Abstract:
:Venous thromboembolism (VTE) is frequent in patients hospitalized in Internal Medicine wards. It carries a considerable morbidity and mortality. Recommendations for use of anticoagulation are graded 1A in leading evidence-based consensus guidelines. Implementation of these guidelines is suboptimal. Lack of awareness seems to be an important factor for the low implementation rate of thromboprophylaxis in Internal Medicine wards, but other factors may be equally important: some clinicians find the data favoring thromboprophylaxis unconvincing or believe that pharmacological prevention is too risky for the average medical inpatient. The following review will show that although there is a dispute about the clinical importance of some manifestations of thromboembolic disease, anticoagulation significantly reduces the risk for clinically relevant VTE. The bleeding risk in most patients is low and does not outweigh the benefit of treatment. Pharmacological or mechanical thromboprophylaxis is cost-effective when administered to at-risk patients. Better awareness and judicious use of risk assessment models should help the attending physician to balance the risk of VTE against the potential bleeding risk.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Roth-Yelinek Bdoi
10.1016/j.ejim.2011.11.005subject
Has Abstractpub_date
2012-04-01 00:00:00pages
236-9issue
3eissn
0953-6205issn
1879-0828pii
S0953-6205(11)00269-Xjournal_volume
23pub_type
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journal_title:European journal of internal medicine
pub_type: 杂志文章
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更新日期:2019-08-01 00:00:00
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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doi:10.1016/j.ejim.2004.10.022
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
pub_type: 临床试验,杂志文章
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更新日期:2009-07-01 00:00:00
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更新日期:2021-01-12 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
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更新日期:2018-12-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 临床试验,杂志文章
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journal_title:European journal of internal medicine
pub_type: 杂志文章,多中心研究
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journal_title:European journal of internal medicine
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journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
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更新日期:2016-03-01 00:00:00
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