Abstract:
BACKGROUND/AIM:The aim of this study was to determine the natural history of benign thyroid nodules using ultrasonography. PATIENTS AND METHODS:The records of 223 patients with benign thyroid nodules treated at the Kochi Medical School from 2010 to 2012 were reviewed retrospectively. Repeated ultrasonography was performed, and the findings were directly compared with previous images. RESULTS:The median change in the size of the nodules was 0.01 cm/year, although the size of six nodules (2.7%) increased more than 0.5 cm/year, and these nodules were removed surgically. Nineteen patients (8.5%) underwent surgery during the follow-up period. Compared to those who did not undergo surgery, the size of the nodules was larger and the rate of change in nodule diameter was higher in those undergoing surgery. The pathological diagnosis based on repeated fine needle aspiration cytology was benign nodules in 16 patients and papillary cancer in three patients. CONCLUSION:Even if a thyroid nodule is initially diagnosed as benign, it may have malignant potential. Therefore, so as not to miss malignancies, nodules should be carefully re-evaluated to assess their growth or change in size using ultrasonography.
journal_name
Anticancer Resjournal_title
Anticancer researchauthors
Oki T,Sugimoto T,Ogawa M,Dabanaka K,Namikawa T,Hanazaki Kdoi
10.21873/anticanres.13317subject
Has Abstractpub_date
2019-04-01 00:00:00pages
2061-2067issue
4eissn
0250-7005issn
1791-7530pii
39/4/2061journal_volume
39pub_type
杂志文章abstract:BACKGROUND:Transforming growth factor beta (TGF-beta) plays a complex role in breast carcinogenesis. Initially functioning as a tumor suppressor, this cytokine later contributes to the progression of malignant cells by enhancing their invasive and metastatic potential as well as suppressing antitumor immunity. The purp...
journal_title:Anticancer research
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journal_title:Anticancer research
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
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pub_type: 历史文章,杂志文章
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更新日期:2016-01-01 00:00:00
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journal_title:Anticancer research
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journal_title:Anticancer research
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doi:
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journal_title:Anticancer research
pub_type: 杂志文章
doi:
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journal_title:Anticancer research
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doi:
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更新日期:2010-12-01 00:00:00
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journal_title:Anticancer research
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doi:
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journal_title:Anticancer research
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doi:
更新日期:2002-11-01 00:00:00
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journal_title:Anticancer research
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doi:
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doi:
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doi:
更新日期:1999-01-01 00:00:00
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更新日期:2015-11-01 00:00:00
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更新日期:2014-06-01 00:00:00
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journal_title:Anticancer research
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