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Acute chest syndrome in sickle-cell trait; Two case reports in persons of Mediterranean origin and review of the literature.

Abstract：

:Sickle-cell trait has been characterized as a benign condition. However, life-threatening complications sometimes develop. Acute chest syndrome (ACS) is usually described in homozygous sickle cell disease, but it rarely develops in individuals with sickle-cell trait. Two cases of ACS in patients with sickle-cell trait are reported here. Factors such as advanced age at the time of presentation and absent past medical and family history can be misleading. Although ACS in sickle-cell trait has thus far only been reported in persons of Afro-American origin, persons of Mediterranean origin can, on rare occasions, also experience the syndrome.

journal_name

Eur J Intern Med

journal_title

European journal of internal medicine

authors

Dourakis SP,Alexopoulou A,Papageorgiou C,Kaloterakis A,Hadziyannis SJ

doi

10.1016/j.ejim.2004.03.010

subject

Has Abstract

pub_date

2004-07-01 00:00:00

pages

248-250

issue

4

eissn

0953-6205

issn

1879-0828

pii

S0953620504000950

journal_volume

15

pub_type

杂志文章

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