Abstract:
:The purpose of this study is to determine the relationship between heat stroke and ischemic heart disease (IHD), in a nationwide population using a longitudinal approach. We retrospectively examined the data from the National Health Insurance Research Database (NHIRD) in Taiwan, for patients examined between 2000 and 2013. In total, 628 patients with a heat stroke episode were enrolled and matched with 1256 patients without any history of a heat stroke episode by propensity score matching at a ratio of 1:2. The mean follow-up years of the heat stroke group was 11.89 years and the mean follow up of the control group was 11.51 years. An association between heat stroke episodes and IHD (log-rank p < .001) was found in a univariate cox regression analysis. After multivariate adjustment, age, comorbidities (hypertension, diabetes, stroke), and lower insurance premiums were associated with IHD events in patients who had a heat stroke. IHD was independently associated with heat stroke following cox multivariate regression analysis and patients with a heat stroke episode had a higher incidence of IHD events compared to those without any heat stroke episode (2598.41/105 person-years vs. 1286.14/105 person-years, adjusted hazard ratio 3.527, 95% CI: 2.078-4.032, p < .001). The onset of IHD in patients who suffered a heat stroke was earlier than in those without a heat stroke episode (2.08 ± 3.45 vs. 3.61 ± 3.25 years, p < .001). In conclusion, clinicians should be aware about evaluating the IHD risk following a heat stroke episode in a patient.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Tseng MF,Chou CL,Chung CH,Chien WC,Chen YK,Yang HC,Chu Pdoi
10.1016/j.ejim.2018.09.019subject
Has Abstractpub_date
2019-01-01 00:00:00pages
97-103eissn
0953-6205issn
1879-0828pii
S0953-6205(18)30387-Xjournal_volume
59pub_type
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