Influence of acetic acid on a pap smear of dysplastic lesion.

Abstract:

BACKGROUND:Cervical cancer prevention is performed by taking Pap smears. The correct execution of the smear is crucial as an inadequate smear might result in underdiagnosis. The second means of cervical cancer prevention is visual inspection of the cervix uteri with acetic acid, while often both methods are combined. We investigated whether the application of acetic acid compromises the Pap smear. PATIENTS AND METHODS:A total of 100 patients with dysplasia were prospectively included; Pap smears were obtained before and after the application of acetic acid. RESULTS:We observed an alteration of the result of the Pap smear after acetic acid application in 41%. However, these alterations did not result in a dysplastic case being classed as a normal smear or vice versa. CONCLUSION:The application of acetic acid to the transformation zone of the cervix uteri may enhance changes of the Pap smear in dysplasia, however, the changes affect subgroups of dysplasia and thus do not change therapeutic management.

journal_name

Anticancer Res

journal_title

Anticancer research

authors

Hoellen F,Bohlmann MK,Brade J,Rody A,Diedrich K,Husstedt WD,Hornemann A

subject

Has Abstract

pub_date

2013-03-01 00:00:00

pages

1125-30

issue

3

eissn

0250-7005

issn

1791-7530

pii

33/3/1125

journal_volume

33

pub_type

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