Abstract:
BACKGROUND:There are ethnic differences in the incidence of venous thromboembolism. This is the first nationwide study to examine whether there is an association between country of birth in first-generation immigrants and first hospitalisation for venous thrombosis (VT) and pulmonary embolism (PE), and to study whether a similar association exists in second-generation immigrants. METHODS:The study is a nationwide follow-up study. The study subjects were first- and second-generation immigrants residing in Sweden between January 1, 1964 and December 31, 2007. The reference population comprised first- and second-generation Swedish-born individuals. Standardised incidence ratios (SIRs) for VT and PE, standardised with regard to age, geographic region of residence, time period, and socioeconomic status, were estimated by sex in first- and second-generation immigrants. RESULTS:First-generation male and/or female immigrants from Greece, Italy, Spain, Finland, Baltic countries, Central Europe, Eastern Europe, Russia, Latin America, Turkey, Iran, and Iraq had a lower risk of VT and/or PE than Swedish-born individuals. The lower risk of VT and/or PE in some first-generation immigrant groups was not replicated in the second generation. However, in certain second-generation immigrant groups, the risk of VT/PE was similar to that in the corresponding parental groups. CONCLUSIONS:Country of birth affects the risk of VT and PE in several immigrant groups. Our study indicates that ethnicity-related inherited and acquired venous thromboembolism risk factors play a role in the aetiology of venous thromboembolism. Ethnic differences in thromboembolism risk even exist in Caucasian European populations, and may thus be important to consider in genetic studies.
journal_name
Eur J Intern Medjournal_title
European journal of internal medicineauthors
Zöller B,Li X,Sundquist J,Sundquist Kdoi
10.1016/j.ejim.2011.07.015subject
Has Abstractpub_date
2012-01-01 00:00:00pages
40-7issue
1eissn
0953-6205issn
1879-0828pii
S0953-6205(11)00160-9journal_volume
23pub_type
杂志文章abstract::The International Society of Hypertension (ISH) has recently developed practice guidelines for the management of hypertension in adults aged ≥18 years. Conceptually, the 2020 ISH Guidelines are closer to the 2018 ESC/ESH Guidelines rather than to the 2017 ACC/AHA Guidelines. The ISH Guidelines have two distinctive fea...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2020.09.001
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND & AIMS:There is limited data comparing influence of age on the presentation, clinical course, and therapeutic response of patients with ulcerative colitis. We aimed to compare the demographic and clinical characteristics of patients diagnosed with UC in older age vs. adulthood vs. early age. METHODS:Five-hu...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2012.12.014
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:Melatonin exerts multiple biological effects with potential impact on human diseases. This is underscored by genetic studies that demonstrated associations between melatonin receptor type 2 gene (MTNR1B) polymorphisms and characteristics of type 2 diabetes. We set out to test the hypothesis whether genetic v...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2013.03.015
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:The prognostic significance of hypoalbuminemia and the dynamic changes in serum albumin during hospitalization in internal medicine wards has not been sufficiently investigated. METHODS:Demographic, clinical and laboratory data were collected from 276 patients admitted to our internal medicine ward for a va...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2013.08.004
更新日期:2013-12-01 00:00:00
abstract::We describe an 80-year-old patient who developed Staphylococcus aureus septicemia several days after the implantation of a double stent in the proximal and mid-left anterior descending artery. The infection was complicated by multiple abscesses in the lungs and liver, as well as by bilateral bacterial endophthalmitis ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2004.10.010
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:To describe trends in the rates and short-term outcomes of renal transplants (RTx) among patients with or without diabetes in Spain (2002-2013). METHODS:We used national hospital discharge data to select all hospital admissions for RTx. We divided the study period into four three-year periods. Rates were ca...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2016.07.031
更新日期:2017-01-01 00:00:00
abstract::The names of many drugs look or sound like those of other drugs, which leads to confusion and potentially harmful medication errors. We report a nearly fatal permutation between two drugs including a vitamin K antagonist that resulted in a 68-year-old man being admitted to the emergency department with severe, spontan...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2007.03.018
更新日期:2008-03-01 00:00:00
abstract::Enteric fever (EF) is the most common bacteremic disease affecting travelers to the tropics. For more than a decade, fluoroquinolones have been considered the drugs of choice for EF. However, recent reports have raised concern about fluoroquinolone resistance. Treatment with ciprofloxacin failed in a traveler with Sal...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2006.09.016
更新日期:2007-03-01 00:00:00
abstract::Background: Thrombomodulin (TM) is a membrane glycoprotein in the vascular endothelium. It may be cleaved from endothelial cells and released into the circulation. The plasma TM level depends on the integrity of the endothelium and the clearance of the molecule. The physiological role of soluble TM forms is still uncl...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/s0953-6205(00)00066-2
更新日期:2000-04-01 00:00:00
abstract:INTRODUCTION:Patients with chronic hepatitis C (CHC) and end-stage renal disease (ESRD) on dialysis are difficult to treat and show higher dropout rates during treatment. The aim of this study was to analyze the treatment outcomes in patients with CHC and underlying end-stage renal disease on dialysis in Korea. METHOD...
journal_title:European journal of internal medicine
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ejim.2015.03.011
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Mallory-Weiss syndrome is defined by upper gastrointestinal bleeding from vomiting-induced mucosal lacerations at the esophago-gastric junction. This study was purposed to investigate the incidence, location, clinical manifestation, diagnosis and effectiveness of treatment (including endoscopic treatment and...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2012.02.005
更新日期:2012-06-01 00:00:00
abstract::Obesity, one of the most prevalent health problems in the Western world, is a chronic and progressive condition. Therefore, as with other chronic diseases, patients with obesity require lifelong treatment. Long-term efficacy and effectiveness of obesity treatments is notoriously poor. This may in part be attributable ...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2007.09.011
更新日期:2008-05-01 00:00:00
abstract:BACKGROUND:To assess the prevalence of decreased iron stores and anemia in pregnant women. To determine whether the risk factors: socio-demographic background, age, BMI, and parity are associated with abnormal hemoglobin concentrations and/or abnormal iron status. METHODS:A longitudinal study was carried out at the De...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2012.04.008
更新日期:2012-09-01 00:00:00
abstract::Patients with systemic lupus erythematosus (SLE) are frequently immunodepressed making them more vulnerable to infections. Preventive vaccination is therefore warranted but has often been withheld owing to fears of a link between infection and autoimmunity, and the possibility of inducing or exacerbating lupus after v...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2008.07.017
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND & AIMS:Non-alcoholic fatty liver disease was traditionally interpreted as a condition which may progress to liver-related complications. However, the increased mortality is primarily a result of cardiovascular diseases. It has been suggested that fatty liver can be considered as the hepatic consequence of th...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2014.05.012
更新日期:2014-07-01 00:00:00
abstract:BACKGROUND:Low serum levels of alkaline phosphatase (ALP) are a hallmark of hypophosphatasia. However, the clinical significance and the underlying genetics of low ALP in unselected populations are unclear. METHODS:In order to clarify this issue, we performed a clinical, biochemical and genetic study of 42 individuals...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2015.12.019
更新日期:2016-04-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2008.09.013
更新日期:2009-03-01 00:00:00
abstract::The need for anticoagulation in patients with atrial fibrillation (AF), and the inherent limitations of warfarin have fostered the search for direct oral anticoagulant drugs (DOACs). In recent years, inhibitors of thrombin (Dabigatran etexilate) and of activated factor X (Rivaroxaban, Apixaban) have become clinically ...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2013.01.021
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Many activities contribute to reduce drug-related problems. Among them, the medication reconciliation (MR) is used to compare the best possible medication history (BPMH) and the current admission medication order (AMO) to identify and solve unintended medication discrepancies (UMD). This study aims to assess...
journal_title:European journal of internal medicine
pub_type: 临床试验,杂志文章
doi:10.1016/j.ejim.2014.09.012
更新日期:2014-11-01 00:00:00
abstract::Background: Impaired gastrointestinal and gallbladder motility, as a complication of long-lasting diabetes mellitus, has been ascribed to the possible development of autonomic neuropathy, although the intervention of hormonal factors may not completely be excluded. In this regard, cholecystokinin (CCK), a gut hormone ...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/s0953-6205(02)00003-1
更新日期:2002-03-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2008.09.001
更新日期:2009-05-01 00:00:00
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journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2010.08.003
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Whether diabetes mellitus (DM) is associated with a higher risk of perioperative mortality and mortality after liver transplantation (LTx) remains unclear. METHODS:We compared the risk of postoperative mortality and morbidity in DM and non-DM patients undergoing LTx. We enrolled 558 DM patients who underwen...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2015.05.010
更新日期:2015-07-01 00:00:00
abstract::Allergic reactions to corticosteroids are unexpected as they seem to contradict their pharmacodynamic action. Nevertheless, they are not infrequent, with an estimated incidence of up to 4% for cutaneous reactions. Systemic reactions are rarely reported, but their incidence might be underestimated. We report here an un...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2005.04.004
更新日期:2005-12-01 00:00:00
abstract::Background: We recently observed that a short course of trimethoprim 300 mg b.i.d. in healthy volunteers can cause a substantial increase in fasting plasma homocysteine levels, up to concentrations reportedly associated with atherothrombotic complications. The purpose of this study was to determine whether primary Pne...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/s0953-6205(01)00134-0
更新日期:2001-07-01 00:00:00
abstract:BACKGROUND:The site of acquisition of infection may have a major impact on outcome. The health care-related (HCR) environment has recently come under scrutiny. In a group of patients with bacteremic septic arthritis (SA), we compared their characteristics, type of SA, microbiology and prognosis according to the site of...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2015.11.013
更新日期:2016-03-01 00:00:00
abstract::The European School of Internal Medicine (ESIM) is a meeting aimed at young physicians training in internal medicine throughout Europe. Since 1998 the school has been held annually, and in this report we reflect on our experiences during the recent school in Brighton in July 2010. The school combined a broad mix of le...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2011.01.006
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Cranial nerve involvement is commonly observed in patients with tuberculous meningitis. The present study evaluated the incidence, predictors and prognostic significance of cranial nerve involvement in tuberculous meningitis. MATERIALS AND METHOD:One hundred-fifty-eight adult patients with tuberculous menin...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2011.01.007
更新日期:2011-06-01 00:00:00
abstract::Within a few decades half of the patients with non-valvular atrial fibrillation (AF) will be older than 80 years. These patients are at particularly high risk of thromboembolism (Scylla) but also of the hemorrhagic complications of thromboprophylaxis (Charybdis). A frequent compromise is to use as antithrombotic agent...
journal_title:European journal of internal medicine
pub_type: 杂志文章,评审
doi:10.1016/j.ejim.2013.02.001
更新日期:2013-06-01 00:00:00
abstract:OBJECTIVE:To assess security of "blind" percutaneous liver biopsy as an ambulatory procedure. MATERIAL AND METHODS:Defining inclusion criteria, surveillance protocol, data from ultrasonography done 6 h after procedure and complications. RESULTS:We analysed 192 percutaneous liver biopsies done between 2000-2007. There...
journal_title:European journal of internal medicine
pub_type: 杂志文章
doi:10.1016/j.ejim.2009.02.002
更新日期:2009-09-01 00:00:00