oral rehydration solution (ORS) and antibiotics or antidiarrheal use in children with acute watery diarrhea as well as to assess adherence and side effects of zinc. METHODS:This was a ran...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Awasthi S,INCLEN Childnet Zinc Effectiveness for Diarrhea (IC-ZED) Group.

更新日期：2006-03-01 00:00:00

abstract：:Membrane distribution in human milk was investigated. Milk samples from six women taken at intervals throughout 9 months of lactation were fractionated into fat globules, skim milk, fluff, and cells. These fractions and the intact milks were analyzed for protein, total lipid, and membrane material as revealed by phosp...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Huston GE,Patton S

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Catheter-related bloodstream infection remains the most common serious complication associated with long-term parenteral nutrition. Taurolock (Bio-Implant HealthCare, Winsen, Germany), which contains taurolidine, is being marketed as a central venous catheter lock solution for decreasing the risk of catheter...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bradshaw JH,Puntis JW

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The Pediatric Ulcerative Colitis Activity Index (PUCAI) is a noninvasive clinician-based index, which reflects disease severity in pediatric ulcerative colitis (UC) when no endoscopy is performed. Here, we aimed to explore signs and symptoms important to children with UC and their caregivers as the first sta...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Marcovitch L,Nissan A,Mack D,Otley A,Hussey S,Mclean B,Lewis M,Croft N,Barakat FM,Griffiths AM,Turner D

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:It is important to identify patients with monogenic IBD as management may differ from classical IBD. In this position statement we formulate recommendations for the use of genomics in evaluating potential monogenic causes of IBD across age groups. METHODS:The consensus included paediatric IBD specialists fr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Uhlig HH,Charbit-Henrion F,Kotlarz D,Shouval DS,Schwerd T,Strisciuglio C,de Ridder L,van Limbergen J,Macchi M,Snapper SB,Ruemmele FM,Wilson DC,Travis SPL,Griffiths AM,Turner D,Klein C,Muise AM,Russell RK,Paediatric IB

更新日期：2020-12-16 00:00:00

abstract：BACKGROUND:There are few studies of Helicobacter pylori reinfection in childhood. In the current study the reinfection rate of H. pylori and ulcer recurrence were investigated during a follow-up period of 12 months or more in children who had undergone eradication therapy. METHODS:Twenty-seven patients aged 5 to 16 ye...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kato S,Abukawa D,Furuyama N,Iinuma K

更新日期：1998-11-01 00:00:00

abstract：:Somatic gene therapy represents a new approach for treating a variety of genetic and acquired diseases and has many potential applications in gastroenterology. Somatic gene therapy is based on the ability to transfer recombinant genes efficiently into somatic tissues, such as the liver or intestine, and achieve expres...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ledley FD

更新日期：1992-04-01 00:00:00

abstract：OBJECTIVES:The present guidelines of the American Academy of Pediatrics recommend that osmolarity not exceed 450 mOsm/kg (or approximately an osmolarity of 400 mOsm/L) for breast milk or infant formulae, to minimize the risk factors for necrotizing enterocolitis. A commercial protein supplement has been developed to me...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kreissl A,Zwiauer V,Repa A,Binder C,Haninger N,Jilma B,Berger A,Haiden N

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Recently, sporadic cases of acute hepatitis and fulminant hepatitis caused by hepatitis E virus (HEV) have been reported in Japan. However, few reports have addressed the issue of HEV infection during childhood. METHODS:This study included 5 patients with fulminant hepatitis, 30 patients with acute hepatiti...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Goto K,Ito K,Sugiura T,Ando T,Mizutani F,Miyake Y,Kawabe Y,Sugiyama K,Togari H

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVE:Data suggest an increase in the incidence of pediatric inflammatory bowel disease (IBD). We examined the trend of the incidence of IBD in children. PATIENTS AND METHODS:A retrospective investigation was conducted on a cohort of children diagnosed with IBD between 1991 and 2002 who were registered in the IBD ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Malaty HM,Fan X,Opekun AR,Thibodeaux C,Ferry GD

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to validate a brief Bowel Habit Questionnaire (BHQ) with prospectively obtained data from a 14-day diary and to determine whether the BHQ predicts the development of medically significant constipation (MSC) during the following year. MATERIALS AND METHODS:The BHQ was distributed to ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Wald ER,Jagodzinski TD,Moyer SC,Wald A,Eickhoff JC,Edmonson MB

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:Discordance exists between outcomes of endoscopy, multichannel intraluminal impedance monitoring (pH-MII), MII baselines, and gastroesophageal reflux symptoms. The aim of the present study was to determine the association between endoscopy, pH-MII and MII baselines, in children with gastroesophageal reflux s...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： van der Pol RJ,Loots CM,Peeters L,Vandenplas Y,Hauser B,Devreker T,Omari TI,Benninga MA,van Wijk MP

更新日期：2013-02-01 00:00:00

abstract：:Milk was collected from eight mothers. Total lipid and free fatty acids were determined on collection. The samples were divided into aliquots and stored at 25, 4, or -11 degrees C for 6, 12, 24, or 48 h. Additional samples were stored at -11 or -70 degrees C for 1, 2, 4, 6, or 8 weeks. The effect of temperature, lengt...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lavine M,Clark RM

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVES:Although several studies report on the experience with adult eosinophilic esophagitis (EoE)-related stricture, outcomes for pediatric patients with EoE-associated fibrostenosis and stricture is more limited. To address this, we aim to identify the adverse event (AE) rate and short-term outcomes of the larges...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Menard-Katcher C,Furuta GT,Kramer RE

更新日期：2017-05-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to assess the adequacy of polyunsaturated fatty acid intake by rural Bangladeshi children 24 to 48 months old in relation to their breast-feeding status. MATERIALS AND METHODS:Multistage sampling was used to select a representative sample of children 24 to 48 months of age from 2 rur...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Yakes EA,Arsenault JE,Islam MM,Ahmed T,German JB,Drake C,Hossain MB,Lewis BL,Rahman AS,Jamil KM,Brown KH

更新日期：2011-03-01 00:00:00

abstract：:Quality training in pediatric gastroenterology, hepatology, and nutrition is essential for the future of our specialty from advancing the science through research to providing clinical care for children with gastrointestinal, hepatic and nutritional disorders. As educational theory has developed, both the American Boa...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sauer CG,Robson J,Turmelle YP,Cerezo CS,Loomes KM,Huang JS,Quiros-Tejeira RE,Benkov KJ,Narkewicz MR,Leichtner A,Weinstein T

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Hirschsprung disease (HSCR) has previously been associated with inflammatory bowel disease (IBD). There are no data to show how common this association is. The aim of the present study was to assess the risk of IBD in individuals with HSCR in a population-based cohort. METHODS:This was a nationwide, populat...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Löf Granström A,Amin L,Arnell H,Wester T

更新日期：2018-03-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to quantify absorption coefficients of specific fatty acids in preterm infants as a function of diet, formula or breast milk (BM), and postnatal age; to identify the fatty acid structural characteristics that determine optimal fatty acid absorption. METHODS:Fatty acids from ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Martin CR,Cheesman A,Brown J,Makda M,Kutner AJ,DaSilva D,Zaman M,Freedman SD

更新日期：2016-01-01 00:00:00