abstract：PURPOSE:. The final diagnosis of myocarditis is challenging. The aim of our study was to provide the D.A.M.E. (Diagnosis of Acute Myocarditis in Emergency) Score for the fast identification of patients suffering from myocarditis at Emergency Department (ED). METHODS:. This was a multicenter, retrospective study involv...

journal_title：European journal of internal medicine

authors： Scicchitano P,Grazioli Gauthier L,D'Agostino C,Caldarola P,Solarino B,Massari F,Chiarella F,Sinagra G,Manca F,Ciccone MM

更新日期：2021-01-24 00:00:00

abstract：BACKGROUND:Few data are available on the validity of "Sepsis-3" criteria in identifying patients with sepsis in internal medicine wards (IMWs). Real-life data about this topic and on the prevalence of sepsis in IMWs could be useful for improving hospital organization. OBJECTIVES:To assess the validity of "Sepsis-3" cr...

journal_title：European journal of internal medicine

authors： Fortini A,Faraone A,Meini S,Bettucchi M,Longo B,Valoriani B,Forni S,Italian Federation of Hospital Internists (FADOI) - Sepsis Collaboration Group of the Tuscany Region.

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:Antithrombotic/anticoagulation effects of direct oral anticoagulants (DOACs) are dose-dependent. However, recent observations suggest that administering lower dose DOACs may better protect against all-cause mortality. We investigated whether, in patients with established atherosclerosis, DOAC dose selection ...

journal_title：European journal of internal medicine

authors： Cappato R,Chiarito M,Giustozzi M,Briani M,Ali H,Riva L,Bonitta G,Lodigiani C,Furlanello F,Balla C,Lupo P,Stefanini G

更新日期：2021-01-01 00:00:00

abstract：STUDY OBJECTIVE:Early risk stratification of septic patients presenting to the emergency department (ED) is challenging. The aim of the study was to evaluate the prognostic role of plasmatic sodium level (PNa+) derangements at ED presentation in septic patients. METHODS:According to PNa+ at ED presentation patients we...

journal_title：European journal of internal medicine

authors： Castello LM,Gavelli F,Baldrighi M,Salmi L,Mearelli F,Fiotti N,Patrucco F,Bellan M,Sainaghi PP,Ronzoni G,Di Somma S,Lupia E,Muiesan ML,Biolo G,Avanzi GC

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Tachycardia is a reliable predictor of adverse outcomes in normotensive patients with acute pulmonary embolism (PE). However, different prognostic relevant heart rate thresholds have been proposed. The aim of the study was to investigate the prognostic performance of different thresholds used for defining ta...

journal_title：European journal of internal medicine

authors： Hobohm L,Becattini C,Ebner M,Lerchbaumer MH,Casazza F,Hasenfuß G,Konstantinides SV,Lankeit M

更新日期：2020-12-01 00:00:00

abstract：:The International Society of Hypertension (ISH) has recently developed practice guidelines for the management of hypertension in adults aged ≥18 years. Conceptually, the 2020 ISH Guidelines are closer to the 2018 ESC/ESH Guidelines rather than to the 2017 ACC/AHA Guidelines. The ISH Guidelines have two distinctive fea...

journal_title：European journal of internal medicine

authors： Verdecchia P,Reboldi G,Angeli F

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Rheumatoid arthritis (RA) patients have high risk of heart failure (HF). AIMS:Identifying the risk factors and mechanistic pathways associated with HF in patients with RA. METHODS:Cohort study enrolling 355 RA patients. HF was defined according to the ESC criteria. 93 circulating protein-biomarkers (91CVDI...

journal_title：European journal of internal medicine

authors： Ferreira MB,Fonseca T,Costa R,Marinhoc A,Carvalho HC,Oliveira JC,Zannad F,Rossignol P,Gottenberg JE,Saraiva FA,Rodrigues P,Barros AS,Ferreira JP

更新日期：2020-11-06 00:00:00

abstract：:The management of arterial hypertension is very challenging in everyday clinical practice. Blood pressure control rates remain disappointingly low, despite intense efforts. Poor adherence to antihypertensive treatment is among the main causes of inadequate blood pressure control. Among the various parameters leading t...

journal_title：European journal of internal medicine

authors： Manolis A,Doumas M,Ferri C,Mancia G

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Scores for risk prediction used in immunocompetent patients with sepsis or pneumonia are poorly evaluated in immunocompromised patients. Therefore, we evaluated the prognostic value of the qSOFA- and CRB-65-criteria in immunocompromised patients presenting with pneumonia. METHODS:Retrospective cohort study ...

journal_title：European journal of internal medicine

authors： Frantz S,Schulte-Hubbert B,Halank M,Koschel D,Kolditz M

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is independently associated with increased morbidity and mortality. Quality improvement has been identified as an important goal in the care of patients with AKI. Different settings can be targeted to improve AKI care, broadly classified these include the inpatient and outpatient en...

journal_title：European journal of internal medicine

authors： Macedo E,Bihorac A,Siew ED,Palevsky PM,Kellum JA,Ronco C,Mehta RL,Rosner MH,Haase M,Kashani KB,Barreto EF

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVE:To investigate the association between body mass index (BMI) and oral anticoagulant (OAC) prescription in atrial fibrillation (AF). METHODS:Patients with newly diagnosed non-valvular AF (<3 months) with ≥1 stroke risk factors enrolled in the Global Registry on Long-Term Oral Antithrombotic Treatment in Patie...

journal_title：European journal of internal medicine

authors： Boriani G,Huisman MV,Teutsch C,Marler S,França LR,Lu S,Lip GYH,GLORIA-AF Investigators.

更新日期：2020-10-01 00:00:00

abstract：:The SARS-CoV-2 epidemic, which has spread to many countries around the world, has hit Europe particularly hard. From our point of view, in a rural emergency department (with an annual patient census of around 25,000) in northeastern Italy, it is necessary to preserve the hospital and prevent it from becoming an outbre...

journal_title：European journal of internal medicine

authors： Copetti R,Amore G,Di Gioia CC,Orso D

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:For nonneoplastic neurological diseases, no recommendation exists regarding the place or appropriate timing of brain biopsy. The aim of this study was to evaluate the diagnostic yield and safety of brain biopsies from patients with neurological diseases of unknown etiology. METHODS:We performed a retrospect...

journal_title：European journal of internal medicine

authors： Mathon B,Le Joncour A,Bielle F,Mokhtari K,Boch AL,Peyre M,Amoura Z,Cacoub P,Younan N,Demeret S,Shotar E,Burrel S,Fekkar A,Robert J,Amelot A,Pineton de Chambrun M,PSL BRAIN-BIOPSY STUDY GROUP.

更新日期：2020-10-01 00:00:00

abstract：:Cough, a defense mechanism for clearing the airways of secretions, exudate, or foreign bodies, may become a troublesome symptom. Chronic cough, one of the most frequent symptoms requiring medical attention, is often not due to identifiable causes in adults. Chronic productive cough defines chronic bronchitis, and thus...

journal_title：European journal of internal medicine

authors： Spanevello A,Beghé B,Visca D,Fabbri LM,Papi A

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Anticholinergic drugs may increase the risk of delirium in non-critically ill patients, but it is unclear whether exposure to these drugs is also a risk factor for Intensive Care Unit (ICU) delirium. In this study the hypothesis was tested that anticholinergic drug exposure at ICU admission increases the ris...

journal_title：European journal of internal medicine

authors： Vondeling AM,Knol W,Egberts TCG,Slooter AJC

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Bleeding assessment tools (BATs) have been developed to quantify bleeding severity. Their ability to predict for the diagnosis of a bleeding disorder has not been thoroughly investigated. OBJECTIVES:To evaluate the ability of the Vicenza BAT and the ISTH BAT to distinguish patients with an established bleed...

journal_title：European journal of internal medicine

authors： Gebhart J,Hofer S,Kaider A,Rejtö J,Ay C,Pabinger I

更新日期：2020-08-01 00:00:00

abstract：:The rising number of clinical guidelines poses a new challenge to the internists. The main problems are: 1) available documents suffer from heterogeneous methodological quality, and 2) most of clinical guidelines target an 'ideal' patient affected by a single condition, while in real practice internists must face with...

journal_title：European journal of internal medicine

authors： Leśniak W,Morbidoni L,Dicker D,Marín-León I,EFIM.

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:An abnormal ankle-brachial pressure index (ABI) is a marker of the risk for increased total and cardiovascular (CV) mortality. However, it is not clear whether it is associated with an even worse prognosis in patients with previous CV events or with cancer mortality. MATERIALS AND METHODS:Consecutive subjec...

journal_title：European journal of internal medicine

authors： Visonà A,De Paoli A,Fedeli U,Tonello D,Zalunardo B,Zanatta N,Martini R,Pesavento R,Cuppini S,Prior M,Benazzi S,Cimminiello C,Avossa F

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a serious complication in patients hospitalized for decompensated heart failure (HF). Currently, AKI definitions consider creatinine levels at admission as reference of baseline renal function (RF). However, renal impairment may already be present at admission. We aimed to study ...

journal_title：European journal of internal medicine

authors： Sanchez-Serna J,Hernandez-Vicente A,Garrido-Bravo IP,Pastor-Perez F,Noguera-Velasco JA,Casas-Pina T,Rodriguez-Serrano AI,Núñez J,Pascual-Figal D

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Tocilizumab, a humanized monoclonal antibody, targets IL-6 receptors blocking downstream pro-inflammatory effects of IL-6. In preliminary reports it was suggested to be beneficial in patients with severe COVID-19. METHODS:In this open-label prospective study we describe clinical characteristics and outcome ...

journal_title：European journal of internal medicine

authors： Morena V,Milazzo L,Oreni L,Bestetti G,Fossali T,Bassoli C,Torre A,Cossu MV,Minari C,Ballone E,Perotti A,Mileto D,Niero F,Merli S,Foschi A,Vimercati S,Rizzardini G,Sollima S,Bradanini L,Galimberti L,Colombo R,Mic

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Pneumonia with respiratory failure represents the main cause of death in COVID-19, where hyper inflammation plays an important role in lung damage. This study aims to evaluate if tocilizumab, an anti-soluble IL-6 receptor monoclonal antibody, reduces patients' mortality. METHODS:85 consecutive patients admi...

journal_title：European journal of internal medicine

authors： Capra R,De Rossi N,Mattioli F,Romanelli G,Scarpazza C,Sormani MP,Cossi S

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:inferior vena cava filters (IVCF) are widely used to prevent thromboembolic events in patients not suitable for anticoagulation (AC). Although new generations of filters are optional and therefore retrievable, most of them become permanent. Aim of our study was to evaluate real life IVCF management in a tert...

journal_title：European journal of internal medicine

authors： Buso G,Alatri A,Calanca L,Fresa M,Qanadli SD,Pesavento R,Mazzolai L

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:chronic viral infections by both HCV and HIV may lead to polyclonal activation of B cells resulting in hypergammaglobulinemia. This study retrospectively analyzed the effect of HCV eradication with interferon-free direct-acting antiviral agents (DAAs) on the gamma globulin levels in HCV-infected patients wit...

journal_title：European journal of internal medicine

authors： Milazzo L,van den Bogaart L,Sollima S,Oreni L,Lai A,Morena V,Bonazzetti C,Ridolfo Anna L,Antinori S

更新日期：2020-05-01 00:00:00

abstract：:Vasculitis is characterized by inflammation of the vascular wall. It reaches vessels of different sizes and locations, conditioning multisystem and complex manifestations that require a holistic approach. Antineutrophil cytoplasmic antibody-associated vasculitis has an annual incidence rate of 20 per million inhabitan...

journal_title：European journal of internal medicine

authors： Salvador F

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:Left ventricular (LV) dysfunction is a predictor of mortality in patients with sepsis. However, whether the adverse impact of LV dysfunction depends on fluid balance remains unclear. We retrospectively investigated the impact of LV dysfunction and fluid balance on various outcomes of patients with sepsis. ME...

journal_title：European journal of internal medicine

authors： Hong JY,Shin J,Kim WY

更新日期：2020-04-01 00:00:00

abstract：BACKGROUNDS:The prognosis and management of left ventricular thrombus (LVT) following acute myocardial infarction (AMI) have not been well evaluated since the advent of primary percutaneous coronary intervention (PCI). We therefore conducted a meta-analysis to assess the prognostic effect of LVT after AMI in primary PC...

journal_title：European journal of internal medicine

authors： Chen PF,Tang L,Yi JL,Pei JY,Hu XQ

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Iron deficiency anaemia is associated with gastrointestinal (GI) malignancy and is an indication for GI investigations. However, the relevance of iron deficiency without anaemia (IDWA) and the underlying risks of GI malignancy are uncertain. Therefore, the aim of this study was to estimate the prevalence of ...

journal_title：European journal of internal medicine

authors： Alexandre L,Manning C,Chan SSM

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Hyperuricemia prognostic impact on clinical outcomes in chronic heart failure (HF) patients has been investigated with inconclusive results. OBJECTIVES:Aim of the study was to evaluate the prognostic impact of serum uric acid (SUA) on long-term clinical outcomes in HF. METHODS:An analysis of MECKI (Metabol...

journal_title：European journal of internal medicine

authors： Piepoli MF,Salvioni E,Corrà U,Doni F,Bonomi A,La Gioia R,Limongelli G,Paolillo S,Sinagra G,Scardovi AB,Raimondo R,Emdin M,Re F,Cicoira M,Correale M,Badagliacca R,Clemenza F,Lombardi C,Agostoni P

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:Although tramadol and codeine occasionally have been reported to cause hyponatremia the evidence is scarce. The objective of this investigation was to study the association between weak opioids (tramadol and codeine) and hospitalization due to hyponatremia. METHODS:This was a register-based case-control stu...

journal_title：European journal of internal medicine

authors： Falhammar H,Calissendorff J,Skov J,Nathanson D,Lindh JD,Mannheimer B

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The value of salivary cortisol measurement to study stress-related adrenal response is controversial. The study aim was to assess the role of salivary cortisol measurement to detect time-related changes of adrenal response in critically ill patients. PATIENTS AND METHODS:Patients with organ failure, sepsis ...

journal_title：European journal of internal medicine

authors： Puglisi S,Pizzuto A,Laface B,Panero F,Aprà F,Palmas E,Perotti P,Reimondo G,Boccuzzi A,Terzolo M

更新日期：2019-10-01 00:00:00

abstract：INTRODUCTION:Rituximab induced serum sickness (RISS) is a rare delayed hypersensitivity reaction. The aim of this study was to describe the epidemiological and clinical characteristics of the RISS cases reported in France. METHOD:Serum sickness cases involving rituximab were identified from the French PharmacoVigilanc...

journal_title：European journal of internal medicine

authors： Bayer G,Agier MS,Lioger B,Lepelley M,Zenut M,Lanoue MC,Maillot F,Jonville-Bera AP

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Porphyrias are a group of metabolic diseases, individually rare but with an important combined prevalence. Because of their pathological complexity and clinical heterogeneity, they present a challenging diagnosis. The present review aims to provide a clinically based approach to the recognition and treatment...

journal_title：European journal of internal medicine

authors： Rigor J,Pinto SA,Martins-Mendes D

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND:Poisoned patients are frequently admitted following Emergency Department (ED) presentation, while the necessity of such admissions is hardly investigated. We determined the proportion and characteristics of poisoned patients who were admitted, but in retrospect had an uneventful admission. METHODS:For this ...

journal_title：European journal of internal medicine

authors： Hondebrink L,Rietjens SJ,Donker DW,Hunault CC,van den Hengel-Koot I,Verputten PM,de Vries I,Kaasjager KAH,Dekker D,de Lange DW

更新日期：2019-08-01 00:00:00

abstract：:IgG4-related disease (IgG4-RD) is an autoimmune disorder characterized by substantial infiltration of plasma cells with IgG4 in target organs. Lung manifestations predominantly present as inflammatory pseudotumor, interstitial pneumonitis, organizing pneumonia, and lymphomatoid granulomatosis. There is no specific dia...

journal_title：European journal of internal medicine

authors： Morales AT,Cignarella AG,Jabeen IS,Barkin JS,Mirsaeidi M

更新日期：2019-08-01 00:00:00

abstract：AIMS:To validate externally the CACE-HF clinical prediction rule, which predicts 1-year mortality in patients with heart failure (HF). METHODS:We performed an external validation of the CACE-HF risk score in patients included in the RICA heart failure registry who had completed 1 year of follow-up, comparing the chara...

journal_title：European journal of internal medicine

authors： Quirós-López R,Manzano-Espinosa L,Bilbao A,Montero Pérez-Barquero M,Cepeda-Rodrigo JM,Escobar-Martínez A

更新日期：2019-08-01 00:00:00

abstract：:The Medical Emergency Team (MET) has enhanced the recognition and response to clinical deterioration in acute healthcare. However, patients reviewed by the MET are at increased risk of in-hospital death. Identifying patients at risk of deterioration may improve patient outcomes. AIM: To identify patient demographic, m...

journal_title：European journal of internal medicine

authors： Allen J,Orellana L,Jones D,Considine J,Currey J

更新日期：2019-08-01 00:00:00

abstract：:Tick-borne encephalitis (TBE) is an emerging health threat that is spreading in many parts of Europe. The mix of socio-economical, ecological and climatic factors as well as the presence of more susceptible hosts is actively contributing to the increasing number of TBE reported cases. TBE is an important cause of cent...

journal_title：European journal of internal medicine

authors： Riccardi N,Antonello RM,Luzzati R,Zajkowska J,Di Bella S,Giacobbe DR

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The Charlson's is the most used comorbidity index. It comprises 19 comorbidities, some of which are infrequent in elderly patients with acute coronary syndrome (ACS), while some others are manifestations of cardiac disease rather than comorbidities. Our goal was to simplify comorbidity assessment in elderly ...

journal_title：European journal of internal medicine

authors： Sanchis J,Soler M,Núñez J,Ruiz V,Bonanad C,Formiga F,Valero E,Martínez-Sellés M,Marín F,Ruescas A,García-Blas S,Miñana G,Abu-Assi E,Bueno H,Ariza-Solé A

更新日期：2019-04-01 00:00:00

abstract：:The purpose of this study is to determine the relationship between heat stroke and ischemic heart disease (IHD), in a nationwide population using a longitudinal approach. We retrospectively examined the data from the National Health Insurance Research Database (NHIRD) in Taiwan, for patients examined between 2000 and ...

journal_title：European journal of internal medicine

authors： Tseng MF,Chou CL,Chung CH,Chien WC,Chen YK,Yang HC,Chu P

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Non-Invasive Ventilation (NIV) represents a standard of care to treat some acute respiratory failure (ARF). Data on its use in pneumonia are lacking, especially in a setting outside the Intensive Care Unit (ICU). The aims of this study were to evaluate the use of NIV in ARF due to pneumonia out...

journal_title：European journal of internal medicine

authors： Brambilla AM,Prina E,Ferrari G,Bozzano V,Ferrari R,Groff P,Petrelli G,Scala R,Causin F,Noto P,Bresciani E,Voza A,Aliberti S,Cosentini R,3P study group.

更新日期：2019-01-01 00:00:00