Changes in Glial Fibrillary Acidic Protein Immunoreactivity in Response to Experimental Hepatic Encephalopathy in the Rat Hippocampus.

abstract：PURPOSE:Aging is believed to affect epigenetic marking of brain DNA with 5-methylcytosine (5mC) and possibly via the 5mC to 5-hydroxymethylcytosine (5hmC) conversion by TET (ten-eleven translocation) enzymes. We investigated the impact of aging on hippocampal DNA 5-hydroxymethylation including in the sequence of aging-...

journal_title：Restorative neurology and neuroscience

authors： Chen H,Dzitoyeva S,Manev H

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:Interacting with others by reading their emotional expressions is an essential social skill in humans. How this ability develops during infancy and what brain processes underpin infants' perception of emotion in different modalities are the questions dealt with in this paper. METHODS:Literature review. RESULT...

journal_title：Restorative neurology and neuroscience

authors： Grossmann T

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To report the safety and efficacy of a novel therapeutic trial with umbilical cord blood (UCB) and concomitant recombinant human erythropoietin (rhEPO), which was tried for three cases of severe traumatic brain injury (TBI) in rehabilitation. DESIGN:Case series. SETTING:University hospital setting. PARTICI...

journal_title：Restorative neurology and neuroscience

authors： Min K,Song J,Lee JH,Kang MS,Jang SJ,Kim SH,Kim M

更新日期：2013-01-01 00:00:00

abstract：:In four patients with left visuo-spatial hemineglect and right brain- damage, the therapeutic effects of Transcutaneous Electrical Nervous Stimulation (TENS) of the left neck muscles, associated with a non-specific treatment, and of a specific rehabilitation paradigm were investigated. The two treatments were given fo...

journal_title：Restorative neurology and neuroscience

authors： Pizzamiglio L,Vallar G,Magnotti L

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:The quality of presurgical evaluation in focal extratemporal epilepsy surgery is highly dependent on precise structural and functional identification of the epileptic focus. Navigated transcranial magnetic stimulation (nTMS) is a tool that combines the spatial information of high-resolution magnetic resonance i...

journal_title：Restorative neurology and neuroscience

authors： Schmidt S,Holst E,Irlbacher K,Oltmanns F,Merschhemke M,Brandt SA

更新日期：2010-01-01 00:00:00

abstract：:While the regenerating capacity of peripheral nerves has been the subject of intensive study, little is known about the regenerative capacity of the autonomic nervous system. Using an animal model, where the pupil diameter of the eye in the rat serves as a parameter of autonomic function, we studied whether systemic t...

journal_title：Restorative neurology and neuroscience

authors： Vandertop WP,de Vries WB,Notermans NC,Tulleken CA,Gispen WH

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Patients suffering from chronic disorders of consciousness (DOC), including minimally conscious state (MCS) and unresponsive wakefulness syndrome (UWS), typically show an awareness impairment paralleled by a significant reflex hyper-excitability, which depend on the cortical deafferentation following brain-d...

journal_title：Restorative neurology and neuroscience

authors： Naro A,Bruno R,Leo A,Russo M,Salviera C,Bramanti A,Bramanti P,Calabrò RS

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:This study investigated whether enrichment improves hindlimb movement following complete spinal cord transection and transplantation of olfactory ensheathing glia (OEG), with or without a Schwann cell (SC) bridge. METHODS:Motor activity was encouraged through provision of motor enrichment housing (MEH); a mult...

journal_title：Restorative neurology and neuroscience

authors： Moon LD,Leasure JL,Gage FH,Bunge MB

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:In brain-computer interfaces (BCIs), electrical brain signals during motor imagery are utilized as commands connecting the brain to a computer. To use BCI in patients with stroke, unique brain signal changes should be characterized during motor imagery process. This study aimed to examine the trial-dependent mo...

journal_title：Restorative neurology and neuroscience

authors： Lee M,Park CH,Im CH,Kim JH,Kwon GH,Kim L,Chang WH,Kim YH

更新日期：2015-08-26 00:00:00

abstract：PURPOSE:This article reviews the literature on far transfer effects in training of older adults. METHODS:Adapting a taxonomy of transfer developed by Barnett and Ceci (2002), to rehabilitation or enhancement of existing cognitive skills; results of studies assessing transfer effects from training of memory, reasoning,...

journal_title：Restorative neurology and neuroscience

authors： Zelinski EM

更新日期：2009-01-01 00:00:00

abstract：PURPOSE:Repetitive mild traumatic brain injury (TBI) is a major military and sports health concern. The purpose of this study was to determine if a diet rich in omega-3 fatty acids would reduce cognitive deficits and neuronal cell death in a novel fluid percussion rat model of repetitive mild TBIs. METHODS:Thirty-two ...

journal_title：Restorative neurology and neuroscience

authors： Wang T,Van KC,Gavitt BJ,Grayson JK,Lu YC,Lyeth BG,Pichakron KO

更新日期：2013-01-01 00:00:00

abstract：:A long-term goal in motor rehabilitation is that treatment is not selected on the basis of 'schools of thought', but rather, based on knowledge about efficacy and effectiveness of specific interventions for specific situations (e.g. functional syndromes). Motor dysfunction after stroke or TBI can be caused by many dif...

journal_title：Restorative neurology and neuroscience

authors： Platz T,Hesse S,Mauritz KH

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:High definition transcranial direct current stimulation (HD-tDCS) has been administered over single brain regions for small numbers of sessions. Safety, feasibility and tolerability of HD-tDCS over multiple brain regions, multiple daily stimulations and long periods are not established. OBJECTIVE:We studied...

journal_title：Restorative neurology and neuroscience

authors： Turski CA,Kessler-Jones A,Chow C,Hermann B,Hsu D,Jones J,Seeger SK,Chappell R,Boly M,Ikonomidou C

更新日期：2017-01-01 00:00:00

abstract：PURPOSE:Several studies have shown that transcranial direct current stimulation (tDCS) is a useful tool to enhance language recovery in aphasia. It has also been suggested that modulation of the neurotrophin brain-derived neurotrophic factor (BDNF) might be part of the mechanisms involved in tDCS effects on synaptic co...

journal_title：Restorative neurology and neuroscience

authors： Marangolo P,Fiori V,Gelfo F,Shofany J,Razzano C,Caltagirone C,Angelucci F

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Contralateral primary sensori-motor cortex (SM1) activation by passive movement was investigated by functional MRI (fMRI) at the early stage of stroke, to determine whether SM1 activation can be used to predict the degree of motor recovery of the hemiplegic hand. METHODS:We studied 17 stroke patients who showe...

journal_title：Restorative neurology and neuroscience

authors： Jang SH,Kim YH,Chang Y,Han BS,Byun WM,Chang CH

更新日期：2004-01-01 00:00:00

abstract：PURPOSE:Repairing the spinal cord with peripheral nerve grafts (PNG) and adjuvant acidic fibroblast growth factor (FGF1) has previously resulted in partial functional recovery. To aid microsurgical placement of PNGs, a graft holder device was previously developed by our group. In hope for a translational development we...

journal_title：Restorative neurology and neuroscience

authors： Nordblom J,Persson JK,Aberg J,Blom H,Engqvist H,Brismar H,Sjödahl J,Josephson A,Frostell A,Thams S,Brundin L,Svensson M,Mattsson P

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To investigate whether repeated sessions of motor imagery and action observation modulate corticospinal excitability (CE) over time, whether these processes are susceptible of any training effect and if such effect might be different for the dominant and non dominant hemisphere. METHODS:11 subjects underwent t...

journal_title：Restorative neurology and neuroscience

authors： Bianco G,Feurra M,Fadiga L,Rossi A,Rossi S

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To demonstrate, in a proof-of-concept study, whether potentiating ipsilesional higher motor areas (premotor cortex and supplementary motor area) augments and accelerates recovery associated with constraint induced movement. METHODS:In a randomized, double-blinded pilot clinical study, 12 patients with chronic ...

journal_title：Restorative neurology and neuroscience

authors： Cunningham DA,Varnerin N,Machado A,Bonnett C,Janini D,Roelle S,Potter-Baker K,Sankarasubramanian V,Wang X,Yue G,Plow EB

更新日期：2015-01-01 00:00:00

abstract：:Many ocular diseases (such as glaucoma, diabetic retinopathy, age-related macular degeneration, and traumatic eye injuries) can result in the degeneration of retinal cells and the subsequent loss of vision. Some kinds of treatments, such as drugs, stem cell transplantation and surgery are reported to be effective in c...

journal_title：Restorative neurology and neuroscience

authors： Li HY,Rong SS,Hong X,Guo R,Yang FZ,Liang YY,Li A,So KF

更新日期：2019-01-01 00:00:00

abstract：:Melatonin (MLT) is a methoxyindole secreted principally by the pineal gland. It is synthesized at night under normal environmental conditions. The endogenous rhythm of secretion is generated by the suprachiasmatic nuclei and entrained by the light/dark cycle. Light is able to both suppress or synchronize melatonin pro...

journal_title：Restorative neurology and neuroscience

authors： Claustrat B,Brun J,Geoffriau M,Chazot G

更新日期：1998-06-01 00:00:00

abstract：:Non-invasive brain stimulation techniques, such as repetitive transcranial magnetic stimulation (rTMS), can modify cortical excitability in a lasting fashion. The modification can be bi-directional in nature and holds considerable therapeutic promise for a number of neurological conditions. However, the effectiveness ...

journal_title：Restorative neurology and neuroscience

authors： Todd G,Ridding MC

更新日期：2010-01-01 00:00:00

abstract：:Many of the present limitations of peripheral nerve repair might be overcome by performing nerve repairs at the axon level. One approach to nerve repair at this level would be to implant a neuroprosthesis in the form of a microelectronic switchboard which could route the connections of regenerated axons to their corre...

journal_title：Restorative neurology and neuroscience

authors： Rosen JM,Grosser M,Hentz VR

更新日期：1990-01-01 00:00:00

abstract：:To examine the regeneration capacity of dorsal septohippocampal neurons in the presence of an artificial growth-promoting substrate, biocompatible polymeric hydrogels were implanted between the septum and the hippocampus in a fimbria-fornix lesion cavity. Unmodified (control) or aminosugar-containing (glucosamines or ...

journal_title：Restorative neurology and neuroscience

authors： Duconseille E,Woerly S,Kelche C,Will B,Cassel JC

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:The purpose of this study was to delineate the relationship between several types of T1-weighted MRI pathology and motor rehabilitation potential following Constraint Induced Movement therapy (CI therapy) in chronic stroke. METHODS:Stepwise regression was employed (n = 80) to identify predictors of motor recov...

journal_title：Restorative neurology and neuroscience

authors： Gauthier LV,Mark VW,Taub E,McCullars A,Barghi A,Rickards T,Hicks J,Uswatte G

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Traumatic brain injury (TBI) -induced brain edema can be reduced by acute progesterone (PROG) treatment in young adult males and females, and in aged males. To extend these findings we tested these hypotheses: 1. Acute PROG treatment post-TBI will reduce cortical edema in aged females as much as in young adults...

journal_title：Restorative neurology and neuroscience

authors： Kasturi BS,Stein DG

更新日期：2009-01-01 00:00:00

abstract：:Regenerating nerve fiber sprouts enveloped by olfactory bulb (OB) ensheathing cells (ECs) seem to escape the inhibitory influence of gliotic tissue. Accordingly, these cells may be useful for general repair of injured CNS. Relatively large numbers of ECs could be purified from confluent cultures of adult rat olfactory...

journal_title：Restorative neurology and neuroscience

authors： Gudiño-Cabrera G,Nieto-Sampedro M

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Low-frequency rTMS can induce upregulation of excitability in the contralateral hemisphere by interhemispheric interaction. OBJECTIVE:The aim of this study was to compare the effects of interhemispheric modulation on hemodynamic changes after applying low-frequency rTMS over the anatomical hand knob (HK) an...

journal_title：Restorative neurology and neuroscience

authors： Kim J,Kim H,Lee J,Lee HJ,Na Y,Chang WH,Kim YH

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Focal dystonia in musicians (MD) is a task-specific movement disorder with a loss of voluntary motor control during instrumental playing. Defective inhibition on different levels of the central nervous system is involved in the pathophysiology. Sensorimotor retraining is a therapeutic approach to MD and aims...

journal_title：Restorative neurology and neuroscience

authors： Buttkus F,Baur V,Jabusch HC,de la Cruz Gomez-Pellin M,Paulus W,Nitsche MA,Altenmüller E

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:Accurate coil placement over a target area is critical during transcranial magnetic stimulation (TMS), as small deviations can alter testing outcomes. Accordingly, frameless stereotaxic systems (FSS) are recommended for reliable coil placement during TMS applications. However, FSS is not practical due to the co...

journal_title：Restorative neurology and neuroscience

authors： Washabaugh EP,Krishnan C

更新日期：2016-01-01 00:00:00

abstract：PURPOSE:The aim of the present study was to explore the use of two-photon microscopy for investigating the therapeutic time window of methylprednisolone (MP) treatment after spinal cord injury (SCI). METHODS:Twenty-four YFP H-line mice were subjected to hemisection SCI and then divided into four groups. Group 1 receiv...

journal_title：Restorative neurology and neuroscience

authors： Zhang Y,Zhang L,Ji X,Pang M,Ju F,Zhang J,Li W,Zhang S,He Z,Gan WB,Tang P

更新日期：2015-01-01 00:00:00