Immunohistochemical detection of mutant p53-suppressor gene product in patients with breast cancer: influence on metastasis-free survival.

abstract：:The aim of this study was to evaluate the usefulness of image-guided robotic stereotactic radiosurgery for the local control of unresectable liver metastases from colorectal and non-colorectal cancer. Twenty-seven consecutive patients (median age 62 years, range 47-80 years) with liver metastases considered unsuitable...

journal_title：Anticancer research

authors： Ambrosino G,Polistina F,Costantin G,Francescon P,Guglielmi R,Zanco P,Casamassima F,Febbraro A,Gerunda G,Lumachi F

更新日期：2009-08-01 00:00:00

abstract：:African-American women with breast cancer consistently show a shortened survival when compared with Caucasians with breast cancer, however it is not clear whether this is due to socioeconomic factors or to racial differences in tumor biology. Cyclin D1 overexpression has been demonstrated in 60-80% of female breast ca...

journal_title：Anticancer research

authors： Joe AK,Arber N,Bose S,Heitjan D,Zhang Y,Weinstein IB,Hibshoosh H

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is expressed by immune cells and has been shown to play an important role in tumor surveillance due to its ability to induce apoptosis in various transformed cells. Interferon gamma (IFN-gamma), a multipotent cytokine with broad stimulatory effe...

journal_title：Anticancer research

authors： Langaas V,Shahzidi S,Johnsen JI,Smedsrød B,Sveinbjørnsson B

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:The use of prophylactic cranial irradiation (PCI) to treat brain metastases (BM) in non-small cell lung cancer (NSCLC) is restricted due to the potential associated toxicity and lack of survival benefit. BM can have a negative impact on neurocognitive function (NF) and quality of life (QOL). The aim of this ...

journal_title：Anticancer research

authors： Precival C,Landy M,Poole C,Mullaney L

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND/AIM:Even though prostate cancer (PCa) has good prognosis, there is a discrepancy in the risk among ethnic groups, with high morbidity in African American men. Single nucleotide polymorphisms (SNPs) in interleukin 10 (IL-10) have been associated with inflammation and cancer risk. We investigated the associati...

journal_title：Anticancer research

authors： Abbas M,Mason T,Ibad A,Khraiwesh M,Apprey V,Kanaan Y,Wilson B,Dunston G,Ricks-Santi L,Brim H

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIM:This study's aim was to investigate the safety and effectiveness of asunaprevir and daclatasvir treatment for recurrent hepatitis C virus (HCV) infection in transplant recipients. The study cohort comprised 14 transplant recipients with recurrent hepatitis C who were receiving asunaprevir and daclatasvir...

journal_title：Anticancer research

authors： Harada N,Yoshizumi T,Ikegami T,Itoh S,Furusho N,Kato M,Shimoda S,Fukuhara T,Soejima Y,Maehara Y

更新日期：2018-09-01 00:00:00

abstract：:There is sparse information about cancer in the axillary tail of Spence (CATS). Eight hundred and thirty-nine patients with breast cancer were retrospectively studied for the occurrence of CATS. Ten patients were identified based on detection by imaging studies. A tendency towards stage II or III disease, and estrogen...

journal_title：Anticancer research

authors： Ampil F,Caldito G,Henderson B,Li B,Kim RH,Burton G,Chu Q

更新日期：2012-09-01 00:00:00

abstract：AIM:The purpose of the present study was the analysis of the relationship between tumor necrosis factor-α (TNF-α) -308 G/A and cervical intraepithelial neoplasia (CIN). MATERIALS AND METHODS:A prospective case-control study was performed, enrolling 78 cases of cervical intraepithelial neoplasia and 107 controls. Every...

journal_title：Anticancer research

authors： Rotar IC,Muresan D,Radu P,Petrisor F,Apostol S,Mariana T,Butuza C,Stamatian F

更新日期：2014-01-01 00:00:00

abstract：:Screening for hereditary tumours provides a basis for secondary prevention. In 1985, the Foundation for the Detection of Hereditary Tumours was established in The Netherlands to coordinate screening in families with hereditary tumours. In the initial period of four years a large number of families were collected. Regi...

journal_title：Anticancer research

authors： Vasen HF,Griffioen G,Lips CJ,Struyvenberg A,van Slooten EA

更新日期：1990-03-01 00:00:00

abstract：AIM:To examine patterns of clinical practice in locally advanced esophageal cancer among US radiation oncologists after publication of the CROSS trial. MATERIALS AND METHODS:US radiation oncologists were surveyed on 13 questions pertaining to the management of esophageal cancer. Respondents' demographics and their cli...

journal_title：Anticancer research

authors： Elliott DA,Rana SR,Nabavizadeh N,Chen Y,Kusano A,Holland JM,Mitin T

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Most patients with pancreatic adenocarcinoma are diagnosed with locally advanced (unresectable) or metastatic disease. The aim of this study was to investigate possible prognostic factors of survival in such patients. PATIENTS AND METHODS:Two hundred and fifteen patients were studied retrospectively. Twenty...

journal_title：Anticancer research

authors： Papadoniou N,Kosmas C,Gennatas K,Polyzos A,Mouratidou D,Skopelitis E,Tzivras M,Sougioultzis S,Papastratis G,Karatzas G,Papalambros E,Tsavaris N

更新日期：2008-01-01 00:00:00

abstract：:MG132, a proteasome inhibitor, has been shown to induce apoptotic cell death through formation of reactive oxygen species (ROS). Here, we evaluated the effects of MG132 on the growth of endothelial cells, especially calf pulmonary artery endothelial cells (CPAECs). MG132 dose-dependently inhibited the growth of CPAECS...

journal_title：Anticancer research

authors： Han YH,Moon HJ,You BR,Yang YM,Kim SZ,Kim SH,Park WH

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND:Loss of heterozygosity (LOH) may be a valuable tool for detection of malignant proceedings. The aim of our study was to investigate LOH in the serum of patients with adenocarcinoma of the distal oesophagus and the cardia for diagnostic and prognostic utility. PATIENTS AND METHODS:Matched tumour and serum sa...

journal_title：Anticancer research

authors： Wachowiak R,Kaifi JT,Schurr PG,Merkert P,Yekebas E,Schwarzenbach H,Strate T,Sauter G,Izbicki JR

更新日期：2007-01-01 00:00:00

abstract：:Between January 1996 and June 2000, 192 men with prostate cancer underwent radical retropubic prostatectomy (RP) and bilateral pelvic node dissection in 26 centers participating in the Italian randomized prospective TAP study. The reviewing pathologist evaluated 145 RP specimens. Seventy-five cases had not been treate...

journal_title：Anticancer research

authors： Mazzucchelli R,Montironi R,Prezioso D,Bono AV,Ferrari P,Manganelli A,Morelli P,De Vito ML,Santinelli A,Diamanti L,Lotti T,Polito M,Takeda Italian TAP Study Group.

更新日期：2001-09-01 00:00:00

abstract：:The effects of two gallium (Ga) compounds, Ga chloride (GaCl3) and tris(8-quinolinolato)Ga (III) on the viability of A549 human malignant lung adenocarcinoma cells were investigated. The results demonstrated that both drugs reduced the viability of A549 cells but to different extents. The inhibitory effects of tris(8-...

journal_title：Anticancer research

authors： Collery P,Lechenault F,Cazabat A,Juvin E,Khassanova L,Evangelou A,Keppler B

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Cervical cancer prevention is performed by taking Pap smears. The correct execution of the smear is crucial as an inadequate smear might result in underdiagnosis. The second means of cervical cancer prevention is visual inspection of the cervix uteri with acetic acid, while often both methods are combined. W...

journal_title：Anticancer research

authors： Hoellen F,Bohlmann MK,Brade J,Rody A,Diedrich K,Husstedt WD,Hornemann A

更新日期：2013-03-01 00:00:00

abstract：AIM:Brucea javanica was studied to identify nuclear factor kappaB (NF-κB) inhibitors exhibiting reactive oxygen species (ROS) intracellular amplification. MATERIAL AND METHODS:Eight compounds were evaluated for selective cytotoxicity using HT-29, HeLa, and HL-60 cells, and in a NF-κB assay. Active compounds were then ...

journal_title：Anticancer research

authors： Kim JA,Lau EK,Pan L,De Blanco EJ

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:Ethanol injection is widely used in liposome preparation. However, the parameters determining particle size distribution of the liposomal preparation has not been fully defined. MATERIALS AND METHODS:A syringe pump-driven microfluidic injection device was used to produce liposomes under different conditions...

journal_title：Anticancer research

authors： Pradhan P,Guan J,Lu D,Wang PG,Lee LJ,Lee RJ

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND/AIM:The aim of the present study was to clarify if the degree of hepatic infiltration and lymph node swelling of gallbladder carcinoma (GBC) should be held as deciding factors for T2-4 GBC patients to undergo surgery. PATIENTS AND METHODS:Fifty consecutive patients with T2-4 GBC who underwent surgery were r...

journal_title：Anticancer research

authors： Okada K,Kawai M,Ueno M,Hirono S,Miyazawa M,Hayami S,Shimizu A,Shigekawa Y,Kitahata Y,Miyamoto A,Yamaue H

更新日期：2016-06-01 00:00:00

abstract：:The usefulness of lymphocyte subset change as an indicator for predicting survival time and the effectiveness of combined treatment with an immunopotentiator, lentinan, and carboplatin (CBDCA) were investigated. Of 13 patients with advanced unresectable cancer entered in this study, 9 were administered 2 mg/body lenti...

journal_title：Anticancer research

authors： Matsuoka H,Yano K,Seo Y,Saito T,Tomoda H,Tsurumoto S

更新日期：1995-09-01 00:00:00

abstract：:Matrix metalloproteinase-7 (MMP-7), MMP-9, MMP-13, and tissue inhibitor of matrix metalloproteinase-1 (TIMP-1) are considered to have important roles in the invasiveness and outcomes of colorectal cancer (CRC). This study examined the clinicopathological significance of the relative expression of these genes in patien...

journal_title：Anticancer research

authors： Yamada T,Oshima T,Yoshihara K,Tamura S,Kanazawa A,Inagaki D,Yamamoto N,Sato T,Fujii S,Numata K,Kunisaki C,Shiozawa M,Morinaga S,Akaike M,Rino Y,Tanaka K,Masuda M,Imada T

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Since superparamagnetic iron oxide nanoparticles (SPION) possess unique features, they provide a huge platform for medical applications, especially for cancer diagnosis and therapy (e.g. imaging, and drug targeting). However, heterogeneous effects on mammalian cells with regard to reproductive tissue are des...

journal_title：Anticancer research

authors： Pöttler M,Hofmann S,Dürr S,Unterweger H,Wiest I,Zaloga J,Alexiou C,Jeschke U,Janko C

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND/AIM:Omega 3 polyunsaturated fatty acids (PUFAs) have been shown to inhibit the induction and progression of many tumor types. The aim of this study was to determine the anticancer effect of docosahexaenoic acid monoglyceride (MAG-DHA) alone and in combination with the chemotherapeutic agent carboplatin (CBT)...

journal_title：Anticancer research

authors： Morin C,Fortin S

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Positron emission tomography-computed tomography (PET-CT) is currently not established in the management of recurrent ovarian cancer. Here, its value in diagnosis and therapy planning was evaluated. PATIENTS AND METHODS:Seventy patients received PET-CT for suspicion of recurrent ovarian cancer. PET-CT and s...

journal_title：Anticancer research

authors： Lenhard MS,Burges A,Johnson TR,Stieber P,Kümper C,Ditsch N,Linke R,Friese K

更新日期：2008-07-01 00:00:00

abstract：:A pilot study to evaluate the predictive value of Indium-111-labelled somatostatin analogue [DTPA-D-Phe1]-octreotide scintigraphy (OctreoScan111) in the Octreotide treatment of hormone-refractory prostatic adenocarcinoma was initiated. Ten patients were investigated with OctreoScan111 with regard to disease extension ...

journal_title：Anticancer research

authors： Kälkner KM,Nilsson S,Westlin JE

更新日期：1998-01-01 00:00:00

abstract：:Cisplatin is one of the most widely used and effective chemotherapeutic agents for the treatment of several human malignancies. Although the effectiveness of cisplatin is high, its toxicities justify the demand for improved formulations of this drug. A liposomal formulation of cisplatin, Lipoplatin, was developed in o...

journal_title：Anticancer research

authors： Devarajan P,Tarabishi R,Mishra J,Ma Q,Kourvetaris A,Vougiouka M,Boulikas T

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND/AIM:The aim of this study was to determine the natural history of benign thyroid nodules using ultrasonography. PATIENTS AND METHODS:The records of 223 patients with benign thyroid nodules treated at the Kochi Medical School from 2010 to 2012 were reviewed retrospectively. Repeated ultrasonography was perfo...

journal_title：Anticancer research

authors： Oki T,Sugimoto T,Ogawa M,Dabanaka K,Namikawa T,Hanazaki K

更新日期：2019-04-01 00:00:00

abstract：:Between 1981 and 1987, 533 patients from 9 institutions were entered in a randomized trial to assess the value of adjuvant perioperative portal infusion with Fluorouracil and Mitomycin as compared to radical surgery alone. Analysis of 469 evaluable patients at a median follow-up of 5.8 years revealed 110 recurrences i...

journal_title：Anticancer research

authors： Weber W,Laffer U,Metzger U

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Primary ocular adnexal mucosa-associated lymphoid tissue lymphoma (POAML) is a rare disease. The purpose of this study was to evaluate the treatment outcome and patterns of failure of patients with early-stage POAML treated with radiotherapy. PATIENTS AND METHODS:From 1995 to 2008, 53 patients with early-st...

journal_title：Anticancer research

authors： Ohga S,Nakamura K,Shioyama Y,Sasaki T,Yoshitake T,Atsumi K,Terashima K,Asai K,Matsumoto K,Yoshikawa H,Kawano Y,Honda H

更新日期：2013-12-01 00:00:00

abstract：:Radiation therapy is essential for local tumor control for many types of cancer histologies. Technological advancements in recent years have allowed for precise irradiation of target tissues while minimizing the dose to non-target tissues. To enhance radiation damage to cancer cells and further limit the radiation eff...

journal_title：Anticancer research

authors： Linam J,Yang LX

更新日期：2015-05-01 00:00:00