Systemic lupus erythematosus and vaccination.

Abstract:

:Patients with systemic lupus erythematosus (SLE) are frequently immunodepressed making them more vulnerable to infections. Preventive vaccination is therefore warranted but has often been withheld owing to fears of a link between infection and autoimmunity, and the possibility of inducing or exacerbating lupus after vaccination. The data published in the literature suggest that vaccination of lupus patient is safe, except for live vaccines. Their efficacy is lower than in healthy subjects but protection seems to be sufficient. But further large-scale studies are required to confirm these statements.

journal_name

Eur J Intern Med

authors

Millet A,Decaux O,Perlat A,Grosbois B,Jego P

doi

10.1016/j.ejim.2008.07.017

subject

Has Abstract

pub_date

2009-05-01 00:00:00

pages

236-41

issue

3

eissn

0953-6205

issn

1879-0828

pii

S0953-6205(08)00215-X

journal_volume

20

pub_type

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