Abstract：
:Membrane distribution in human milk was investigated. Milk samples from six women taken at intervals throughout 9 months of lactation were fractionated into fat globules, skim milk, fluff, and cells. These fractions and the intact milks were analyzed for protein, total lipid, and membrane material as revealed by phospholipid and cholesterol contents. All fractions showed initial levels of membrane that dropped by 1 month and then remained relatively unchanged thereafter. Total lipid (fat globules) in the milks was the primary factor determining membrane content. Distribution of membrane in mature milks was: fat globules, 80%; skim milk, 20% (including fluff, 5%); and cells, less than 1%. Mature milk assures the infants a relatively steady supply of membrane material. However, there appears to be approximately twice as high a concentration of it in milk during the first several weeks of lactation. At that time, the skim milk phase accounts for approximately 30% of milk membrane as compared to 20% during subsequent lactation.
journal_name
J Pediatr Gastroenterol Nutrjournal_title
Journal of pediatric gastroenterology and nutritionauthors
Huston GE,Patton Sdoi
10.1097/00005176-198607000-00017subject
Has Abstractpub_date
1986-07-01 00:00:00pages
602-7issue
4eissn
0277-2116issn
1536-4801journal_volume
5pub_type
杂志文章abstract：OBJECTIVES:Discordance exists between outcomes of endoscopy, multichannel intraluminal impedance monitoring (pH-MII), MII baselines, and gastroesophageal reflux symptoms. The aim of the present study was to determine the association between endoscopy, pH-MII and MII baselines, in children with gastroesophageal reflux s...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0b013e31827167e2
更新日期：2013-02-01 00:00:00
abstract：:An infant boy with severe portal hypertension developed failure to thrive and malabsorption. Clinical findings and ultrasonography suggested the presence of an arteriovenous shunt, and hepatic angiography confirmed the diagnosis and outlined the anatomy of the vascular malformation, which was an intrahepatic arteriopo...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198705000-00027
更新日期：1987-05-01 00:00:00
abstract：OBJECTIVES:Intestinal failure-associated liver disease (IFALD) contributes to significant morbidity in pediatric patients with intestinal failure (IF); however, the use of parenteral nutrition (PN) with a fish oil-based intravenous (IV) emulsion (FO) has been associated with biochemical reversal of cholestasis and impr...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000000609
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to determine whether an oral treatment with a commercial pharmaceutical product containing Saccharomyces boulardii would reduce the duration of diarrhea in infants with acute diarrhea. PATIENTS AND METHODS:In the present double-blind, placebo-controlled study, 186 infants, 6 to 48 mo...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章,随机对照试验
doi：10.1097/MPG.0b013e31822b7ab0
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVE:Our previous studies suggested that human milk proteases begin to hydrolyze proteins in the mammary gland and continue within the term infant' stomach. No research has measured milk protease and pepsin activity in the gastric aspirates of preterm infants after human milk feeding. This study investigated how t...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000001719
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND AND AIM:Distinguishing biliary atresia (BA) from other causes of neonatal cholestasis (NC) is challenging. Continuous BreathID C-methacetin breath test (MBT) is a novel method that determines liver function. Methacetin is metabolized uniquely by the liver and CO2 is measured passively, through a nasal cannul...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 临床试验,杂志文章
doi：10.1097/MPG.0b013e3182638d29
更新日期：2013-01-01 00:00:00
abstract：:We evaluated the diagnostic delay (time from first symptoms to diagnosis) in 100 pediatric patients with Crohn disease (CD) and 75 patients with ulcerative colitis (UC). Median (interquartile range) diagnostic delay in patients with CD was 4 (2-8) (range 0-82) months compared with 2 (1-7) (range 0-52) months in patien...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000001238
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to describe the clinical experience with the anti-tumor necrosis factor chimeric monoclonal antibody, infliximab, in pediatric patients with Crohn disease in The Netherlands. DESIGN:Descriptive. METHODS:Clinical response and adverse effects of infliximab were recorded for pedia...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-200407000-00010
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVE:Antiendomysial antibody (EMA) production has been induced in vitro by the small bowel mucosa of celiac disease (CD) patients in clinical remission cultured in the presence of gliadin peptides. The aim of the present study was to use this in vitro system to determine whether it could be used to predict the cli...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00005176-200502000-00015
更新日期：2005-02-01 00:00:00
abstract：OBJECTIVES:Functional dyspepsia (FD) is a functional abdominal pain disorder. There is paucity of data on the economic impact of FD in children. Primary aim of our study was to estimate annual evaluation cost ("diagnosis and visit" cost) and secondary aim was to identify potential prognostic factors of FD in children. ...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000002599
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:Liver transplantation is established treatment for children with end-stage liver disease and has a 5-year survival rate of 80% to 85%, even in infants under 12 months. Long-term outcome in nutritional rehabilitation and normal development is unknown. This study aimed to prospectively evaluate growth and psyc...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-200003000-00011
更新日期：2000-03-01 00:00:00
abstract：:The apolipoprotein (apo) A-I:B ratio and the apo B concentration were determined by radial immunodiffusion in dried blood spot samples from 1,767 10- and 11-year-old children. Children with either apo A-I:B ratios below the first percentile or apo B levels above the 99th were recalled and plasma lipid and apolipoprote...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：
更新日期：1990-02-01 00:00:00
abstract：:The widely held belief that 50% of the iron in human milk is absorbed is based on studies that have used an extrinsic radioactive iron tag. To determine the validity of an extrinsic tag, it is necessary to label the milk intrinsically with one isotope and to compare absorption of this isotope with absorption of anothe...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198911000-00022
更新日期：1989-11-01 00:00:00
abstract：INTRODUCTION:For a large portion of youth, pain-associated functional gastrointestinal disorders (FGIDs) are associated with significant impairment over time. Clinically feasible methods to categorize youth with FGIDs at greatest risk for persistent pain-related impairment have not yet been identified. METHODS:Measure...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 临床试验,杂志文章
doi：10.1097/MPG.0000000000001342
更新日期：2017-05-01 00:00:00
abstract：OBJECTIVES:Intestinal epithelial restitution is the first part in the process of mucosal repair after injury in the intestine. Integrity of the intestinal mucosal barrier is important as a first line of defense against bacteria and endotoxin. Necrotizing enterocolitis (NEC) is a major cause of morbidity and mortality i...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0b013e31823a895a
更新日期：2012-05-01 00:00:00
abstract：:Four hundred ninety-eight acetylcholinesterase-stained suction rectal biopsies from 456 children were examined to assess the occurrence of "isolated" or "primary" intestinal neuronal dysplasia at Children's Hospital of Pittsburgh. Cases of proven Hirschsprung's disease were excluded. In 38 biopsies from 38 patients, w...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-199102000-00008
更新日期：1991-02-01 00:00:00
abstract：:Young infants with cystic fibrosis (CF) are at risk for developing symptomatic protein-calorie malnutrition (PCM) characterized by hypoalbuminemia, edema, and anemia. We reviewed the hospital charts of all infants less than 12 months of age referred to our CF clinic between 1979 and 1982 and found nine patients with P...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198605000-00010
更新日期：1986-05-01 00:00:00
abstract：BACKGROUND:Findings in studies in rodents have suggested that epithelial growth of the small intestine is dependent on activation of the immune system. The purpose of this study was to compare changes of postnatal epithelial growth with immunologic activity in humans. METHODS:Duodenal biopsies were obtained by endosco...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-199805000-00004
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:Standardized outcome measures provide a basis for comparing outcomes of different clinical trials. Consequently, they can serve as the foundation for determining which therapeutic interventions are most effective. The aim of the present study is to systematically assess how definitions and outcome measures ar...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章,评审
doi：10.1097/MPG.0000000000001110
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:The development of de novo autoimmune hepatitis as a long-term complication after liver transplantation has been recently reported. The authors describe five liver allograft recipients who developed chronic hepatitis associated with autoimmune features. METHODS:Five of 155 liver transplant recipients at ris...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-200102000-00007
更新日期：2001-02-01 00:00:00
abstract：BACKGROUND:In clinical and field conditions, breath gas analysis has been widely used in evaluating carbohydrate digestion. A field study was performed to determine the prevalence of lactose malabsorption in Myanmar children and to evaluate the possibility of using breath methane excretion to indicate lactose malabsorp...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-199905000-00006
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVES:Midgut volvulus with malrotation is typical in newborns. We present our experience to emphasize the importance of suspecting midgut volvulus as a cause of abdominal pain also beyond infancy, particularly in relation to malrotation, and the relevance of ultrasonographic (US) signs in its diagnosis. METHODS:A...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000000505
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVES:The aim of this systematic review and meta-analysis was to assess immune response to vaccination in children and young people with inflammatory bowel disease (IBD). In patients with IBDs, both the disease itself and its treatment can affect the vaccine response. METHODS:Medical databases were searched for r...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000002810
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVES:Adult-based guidelines support the use of the pull (extraction) endoscopic technique in managing esophageal food bolus impactions (FBIs) but allow the consideration of the push (advancement) technique with caution based on available published literature. The North American Society for Pediatric Gastroenterol...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000001639
更新日期：2018-01-01 00:00:00
abstract：:Vitamin K prophylaxis is recommended to prevent the hazard of hemorrhage caused by vitamin K deficiency in young infants. A single administration after birth seems inadequate to completely prevent late haemorrhagic disease in breast-fed infants. The preventive effect of a daily oral dose of 25 micrograms vitamin K1, w...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-199304000-00014
更新日期：1993-04-01 00:00:00
abstract：:Acarboxy prothrombin was detected in the plasma of 48 of 128 umbilical cord plasma samples and in all of 65 patients receiving coumadin. None was found in 20 normal adults. Although the prevalence was the same in blacks, whites, and neonates of mixed origin, levels were significantly higher in blacks. There was a nega...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/00005176-198406000-00025
更新日期：1984-06-01 00:00:00
abstract：OBJECTIVES:The aim of the present review was to provide recommendations on the use of hydrolysates in infants when formula feeding is initiated. METHODS:We performed an overview of reviews followed by a systematic review of subsequently published trials. RESULTS:We found 8 systematic reviews; only 1 study of limited ...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章,评审
doi：10.1097/MPG.0000000000000318
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVES:Microvillous inclusion disease (MVID) is a cause of intractable diarrhea in infancy. In its classic form, the disease is characterized by a severe persistent watery diarrhea starting within the first days of life. Parenteral nutrition and small bowel transplantation are the only known treatments for the affe...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000000526
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVES:Inflammatory bowel disease (IBD) is a chronic lifelong condition and is related to poor quality of life (QoL). The aim of this study was to evaluate the QoL of Asian pediatric patients with IBD and to determine the clinical factors that can influence QoL. METHODS:Children and adolescents aged 9 to 18 years ...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章,多中心研究
doi：10.1097/MPG.0000000000002119
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVES:Impaired growth has been reported in children born with esophageal atresia (EA). Their nutritional fate at adulthood remains uncertain though. Our objectives were to determine the body mass index (BMI) of adult patients with EA followed up from 2009 to 2011 in the EA clinic of a university-affiliated hospita...
journal_title：Journal of pediatric gastroenterology and nutrition
pub_type： 杂志文章
doi：10.1097/MPG.0000000000000961
更新日期：2016-03-01 00:00:00
