Reducing the rate of misdiagnosis in patients with chronic disorders of consciousness: Is there a place for audiovisual stimulation?

abstract：PURPOSE:Transgenic manipulation of mouse physiology facilitates the preclinical study of genetic risk factors, neural plasticity, and reactive processes accompanying Alzheimer's disease. Alternatively, entorhinal cortex lesions (ECLs) model pathophysiological denervation and axonal sprouting in rat. Given reports of an...

journal_title：Restorative neurology and neuroscience

authors： Feeney EJ,Stephenson D,Kleiman R,Bove S,Cron C,Moody L,Robinson M,Ramirez JJ

更新日期：2013-01-01 00:00:00

abstract：:Although neurotransmitter-based hypotheses still prevail current thinking about the mechanism of action of psychotropic drugs, recent insight into the pathophysiology of psychiatric disorders has unveiled a range of new therapeutic actions of the drugs used to treat those disorders. Especially antidepressants seem to ...

journal_title：Restorative neurology and neuroscience

authors： Paulzen M,Veselinovic T,Gründer G

更新日期：2014-01-01 00:00:00

abstract：:In rat sciatic nerves, IGF-I or bFGF was applied distal to a crush to evaluate their effects upon the restoration of the neuromuscular function. In comparison with the recovery following a simple crush, treatment with growth factors resulted in (i) enhanced elongation of regenerating axons ( + 24%) up to day 3 post le...

journal_title：Restorative neurology and neuroscience

authors： Vergara J,Medina L,Maulén J,Inestrosa NC,Alvarez J

更新日期：1993-01-01 00:00:00

abstract：PURPOSE:Recovery of the most basic shoulder-flexion/elbow-extension components of functional reach is critical for effective arm function following stroke. In order to understand the mechanisms of motor recovery, it is important to characterize the pattern of brain activation during the reach task. METHODS:We evaluate...

journal_title：Restorative neurology and neuroscience

authors： Daly JJ,Hrovat K,Holcomb J,Pundik S

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Accurate coil placement over a target area is critical during transcranial magnetic stimulation (TMS), as small deviations can alter testing outcomes. Accordingly, frameless stereotaxic systems (FSS) are recommended for reliable coil placement during TMS applications. However, FSS is not practical due to the co...

journal_title：Restorative neurology and neuroscience

authors： Washabaugh EP,Krishnan C

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Low-frequency rTMS can induce upregulation of excitability in the contralateral hemisphere by interhemispheric interaction. OBJECTIVE:The aim of this study was to compare the effects of interhemispheric modulation on hemodynamic changes after applying low-frequency rTMS over the anatomical hand knob (HK) an...

journal_title：Restorative neurology and neuroscience

authors： Kim J,Kim H,Lee J,Lee HJ,Na Y,Chang WH,Kim YH

更新日期：2020-01-01 00:00:00

abstract：PURPOSE:We wished to evaluate the efficacy of vision restoration therapy (VRT) in patients with post-chiasmatic brain damage using different functional perimetric tests. These were compared with measures of subjective vision and reaction time. METHODS:An open trial was conducted with hemianopia/scotoma (n=16) patients...

journal_title：Restorative neurology and neuroscience

authors： Sabel BA,Kenkel S,Kasten E

更新日期：2004-01-01 00:00:00

abstract：:Many ocular diseases (such as glaucoma, diabetic retinopathy, age-related macular degeneration, and traumatic eye injuries) can result in the degeneration of retinal cells and the subsequent loss of vision. Some kinds of treatments, such as drugs, stem cell transplantation and surgery are reported to be effective in c...

journal_title：Restorative neurology and neuroscience

authors： Li HY,Rong SS,Hong X,Guo R,Yang FZ,Liang YY,Li A,So KF

更新日期：2019-01-01 00:00:00

abstract：:In the present study, we have developed an animal model for central nervous system (CNS) damage using the graded crush injury of the adult rat optic nerve. This injury model has the following characteristics: (a) the injuries are reproducible; (b) the injuries can be created with controlled severity; and (c) variation...

journal_title：Restorative neurology and neuroscience

authors： Duvdevani R,Rosner M,Belkin M,Sautter J,Sabel BA,Schwartz M

更新日期：1990-01-01 00:00:00

abstract：:Administration of gangliosides accelerates recovery of function after entorhinal cortex lesions on open field activity and learned spatial alternation tasks. In the present study, we examined whether GM1 ganglioside might enhance recovery from bilateral entorhinal cortex lesions on a differential reinforcement of low-...

journal_title：Restorative neurology and neuroscience

authors： Ramirez JJ,MacDonald K,Mañibo J,Payne J,Tuite C

更新日期：1998-01-01 00:00:00

abstract：PURPOSE:The primary somatosensory cortex (S1) is somatotopically reorganized after limb amputation. The duration of the amputation, the intensity of phantom limb pain but also a multifactoral model of altered cerebral input have been discussed to be associated with cortical changes. Patients with finger amputation rare...

journal_title：Restorative neurology and neuroscience

authors： Oelschläger M,Pfannmöller J,Langner I,Lotze M

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:A realistic body representation needs to be constantly updated. In case of physiological modifications, body representations integrate information coming from different sensory sources, including the sense of touch. Previous studies described transient modifications of these representations following illusory d...

journal_title：Restorative neurology and neuroscience

authors： Cimmino RL,Spitoni G,Serino A,Antonucci G,Catagni M,Camagni M,Haggard P,Pizzamiglio L

更新日期：2013-01-01 00:00:00

abstract：:The hypothesis that a destabilization of mitochondrial function during neuronal exposure to excitatory amino acids may be involved in the mechanism of neuronal death was examined. The mitochondrial membrane potential (Delta(psi)m) and the cytoplasmic Ca2+ concentration ([Ca2+]c) were monitored simultaneously in single...

journal_title：Restorative neurology and neuroscience

authors： Kiedrowski L

更新日期：1998-06-01 00:00:00

abstract：:PURPOSE: Until recently, there has been a limited amount of research comparing functional and anatomical recovery following nerve injury. Previous studies emphasizing anatomical recovery (such as axonal number) have shown that testosterone promotes regeneration in crushed and transected nerves. The purpose of this stu...

journal_title：Restorative neurology and neuroscience

authors： Swallow RK,Leiser MR,Fink BE,Sauer C,Nicklous DM,Hoffman JR

更新日期：1999-01-01 00:00:00

abstract：:Vestibular habituation was studied in normal subjects and in patients with cerebellar disease using a stimulation paradigm proposed in this paper. Six caloric stimuli were repeated daily in the same ear during six days and electronystagmographic responses at the beginning and the end of that period were compared. The ...

journal_title：Restorative neurology and neuroscience

authors： Suarez H,Caffa C,Macadar O

更新日期：1992-01-01 00:00:00

abstract：:A long-term goal in motor rehabilitation is that treatment is not selected on the basis of 'schools of thought', but rather, based on knowledge about efficacy and effectiveness of specific interventions for specific situations (e.g. functional syndromes). Motor dysfunction after stroke or TBI can be caused by many dif...

journal_title：Restorative neurology and neuroscience

authors： Platz T,Hesse S,Mauritz KH

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:After stroke, the learned non-use of a paretic arm is a major obstacle to the improvement of hand function. OBJECTIVE:We examined whether patients with a central paresis could profit from applying the self-regulation strategy of making if-then plans that specify situational triggers to using the paretic arm...

journal_title：Restorative neurology and neuroscience

authors： Marquardt MK,Cohen AL,Gollwitzer PM,Gilbert SJ,Dettmers C

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Robot-assisted gait training (RAGT) is widely used in children with cerebral palsy (CP), but information about optimal intervention frequency and duration is still lacking and the current evidence about effect of RAGT on motor endurance and fitness is very preliminary. OBJECTIVE:To investigate the effect of...

journal_title：Restorative neurology and neuroscience

authors： Digiacomo F,Tamburin S,Tebaldi S,Pezzani M,Tagliafierro M,Casale R,Bartolo M

更新日期：2019-01-01 00:00:00

abstract：PURPOSE:To determine how age at the time of left middle cerebral artery stroke affects language lateralization in a combined sample of subjects with perinatal, childhood, and adult stroke. METHODS:19 participants who had perinatal stroke (<1 month of age), 32 with later stroke, and 51 sex-/age-matched healthy controls...

journal_title：Restorative neurology and neuroscience

authors： Szaflarski JP,Allendorfer JB,Byars AW,Vannest J,Dietz A,Hernando KA,Holland SK

更新日期：2014-01-01 00:00:00

abstract：:Portions of 1 cm length of the sensory radial nerve from the cat forelimb were used to replace an excised portion of the dorsal columns in the upper lumbar spinal cord. Observations were made on the clinical recovery of the animals, and cine recordings were made of their ability to traverse a horizontal ladder 5 month...

journal_title：Restorative neurology and neuroscience

authors： Wilson DH

更新日期：1991-01-01 00:00:00

abstract：PURPOSE:The aim of the study was to examine if improvements of stimulus detection performance in visual field tests after intensive visual training of the visual field border zone in patients with visual field defects are associated with changes in self-reported vision- and health-related quality of life (QoL). METHOD...

journal_title：Restorative neurology and neuroscience

authors： Gall C,Mueller I,Gudlin J,Lindig A,Schlueter D,Jobke S,Franke GH,Sabel BA

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:The dopamine system plays a key role in motor learning and neuroplasticity. Several studies have studied the efficacy of dopaminergic drugs in enhancing motor recovery after stroke, but the effects are controversial. Although genetic variations in plasticity-related genes influence each individual's capacity...

journal_title：Restorative neurology and neuroscience

authors： Kim BR,Kim HY,Chun YI,Yun YM,Kim H,Choi DH,Lee J

更新日期：2016-11-22 00:00:00

abstract：OBJECTIVE:To report the safety and efficacy of a novel therapeutic trial with umbilical cord blood (UCB) and concomitant recombinant human erythropoietin (rhEPO), which was tried for three cases of severe traumatic brain injury (TBI) in rehabilitation. DESIGN:Case series. SETTING:University hospital setting. PARTICI...

journal_title：Restorative neurology and neuroscience

authors： Min K,Song J,Lee JH,Kang MS,Jang SJ,Kim SH,Kim M

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:There is considerable variability in the extent and nature of the glial response to injury and neurodegeneration. Transplantation of fetal cortical tissue onto the brain of neonatal host rats or mice results in region-specific changes dependent on where the fetal tissue is placed. These changes include chronic ...

journal_title：Restorative neurology and neuroscience

authors： Bates KA,Drummond ES,Cozens GS,Harvey AR

更新日期：2016-01-01 00:00:00

abstract：:The authors used different kinds of peripheral nerve grafts to reconstruct a terminal branch of the brachial plexus (the median nerve) gap of adult Sprague-Dawley rats, including fresh or frozen autografts and allografts from Norway rats. They also performed acellular allograft repopulation by autogenous Schwann cells...

journal_title：Restorative neurology and neuroscience

authors： Accioli-De-Vaconcellos ZA,Kassar-Duchossoy L,Mira JC

更新日期：1999-01-01 00:00:00

abstract：:Over the past few decades astrocytes have emerged from being considered simple packing tissue in the brain to become major players in the development, survival and functioning of central nervous system (CNS) neurons. As the influence that astrocytes (and the various molecules they produce) have on the development of C...

journal_title：Restorative neurology and neuroscience

authors： Gates MA,Dunnett SB

更新日期：2001-01-01 00:00:00

abstract：PURPOSE:This study investigated whether enrichment improves hindlimb movement following complete spinal cord transection and transplantation of olfactory ensheathing glia (OEG), with or without a Schwann cell (SC) bridge. METHODS:Motor activity was encouraged through provision of motor enrichment housing (MEH); a mult...

journal_title：Restorative neurology and neuroscience

authors： Moon LD,Leasure JL,Gage FH,Bunge MB

更新日期：2006-01-01 00:00:00

abstract：PURPOSE:The present work compared the behavioral outcomes of ACCS therapy delivered either intravenously (i.v.) or intracerebroventricularly (i.c.v.) after penetrating ballistic-like brain injury (PBBI). Histological markers for neuroinflammation and neurodegeneration were employed to investigate the potential therapeu...

journal_title：Restorative neurology and neuroscience

authors： Deng-Bryant Y,Readnower RD,Leung LY,Cunningham TL,Shear DA,Tortella FC

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:Study the effect of peripheral nerve extracts and BDNF on retinal ganglion cell (RGC) regeneration in adult rats. METHODS:Postmicrosomal fractions were obtained from 7-day, predegenerated, as well as non-predegenerated peripheral adult rats nerves. Autologous connective tissue chambers filled with fibrin were ...

journal_title：Restorative neurology and neuroscience

authors： Swiech-Sabuda E,Gołka B,Kotulska K,Larysz-Brysz M,Górka D,Gołka D,Marcol W,Lewin-Kowalik J

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Focal dystonia in musicians (MD) is a task-specific movement disorder with a loss of voluntary motor control during instrumental playing. Defective inhibition on different levels of the central nervous system is involved in the pathophysiology. Sensorimotor retraining is a therapeutic approach to MD and aims...

journal_title：Restorative neurology and neuroscience

authors： Buttkus F,Baur V,Jabusch HC,de la Cruz Gomez-Pellin M,Paulus W,Nitsche MA,Altenmüller E

更新日期：2011-01-01 00:00:00