Rising incidence of inflammatory bowel disease among children: a 12-year study.

abstract：OBJECTIVES:The aim of the study was to estimate the frequency of ABCB4 mutations among children with chronic intrahepatic cholestasis with elevated gamma-glutamyl-transpeptidase (γ-GT) activity and to characterize the genotypes with respect to severity of symptoms, response to ursodeoxycholic acid therapy, and outcome....

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Colombo C,Vajro P,Degiorgio D,Coviello DA,Costantino L,Tornillo L,Motta V,Consonni D,Maggiore G,SIGENP Study Group for Genetic Cholestasis.

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:Current pediatric guidelines allow noninvasive diagnosis of celiac disease in selected children. We investigated in a large cohort study whether the severity of villous atrophy at diagnosis is associated with clinical characteristics or long-term health outcomes, thus having a prognostic significance. METHO...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kröger S,Kurppa K,Repo M,Huhtala H,Kaukinen K,Lindfors K,Arvola T,Kivelä L

更新日期：2020-07-01 00:00:00

abstract：:The synthetic opiate loperamide (LPMD) is an antidiarrheal compound which affects both intestinal motility and the transport of water and electrolytes. We have investigated its effects on ion transport in the stripped ileal mucosa of rabbits, mounted in Ussing chambers in vitro. Addition of LPMD to serosal bathing med...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Guandalini S,Fasano A,Rao MC,Ferola A,Migliavacca M,Marchesano G,Rubino A

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Results of in vitro studies have documented colonic absorption of lactose in the newborn. A stable isotope model was developed for assessing the entry rate of intact lactose into the portal circulation in newborn piglets. METHODS:In experiment 1, unlabeled and [D-1-(13C)]-lactose were infused into two separ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kien CL,Murray RD,Ailabouni AH,Habash DL,Powers PA

更新日期：1997-07-01 00:00:00

abstract：:Eicosanoids, derivatives of arachidonic acid, play a role in several inflammatory diseases of the bowel. To determine whether prostaglandin E2 (PGE2), leukotriene B4 (LTB4), and leukotriene C4D4E4 (LTC4D4E4), have a role in hypoxic insult to the intestine, we examined the levels of these mediators in a hypoxic neonata...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Dollberg S,Udassin R,Ginat-Israeli T,Weidenfeld J,Branski D

更新日期：1992-08-01 00:00:00

abstract：:Bacterial translocation is a phenomenon in which live bacteria cross the intestinal barrier. The definition may be broadened to include transmural passage of bacterial cell wall components such as lipopolysaccharide and peptidoglycan polysaccharide. After translocation, bacteria or their products reach the mesenteric ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Lichtman SM

更新日期：2001-07-01 00:00:00

abstract：:Portal hypertension, an expected consequence of cirrhosis, often has an insidious course in children. A noninvasive technique using abdominal sonography has been previously employed by several investigators as a means of diagnosing this condition. Their technique involves sonographically measuring the diameter of the ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Rabinowitz SS,Norton KI,Benkov KJ,Yeh HC,Leleiko NS

更新日期：1990-04-01 00:00:00

abstract：:R-1 anti-reticulin antibodies (ARA) were present in sera of 10 of the 12 children who subsequently fulfilled the ESPGAN diagnostic criteria for celiac disease (CD), but was not found in any children in the age-matched control groups, viz., severely malnourished (n = 20), acute gastroenteritis (n = 23), normally nouris...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Khoshoo V,Bhan MK,Unsworth DJ,Kumar R,Walker Smith JA

更新日期：1988-11-01 00:00:00

abstract：OBJECTIVES:In light of a paucity of data on the role of diet in colonoscopy preparation in paediatric population, the present study was designed to compare the effectiveness of clear liquid and low-fibre diets for breakfast and lunch on the day preceding colonoscopy in children. METHODS:This prospective, randomised tr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Mytyk A,Lazowska-Przeorek I,Karolewska-Bochenek K,Kakol D,Banasiuk M,Walkowiak J,Albrecht P,Banaszkiewicz A

更新日期：2018-05-01 00:00:00

abstract：:Sixteen children (3.5-14.7 years) with portal hypertension and variceal hemorrhage were treated by direct endoscopic variceal sclerotherapy. Follow-up clinical and endoscopic evaluations have been carried out over a 1-6-year period (mean, 2.3 years). Prior to sclerotherapy, three patients had undergone unsuccessful su...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Donovan TJ,Ward M,Shepherd RW

更新日期：1986-09-01 00:00:00

abstract：:Hypercalciuria and bone disease are frequently associated with total parenteral nutrition (TPN) in children and adults. The aim of this study was to assess the influence of calcium, phosphorus, and vitamin D intakes on hypercalciuria. We observed seven children aged 4-13 years receiving home cyclic TPN for 4 consecuti...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Larchet M,Garabédian M,Bourdeau A,Gorski AM,Goulet O,Ricour C

更新日期：1991-11-01 00:00:00

abstract：:The "high-mannose" glycosylated forms of aminopeptidase N (EC 3.4.11.2), maltase-glucoamylase (EC 3.2.1.20), and sucrase-isomaltase (EC 3.2.1.48, EC 3.2.1.10) have been purified. The high-mannose glycosylated form of sucrase-isomaltase was found to have a lower specific activity than the complex glycosylated form, whe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sjöström H,Norén O,Danielsen EM

更新日期：1985-12-01 00:00:00

abstract：:To further evaluate the nature of malnutrition, define at-risk groups, and confirm the efficacy of nutritional supplementation on body composition in cystic fibrosis (CF), we have conducted longitudinal and cross-sectional studies of total body potassium (TBK) in 161 unselected CF subjects aged 1 month to 17 years. TB...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Shepherd RW,Holt TL,Greer R,Cleghorn GJ,Thomas BJ

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVES:Lutein and zeaxanthin are dietary carotenoids that may influence visual and cognitive development. The objective of this study was to provide the first data on distribution of carotenoids in the infant brain and compare concentrations in preterm and term infants. METHODS:Voluntarily donated brain tissues fr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Vishwanathan R,Kuchan MJ,Sen S,Johnson EJ

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:This position paper written by the Hepatitis Expert Team of the Federation of International Societies of Pediatric Gastroenterology, Hepatology, and Nutrition aimed to systematically evaluate clinical practice guidelines (CPGs), medical consensus, and position papers on the use of direct-acting antivirals (DA...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Indolfi G,Fischler B,Gonzalez-Peralta RP,Ciocca M,Porta G,Neelam M,El-Guindi M,Kelly D,Ni YH,Sibal A,Leung DH,Chang MH,Hepatitis Expert Team of the Federation of International Societies of Pediatric Gastroenterology, Hepatology,

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND AND AIMS:The aim of the present study was to evaluate proinflammatory and anti-inflammatory cytokine levels in children with irritable bowel syndrome (IBS). PATIENTS AND METHODS:Thirty-five children with IBS (17 diarrhea-predominant, 7 constipation-predominant, and 11 mixed type) and 25 healthy children as ...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hua MC,Lai MW,Kuo ML,Yao TC,Huang JL,Chen SM

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES:The primary aim of this study was to describe and compare the clinical characteristics of 2 groups of children presenting to a feeding clinic: children with autism spectrum disorder (ASD) and children with a nonmedically complex history (NMC). A secondary aim was to compare participants according to the degr...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Marshall J,Hill RJ,Ware RS,Ziviani J,Dodrill P

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Hepatic lesions have been described in Alagille syndrome (ALGS) in isolated case reports, and most of these have been reported to be hepatocellular carcinoma. OBJECTIVES:The aim of the present study was to determine the frequency, imaging, and histopathologic characteristics of hepatic lesions in children w...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Alhammad A,Kamath BM,Chami R,Ng VL,Chavhan GB

更新日期：2016-02-01 00:00:00

abstract：:Severity scores are used to predict the outcome of acute pancreatitis (AP). Several scores are used in adult patients, but none has been thoroughly validated for specific use in paediatric patients. We retrospectively collected data from 48 children with AP (13 severe and 35 mild). The main causes were trauma (23%), i...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Fabre A,Petit P,Gaudart J,Mas E,Vial J,Olives JP,Sarles J

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:Loss of the complement inhibitor CD55 leads to a syndrome of early-onset protein-losing enteropathy (PLE), associated with intestinal lymphangiectasia and susceptibility to large-vein thrombosis. The in vitro and short-term treatment benefits of eculizumab (C5-inhibitor) therapy for CD55-deficiency have been...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kurolap A,Eshach Adiv O,Hershkovitz T,Tabib A,Karbian N,Paperna T,Mory A,Vachyan A,Slijper N,Steinberg R,Zohar Y,Mevorach D,Baris Feldman H

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:Failure-to-thrive is defined as an abnormally low weight and/or height for age. The term "nonorganic failure-to-thrive" (NOFT) has been used to describe "failure-to-thrive" without an obvious cause underlying the growth failure. The purpose of the present study was to compare sensory processing abilities bet...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Yi SH,Joung YS,Choe YH,Kim EH,Kwon JY

更新日期：2015-06-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to assess clinical presentation, endoscopic findings, antibiotic susceptibility and treatment success of Helicobacter pylori (H. pylori) infected pediatric patients. METHODS:Between 2013 and 2016, 23 pediatric hospitals from 17 countries prospectively submitted data on consecutive H...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kori M,Le Thi TG,Werkstetter K,Sustmann A,Bontems P,Lopes AI,Oleastro M,Iwanczak B,Kalach N,Misak Z,Cabral J,Homan M,Cilleruelo Pascual ML,Pehlivanoglu E,Casswall T,Urruzuno P,Martinez Gomez MJ,Papadopoulou A,Roma E,

更新日期：2020-10-01 00:00:00

abstract：:The apolipoprotein (apo) A-I:B ratio and the apo B concentration were determined by radial immunodiffusion in dried blood spot samples from 1,767 10- and 11-year-old children. Children with either apo A-I:B ratios below the first percentile or apo B levels above the 99th were recalled and plasma lipid and apolipoprote...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Sveger T,Fex G,Flodmark CE,Kjellström T,Borgfors N

更新日期：1990-02-01 00:00:00

abstract：:Parents and caretakers are increasingly feeding infants and young children plant-based "milk" (PBM) alternatives to cow milk (CM). The US Food and Drug Administration currently defines "milk" and related milk products by the product source and the inherent nutrients provided by bovine milk. Substitution of a milk that...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Merritt RJ,Fleet SE,Fifi A,Jump C,Schwartz S,Sentongo T,Duro D,Rudolph J,Turner J,NASPGHAN Committee on Nutrition.

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Achalasia is rare in children. Recently, injection of botulinum toxin into the lower esophageal sphincter has been studied as an alternative to esophageal pneumatic dilatation or surgical myotomy as treatment for achalasia. In the current study, the effects of botulinum toxin were investigated in the largest...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Hurwitz M,Bahar RJ,Ament ME,Tolia V,Molleston J,Reinstein LJ,Walton JM,Erhart N,Wasserman D,Justinich C,Vargas J

更新日期：2000-05-01 00:00:00

abstract：:We evaluated the role of initial iron stores on iron accumulation during recovery from severe edematous protein-energy malnutrition in children. Twenty-six preschool children were divided in two groups according to their initial iron reserves, as estimated from serum ferritin concentration, using a cutoff criterion of...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Caballero B,Solomons NW,Batres R,Torún B

更新日期：1985-02-01 00:00:00

abstract：BACKGROUND:Lactobacillus plantarum is a Gram-positive bacillus known for its effect as a probiotic agent. The goal of the study was to determine whether L. plantarum is capable of inhibiting the transepithelial neutrophil migration induced by enteropathogenic Escherichia coli (EPEC). METHODS:Cultured intestinal epithe...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Michail S,Abernathy F

更新日期：2003-03-01 00:00:00

abstract：:Esophagitis induced by medications has been recognized in adults but rarely in children. A child with hemorrhagic esophagitis resulting from taking doxycycline tablets for treatment is described and the pathophysiology of this condition is discussed. In pediatric cases treated by tablets or capsules, the possibility o...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Kato S,Kobayashi M,Sato H,Saito Y,Komatsu K,Harada Y

更新日期：1988-09-01 00:00:00

abstract：:To evaluate the prevalence and duration of viremia in relation to the features of liver disease, we investigated hepatitis B virus (HBV) DNA by the polymerase chain reaction in the serum of 39 children with chronic hepatitis B, after hepatitis B e antigen to antibody seroconversion. During a mean observation period of...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Bortolotti F,Wirth S,Crivellaro C,Alberti A,Martine U,de Moliner L

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Childhood overweight has become a serious health problem among children and adolescents in the United States. No previous study, to our knowledge, has analyzed the effect of body mass index (BMI) on range of motion and carrying angle of the elbow joint in a healthy pediatric population. The primary objective...

journal_title：Journal of pediatric gastroenterology and nutrition

authors： Golden DW,Wojcicki JM,Jhee JT,Gilpin SL,Sawyer JR,Heyman MB

更新日期：2008-02-01 00:00:00