Abstract：
BACKGROUND:We aimed to evaluate the presence of nocturnal hypotension (NHP) in ischemic stroke (IS) survivors using ambulatory blood pressure (BP) monitoring (ABPM). METHODS:We included fifty consecutive patients presenting at our outpatient clinic for review and who had been discharged for IS in the previous six months. 24-h ABPM was performed with Spacelab 90207 monitor. NHP episodes were considered those values on which the mean arterial pressure (MAP)<70mm Hg. Patients were divided into two groups according to the presence or absence of NHP. RESULTS:We studied 31 men and 19 women, mean age 68±11years. Episodes of NHP were observed in 21 patients (42%). There were no significant differences with regard to clinical characteristics between groups. With regard to BP, patients with NHP had significantly lower mean 24-hour BPs, mean daytime BPs and mean nighttime BPs. Dipper pattern occurred more often in patients with NHP, although differences were only statistically significant in the diastolic BP values. Mean office readings were 142±26/77±13mm Hg (149±26 versus 133±20; P=0.06; 82±12 versus 71±12; P=0.008). None of the patients showed office SBP <90mmHg and only four had office DBP <60mmHg. CONCLUSIONS:Episodes of NHP in patients with recent IS are common and difficult to detect with clinical cuff measurements. It is necessary to redefine the target BP levels in secondary stroke prevention, possibly because we are subjecting our patients to increased risk of NHP and cerebral hypoperfusion.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Castilla-Guerra L,Fernández-Moreno Mdel C,Espino-Montoro A,López-Chozas JMdoi
10.1016/j.ejim.2011.03.004subject
Has Abstractpub_date
2011-10-01 00:00:00pages
501-4issue
5eissn
0953-6205issn
1879-0828pii
S0953-6205(11)00060-4journal_volume
22pub_type
杂志文章abstract：:Venous thromboembolism (VTE) is frequent in patients hospitalized in Internal Medicine wards. It carries a considerable morbidity and mortality. Recommendations for use of anticoagulation are graded 1A in leading evidence-based consensus guidelines. Implementation of these guidelines is suboptimal. Lack of awareness s...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2011.11.005
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVE:Left ventricular (LV) dysfunction is a predictor of mortality in patients with sepsis. However, whether the adverse impact of LV dysfunction depends on fluid balance remains unclear. We retrospectively investigated the impact of LV dysfunction and fluid balance on various outcomes of patients with sepsis. ME...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2019.11.019
更新日期：2020-04-01 00:00:00
abstract：:Approximately 30% of patients with chronic HCV infection show persistently normal ALT levels. Although formerly referred to as 'healthy' or 'asymptomatic' HCV carriers, and thus historically excluded from antiviral treatment, it has now become clear that the majority of these patients have some degree of histological ...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2009.12.006
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Heart failure (HF) with reduced ejection fraction remains a major therapeutic challenge. The aim of this study was to investigate the role of novel cardiovascular biomarkers, i.e. soluble suppression of tumorigenicity (sST2), growth-differentiation factor-15 (GDF-15), soluble urokinase plasminogen activator ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2017.05.027
更新日期：2017-10-01 00:00:00
abstract：BACKGROUND:Anemia may have important deleterious effects on patients with heart failure. We investigated the presence and causes of anemia among patients admitted because of new-onset congestive heart failure. The prognostic value of anemia was also evaluated. METHODS:We evaluated the presence of anemia, which was def...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2005.11.015
更新日期：2006-05-01 00:00:00
abstract：:Human serum albumin (HSA) is the most abundant circulating protein and accounts for about 70% of the plasma colloid osmotic pressure. Beside the well known capacity to act as plasma-expander, HSA is provided of many other properties which are unrelated to the regulation of fluid compartmentalization, including binding...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2013.05.015
更新日期：2013-12-01 00:00:00
abstract：:Anthracosis is a form of pneumoconiosis caused by coal dust or by a smoky and polluted environment. Anthracosis often presents in pulmonary form; only rarely are extrathoracic, esophageal, and mediastinal anthracoses documented. We report a rare case of anthracosis with multiple mediastinal lymphadenopathy. ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2003.09.001
更新日期：2003-11-01 00:00:00
abstract：:Background: Cases of lipodystrophy syndrome and metabolic disorders have been described since the onset of highly active antiretroviral therapy in HIV-infected patients. The aim of our study was to estimate the prevalence of lipodystrophy (LD) and to define the associated lipid profile of these patients. Methods: The ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(00)00103-5
更新日期：2000-10-01 00:00:00
abstract：:Microchimerism is defined by the presence within an individual of a low level of cells derived from another individual. Systemic sclerosis is clinically similar to chronic graft-versus-host disease, a known condition of chimerism, which has led some authors to explore the hypothesis that microchimerism may contribute ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(02)00098-5
更新日期：2002-09-01 00:00:00
abstract：BACKGROUND:Tocilizumab, a humanized monoclonal antibody, targets IL-6 receptors blocking downstream pro-inflammatory effects of IL-6. In preliminary reports it was suggested to be beneficial in patients with severe COVID-19. METHODS:In this open-label prospective study we describe clinical characteristics and outcome ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2020.05.011
更新日期：2020-06-01 00:00:00
abstract：:Angiomyolipomas are very common in patients with tuberous sclerosis complex (TSC) and cause substantial morbidity. Until now, arterial embolization has been the recommended treatment for symptomatic patients. We report the case of a woman with TSC and giant angiolipomas in whom sirolimus induced a dramatic reduction i...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.07.017
更新日期：2007-01-01 00:00:00
abstract：BACKGROUND:The objective of this study is to compare the characteristics, outcomes, and clinical complications of patients with pulmonary embolism (PE) who were treated at home as outpatients versus traditional hospitalization. METHODS:Prospective study from January 2006 to June 2007. Selected patients diagnosed at th...
journal_title：European journal of internal medicine
pub_type： 临床试验,杂志文章
doi：10.1016/j.ejim.2009.04.003
更新日期：2009-10-01 00:00:00
abstract：:Rhabdomyolysis is a syndrome of skeletal muscle cell damage that leads to the release of toxic intracellular material into the systemic circulation. The pathogenesis of rhabdomyolysis is based on an increase in free ionized calcium in the cytoplasm. Its main complications include (a) acute renal failure, which is trig...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2007.06.037
更新日期：2008-12-01 00:00:00
abstract：:There is growing evidence suggesting a causative relationship between adrenal adenomas and metabolic and cardiovascular deteriorations. Although demonstrated frequently in subjects with subclinical Cushing Syndrome, subjects with non-functioning adrenal adenomas feature a variety of metabolic and cardiovascular conseq...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2013.02.005
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:There are ethnic differences in the incidence of venous thromboembolism. This is the first nationwide study to examine whether there is an association between country of birth in first-generation immigrants and first hospitalisation for venous thrombosis (VT) and pulmonary embolism (PE), and to study whether...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2011.07.015
更新日期：2012-01-01 00:00:00
abstract：:The morbidity and mortality related to many communicable infectious diseases have significantly decreased in Western countries largely because of the use of antibiotics, and the implementation of well-planned vaccination strategies and national immunisation schedules specifically aimed at infants and children. However...
journal_title：European journal of internal medicine
pub_type： 杂志文章,评审
doi：10.1016/j.ejim.2013.12.004
更新日期：2014-03-01 00:00:00
abstract：:We report a case of Strongyloides stercoralis hyperinfection in a Spanish patient who had never traveled to an endemic area and in whom HIV infection and long-term immunosuppressive treatment most likely contributed to the dissemination of strongyloidiasis. ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2004.10.002
更新日期：2004-12-01 00:00:00
abstract：BACKGROUND:Peripheral arterial disease (PAD) in the aortoiliac segment is found in nearly a half of patients with PAD. The aim of this study was to estimate the influence of obesity and fat distribution on the occurrence of aortoiliac PAD in middle-aged men. METHODS:This case-control study included 204 middle-aged men...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2010.07.019
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:The site of acquisition of infection may have a major impact on outcome. The health care-related (HCR) environment has recently come under scrutiny. In a group of patients with bacteremic septic arthritis (SA), we compared their characteristics, type of SA, microbiology and prognosis according to the site of...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2015.11.013
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Although a decreasing trend of tuberculosis (TB) was reported in Turkey, higher proportion of extrapulmonary tuberculosis (EPT) was revealed. MATERIAL AND METHODS:In this retrospective study, clinical and laboratory data of 141 EPT patients were evaluated for a seven-year period by using descriptive statist...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2013.08.704
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Percutaneous balloon mitral valvuloplasty (PBMV) has become the procedure of choice for isolated, uncomplicated mitral stenosis (MS) with favorable morphology and may be a useful method for surgical high-risk conditions such as advanced age, the presence of severe tricuspid regurgitation, New York Heart Asso...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2005.02.012
更新日期：2005-10-01 00:00:00
abstract：AIM:To describe trends in the incidence and outcomes of community-acquired pneumonia (CAP) hospitalizations in Spain (2004-2013). METHODS:We used national hospital discharge data to select all hospital admissions for CAP as primary diagnosis. We analyzed incidence, Charlson comorbidity index (CCI), diagnostic and ther...
journal_title：European journal of internal medicine
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ejim.2016.12.010
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Low serum levels of alkaline phosphatase (ALP) are a hallmark of hypophosphatasia. However, the clinical significance and the underlying genetics of low ALP in unselected populations are unclear. METHODS:In order to clarify this issue, we performed a clinical, biochemical and genetic study of 42 individuals...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2015.12.019
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:The Simple Clinical Score (SCS) determined at the time of admission places acutely ill general medical patients into one of five risk classes associated with an increasing risk of death within 30 days. The cohort of acute medical patient that the SCS was derived from had, on average, four combinations of 74 ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2008.04.012
更新日期：2009-01-01 00:00:00
abstract：INTRODUCTION:Rituximab induced serum sickness (RISS) is a rare delayed hypersensitivity reaction. The aim of this study was to describe the epidemiological and clinical characteristics of the RISS cases reported in France. METHOD:Serum sickness cases involving rituximab were identified from the French PharmacoVigilanc...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2019.06.009
更新日期：2019-09-01 00:00:00
abstract：:Background: It is unclear whether methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-sensitive S. aureus (MSSA) differ in virulence. We therefore carried out a prospective study of cases of S. aureus bacteremia over a period of 2 years at our university hospital. We report herein the results of a compa...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/s0953-6205(01)00189-3
更新日期：2002-02-01 00:00:00
abstract：BACKGROUND:Many activities contribute to reduce drug-related problems. Among them, the medication reconciliation (MR) is used to compare the best possible medication history (BPMH) and the current admission medication order (AMO) to identify and solve unintended medication discrepancies (UMD). This study aims to assess...
journal_title：European journal of internal medicine
pub_type： 临床试验,杂志文章
doi：10.1016/j.ejim.2014.09.012
更新日期：2014-11-01 00:00:00
abstract：BACKGROUND/OBJECTIVES:There is some evidence to suggest that exercise systolic blood pressure (SBP) may be associated with future risk of stroke in subjects without a history of coronary artery disease (CAD). However, the value of an exaggerated exercise SBP response (EESBPR) for predicting stroke in patients referred ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2014.05.013
更新日期：2014-07-01 00:00:00
abstract：SUMMARY:The aims of this study were to determine the incidence of fungal infections in hospital intensive care units and to evaluate a molecular method to detect these infections. MATERIAL AND METHODS:The participants in this study were patients admitted to any of the 10 intensive care units at Nemazi Hospital (Shiraz...
journal_title：European journal of internal medicine
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ejim.2011.08.025
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Knowing what substances cause death in intoxicated patients is of medical, legal, and political relevance. Harmonized data documentation like TESS (Toxic Exposure Surveillance System) in the United States does not exist yet in Germany. However, the GIZ-Nord Poison Center in Göttingen issues an annual report ...
journal_title：European journal of internal medicine
pub_type： 杂志文章
doi：10.1016/j.ejim.2006.04.009
更新日期：2006-11-01 00:00:00
