Extended Multiple-Field High-Definition transcranial direct current stimulation (HD-tDCS) is well tolerated and safe in healthy adults.

abstract：BACKGROUND:After stroke, the learned non-use of a paretic arm is a major obstacle to the improvement of hand function. OBJECTIVE:We examined whether patients with a central paresis could profit from applying the self-regulation strategy of making if-then plans that specify situational triggers to using the paretic arm...

journal_title：Restorative neurology and neuroscience

authors： Marquardt MK,Cohen AL,Gollwitzer PM,Gilbert SJ,Dettmers C

更新日期：2017-01-01 00:00:00

abstract：:Administration of gangliosides accelerates recovery of function after entorhinal cortex lesions on open field activity and learned spatial alternation tasks. In the present study, we examined whether GM1 ganglioside might enhance recovery from bilateral entorhinal cortex lesions on a differential reinforcement of low-...

journal_title：Restorative neurology and neuroscience

authors： Ramirez JJ,MacDonald K,Mañibo J,Payne J,Tuite C

更新日期：1998-01-01 00:00:00

abstract：:In rat sciatic nerves, IGF-I or bFGF was applied distal to a crush to evaluate their effects upon the restoration of the neuromuscular function. In comparison with the recovery following a simple crush, treatment with growth factors resulted in (i) enhanced elongation of regenerating axons ( + 24%) up to day 3 post le...

journal_title：Restorative neurology and neuroscience

authors： Vergara J,Medina L,Maulén J,Inestrosa NC,Alvarez J

更新日期：1993-01-01 00:00:00

abstract：:Many toxic factors are generated during stroke that contribute directly to the death of neurons. Several recent studies suggest that a suicide-like phenomena similar to apoptosis or programmed cell death also contributes to the loss of neurons in stroke. The evidence implicating apoptosis in stroke can be divided into...

journal_title：Restorative neurology and neuroscience

authors： Linnik MD

更新日期：1996-01-01 00:00:00

abstract：PURPOSE:Ischemic stroke is associated with a variety pathophysiological changes affecting both glial and neuronal brain tissue. These changes are mirrored in the release of specific proteins into peripheral blood. Neurone-specific enolase (NSE), protein S100B and glial fibrillary acidic protein (GFAP) are those protein...

journal_title：Restorative neurology and neuroscience

authors： Herrmann M,Ehrenreich H

更新日期：2003-01-01 00:00:00

abstract：:A long-term goal in motor rehabilitation is that treatment is not selected on the basis of 'schools of thought', but rather, based on knowledge about efficacy and effectiveness of specific interventions for specific situations (e.g. functional syndromes). Motor dysfunction after stroke or TBI can be caused by many dif...

journal_title：Restorative neurology and neuroscience

authors： Platz T,Hesse S,Mauritz KH

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:Study the effect of peripheral nerve extracts and BDNF on retinal ganglion cell (RGC) regeneration in adult rats. METHODS:Postmicrosomal fractions were obtained from 7-day, predegenerated, as well as non-predegenerated peripheral adult rats nerves. Autologous connective tissue chambers filled with fibrin were ...

journal_title：Restorative neurology and neuroscience

authors： Swiech-Sabuda E,Gołka B,Kotulska K,Larysz-Brysz M,Górka D,Gołka D,Marcol W,Lewin-Kowalik J

更新日期：2004-01-01 00:00:00

abstract：:The antagonizing effect of the β-adrenoceptor antagonist propranolol (PRP) on the desipramine (DMI)-induced regeneration of brain noradrenergic fibers was examined. The symmetrical sites of the rat frontal cortex were pretreated with 6-hydroxydopamine (6-OHDA). Then, the same cortical site of one hemisphere was infuse...

journal_title：Restorative neurology and neuroscience

authors： Nakamura S

更新日期：1994-01-01 00:00:00

abstract：:Corticomotor excitability is reduced during rhythmic passive movement compared to rest, but it is not known whether the mechanism is purely segmental or includes a supraspinal pathway. To determine how interruption of sensory projections at a supraspinal level affects corticomotor excitability during passive movement,...

journal_title：Restorative neurology and neuroscience

authors： Edwards DJ,Mastaglia FL,Byrnes ML,Fregni F,Pascual-Leone A,Thickbroom GW

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Neuroplastic alterations of cortical excitability and activity represent the likely neurophysiological foundation of learning and memory formation. Beyond their induction, alterations of these processes by subsequent modification of cortical activity, termed metaplasticity, came into the focus of...

journal_title：Restorative neurology and neuroscience

authors： Thirugnanasambandam N,Sparing R,Dafotakis M,Meister IG,Paulus W,Nitsche MA,Fink GR

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:The patients with chronic Disorders of Consciousness (DoC) mostly present with extremely challenging differential diagnosis. The advanced analysis of electroencephalographic (EEG) signals induced by brain stimulation paradigms may provide an appropriate approach to differentiate patients with DoC, besides th...

journal_title：Restorative neurology and neuroscience

authors： Naro A,Leo A,Bruno R,Cannavò A,Buda A,Manuli A,Bramanti A,Bramanti P,Calabrò RS

更新日期：2017-01-01 00:00:00

abstract：:Pyramidal neurons inside transplants of embryonic nervous tissue are capable of generating axonal extrinsic hippocampal fiber connections over considerable distances to appropriate target areas in the mature brain. The establishment of long-distance graft efferents to the lateral septum and to the entorhinal cortex wa...

journal_title：Restorative neurology and neuroscience

authors： Sprick U

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:Understanding the neural mechanisms of stroke recovery is of paramount importance for neurorehabilitation. METHODS:For this purpose, we analyzed several TMS and EEG variables and their association with motor recovery. Thirty-five subjects with chronic stroke were recruited. The neurophysiological examination i...

journal_title：Restorative neurology and neuroscience

authors： Simis M,Doruk D,Imamura M,Anghinah R,Morales-Quezada L,Fregni F,Battistella LR

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Multiple Sclerosis is a heterogeneous disorders involving in early stage gait and balance. Together with immunomodulating therapies, rehabilitation had a crucial role in improving motor tasks and quality of life. Between the emerging techniques, Focal Vibrations (FV) could play a role, but they have been use...

journal_title：Restorative neurology and neuroscience

authors： Spina E,Carotenuto A,Aceto MG,Cerillo I,Silvestre F,Arace F,Paone P,Orefice G,Iodice R

更新日期：2016-09-21 00:00:00

abstract：:Melatonin (MLT) is a methoxyindole secreted principally by the pineal gland. It is synthesized at night under normal environmental conditions. The endogenous rhythm of secretion is generated by the suprachiasmatic nuclei and entrained by the light/dark cycle. Light is able to both suppress or synchronize melatonin pro...

journal_title：Restorative neurology and neuroscience

authors： Claustrat B,Brun J,Geoffriau M,Chazot G

更新日期：1998-06-01 00:00:00

abstract：PURPOSE:Contralateral primary sensori-motor cortex (SM1) activation by passive movement was investigated by functional MRI (fMRI) at the early stage of stroke, to determine whether SM1 activation can be used to predict the degree of motor recovery of the hemiplegic hand. METHODS:We studied 17 stroke patients who showe...

journal_title：Restorative neurology and neuroscience

authors： Jang SH,Kim YH,Chang Y,Han BS,Byun WM,Chang CH

更新日期：2004-01-01 00:00:00

abstract：:The authors used different kinds of peripheral nerve grafts to reconstruct a terminal branch of the brachial plexus (the median nerve) gap of adult Sprague-Dawley rats, including fresh or frozen autografts and allografts from Norway rats. They also performed acellular allograft repopulation by autogenous Schwann cells...

journal_title：Restorative neurology and neuroscience

authors： Accioli-De-Vaconcellos ZA,Kassar-Duchossoy L,Mira JC

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:In brain-computer interfaces (BCIs), electrical brain signals during motor imagery are utilized as commands connecting the brain to a computer. To use BCI in patients with stroke, unique brain signal changes should be characterized during motor imagery process. This study aimed to examine the trial-dependent mo...

journal_title：Restorative neurology and neuroscience

authors： Lee M,Park CH,Im CH,Kim JH,Kwon GH,Kim L,Chang WH,Kim YH

更新日期：2015-08-26 00:00:00

abstract：BACKGROUND:Traumatic brain injury can result in lasting cognitive dysfunction due to degeneration of mature hippocampal neurons as well as the loss of immature neurons within the dentate gyrus. While endogenous neurogenesis affords a partial recovery of the immature neuron population, hippocampal neurogenesis may be en...

journal_title：Restorative neurology and neuroscience

authors： Sama DM,Carlson SW,Joseph B,Saenger S,Metzger F,Saatman KE

更新日期：2018-01-01 00:00:00

abstract：PURPOSE:The quality of presurgical evaluation in focal extratemporal epilepsy surgery is highly dependent on precise structural and functional identification of the epileptic focus. Navigated transcranial magnetic stimulation (nTMS) is a tool that combines the spatial information of high-resolution magnetic resonance i...

journal_title：Restorative neurology and neuroscience

authors： Schmidt S,Holst E,Irlbacher K,Oltmanns F,Merschhemke M,Brandt SA

更新日期：2010-01-01 00:00:00

abstract：PURPOSE:Several recent studies have demonstrated that following short-term monocular deprivation in normal adults, the patched eye, rather than the unpatched eye, becomes stronger in subsequent binocular viewing. However, little is known about the site and nature of the underlying processes. In this study, we examine t...

journal_title：Restorative neurology and neuroscience

authors： Zhou J,Baker DH,Simard M,Saint-Amour D,Hess RF

更新日期：2015-01-01 00:00:00

abstract：:IVth International Symposium on Neural TransplantationEdited by William J. Freed and Jeffrey M. RosensteinThe George Washington University, Washington, DC, USAJuly 12-16, 1992. ...

journal_title：Restorative neurology and neuroscience

authors：

更新日期：1992-01-01 00:00:00

abstract：:Contemporary strategies to promote motor recovery following stroke focus on repetitive voluntary movements. Although successful movement relies on efficient sensorimotor integration, functional outcomes often bias motor therapy toward motor-related impairments such as weakness, spasticity and synergies; sensory therap...

journal_title：Restorative neurology and neuroscience

authors： Bolognini N,Russo C,Edwards DJ

更新日期：2016-04-11 00:00:00

abstract：PURPOSE:Recovery of the most basic shoulder-flexion/elbow-extension components of functional reach is critical for effective arm function following stroke. In order to understand the mechanisms of motor recovery, it is important to characterize the pattern of brain activation during the reach task. METHODS:We evaluate...

journal_title：Restorative neurology and neuroscience

authors： Daly JJ,Hrovat K,Holcomb J,Pundik S

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Exogenously applied BDNF has been shown to rescue rat retinal ganglion cells (RGCs) from axotomy-induced apoptotic death, presumably via activation of its high affinity receptor TrkB. Since both TrkB and BDNF are endogenously expressed in RGCs, auto- or para-crine neurotrophic loops in the retina may be involve...

journal_title：Restorative neurology and neuroscience

authors： Hirsch S,Labes M,Bähr M

更新日期：2000-01-01 00:00:00

abstract：:Purpose: Caspase-3 is known as a crucial effector for apoptotic cell death. Apoptosis has recently been recognized as an important cell death mechanism after spinal cord injury (SCI). This study attempts to define the effect of methylprednisolone (MP) on the activation of caspase-3 in the lesioned area following SCI. ...

journal_title：Restorative neurology and neuroscience

authors： Li X,Oudega M,Dancausse HA,Levi AD

更新日期：2000-01-01 00:00:00

abstract：PURPOSE:The interest in human conscious awareness has increasingly propelled the study of neglect, the most striking occurrence of an acquired lack of conscious experience of space. Neglect syndromes commonly arise after unilateral brain damage that spares primary sensory areas nonetheless leading to a lack of consciou...

journal_title：Restorative neurology and neuroscience

authors： Brozzoli C,Demattè ML,Pavani F,Frassinetti F,Farnè A

更新日期：2006-01-01 00:00:00

abstract：:It is widely accepted that the suprachiasmatic nuclei (SCN) of the hypothalamus serve as biological pacemakers, organizing daily activities. However some circadian rhythms are controlled by extra-SCN structures. Transplantation of fetal donor SCN in SCN-lesioned rodents induces recovery of rhythmic locomotor and drink...

journal_title：Restorative neurology and neuroscience

authors： Le Sauter J,Silver R

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Focal dystonia in musicians (MD) is a task-specific movement disorder with a loss of voluntary motor control during instrumental playing. Defective inhibition on different levels of the central nervous system is involved in the pathophysiology. Sensorimotor retraining is a therapeutic approach to MD and aims...

journal_title：Restorative neurology and neuroscience

authors： Buttkus F,Baur V,Jabusch HC,de la Cruz Gomez-Pellin M,Paulus W,Nitsche MA,Altenmüller E

更新日期：2011-01-01 00:00:00

abstract：PURPOSE:Repetitive mild traumatic brain injury (TBI) is a major military and sports health concern. The purpose of this study was to determine if a diet rich in omega-3 fatty acids would reduce cognitive deficits and neuronal cell death in a novel fluid percussion rat model of repetitive mild TBIs. METHODS:Thirty-two ...

journal_title：Restorative neurology and neuroscience

authors： Wang T,Van KC,Gavitt BJ,Grayson JK,Lu YC,Lyeth BG,Pichakron KO

更新日期：2013-01-01 00:00:00