Changes in Proteases, Antiproteases, and Bioactive Proteins From Mother's Breast Milk to the Premature Infant Stomach.

abstract：:The plasma endotoxin levels of 16 severely malnourished Thai children were determined by the Limulus amebocyte lysate assay. Endotoxemia was present in seven children (44%) on admission to the hospital and was associated with the coexistence of vitamin A deficiency. Protein-energy malnutrition is associated with the p...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Klein K,Fuchs GJ,Kulapongs P,Mertz G,Suskind RM,Olson RE

更新日期：1988-03-01 00:00:00

abstract：:To evaluate the role of food-specific antibody response to soy protein and its fractions in patients with soy protein intolerance, allergen-specific IgG and IgE to these proteins were measured by enzyme-linked immunosorbent assays (ELISAS) and immunoblotting. A crude soy extract and the 7S, 11S, and whey fractions wer...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Burks AW,Casteel HB,Fiedorek SC,Williams LW,Connaughton C,Brooks JR

更新日期：1989-02-01 00:00:00

abstract：OBJECTIVES:In developed countries, small bowel histology in coeliac disease is a spectrum, ranging from normal with increased intraepithelial lymphocytes to the classic flat mucosa. In developing countries, mild to moderate enteropathies in children with chronic diarrhea and growth failure are assumed to be caused by t...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bhatnagar S,Gupta SD,Mathur M,Phillips AD,Kumar R,Knutton S,Unsworth DJ,Lock RJ,Natchu UC,Mukhopadhyaya S,Saini S,Bhan MK

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the tolerability, safety, and efficacy of polyethylene glycol (PEG) 3350 without electrolytes as a 1-day bowel preparation for colonoscopy in children. METHODS:A prospective study of 45 children undergoing colonoscopy prescribed PEG 3350 without electrolytes mixed with a ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Walia R,Steffen R,Feinberg L,Worley S,Mahajan L

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:To determine the natural history of treated and untreated eosinophilic esophagitis (EE) and examine the presenting symptoms of EE. PATIENTS AND METHODS:Retrospective and prospective chart review of all patients diagnosed with EE at The Children's Hospital of Philadelphia. EE was defined as greater than 20 eo...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Spergel JM,Brown-Whitehorn TF,Beausoleil JL,Franciosi J,Shuker M,Verma R,Liacouras CA

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVES:The aim of this review was to examine the characteristics of the faecal calprotectin assay in neonates and the evidence for its use as a noninvasive marker of intestinal illnesses during the neonatal period. METHODS:Bibliographic searches were performed in the MEDLINE electronic database up to February 2010...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kapel N,Campeotto F,Kalach N,Baldassare M,Butel MJ,Dupont C

更新日期：2010-11-01 00:00:00

abstract：:Few advances would contribute more to the growth and well-being of infants and children in the developing world than the making available of acceptable staple foods that are easy to grow and process, nutritionally complete enough to serve as the major weaning food, and safe without refrigeration. High-fat quality-prot...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Graham GG

更新日期：1993-08-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to understand the association between parents' perceptions of the decision process and the decision outcomes in decisions about the use of biologics in pediatric chronic conditions. METHODS:We mailed surveys to parents of children with inflammatory bowel disease or juvenile idiopath...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lipstein EA,Lovell DJ,Denson LA,Kim SC,Spencer C,Ittenbach RF,Britto MT

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:Inflammatory bowel disease (IBD) is a chronic lifelong condition and is related to poor quality of life (QoL). The aim of this study was to evaluate the QoL of Asian pediatric patients with IBD and to determine the clinical factors that can influence QoL. METHODS:Children and adolescents aged 9 to 18 years ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kim S,Park S,Kang Y,Kim JE,Kang B,Choe BH,Lee YJ,Park JH,Yang HR,Lee SH,Kim KM,Ryoo E,Tchah H,Shim JO,Koh H

更新日期：2019-01-01 00:00:00

abstract：:We performed a Japanese nationwide survey of pediatric-onset chronic nonspecific multiple ulcers of the small intestine between January 2000 and July 2013 in 176 institutions of pediatric surgery or pediatric gastroenterology and clarified the clinical features associated with genetic abnormalities in the Solute Carri...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Uchida K,Nakajima A,Ushijima K,Ida S,Seki Y,Kakuta F,Abukawa D,Tsukahara H,Maisawa SI,Inoue M,Araki T,Umeno J,Matsumoto T,Taguchi T

更新日期：2017-04-01 00:00:00

abstract：:An infant boy with severe portal hypertension developed failure to thrive and malabsorption. Clinical findings and ultrasonography suggested the presence of an arteriovenous shunt, and hepatic angiography confirmed the diagnosis and outlined the anatomy of the vascular malformation, which was an intrahepatic arteriopo...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Iñon AE,D'Agostino D

更新日期：1987-05-01 00:00:00

abstract：OBJECTIVES:Infectious diarrhea, a leading cause of morbidity and deaths, is less prevalent in breastfed infants compared with infants fed infant formula. The dominant human milk oligosaccharide (HMO), α-1,2-fucosyllactose (2'-FL), has structural homology to bacterial adhesion sites in the intestine and may in part expl...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cilieborg MS,Sangild PT,Jensen ML,Østergaard MV,Christensen L,Rasmussen SO,Mørbak AL,Jørgensen CB,Bering SB

更新日期：2017-02-01 00:00:00

abstract：:The effect of oral epidermal growth factor (EGF) on histological and biochemical changes in epithelium in the small intestine was studied in colostrum-deprived neonatal pigs. Forty-eight pigs were infected at 4 days of age with 2 x 10(7) plaque-forming units of porcine group A rotavirus and orally fed a simulated sow-...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Zijlstra RT,Odle J,Hall WF,Petschow BW,Gelberg HB,Litov RE

更新日期：1994-11-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to establish an apparent diffusion coefficient (ADC) cut-off value to classify active and non-active lesions in inflammatory bowel disease. METHODS:We reviewed 167 paediatric magnetic resonance enterographies executed for suspected inflammatory bowel disease by using a 1.5- and 3-T s...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Scionti A,Di Maurizio M,Basile M,Bernardini A,Miccoli M,Lionetti P,Defilippi C,Caramella D

更新日期：2019-03-01 00:00:00

abstract：:In progressive familial intrahepatic cholestasis type 2 (PFIC-2), severe steatorrhea is often documented. However, pancreatic exocrine secretion has not yet been studied. In 14 children with PFIC-2, pancreatic function was assessed using standard fecal tests. Normal fecal lipase concentrations excluded isolated lipase...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Walkowiak J,Jankowska I,Pawlowska J,Strautnieks S,Bull L,Thompson R,Herzig KH,Socha J

更新日期：2006-04-01 00:00:00

abstract：:We describe a child born to unrelated parents who developed severe protracted secretory type diarrhea associated with subtotal villus atrophy and intestinal inflammation at the age of 19 months. No infectious, metabolic, or anatomical basis for this condition was identified and the child required total parenteral nutr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Coulthard M,Searle J,Patrick M,Ravenscroft P,Cleghorn G,Shepherd R

更新日期：1990-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to validate a brief Bowel Habit Questionnaire (BHQ) with prospectively obtained data from a 14-day diary and to determine whether the BHQ predicts the development of medically significant constipation (MSC) during the following year. MATERIALS AND METHODS:The BHQ was distributed to ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Wald ER,Jagodzinski TD,Moyer SC,Wald A,Eickhoff JC,Edmonson MB

更新日期：2011-11-01 00:00:00

abstract：OBJECTIVES:Both breast-feeding duration and age at gluten introduction have been implicated in the pathogenesis of celiac disease (CD). We hypothesized that parental CD affects the feeding pattern of the offspring, mediated by parental health awareness increasing adherence to infant feeding guidelines. METHODS:Prospec...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Welander A,Montgomery S,Ludvigsson J,Ludvigsson JF

更新日期：2014-07-01 00:00:00

abstract：:Serum immunoglobulin (Ig) A and IgG gliadin antibodies were determined with a simple, rapid, and inexpensive method--diffusion-in-gel enzyme-linked immunosorbent assay (DIG-ELISA)--and the results were related to small intestinal mucosal morphology in 234 children suspected of having malabsorption. Fifty-six of 58 chi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lindberg T,Nilsson LA,Borulf S,Cavell B,Fällström SP,Jansson U,Stenhammar L,Stintzing G

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to describe the prevalence of childhood constipation, stool characteristics, and their relationship with toilet training and age of introduction of cow's milk. METHODS:A total of 4231 children born in 2004, from a birth cohort study, were assessed at 12, 24, and 48 months of...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mota DM,Barros AJ,Santos I,Matijasevich A

更新日期：2012-10-01 00:00:00

abstract：:Eighty-eight consecutive children with inflammatory bowel disease were studied, and upper gastrointestinal endoscopy was performed in 80 of them as one of the initial investigations before commencing medical or nutritional treatment. Forty-one children were found to have Crohn's disease and 47, ulcerative colitis. Upp...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ruuska T,Vaajalahti P,Arajärvi P,Mäki M

更新日期：1994-08-01 00:00:00

abstract：BACKGROUND:The learning curve in paediatric oesophagogastroduodenoscopy (OGD) is unknown. Using ≥95% D2 (second part of the duodenum) intubation rates as a marker of technical competency, we conducted learning curve analyses to identify when trainees achieve competency in paediatric OGD. Factors associated with compete...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Barraclough H,Siau K,Ward ST,Dunckley P,Hawkes N,Thomson M,Narula P

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:P-glycoprotein (P-gp), the functional product of the multidrug resistance gene (MDR), is a transmembrane protein that extrudes substrates from the intracellular environment. P-gp is expressed on the apical surface of epithelial cells and on cells from the hematopoietic lineage. Human MDR polymorphisms have be...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Staley EM,Dimmitt RA,Schoeb TR,Tanner SM,Lorenz RG

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:For the pediatric population, upper reference limits (URLs) for aminotransferase levels have not been established. The prevalence of high aminotransferase levels provides important information regarding the burden of liver disease in the current childhood obesity endemic. METHODS:We set the URL of alanine a...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Park SH,Park HY,Kang JW,Park J,Shin KJ

更新日期：2012-12-01 00:00:00

abstract：:Major events in gastrointestinal ontogeny occur in the infant rat in association with weaning, resulting in striking alterations in small intestinal structure and function. Although the dietary changes attendant to weaning are not essential for the initiation of these events, dietary nutrients have been shown to parti...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Castillo RO,Feng JJ,Stevenson DK,Kerner JA,Kwong LK

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:Zinc is important for metabolism, cell growth, immunity, and defense against oxygen radicals. Extremely low-birth-weight (< 1000 g) infants have higher nutritional needs, but information on zinc is scarce. The authors performed nutritional balances in 10 infants with birth weights of 500 to 999 g and who wer...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Loui A,Raab A,Obladen M,Brätter P

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:There are limited data on health-related quality of life (HRQOL) in pediatric patients with long-standing pancreatitis (including acute relapsing and chronic pancreatitis) using age-appropriate measurement instruments. METHODS:We evaluated HRQOL in children with long-standing pancreatitis using the PedsQL 4...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Pohl JF,Limbers CA,Kay M,Harman A,Rollins M,Varni JW

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine the in vitro effect(s) of a bovine-based human breast milk fortifier (HMF) on human intestinal cells. HMF increases the expression of BCL2/adenovirus E1B 19 kDa protein-interacting protein (Bnip3) and cell death; the prostaglandin analogue misoprostol will rescue...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Diehl-Jones W,Archibald A,Gordon JW,Mughal W,Hossain Z,Friel JK

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVES:The most common cause of encopresis in children is functional fecal retention (FFR). An international working team suggested that FFR be defined by the following criteria: a history of >12 weeks of passage of <2 large-diameter bowel movements (BMs) per week, retentive posturing, and accompanying symptoms, su...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Loening-Baucke V

更新日期：2004-01-01 00:00:00

abstract：:Pseudomembranous colitis secondary to C. difficile and its toxin(s) is a well-recognized disease in children and usually responds to treatment with oral vancomycin. There are well-documented reports of relapse in adults after initial successful treatment with vancomycin. This report documents relapse in a child who de...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Holmes R,Byrne WJ

更新日期：1986-03-01 00:00:00