Abstract:
:A 34-year-old man with cystic fibrosis (CF) sustained a bilateral fractured neck of the femur during the course of six grand mal seizures. The fractures were successfully treated with bipolar hemi-arthroplasties. Several risk factors for osteoporosis were present. Bone pathology showed reduced femoral head bone density. Osteoporosis of the lumbar spine was confirmed by dual-energy X-ray absorptiometry. As the life expectancy of patients with CF continues to improve, osteoporosis and its sequelae will become more common. We should be aware of the increased risk of bilateral fractured neck of the femur following epileptic seizure in CF.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Lim AY,Isopescu S,Thickett KM,Gumery LB,Darby AJ,Honeybourne D,Stableforth DEdoi
10.1016/s0953-6205(03)00036-0subject
Has Abstractpub_date
2003-05-01 00:00:00pages
196-198issue
3eissn
0953-6205issn
1879-0828pii
S0953620503000360journal_volume
14pub_type
杂志文章abstract:INTRODUCTION:Patients with chronic hepatitis C (CHC) and end-stage renal disease (ESRD) on dialysis are difficult to treat and show higher dropout rates during treatment. The aim of this study was to analyze the treatment outcomes in patients with CHC and underlying end-stage renal disease on dialysis in Korea. METHOD...
journal_title:European journal of internal medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejim.2015.03.011
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:The role of thrombophilic and cardiovascular risk factors in different manifestations of retinal vein occlusion (RVO), i.e., central or branch RVO, and at different ages is still debated. AIMS:To evaluate the association between thrombophilic and cardiovascular risk factors and the risk of RVO (overall, sep...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2017.06.022
更新日期:2017-10-01 00:00:00
abstract::Early repolarization syndrome (ERS) is characterized by the presence, in most cases in mid-to-lateral precordial leads, of a J wave on the downsloping portion of the QRS complex, followed by an elevation of the ST-segment with upward concavity. ERS is considered a benign electrocardiographic pattern of ventricular rep...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2007.06.013
更新日期:2008-06-01 00:00:00
abstract::Monoclonal gammopathy of unknown significance (MGUS) is the most frequent plasma cell disorder that commonly affects elderly patients. Although it is an asymptomatic condition, as well as smoldering myeloma (SMM), the risk of progression to multiple myeloma requiring therapy or other B-cell disorders varies greatly fo...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2018.05.029
更新日期:2018-12-01 00:00:00
abstract::Atypical hemolytic uremic syndrome (aHUS) is a devastating form of renal thrombotic microangiopathy. In the last five years, we have finally witnessed a dramatic improvement in the management of aHUS patients, and three breakthroughs in our understanding of aHUS have led to such an improvement. The first breakthrough ...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2013.05.008
更新日期:2013-09-01 00:00:00
abstract::Sickle-cell trait has been characterized as a benign condition. However, life-threatening complications sometimes develop. Acute chest syndrome (ACS) is usually described in homozygous sickle cell disease, but it rarely develops in individuals with sickle-cell trait. Two cases of ACS in patients with sickle-cell trait...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2004.03.010
更新日期:2004-07-01 00:00:00
abstract::The rising number of clinical guidelines poses a new challenge to the internists. The main problems are: 1) available documents suffer from heterogeneous methodological quality, and 2) most of clinical guidelines target an 'ideal' patient affected by a single condition, while in real practice internists must face with...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2020.05.016
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:To describe the clinical characteristics and evolution of a series of adult patients hospitalized for neuro-Behçet disease (NBD). METHODS:Consecutive patients admitted for NBD in a teaching hospital were retrospectively selected. Disability at discharge and during follow-up was graded with the modified Rank...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2010.08.003
更新日期:2010-12-01 00:00:00
abstract::Biologics embrace a wide range of substances synthesized by cells or living organisms by means of different biological processes, including recombinant DNA technology, controlled gene expression, or antibody technologies. A biosimilar establishes similarity to the reference medicinal product in terms of quality charac...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2016.06.005
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Many activities contribute to reduce drug-related problems. Among them, the medication reconciliation (MR) is used to compare the best possible medication history (BPMH) and the current admission medication order (AMO) to identify and solve unintended medication discrepancies (UMD). This study aims to assess...
journal_title:European journal of internal medicine
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejim.2014.09.012
更新日期:2014-11-01 00:00:00
abstract:SUMMARY:The aims of this study were to determine the incidence of fungal infections in hospital intensive care units and to evaluate a molecular method to detect these infections. MATERIAL AND METHODS:The participants in this study were patients admitted to any of the 10 intensive care units at Nemazi Hospital (Shiraz...
journal_title:European journal of internal medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejim.2011.08.025
更新日期:2011-12-01 00:00:00
abstract::The purpose of this study is to determine the relationship between heat stroke and ischemic heart disease (IHD), in a nationwide population using a longitudinal approach. We retrospectively examined the data from the National Health Insurance Research Database (NHIRD) in Taiwan, for patients examined between 2000 and ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2018.09.019
更新日期:2019-01-01 00:00:00
abstract::The atherothrombotic conditions, coronary artery disease, cerebrovascular disease and peripheral arterial disease (PAD), together account for almost one-half of all deaths in Europe each year; however, perception of the specific risks associated with PAD is generally poor compared with its related conditions. PAD is n...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2008.09.013
更新日期:2009-03-01 00:00:00
abstract:OBJECTIVE:In a previous study involving 18 hypertensive patients with type 2 diabetes mellitus, we found that replacement of valsartan and candesartan by telmisartan significantly improved insulin sensitivity and significantly increased serum adiponectin levels in the patients. We investigated the effects of 3 angioten...
journal_title:European journal of internal medicine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ejim.2010.01.014
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Iron deficiency anaemia is associated with gastrointestinal (GI) malignancy and is an indication for GI investigations. However, the relevance of iron deficiency without anaemia (IDWA) and the underlying risks of GI malignancy are uncertain. Therefore, the aim of this study was to estimate the prevalence of ...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2019.12.015
更新日期:2020-02-01 00:00:00
abstract::Background: Ghrelin causes weight gain by increasing food intake in rodents. Tumor necrosis factor alpha (TNFalpha) is produced by adipose tissue, modulates its metabolism and stimulates catabolic processes. The aim of our study was to evaluate whether weight loss treatment modulates serum concentrations of TNFalpha a...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2004.02.002
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Non-Invasive Ventilation (NIV) represents a standard of care to treat some acute respiratory failure (ARF). Data on its use in pneumonia are lacking, especially in a setting outside the Intensive Care Unit (ICU). The aims of this study were to evaluate the use of NIV in ARF due to pneumonia out...
journal_title:European journal of internal medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejim.2018.09.025
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND & AIMS:Recently we have shown that cartilage oligomeric matrix protein (COMP), a fibrillar collagen assembly regulator, is strongly associated with cirrhosis and hepatocellular carcinoma progression. Therefore, we assessed whether serum COMP levels can be used as a non-invasive fibrosis marker in patients wi...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2017.01.007
更新日期:2017-03-01 00:00:00
abstract::Pattern recognition of the long-term disease course before, during, and after pregnancy can provide us with data about the influence of pregnancy on IBD, and vice versa. Determinants that predict an indolent versus an aggressive disease course are currently being sought. Our intention is to analyze the disease course ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/s0953-6205(00)00088-1
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Knowing what substances cause death in intoxicated patients is of medical, legal, and political relevance. Harmonized data documentation like TESS (Toxic Exposure Surveillance System) in the United States does not exist yet in Germany. However, the GIZ-Nord Poison Center in Göttingen issues an annual report ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2006.04.009
更新日期:2006-11-01 00:00:00
abstract::In all industrialized countries, life expectancy has risen in the past 100 years. The incidence of elderly patients reaching end-stage renal disease (ESRD) and requiring renal replacement therapy has also increased. During the past few decades, the pattern of ESRD has changed significantly with the emerging predominan...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/s0953-6205(01)00121-2
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:While the promotion of health-related fitness is thereby widespread, less focus is currently being given on the biological influence that physical activity might exert on results of laboratory testing. As such, this study was undertaken to assess the kinetics of liver injury markers following physical exerci...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2011.02.007
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:In the era of the World Wide Web we sought to examine whether the use of PubMed and Google can help physicians to improve their diagnostic skills. METHODS:Twenty-six diagnostic cases presented in the case records of the New England Journal of Medicine during 2005 were used for our analysis. Three investigat...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2009.07.014
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Arterial stiffness has recently been proposed as a powerful independent predictor of cardiovascular disease. However, the influence of arterial stiffening on the interaction between the heart and large vessels and atherosclerosis is not well defined. The arterial stiffness index (ASI) has recently been deter...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2005.06.011
更新日期:2005-12-01 00:00:00
abstract::Stroke is a leading cause of death worldwide and the first cause of disability in the Western world. Over the last 20 years, antiplatelet agents have reduced overall stroke rates in primary and secondary prevention in men. However, this has not been the case for women. In this narrative review, the most widely used an...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2012.04.010
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND AND AIM:Chronic kidney disease (CKD) and cardiovascular disease are closely interrelated and the presence of one condition synergistically affects the prognosis of the other, in a negative manner. There are surprisingly very few data on the relationship between baseline coronary artery disease (CAD) severity...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2016.06.031
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:To describe trends in the rates and short-term outcomes of renal transplants (RTx) among patients with or without diabetes in Spain (2002-2013). METHODS:We used national hospital discharge data to select all hospital admissions for RTx. We divided the study period into four three-year periods. Rates were ca...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2016.07.031
更新日期:2017-01-01 00:00:00
abstract::Type IV Ehlers-Danlos syndrome (EDS) is the only lethal form of EDS, mostly due to vascular complications. We describe a patient suffering from EDS type IV who presented with right thromboembolic renal infarctions due to a right renal artery aneurysm. We preferred observation to anticoagulation therapy because the thr...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2006.02.008
更新日期:2006-08-01 00:00:00
abstract::A 59 year old lady had just completed renal dialysis via a central venous catheter when she developed severe chest pain. She subsequently has severe haematemesis and emergency endoscopy showed a lesion in her esophagus consistent with the tip of her venous catheter, and extensive bleeding from the lesion. A chest X-ra...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2007.07.004
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND:The health status of patients with sarcoidosis has rarely been studied, despite the increasing numbers of health-related quality of life publications on other respiratory diseases. The aim of this cross-sectional study was to investigate whether sarcoidosis affects quality of life (QoL), using specifically d...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2006.02.024
更新日期:2006-10-01 00:00:00