[111In-DTPA-D-Phe1]-octreotide scintigraphy in patients with hormone-refractory prostatic adenocarcinoma can predict therapy outcome with octreotide treatment: a pilot study.

abstract：AIM:To assess outcomes in patients treated with first-line bevacizumab-containing therapy for human epidermal growth factor receptor (HER)2-negative metastatic breast cancer (mBC) at a single centre with a homogenous standard-of-care. PATIENTS AND METHODS:Information on patient and disease characteristics, efficacy, a...

journal_title：Anticancer research

authors： Dieras V,Pop S,Berger F,Dujaric ME,Beuzeboc P,Escalup L,Bidard FC,Cottu PH,LE Tourneau C,Piperno-Neumann S,Laurence V,Robain M,Asselain B,Pierga JY

更新日期：2017-03-01 00:00:00

abstract：:The anticancer effects of retinoids have been recognized both in vivo and in vitro; however, little is known about their mechanism of action. Our study evaluated the effects of retinoic acid on the invasiveness of four human melanoma cell lines in vitro and showed a time-dependent inhibition of the ability of these ce...

journal_title：Anticancer research

authors： Wood WR,Seftor EA,Lotan D,Nakajima M,Misiorowski RL,Seftor RE,Lotan R,Hendrix MJ

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND/AIM:The amino acid positron emission tomography (PET) tracer [(18)F]-3-fluoro-alpha-methyltyrosine ((18)F-FAMT) is known to be highly specific for malignancies. We evaluated the accumulation of (18)F-FDG or (18)F-FAMT in lymph nodes (LN) prior to definitive chemoradiotherapy (CRT) for esophageal cancer. PAT...

journal_title：Anticancer research

authors： Sohda M,Miyazaki T,Honjyo H,Hara K,Ozawa D,Suzuki S,Tanaka N,Sano A,Sakai M,Yokobori T,Nakajima M,Fukuchi M,Kato H,Higuchi T,Tsushima Y,Kuwano H

更新日期：2014-12-01 00:00:00

abstract：:The production of amyloid beta protein precursor (APP), which is a potent inhibitor of matrix metalloproteinases and serine proteinases, in human astrocytic tumors (n = 17) and normal brain tissues (n = 3) was investigated. We found proteinase inhibitory activity at around 120 kD by trypsin reverse zymography in the c...

journal_title：Anticancer research

authors： Nakagawa T,Kabuto M,Kubota T,Kodera T,Sato K

更新日期：1999-07-01 00:00:00

abstract：:From 1980 to 1987, 243 evaluable patients with pT1, pT2 (less than 3 centimeters in diameter), N0, M0, invasive breast cancer were treated with "quadrantectomy" with axillary dissection followed by electron beam radiation therapy (QUART) at the St. Bortolo Hospital, Vicenza. Stage II patients received adjuvant chemoth...

journal_title：Anticancer research

authors： Gasparini G,Panizzoni GA,Dal Fior S,Germani B,Dall'Antonia F,Segato G,Meli S,Pozza F

更新日期：1991-07-01 00:00:00

abstract：:Melanoma is a tumor of continuously increasing incidence for which new methods of imaging and targeted therapy are widely sought. Radioiodinated methylene blue is a promising tracer, showing selective uptake in human pigmented melanoma cells. We performed 131I-labeling of the tracer using 1% methylene blue injection U...

journal_title：Anticancer research

authors： Sobal G,Rodrigues M,Sinzinger H

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Nucleotide-binding domain and leucine-rich repeat-containing family, pyrin domain-containing 7 (NLRP7) (pyrin-containing apoptotic protease activating factor-1-like protein 3; PYPAF3, NACHT domain-, leucine-rich repeat, and pyrin domain-containing 7; NALP7) has been thought to contribute to innate immunity a...

journal_title：Anticancer research

authors： Ohno S,Kinoshita T,Ohno Y,Minamoto T,Suzuki N,Inoue M,Suda T

更新日期：2008-07-01 00:00:00

abstract：:A sarcomatoid carcinoma cell line (SAR-HCV) was established from a malignant liver lesion of a patient infected with hepatitis C virus. SAR-HCV cells were successfully xenografted in SCID mice. Vimentin was strongly positive in cultured SAR-HCV cells, the primary tumour lesion and the xenografts. Hepatocyte paraffin 1...

journal_title：Anticancer research

authors： Tai DI,Shen YJ,Weng WH,Chen HW,Kang CC,Chen TC,Liao SK

更新日期：2011-01-01 00:00:00

abstract：:The incidence of breast cancer is increasing rapidly in Taiwan but is still low compared with western countries. The impact of body size factors in western countries inspired us to have a case-control study. A matched case-control study was done on 122 pairs of incident cases of female breast cancer and community cont...

journal_title：Anticancer research

authors： Chie WC,Chen CF,Lee WC,Chen CJ

更新日期：1996-09-01 00:00:00

abstract：BACKGROUND:The nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) pathway is critical in inflammation, proliferation and carcinogenesis. There exist three main players in this pathway. The inhibitor of NF-κB (IκB), IκB kinase (IκK)- NF-κB essential modulator (NEMO) complex and NF-κB. The IkK-NEMO co...

journal_title：Anticancer research

authors： Kadioglu O,Nass J,Saeed ME,Schuler B,Efferth T

更新日期：2015-05-01 00:00:00

abstract：:Chronic treatment with Sasa Health, extract of bamboo grass leaves obtained by alkaline hydrolysis, in drinking water at the concentration of 0.044%-0.088% Fe-Chlorophyllin Na resulted in the significant inhibition of both development and growth of spontaneous mammary tumours in a high mammary tumour strain of SHN vir...

journal_title：Anticancer research

authors： Tsunoda S,Yamamoto K,Sakamoto S,Inoue H,Nagasawa H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Prediction of biological behavior is crucial for selection of new therapeutic modalities in GIST. Here, we aimed to assess whether KIT and PDGFRA mutations have survival impact in gastrointestinal stromal tumors (GIST). PATIENTS AND METHODS:Fifty-five Brazilian patients with completely resected GIST were ex...

journal_title：Anticancer research

authors： Braggio E,Braggio Dde A,Small IA,Lopes LF,Valadão M,Gouveia ME,Moreira Ados S,Linhares E,Romano S,Bacchi CE,Renault IZ,Guimarães DP,Ferreira CG

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The recent availability of a monoclonal antibody against human telomerase reverse transcriptase (hTERT) has enabled us to investigate the telomerase activity of tissue specimens more easily than by classical TRAP assay. In this study, we studied teromerase activity in thyroid tumors using this antibody. MAT...

journal_title：Anticancer research

authors： Ito Y,Yoshida H,Tomoda C,Uruno T,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Kuma K,Miyauchi A

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Epithelioid haemangioendothelioma (EHE) is a rare vascular tumour, which can arise at any site. There is little published data about the management of these tumours. PATIENTS AND METHODS:A retrospective review of patients with histologically-proven EHE presenting to the Royal Marsden Hospital from January 1...

journal_title：Anticancer research

authors： Yousaf N,Maruzzo M,Judson I,Al-Muderis O,Fisher C,Benson C

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND/AIM:Few data are available on the utility of definitive radiation therapy (RT) for pediatric craniopharyngioma. This study sought to evaluate practice patterns and patient outcomes using the Surveillance Epidemiology and End Results database from 2004-2014. MATERIALS AND METHODS:Overall survival (OS) was co...

journal_title：Anticancer research

authors： Hill TK,Baine MJ,Verma V,Alam M,Lyden ER,Lin C,Connolly EP,Zhang C

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Dehydroepiandrosterone (DHEA) and its analogs have potent chemoprotective actions in mouse skin tumorigenesis models. To assess this association in humans, we investigated the relationship of prediagnostic serum concentrations of DHEA and dehydroepiandrosterone sulfate (DHEAS) to the subsequent risk of devel...

journal_title：Anticancer research

authors： Alberg AJ,Gordon GB,Genkinger JM,Hoffman SC,Selvin E,Comstock GW,Helzlsouer KJ

更新日期：2001-11-01 00:00:00

abstract：:Caspase-3 is a key executioner cysteine protease involved in programmed cell death or apoptosis. A ribozyme to human caspase-3 was designed, tested by in vitro cleavage, and transfected into a drug-resistant variant (DLKP-A5F) of a human lung carcinoma cell line (DLKP). By both stable and transient transfection, this ...

journal_title：Anticancer research

authors： Cronin D,Daly C,O'Doherty T,Heenan M,Scanlon KJ,Clynes M

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND/AIM:No standard treatment has been established for poorly-differentiated neuroendocrine carcinomas (PDNEC). The aim of this study is to evaluate the response to the combination of three drugs. MATERIAL AND METHODS:We reviewed 21 PDNEC patients treated from 2008 to 2013 in two Institutions. Five patients wer...

journal_title：Anticancer research

authors： Bajetta E,Catena L,Biondani P,Pusceddu S,Valente M,Bianco N,Novelli E

更新日期：2014-10-01 00:00:00

abstract：:Radiation therapy plays a critical role in women with advanced-stage cervical cancer worldwide, particularly in developing countries, and most of the time it may be the only available treatment. The efficacy of radiation largely depends on the radiosensitivity of the tumor. The high radiation dose associated with ther...

journal_title：Anticancer research

authors： Qin C,Chen X,Bai Q,Davis MR,Fang Y

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Certain viruses, notably human papillomavirus (HPV), cytomegalovirus (CMV), herpes simplex virus (HSV) and Epstein-Barr virus (EBV), are known to produce tumors in animals and cell transformation in vitro and they have been implicated in the pathogenesis of human cancers. All these viruses are also known to ...

journal_title：Anticancer research

authors： Chang F,Syrjänen S,Shen Q,Cintorino M,Santopietro R,Tosi P,Syrjänen K

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND:The effects of resveratrol (a natural polyphenol) on angiogenesis in rat gliomas were investigated by color Doppler ultrasound (CDUS). The correlation among the tumor growth rate, macroscopic angiogenesis measured by CDUS and microscopic angiogenesis was assessed by immunohistochemical staining. MATERIALS A...

journal_title：Anticancer research

authors： Chen JC,Chen Y,Lin JH,Wu JM,Tseng SH

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND/AIM:Epidermal growth factor receptor (EGFR) mutation testing is standard-of-care for advanced non-small cell lung cancer (NSCLC). Outcomes of second-/third-line compared to first-line tyrosine kinase inhibitors (TKIs) have shown conflicting results. We investigated utilization of molecular diagnostics and th...

journal_title：Anticancer research

authors： Sluga R,VAN DEN Borne BEEM,Roepman P,Peters BJM,Kastelijn EA,Schramel FMNH

更新日期：2018-01-01 00:00:00

abstract：:Inv(3)(q21q26)/t(3;3)(q21;q26) is a feature of a distinctive entity of acute myeloid leukemia (AML) associated with normal or elevated platelet count, atypical megakaryocytes and multilineage dysplasia in the bone marrow, as well as minimal to no response to chemotherapy and poor clinical outcome. The presence of an i...

journal_title：Anticancer research

authors： De Braekeleer E,Douet-Guilbert N,Le Bris MJ,Ianotto JC,Berthou C,Gueganic N,Bovo C,Basinko A,Morel F,De Braekeleer M

更新日期：2013-02-01 00:00:00

abstract：:Development of an effective therapeutic strategy for refractory pancreatic cancer must consider whether chemosensitivity can be induced in chemoresistant cells. We established a pancreatic cancer stem cell-rich cell line using TIG-1 feeder cells and leukemia inhibitory factor (LIF)-rich SNL76/7 conditioned medium. We ...

journal_title：Anticancer research

authors： Imaizumi A,Onishi H,Yamasaki A,Kawamoto M,Umebayashi M,Morisaki T,Hasumi K

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND/AIM:To evaluate the impact of DEPDC1 expression on patient prognosis after hepatic resection for hepatocellular carcinoma (HCC). PATIENTS AND METHODS:We reviewed data from 75 patients who underwent hepatic resection for HCC between 2004 and 2013. Recurrence at 2 years following resection, which mainly inclu...

journal_title：Anticancer research

authors： Amisaki M,Yagyu T,Uchinaka EI,Morimoto M,Hanaki T,Watanabe J,Tokuyasu N,Sakamoto T,Honjo S,Fujiwara Y

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Prolonged exposure to asbestos, a potent carcinogen, has been the generally accepted factor responsible for the development of human mesotheliomas. Recent reports documenting the detection of SV40 DNA in human mesotheliomas suggest the possibility that this known tumor virus may be an additional factor invol...

journal_title：Anticancer research

authors： Arrington AS,Lednicky JA,Butel JS

更新日期：2000-03-01 00:00:00

abstract：:Glucose consumption and tritiated thymidine incorporation were monitored for 54 days in histocultured human superficial transitional cell carcinoma of the bladder, indicating that long-term histoculture of human transitional cell carcinoma of the bladder is feasible. The glucose-consumption rate was relatively similar...

journal_title：Anticancer research

authors： Chang SG,Lee JH,Hong DH,Lee HL,Chai SE,Hoffman RM

更新日期：1994-01-01 00:00:00

abstract：:Antisense inhibition of the RelA subunit but not the NFKB1 subunit of NK-kappa B transcription factor results in a block of cellular adhesion and inhibition of tumor cell growth in vitro and in vivo. Studies aimed at dissecting the molecular mechanism of antisense relA action led to our identification of a kappa B-lik...

journal_title：Anticancer research

authors： Sharma HW,Higgins-Sochaski K,Perez JR,Narayanan R

更新日期：1995-09-01 00:00:00

abstract：:The belief that n-3 polyunsaturated fatty acids are in general cytotoxic to tumor cells appears not to be accurate. Of four tumor cell lines exposed to 35 microM docosahexaenoic acid (DHA, 22:6 n-3), we found only one (A-427, lung carcinoma) to be sensitive, whereas three (A-172, A549 and SK-LU-1) in fact were stimula...

journal_title：Anticancer research

authors： Schønberg SA,Skorpen F

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND/AIM:Cancer incidence and mortalities are growing worldwide, therefore research and development of more effective and less invasive treatments, such as photodynamic therapy, are needed. Herein, we investigated the methylene blue (MB) photoactivation effects in lung epithelial cells (BEAS-2B) and lung adenocar...

journal_title：Anticancer research

authors： Rodríguez-Córdova RJ,Gutiérrez-Valenzuela CA,Bojang P,Esquivel R,Hernández P,Ramos KS,Guzmán-Zamudio R,Lucero-Acuña A

更新日期：2019-07-01 00:00:00