Radial organisation of neurons and dendrites in human cortical areas 25, 32, and 32'.

abstract：:The mRNA level of the 17-kDa protein neurogranin (NG), a postsynaptic substrate of the protein kinase C, has previously been found to be decreased in rat forebrain after 24-h sleep deprivation (SD). To investigate the functional significance of this finding in various forebrain regions, the effect of 24-h SD on the mR...

journal_title：Brain research

authors： Neuner-Jehle M,Rhyner TA,Borbély AA

更新日期：1995-07-10 00:00:00

abstract：:The effects of lateral hypothalamic (LH) lesions were studied in golden-mantled ground squirrels, Spermophilus lateralis, a species of mammalian hibernator that displays endogenous circannual body weight cycles when kept in constant conditions. The lesions were made during the weight-gain phase. Evidence that the lesi...

journal_title：Brain research

authors： Mrosovsky N,Hallonquist JD

更新日期：1986-12-10 00:00:00

abstract：:Extracellular recordings were carried out in the primary visual cortex of behaving macaque monkeys. Neurons were activated by moving a visual stimulus across their receptive fields during periods of steady fixation and by moving their receptive fields (by visual tracking) across a motionless visual stimulus, taking ca...

journal_title：Brain research

authors： Galletti C,Squatrito S,Battaglini PP,Grazia Maioli M

更新日期：1984-05-28 00:00:00

abstract：:Statistical analysis techniques that permit detection and quantification of EEG-single unit correlations were employed in a study of generalized penicillin epilepsy in the cat. Single unit activity was recorded in cerebral and cerebellar cortices and compared to the locally recorded EEG. It was found that during gener...

journal_title：Brain research

authors： Wray DV,Hablitz JJ

更新日期：1978-10-13 00:00:00

abstract：:Rats were administered haloperidol (0.5 mg/kg/day) for 21 days. Twenty percent of locus coeruleus (LC) neurons recorded were not spontaneously active, while no such neuron was observed in control animals. A further 22% of neurons (spontaneously active) had rates greater than 2 standard deviations from the mean of LC c...

journal_title：Brain research

authors： Dinan TG,Aston-Jones G

更新日期：1985-01-28 00:00:00

abstract：:We compared changes in levels of substance P-like immunoreactivity (SPLI) in L4-6 dorsal root ganglia (DRG), L4-6 dorsal roots, sciatic nerve, tibial nerve and hind foot skin in rats following resection or crush injury of the sciatic nerve. The initial depletion of SPLI, which occurred in all areas sampled, was simila...

journal_title：Brain research

authors： Bisby MA,Keen P

更新日期：1986-02-12 00:00:00

abstract：:Multiple sigma receptor subtypes have been identified in the hippocampus, yet their physiological role remains largely undefined. In the current study, we examined the role of sigma receptors in the regulation of N-methyl-D-aspartate (NMDA)-stimulated [3H]norepinephrine ([3H]NE) release from rat hippocampal slices. Bo...

journal_title：Brain research

authors： Gonzalez-Alvear GM,Werling LL

更新日期：1995-02-27 00:00:00

abstract：:Fluctuation analysis has been used to study the influence of temperature on the conductance and mean open time of Cl- permeable ion channels induced by gamma-aminobutyric acid (GABA) and glycine in the membrane of tissue cultured mouse spinal neurons. The conductance of GABA- and glycine-activated channels increased s...

journal_title：Brain research

authors： Mathers DA,Barker JL

更新日期：1981-11-16 00:00:00

abstract：:Brain injury accelerates amyloid-β (Aβ) deposits and exacerbates Alzheimer's disease (AD). Accumulation of intracellular soluble Aβ impairs cognition prior to emergence of Aβ plaques. However, it is not known whether brain injury affects learning impairment attributable to intracellular soluble Aβ. We made a small inj...

journal_title：Brain research

authors： Zou J,Wang M,Uchiumi O,Shui Y,Ishigaki Y,Liu X,Tajima N,Akai T,Iizuka H,Kato N

更新日期：2016-04-15 00:00:00

abstract：:Activated monocytes/macrophages are known to release toxic materials. Identification of these materials is important for developing more effective treatments for inflammatory disorders where self attack occurs. We stimulated human monocytes and THP-1 cells with LPS/IFNγ and measured the toxic effects of their conditio...

journal_title：Brain research

authors： Lee M,Suk K,Kang Y,McGeer E,McGeer PL

更新日期：2011-07-11 00:00:00

abstract：:Using the rapid Golgi method, the morphology of dendritic spines was quantified in the calyxes of groups of newly emerged, nurse, and forager honeybees. These groups were studied because they represented distinct stages of behavioral development and cumulative experience which, according to recent vertebrate findings,...

journal_title：Brain research

authors： Coss RG,Brandon JG,Globus A

更新日期：1980-06-16 00:00:00

abstract：:The present investigation is aimed at studying the influence of the striate cortex (area 17 or V1) upon responses of area 18a. Electrical activity was recorded from neurons in area 18a through glass micropipettes. At the same time lidocaine hydrochloride was injected in the same retinotopic register of area 17. Forty ...

journal_title：Brain research

authors： Molotchnikoff S,Hubert F

更新日期：1990-03-05 00:00:00

abstract：:Gonadal steroids are thought to act by activation of the genome following cytoplasmic binding, translocation of the hormone--receptor complex to the nucleus and chromatin binding at specific acceptor sites. This study examined the kinetics of chromatin binding of estradiol by hypothalamic and cortical cells of adult g...

journal_title：Brain research

authors： Whalen RE,Olsen KL

更新日期：1978-08-18 00:00:00

abstract：:Receptor subunit composition is believed to play a major role in the synaptic trafficking of AMPA receptors (AMPARs), and thus in activity-dependent synaptic plasticity. To isolate a physiological role of GluA1-containing AMPARs in area CA3 of the hippocampus, pair recordings were performed in organotypic hippocampal ...

journal_title：Brain research

authors： Selcher JC,Xu W,Hanson JE,Malenka RC,Madison DV

更新日期：2012-01-30 00:00:00

abstract：:Rats with bilateral striatal cholinergic lesions induced by the neurotoxin AF64A were found to have increased spontaneous nocturnal locomotor activity as measured in terms of the amount of time spent moving, the total distance traveled and the number of episodes and time of stereotypic behaviors. No significant differ...

journal_title：Brain research

authors： Sandberg K,Sanberg PR,Coyle JT

更新日期：1984-05-14 00:00:00

abstract：:Disturbed synaptic transmission contributes to the pathophysiology of mood disorders. Post mortem studies reported reduced expression of the synaptic vesicle protein (SVP) complexins I and II in depression. Antidepressants were found to induce the expression of these genes. Since animals with congenital susceptibility...

journal_title：Brain research

authors： Zink M,Vollmayr B,Gebicke-Haerter PJ,Henn FA,Thome J

更新日期：2007-05-04 00:00:00

abstract：:The effect of cerebellar stimulation on the accommodation of the lens was examined in anesthetized cats. An infrared optometer was used to measure the refractive power of the lens during stimulation of the cerebellum. The area giving responses within latencies shorter than 160 msec and amplitudes larger than 0.15 diop...

journal_title：Brain research

authors： Hosoba M,Bando T,Tsukahara N

更新日期：1978-09-29 00:00:00

abstract：:As in many humans suffering from lupus erythematosus, the development of systemic autoimmunity and inflammation in Fas-deficient MRL-lpr mice is accompanied by CNS dysfunction of unknown etiology. Experimental studies revealed infiltration of lymphoid cells into the choroid plexus, reduced neuronal complexity, retarde...

journal_title：Brain research

authors： Ballok DA,Millward JM,Sakic B

更新日期：2003-02-28 00:00:00

abstract：:The effects of a sensorimotor task on ipsilateral primary motor cortex (ipsi-M1) excitability mediated via the transcallosal pathway, including the changes in short-interval intracortical inhibition (SICI) and intracortical facilitation (ICF), were examined in ten right-handed subjects. Transcranial magnetic stimulati...

journal_title：Brain research

authors： Morishita T,Ninomiya M,Uehara K,Funase K

更新日期：2011-01-31 00:00:00

abstract：:Glioblastoma (GBM) is a highly heterogeneous and aggressive brain tumor. Comprehensive genomic and transcriptomic analyses revealed that GBM segregates into three subgroups with characteristic signaling pathways. The Wnt pathway recently received increasing attention with the recognition of its importance in tumor dev...

journal_title：Brain research

authors： Tompa M,Nagy A,Komoly S,Kalman B

更新日期：2019-09-01 00:00:00

abstract：:p-Chlorophenylalanine was administered to rats to inhibit hepatic phenylalanine hydroxylase activity. Two days later, phenylalanine injection was noted to produce substantial increases in serum phenylalanine levels, and relatively modest increments in serum tyrosine levels. Rats injected with p-chlorophenylalanine 2 d...

journal_title：Brain research

authors： Fernstrom MH,Baker RL,Fernstrom JD

更新日期：1989-10-16 00:00:00

abstract：:Data from several laboratories indicate that cerebral endothelial cells possess cell surface receptors for numerous vasoactive agents including angiotensin II (AII) and atrial natriuretic factor (ANF). The intracellular messengers of these receptors as well as possible receptor interactions were explored. ANF increase...

journal_title：Brain research

authors： Grammas P,Giacomelli F,Bessert D,Wiener J

更新日期：1991-10-18 00:00:00

abstract：:The use of two different radioligands, [125I]Leu8, D-Tryp22,Tyr25-somatostatin-28 and the stable somatostatin octapeptide analog [125I]204-090, D-Phe-Cys[125I]Tyr-D-Trp-Lys-Thr-Cys-Thr(ol), allowed to differentiate between two somatostatin receptor subpopulations in the human cortex. In homogenates, octapeptide somato...

journal_title：Brain research

authors： Reubi JC,Probst A,Cortés R,Palacios JM

更新日期：1987-03-17 00:00:00

abstract：:Brain-derived angiotensin II (ANG II) and prostaglandins have important roles in the regulation of body fluid and blood pressure homeostasis. In the present studies we investigated the central interactions between these two neurochemical products in regulating the hypothalamo-neurohypophysial system during dehydration...

journal_title：Brain research

authors： Kadekaro M,Terrell ML,Bui V,Summy-Long JY

更新日期：2001-01-19 00:00:00

abstract：:Fast cyclic voltammetry (FCV) at carbon fibre microelectrodes was used to monitor stimulated noradrenaline (NA) efflux in slices of the ventral part of the rat bed nucleus of stria terminalis (BSTV) superfused with artificial cerebrospinal fluid at 32 degrees C. NA efflux was evoked by local electrical stimulation (tr...

journal_title：Brain research

authors： Palij P,Stamford JA

更新日期：1993-04-02 00:00:00

abstract：:Injection of a potent, cholinergic muscarinic antagonist, [3H]3-quinuclidinyl benzilate ([3H]QNB), results in a localization of the drug to muscarinic receptors in rat brain. The distribution of these drug receptors was examined in various brain regions previously thought to contain cholinergic neurons. They were loca...

journal_title：Brain research

authors： Kuhar M,Yamamura HI

更新日期：1976-07-09 00:00:00

abstract：:Chronic developmental exposure to ethanol can lead to a wide variety of teratogenic effects, which in humans are known as fetal alcohol spectrum disorders (FASD). Individuals affected by FASD may exhibit persistent impairments to cognitive functions such as learning, memory, and attention, which are highly dependent o...

journal_title：Brain research

authors： Louth EL,Luctkar HD,Heney KA,Bailey CDC

更新日期：2018-01-01 00:00:00

abstract：:Field potentials (FP) recorded from the surface of toad's optic tectum (OT) to electrical stimulation of the contralateral optic nerve (ON) show initial positive deflections P*, followed by negative wave N and positive wave P; the former result from axonal inputs, the latter two resemble excitatory and inhibitory post...

journal_title：Brain research

authors： Schwippert WW,Ewert JP

更新日期：1995-01-09 00:00:00

abstract：:Recent research suggests that attributing human movement to ambiguous and static Rorschach stimuli (M responses) is associated with EEG mu suppression, and that disrupting the left inferior gyrus (LIFG; a putative area implicated in mirroring activity) decreases the tendency to see human movement when exposed to the R...

journal_title：Brain research

authors： Ando' A,Pineda JA,Giromini L,Soghoyan G,QunYang,Bohm M,Maryanovsky D,Zennaro A

更新日期：2018-02-01 00:00:00

abstract：:A total of 183 nucleus basalis of Meynert (NBM) neurons were recorded in a monkey performing a delayed response task. Significant changes in discharge rate were detected in 74% of the NBM cells sampled with most responses occurring in the choice (64%) or the reward (67%) epochs of the task. Neuronal responses in the c...

journal_title：Brain research

authors： Richardson RT,DeLong MR

更新日期：1986-12-10 00:00:00