Abstract：
:The effects of lateral hypothalamic (LH) lesions were studied in golden-mantled ground squirrels, Spermophilus lateralis, a species of mammalian hibernator that displays endogenous circannual body weight cycles when kept in constant conditions. The lesions were made during the weight-gain phase. Evidence that the lesions were well placed included interruption of weight gain, transient aphagia, disrupted nest building, increased spillage of food crumbs and in some cases abnormal postures or movement. Despite these deficits most animals survived. Their body weights at the first postoperative peak of the cycle recovered either to within the control range (Experiment 1) or close to preoperative peak levels (Experiment 2). There was no evidence that the lesions lowered set points. The rapid recovery of weight and eating by ground squirrels given only dry rodent chow, after large lesions (1.5-2.5 mA, DC anodal, 15-25 s), contrasts with what is seen in rats following LH lesions.
journal_name
Brain Resjournal_title
Brain researchauthors
Mrosovsky N,Hallonquist JDdoi
10.1016/0006-8993(86)91518-0subject
Has Abstractpub_date
1986-12-10 00:00:00pages
282-95issue
2eissn
0006-8993issn
1872-6240pii
0006-8993(86)91518-0journal_volume
399pub_type
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