What diagnoses may make patients more seriously ill than they first appear? Mortality according to the Simple Clinical Score Risk Class at the time of admission compared to the observed mortality of different ICD9 codes identified on death or discharge.

Abstract:

BACKGROUND:The Simple Clinical Score (SCS) determined at the time of admission places acutely ill general medical patients into one of five risk classes associated with an increasing risk of death within 30 days. The cohort of acute medical patient that the SCS was derived from had, on average, four combinations of 74 groupings of ICD9 codes. This paper reports the ICD9 codes associated with the different SCS risk classes and identifies those ICD9 codes with a greater observed mortality than that of other patients in the same SCS risk class. DESIGN:Observational study. SETTING:A small Irish rural hospital. METHODS:The 30-day mortality rates of the 74 commonest ICD9 groupings coded at the time of discharge of 9214 consecutive acutely ill medical patients were compared with the mortality rates associated with their SCS risk class determined at the time of their admission. RESULTS:There was no difference between the observed and the predicted mortality rates for very low risk patients regardless of ICD9 groupings, even though several of these patients suffered from all but two of the 34 ICD9 code groupings associated with an increased risk of death. Within the remaining four risk classes only 14 ICD9 groupings had an observed mortality greater from that of all other patients in the same SCS risk class. CONCLUSION:The Simple Clinical Score (SCS) determined at the time of admission identifies patients at very low risk of death regardless of what diagnoses are subsequently made during their hospitalisation. Nevertheless, patients with a very low risk of death according to their SCS risk class may still have a life-threatening condition that requires treatment in hospital. For higher risk patients only 14 ICD9 code groupings were associated with an observed mortality greater than that of others in the same SCS risk group.

journal_name

Eur J Intern Med

authors

Kellett J,Deane B

doi

10.1016/j.ejim.2008.04.012

subject

Has Abstract

pub_date

2009-01-01 00:00:00

pages

89-93

issue

1

eissn

0953-6205

issn

1879-0828

pii

S0953-6205(08)00147-7

journal_volume

20

pub_type

杂志文章
  • Non-alcoholic fatty liver disease, metabolic syndrome and patatin-like phospholipase domain-containing protein3 gene variants.

    abstract:BACKGROUND & AIMS:Non-alcoholic fatty liver disease was traditionally interpreted as a condition which may progress to liver-related complications. However, the increased mortality is primarily a result of cardiovascular diseases. It has been suggested that fatty liver can be considered as the hepatic consequence of th...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2014.05.012

    authors: Del Ben M,Polimeni L,Brancorsini M,Di Costanzo A,D'Erasmo L,Baratta F,Loffredo L,Pastori D,Pignatelli P,Violi F,Arca M,Angelico F

    更新日期:2014-07-01 00:00:00

  • Determinants of continuous positive airway pressure compliance in a group of Greek patients with obstructive sleep apnea.

    abstract:OBJECTIVE:The aim of the study was to investigate the patients' characteristics that correlate with greater compliance to CPAP use. METHODS:Patients diagnosed with OSAHS and treated with CPAP, who had at least one follow-up visit in the Sleep Clinic during one year, were included in the study. Demographic data, histor...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2009.07.004

    authors: Amfilochiou A,Tsara V,Kolilekas L,Gizopoulou E,Maniou C,Bouros D,Polychronopoulos V

    更新日期:2009-10-01 00:00:00

  • Diagnostic value of C-reactive protein in exudative pleural effusions.

    abstract::BACKGROUND: Tests able to help in the diagnostic work-up of pleural exudates are needed. C-reactive protein (CRP) may be useful for distinguishing between benign and malignant exudates. METHODS: A total of 123 consecutive patients diagnosed as having exudative pleural effusion (60 associated with malignancy and 63 ben...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/s0953-6205(02)00036-5

    authors: Garcia-Pachon E,Llorca I

    更新日期:2002-06-01 00:00:00

  • Genetics of melatonin receptor type 2 is associated with left ventricular function in hypertensive patients treated according to guidelines.

    abstract:BACKGROUND:Melatonin exerts multiple biological effects with potential impact on human diseases. This is underscored by genetic studies that demonstrated associations between melatonin receptor type 2 gene (MTNR1B) polymorphisms and characteristics of type 2 diabetes. We set out to test the hypothesis whether genetic v...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2013.03.015

    authors: Huber M,Treszl A,Reibis R,Teichmann C,Zergibel I,Bolbrinker J,Scholze J,Wegscheider K,Völler H,Kreutz R

    更新日期:2013-10-01 00:00:00

  • Abnormal ankle-brachial index (ABI) predicts primary and secondary cardiovascular risk and cancer mortality.

    abstract:BACKGROUND:An abnormal ankle-brachial pressure index (ABI) is a marker of the risk for increased total and cardiovascular (CV) mortality. However, it is not clear whether it is associated with an even worse prognosis in patients with previous CV events or with cancer mortality. MATERIALS AND METHODS:Consecutive subjec...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2020.02.033

    authors: Visonà A,De Paoli A,Fedeli U,Tonello D,Zalunardo B,Zanatta N,Martini R,Pesavento R,Cuppini S,Prior M,Benazzi S,Cimminiello C,Avossa F

    更新日期:2020-07-01 00:00:00

  • Incidence, predictors and prognostic value of cranial nerve involvement in patients with tuberculous meningitis: a retrospective evaluation.

    abstract:BACKGROUND:Cranial nerve involvement is commonly observed in patients with tuberculous meningitis. The present study evaluated the incidence, predictors and prognostic significance of cranial nerve involvement in tuberculous meningitis. MATERIALS AND METHOD:One hundred-fifty-eight adult patients with tuberculous menin...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2011.01.007

    authors: Sharma P,Garg RK,Verma R,Singh MK,Shukla R

    更新日期:2011-06-01 00:00:00

  • Different impact of aspirin on renal progression in patients with predialysis advanced chronic kidney disease with or without previous stroke.

    abstract:BACKGROUND:The benefit of reducing the risk of stroke against increasing the risk of renal progression associated with antiplatelet therapy in patients with advanced chronic kidney disease (CKD) is controversial. METHODS:We enrolled 1301 adult patients with advanced CKD treated with erythropoiesis stimulating agents f...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2016.11.009

    authors: Hsiao KC,Huang JY,Lee CT,Hung TW,Liaw YP,Chang HR

    更新日期:2017-04-01 00:00:00

  • The role of tenofovir in preventing and treating hepatitis B virus (HBV) reactivation in immunosuppressed patients. A real life experience from a tertiary center.

    abstract:INTRODUCTION/AIM:Patients who present HBV reactivation during immunosuppressive treatment are prone to develop life threatening decompensation of the liver function, therefore prophylaxis and treatment are strongly recommended. So far there are no data regarding the role of tenofovir in this context. Therefore, the aim...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2014.06.028

    authors: Koskinas JS,Deutsch M,Adamidi S,Skondra M,Tampaki M,Alexopoulou A,Manolakopoulos S,Pectasides D

    更新日期:2014-10-01 00:00:00

  • Lower dose direct oral anticoagulants and improved survival: A combined analysis in patients with established atherosclerosis.

    abstract:BACKGROUND:Antithrombotic/anticoagulation effects of direct oral anticoagulants (DOACs) are dose-dependent. However, recent observations suggest that administering lower dose DOACs may better protect against all-cause mortality. We investigated whether, in patients with established atherosclerosis, DOAC dose selection ...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2020.09.007

    authors: Cappato R,Chiarito M,Giustozzi M,Briani M,Ali H,Riva L,Bonitta G,Lodigiani C,Furlanello F,Balla C,Lupo P,Stefanini G

    更新日期:2021-01-01 00:00:00

  • Heart rate and cardiovascular protection.

    abstract::Recent large epidemiological studies have confirmed that an elevated resting heart rate is an independent predictor of cardiovascular and overall mortality in the general population as well as in patients with hypertension, coronary heart disease and chronic heart failure. Pathophysiological studies indicate that a hi...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejim.2015.02.009

    authors: Caetano J,Delgado Alves J

    更新日期:2015-05-01 00:00:00

  • Stroke and renal dysfunction.

    abstract::Stroke is the most frequent neurological disease and represents a continuously evolving medical and social problem. Chronic kidney disease (CKD) is also an important worldwide public health problem. Renal dysfunction carries a substantial risk of cardiovascular morbidity and mortality and an independent, graded associ...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejim.2013.08.710

    authors: Hojs Fabjan T,Hojs R

    更新日期:2014-01-01 00:00:00

  • A case of intravascular lymphomatosis (IVL) presenting as polyneuropathy.

    abstract::Intravascular lymphomatosis (IVL) is a rare, yet important, cause of a variety of unexplained neurological syndromes. In this clinical context, the only clue to the diagnosis may be a significantly raised plasma lactate dehydrogenase (LDH) on a background of clinical features of a systemic illness. ...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2005.06.001

    authors: Wong P,Moonie A,Dennett X,Anpalahan M

    更新日期:2006-01-01 00:00:00

  • Endothelins in health and disease.

    abstract::Endothelins are powerful vasoconstrictor peptides that also play numerous other roles. The endothelin (ET) family consists of three peptides produced by a variety of tissues. Endothelin-1 (ET-1) is the principal isoform produced by the endothelium in the human cardiovascular system, and it exerts its actions through b...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2007.04.002

    authors: Shah R

    更新日期:2007-07-01 00:00:00

  • Reported parental age of death in type 2 diabetic patients with and without established diabetic nephropathy.

    abstract:BACKGROUND:Diabetic patients with renal disease have increased mortality, largely from cardiovascular disease. This could be related to insulin resistance or to other inherited factors. The aim of the present study was to investigate whether there is evidence of the familial aggregation of increased mortality, even in ...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2005.07.005

    authors: Fava S,Hattersley AT

    更新日期:2005-11-01 00:00:00

  • Clinical findings of bacteremic septic arthritis according to the site of acquisition: The overlap between health care-related and community- and nosocomial-acquired cases.

    abstract:BACKGROUND:The site of acquisition of infection may have a major impact on outcome. The health care-related (HCR) environment has recently come under scrutiny. In a group of patients with bacteremic septic arthritis (SA), we compared their characteristics, type of SA, microbiology and prognosis according to the site of...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2015.11.013

    authors: Murillo O,Gomez-Junyent J,Grau I,Ribera A,Cabrera C,Pedrero S,Tubau F,Nolla JM,Ariza J,Pallares R

    更新日期:2016-03-01 00:00:00

  • Interference in free thyroxine immunoassay.

    abstract::We report two patients who presented with non-specific symptoms of tiredness that prompted their clinician to order a thyroid function test. In both cases, free thyroxine (T4) was reported to be high, with a normal thyroid-stimulating hormone (TSH). Repeated blood tests from the same laboratory using the same assay me...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2007.05.009

    authors: Ghosh S,Howlett M,Boag D,Malik I,Collier A

    更新日期:2008-05-01 00:00:00

  • Definition of tachycardia for risk stratification of pulmonary embolism.

    abstract:BACKGROUND:Tachycardia is a reliable predictor of adverse outcomes in normotensive patients with acute pulmonary embolism (PE). However, different prognostic relevant heart rate thresholds have been proposed. The aim of the study was to investigate the prognostic performance of different thresholds used for defining ta...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2020.08.009

    authors: Hobohm L,Becattini C,Ebner M,Lerchbaumer MH,Casazza F,Hasenfuß G,Konstantinides SV,Lankeit M

    更新日期:2020-12-01 00:00:00

  • Prevalence, risk factors and proteomic bioprofiles associated with heart failure in rheumatoid arthritis: The RA-HF study.

    abstract:BACKGROUND:Rheumatoid arthritis (RA) patients have high risk of heart failure (HF). AIMS:Identifying the risk factors and mechanistic pathways associated with HF in patients with RA. METHODS:Cohort study enrolling 355 RA patients. HF was defined according to the ESC criteria. 93 circulating protein-biomarkers (91CVDI...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2020.11.002

    authors: Ferreira MB,Fonseca T,Costa R,Marinhoc A,Carvalho HC,Oliveira JC,Zannad F,Rossignol P,Gottenberg JE,Saraiva FA,Rodrigues P,Barros AS,Ferreira JP

    更新日期:2020-11-06 00:00:00

  • First comes the A, then the B: what we learned from the COVID-19 outbreak.

    abstract::The SARS-CoV-2 epidemic, which has spread to many countries around the world, has hit Europe particularly hard. From our point of view, in a rural emergency department (with an annual patient census of around 25,000) in northeastern Italy, it is necessary to preserve the hospital and prevent it from becoming an outbre...

    journal_title:European journal of internal medicine

    pub_type: 信件

    doi:10.1016/j.ejim.2020.06.031

    authors: Copetti R,Amore G,Di Gioia CC,Orso D

    更新日期:2020-10-01 00:00:00

  • Resistant hypertension in visceral obesity.

    abstract:BACKGROUND:Visceral obesity increases the risk of arterial hypertension (78% of cases of hypertension in men and 65% of cases in women). The aim of the study is to assess the role of visceral obesity in causing resistant hypertension (RH). METHODS:The survey was performed on 5065 hypertensive patients with visceral ob...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2012.04.012

    authors: Holecki M,Duława J,Chudek J

    更新日期:2012-10-01 00:00:00

  • Persistent dyspnea complaints at long-term follow-up after an episode of acute pulmonary embolism: results of a questionnaire.

    abstract:BACKGROUND:There is a lack of information on long term complications of patients with pulmonary embolism (PE), including chronic complaints of dyspnea. METHODS:Consecutive patients with a prior diagnosis of acute PE and an age and gender matched control group with no medical history of PE were presented with a questio...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2008.02.006

    authors: Klok FA,Tijmensen JE,Haeck ML,van Kralingen KW,Huisman MV

    更新日期:2008-12-01 00:00:00

  • A quarter of admitted poisoned patients have a mild poisoning and require no treatment: An observational study.

    abstract:BACKGROUND:Poisoned patients are frequently admitted following Emergency Department (ED) presentation, while the necessity of such admissions is hardly investigated. We determined the proportion and characteristics of poisoned patients who were admitted, but in retrospect had an uneventful admission. METHODS:For this ...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2019.05.012

    authors: Hondebrink L,Rietjens SJ,Donker DW,Hunault CC,van den Hengel-Koot I,Verputten PM,de Vries I,Kaasjager KAH,Dekker D,de Lange DW

    更新日期:2019-08-01 00:00:00

  • Acute respiratory failure due to diaphragmatic weakness revealing a polymyositis.

    abstract::Of the different respiratory disorders that complicate the course of polymyositis, diaphragmatic weakness is one that is seldom described and most often suspected rather than confirmed. We report a case of severe diaphragmatic weakness as a cause of acute respiratory failure revealing a polymyositis. The diaphragmatic...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/s0953-6205(02)00015-8

    authors: Dauriat G,Stern JB,Similowski T,Herson S,Belmatoug N,Marceau A,Fantin B,Fournier M,Mal H

    更新日期:2002-05-01 00:00:00

  • Chronic disseminated intravascular coagulation caused by an aorto-bifemoral aneurysm.

    abstract::This article reports the case of a patient with chronic disseminated intravascular coagulation that led to the diagnosis of an otherwise asymptomatic aorto-bifemoral aneurysm. The bleeding disorder completely resolved with the surgical resection of the aneurysm. Fibrinogen replacement therapy prior to invasive diagnos...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2004.11.012

    authors: Jimeno A,Toledo T,Moya I,González-Barber A

    更新日期:2005-08-01 00:00:00

  • Time to face the challenge of multimorbidity. A European perspective from the joint action on chronic diseases and promoting healthy ageing across the life cycle (JA-CHRODIS).

    abstract::Research on multimorbidity has rapidly increased in the last decade, but evidence on the effectiveness of interventions to improve outcomes in patients with multimorbidity is limited. The European Commission is co-funding a large collaborative project named Joint Action on Chronic Diseases and Promoting Healthy Ageing...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejim.2015.02.020

    authors: Onder G,Palmer K,Navickas R,Jurevičienė E,Mammarella F,Strandzheva M,Mannucci P,Pecorelli S,Marengoni A,Joint Action on Chronic Diseases and Promoting Healthy Ageing across the Life Cycle (JA-CHRODIS).

    更新日期:2015-04-01 00:00:00

  • Blessings of the grape.

    abstract::Numerous epidemiological studies have shown an inverse correlation between moderate consumption of alcoholic drinks and the risk of coronary heart disease. Wine, especially red wine, may be more favorable in this respect than beer or spirits because of its high content of flavonoids. These polyphenols originate from t...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/s0953-6205(01)00170-4

    authors: van de Wiel A,van Golde PH,Hart HC

    更新日期:2001-12-01 00:00:00

  • The annual yield of diagnostic endoscopy of the lower digestive tract.

    abstract::BACKGROUND: Endoscopy of the colon and rectum has become a standard diagnostic procedure. No data are presented in the literature on the annual yield or on morbidity patterns. A large, cross-sectional, single-center study was done in order to detect the annual yield of endoscopy of the colon and rectum. METHODS: All c...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2004.07.015

    authors: Loffeld RJ,van der Putten AB

    更新日期:2005-02-01 00:00:00

  • Hypersersensitivity and Kounis syndrome due to a viper bite.

    abstract::A 60-year-old male was bitten by a venomous snake (Vipera ammodytes) and gradually developed signs of an allergic reaction including generalized itching, generalized rash, and chest discomfort. This was followed by severe retrosternal pain with electrocardiographic evidence of an inferior myocardial ischemia progressi...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2005.11.016

    authors: Frangides C,Kouni S,Niarchos C,Koutsojannis C

    更新日期:2006-05-01 00:00:00

  • Dual renin-angiotensin system blockade: in patients with single functioning kidney and proteinuria.

    abstract:AIM:Dual blockade of renin-angiotensin system (RAS) has increased antiproteinuric effects and it has been increasingly used on patients with proteinuria, but could have secondary effects when this kind of treatment is administered to patients with single functioning kidney. The aim of this study has been to assess the ...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章

    doi:10.1016/j.ejim.2008.06.002

    authors: Robles NR,Ruiz Jiménez B,Hernández Gallego R,Ruiz-Calero R,Sánchez Casado E,Cubero JJ

    更新日期:2009-03-01 00:00:00

  • Erectile dysfunction and adherence to antihypertensive therapy: Focus on β-blockers.

    abstract::The management of arterial hypertension is very challenging in everyday clinical practice. Blood pressure control rates remain disappointingly low, despite intense efforts. Poor adherence to antihypertensive treatment is among the main causes of inadequate blood pressure control. Among the various parameters leading t...

    journal_title:European journal of internal medicine

    pub_type: 杂志文章,评审

    doi:10.1016/j.ejim.2020.07.009

    authors: Manolis A,Doumas M,Ferri C,Mancia G

    更新日期:2020-11-01 00:00:00