Continuous 13C-methacetin breath test differentiates biliary atresia from other causes of neonatal cholestasis.

abstract：OBJECTIVES:The epidemiology and clinical significance of disaccharidase deficiencies have not been thoroughly characterized. Recent work suggests at least genetic sucrase-isomaltase deficiency is more prevalent than previously believed. Because lactase deficiency (LD) is well described, the present study focuses on the...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Cohen SA,Oloyede H,Gold BD,Mohammed A,Elser HE

更新日期：2018-06-01 00:00:00

abstract：:Alkaline phosphatase (AP) activity is an accepted marker of epithelial cell differentiation and integrity in intestinal mucosal explant systems. In experiments involving AP it is usually expressed as activity per unit protein in tissue culture. It has been previously demonstrated that during organ culture a considerab...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Ashkenazi A,Idar D,Maimon M,Hegesh E,Frank E,Hahn T,Wolman Y,Levin S

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Although infection with Helicobacter pylori in children mostly induces asymptomatic chronic gastritis, the clinical outcome of H pylori infection is generally unpredictable. To identify the risk subgroup of infected children who can progress toward serious gastrointestinal disease, we assessed the prevalence...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Homan M,Luzar B,Kocjan BJ,Orel R,Mocilnik T,Shrestha M,Kveder M,Poljak M

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Catheter-related bloodstream infection remains the most common serious complication associated with long-term parenteral nutrition. Taurolock (Bio-Implant HealthCare, Winsen, Germany), which contains taurolidine, is being marketed as a central venous catheter lock solution for decreasing the risk of catheter...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bradshaw JH,Puntis JW

更新日期：2008-08-01 00:00:00

abstract：:In cholestatic diseases, the absorption of fat-soluble compounds, including vitamin K1(20), is low and periodic administration of vitamin K1(20) is often necessary. Due to the low absorption of vitamin K1(20) from the Konakion formulation, late hemorrhagic disease of the newborn also occurs especially after oral vitam...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Amédée-Manesme O,Lambert WE,Alagille D,De Leenheer AP

更新日期：1992-02-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to examine the expression of FOXP3, interleukin (IL)-10, transforming growth factor (TGF)-β1, IL-17A, and T helper 17 (TH17) cells/FOXP3+ regulatory T (Treg) cells balance in the gastric mucosa of children with Helicobacter pylori infection, in relation to the gastric histopat...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Gil JH,Seo JW,Cho MS,Ahn JH,Sung HY

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to estimate the frequency of ABCB4 mutations among children with chronic intrahepatic cholestasis with elevated gamma-glutamyl-transpeptidase (γ-GT) activity and to characterize the genotypes with respect to severity of symptoms, response to ursodeoxycholic acid therapy, and outcome....

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Colombo C,Vajro P,Degiorgio D,Coviello DA,Costantino L,Tornillo L,Motta V,Consonni D,Maggiore G,SIGENP Study Group for Genetic Cholestasis.

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVE:To evaluate esophageal body motor contractions occurring during esophageal reflux in pediatric patients with gastro-esophageal reflux disease (GERD). METHODS:Patients referred for the evaluation of GERD who were evaluated with combined 24-hour pH probe and esophageal manometry test (MP24) were included. Pati...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Chitkara DK,Fortunato C,Nurko S

更新日期：2005-01-01 00:00:00

abstract：:BE is a disorder that occurs in children likely as a consequence of prolonged GE reflux of gastroduodenal contents. It usually presents with complications of GE reflux, but it also may be relatively silent in childhood and then present with adenocarcinoma in childhood or present in adulthood. Although seldom recognize...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hassall E

更新日期：1993-05-01 00:00:00

abstract：:Eighteen children and adolescents, of a total of 90 treated in our unit between 1982 and 1992, underwent colectomy for ulceractive colitis. Six (6.7%) of the 90 patients had short stature, i.e., a height below the 3rd centile, and 8 of the 18 who had surgery had a subnormal height velocity, i.e., below the 25th centil...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Nicholls S,Vieira MC,Majrowski WH,Shand WS,Savage MO,Walker-Smith JA

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVES:Gender equality in the workplace has not been described in pediatric gastroenterology. METHODS:An electronic survey that explored perceptions of career parity, work-life balance, and workplace harassment was sent to all members of the North American Society for Pediatric Gastroenterology, Hepatology, and Nu...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Tomer G,Xanthakos S,Kim S,Rao M,Book L,Litman HJ,Fishman LN

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Many patients with chronic hepatitis C do not respond to antiviral treatment. In adult patients the re-treatment of these patients has been extensively investigated. Because the response to re-treatment in children is not well defined we evaluated the efficacy and safety of interferon (IFN)-alpha plus ribavi...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Gerner P,Hilbich J,Wenzl TG,Behrens R,Walther F,Kliemann G,Enninger A,Wirth S

更新日期：2010-08-01 00:00:00

abstract：OBJECTIVES:Longitudinal intestinal lengthening and tailoring (LILT) is a well-established surgical treatment for short bowel syndrome. It has been shown to enhance peristalsis, decrease bacterial overgrowth, and extend mucosal contact time for nutrients. We present the results of a long-term follow-up of patients who u...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Reinshagen K,Kabs C,Wirth H,Hable N,Brade J,Zahn K,Hagl C,Jester I,Waag KL

更新日期：2008-11-01 00:00:00

abstract：:We have shown that, in the fetal sheep, abolition of fluid ingestion early in gestation results in a profound gastrointestinal tract (GIT)-specific growth retardation and that these effects can be reversed if fetal swallowing is restored, even for relatively short periods (15 days). The fetal esophagus was ligated at ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Trahair JF,Harding R

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the efficacy and safety of propofol and meperidine plus midazolam for sedation during esophagogastroduodenoscopy (EGD) in children. METHODS:Data were collected prospectively and retrospectively from neurologically intact children (0.2-17.7 years of age) who underwent ambulatory diagnostic EGD dur...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Khoshoo V,Thoppil D,Landry L,Brown S,Ross G

更新日期：2003-08-01 00:00:00

abstract：:We evaluated plasma PIVKA-II (protein induced by vitamin K absence or antagonist-II, acarboxy prothrombin) levels in three infants with hepatoblastoma as a tumor marker. PIVKA-II levels were highly elevated in all three patients. Vitamin K administration, performed in two patients, resulted in only moderate reduction ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Motohara K,Endo F,Matsuda I,Iwamasa T

更新日期：1987-01-01 00:00:00

abstract：:The clinical efficacy of twice-daily cimetidine (20 mg/kg/day) was retrospectively studied in 19 children with gastric ulcer (GU) and 23 with duodenal ulcer (DU) in the active stage. Endoscopically confirmed cumulative healing rates at 2, 4, and 8 weeks of treatment were 53.5, 73.7, and 94.7% in the GU group and 15.4,...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kato S,Ozawa A,Shibuya H,Ohtake M,Nakagawa H

更新日期：1994-04-01 00:00:00

abstract：OBJECTIVE:Appetite manipulation can be effective in weaning children off gastrostomy tube feeding dependence but can cause dehydration, hypoglycaemia, and ketone body production, which is anorexigenic. As the safety of this approach has not been described, our aim was to describe adverse events observed when weaning ch...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Pollow AS,Karls CA,Witzlib M,Noel RJ,Goday PS,Silverman AH

更新日期：2018-05-01 00:00:00

abstract：:Enzymatic in vitro hydrolysis was evaluated as a possible treatment to abolish the allergenicity of whey proteins in view of their use in infant formulas. Guinea pigs without prior immunological contact (including fetal life) with cow's milk were fed various preparations of cow's milk proteins. Oral exposure to milk o...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Pahud JJ,Monti JC,Jost R

更新日期：1985-06-01 00:00:00

abstract：OBJECTIVES:The prevalence of ulcerative colitis (UC) differs by country, which is likely due to differences in genetic factors among ethnicities. Moreover, the prevalence of pediatric UC with a family history (FH) is 4.1% in Japanese patients; its clinical course begins at an early age and is more severe. Recently, a g...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fujii T,Sato M,Hosoi K,Ohbayashi N,Ikuse T,Jimbo K,Aoyagi Y,Kudo T,Ohtsuka Y,Shimizu T

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVE:Diarrhea is frequently observed among critically ill children (CIC) admitted for intensive care. There is increasing evidence that probiotics decrease the incidence of acute infectious and nosocomial and antibiotic induced diarrhea amongst children hospitalized in nonintensive care settings. Despite theoretic...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Srinivasan R,Meyer R,Padmanabhan R,Britto J

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:The newborn colon is devoid of microflora, in that bacterial colonization is established after birth. Short chain fatty acids, products of bacterial fermentation, are the major energy source for colonocytes. Because it is not known whether colonocytes in the newborn can metabolize butyrate, this was examined...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Krishnan S,Ramakrishna BS

更新日期：1998-04-01 00:00:00

abstract：:Cyclic vomiting syndrome (CVS) is a disorder noted for its unique intensity of vomiting, repeated emergency department visits and hospitalizations, and reduced quality of life. It is often misdiagnosed due to the unappreciated pattern of recurrence and lack of confirmatory testing. Because no accepted approach to mana...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Li BU,Lefevre F,Chelimsky GG,Boles RG,Nelson SP,Lewis DW,Linder SL,Issenman RM,Rudolph CD,North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition.

更新日期：2008-09-01 00:00:00

abstract：:This study was designed to establish whether the starting time of breast-feeding (BF) may have affected gut closure for macromolecules during the earliest postnatal period. An increase of serum IgA concentrations was taken as the index of gut permeability to macromolecules. In 14 neonates, BF started 1-6 h after birth...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Vukavić T

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Gastric lipase has an important compensatory function in neonatal fat digestion. The activity level of pepsin and its role in protein digestion is less well understood. We have, therefore, studied the ontogeny of lipase and pepsin in the ferret, a species with a neonatal fat digestion pattern similar to that...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hamosh M,Henderson TR,Hamosh P

更新日期：1998-02-01 00:00:00

abstract：:The effect of a lipid emulsion containing long-chain triglycerides (LCT) and supplemented with L-carnitine on plasma lipids and bilirubin in premature neonates on total parenteral nutrition was compared to that of lipid emulsions containing either LCT or a mixture of LCT and medium-chain triglycerides (MCT). In a doub...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Rubin M,Naor N,Sirota L,Moser A,Pakula R,Harell D,Sulkes J,Davidson S,Lichtenberg D

更新日期：1995-07-01 00:00:00

abstract：OBJECTIVE:This position paper written by the Hepatitis Expert Team of the Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition aimed to systematically evaluate clinical practice guidelines (CPGs), medical consensus, and position papers on the use of direct-acting antivirals (DA...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Indolfi G,Fischler B,Gonzalez-Peralta RP,Ciocca M,Porta G,Neelam M,El-Guindi M,Kelly D,Ni YH,Sibal A,Leung DH,Chang MH,Hepatitis Expert Team of the Federation of International Societies of Pediatric Gastroenterology, Hepatology,

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVE:Tumor necrosis factor (TNF)-alpha plays a role in the inflammatory process in Crohn disease, a disease with an apparent polygenic basis. We investigated whether polymorphisms in multiple genes involved in the lipopolysaccharide-TNF inflammatory pathway are independently associated with Crohn disease in the Je...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Silbermintz A,Levine J,Weinstein T,Silver J

更新日期：2008-05-01 00:00:00

abstract：:Current research is directed toward innovative dietary compositions that exert specific effects on health promotion and reducing the risk of diseases. For example, the demonstration that the gut microbiota is an important constituent in the intestine's mucosal barrier has led to new therapeutic strategies for infectio...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Isolauri E

更新日期：2007-12-01 00:00:00

abstract：:We evaluated fecal clearance of alpha 1-antitrypsin (alpha 1-AT) as a method of detecting and quantitating intestinal protein loss in patients with inflammatory bowel disease. We investigated alpha 1-AT clearance (C alpha 1-AT) in 14 patients (seven with Crohn's disease, seven with ulcerative colitis) and in 10 childr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Grill BB,Hillemeier AC,Gryboski JD

更新日期：1984-01-01 00:00:00