Ultrastructural changes accompanying the mechanical deformation of bone tissue: a Raman imaging study.

abstract：:Plasma osteocalcin (BGP), growth hormone (GH), and somatomedin C(SmC) were measured in 12 patients with acromegaly [7 clinically active (aA), 5 cured (cA)] and 9 control subjects (C). Basal plasma values for the three parameters were higher in aA than in C and in cA. No significant difference was found between cA and ...

journal_title：Calcified tissue international

authors： de la Piedra C,Larrañaga J,Castro N,Horcajada C,Rapado A,Herrera Pombo JL,Carbó E

更新日期：1988-07-01 00:00:00

abstract：:Although several observational studies have demonstrated an association between vitamin K status and bone mineral density (BMD) in postmenopausal women, no placebo-controlled intervention trials of the effect of vitamin K1 supplementation on bone loss have been reported thus far. In the trial presented here we have in...

journal_title：Calcified tissue international

authors： Braam LA,Knapen MH,Geusens P,Brouns F,Hamulyák K,Gerichhausen MJ,Vermeer C

更新日期：2003-07-01 00:00:00

abstract：:We compared indices of three-dimensional microstructure of iliac trabecular bone between 26 patients with vertebral compression fractures due to postmenopausal osteoporosis and 24 control subjects without vertebral fracture, who were matched for age, sex, race, menopausal status, and several densitometric and histolog...

journal_title：Calcified tissue international

authors： Kleerekoper M,Villanueva AR,Stanciu J,Rao DS,Parfitt AM

更新日期：1985-12-01 00:00:00

abstract：:Atomic force microscopy (AFM) was used to obtain three-dimensional images of isolated mineralites extracted from young postnatal bovine bone. The mean mineralite size is 9 nm x 6 nm x 2.0 nm, significantly shorter and thicker than the mineralites of mature bovine bone measured by the same technique. Mineralites of the...

journal_title：Calcified tissue international

authors： Tong W,Glimcher MJ,Katz JL,Kuhn L,Eppell SJ

更新日期：2003-05-01 00:00:00

abstract：:The aim of this work was to explore the reduction of fluoride concentrations in the skeleton after stopping experimental fluoride administration. Fluoride was administered to the rats at varying doses (0, 50, 100 ppm in drinking water) and for different lengths of time (4, 13, 25 weeks). A series of fluoride concentra...

journal_title：Calcified tissue international

authors： Li J,Nakagaki H,Kato K,Tsuboi S,Kato S,Morita I,Ohno N,Kameyama Y,Chen R,Robinson C

更新日期：1995-04-01 00:00:00

abstract：:Syndesmophyte occurrence and axial bone loss were investigated in the heterozygous Tg187 tumor necrosis factor (TNF) transgenic mouse model (Tg-huTNF) of arthritis. Female and male Tg-huTNF mice were compared to wild-type mice (WT) at 2, 4, 6, 8, and 10 weeks. Syndesmophytes, intervertebral disc space, osteoclasts, os...

journal_title：Calcified tissue international

authors： Courbon G,Flammier S,Laroche N,Vico L,Marotte H,Coury F

更新日期：2017-06-01 00:00:00

abstract：:The binding of prostaglandin E2 (PGE2) to bone cells was studied to provide direct evidence for the existence of specific receptors in bone. Bone cells were isolated by collagenase digestion of fetal and newborn rat calvaria. Isolated cells were incubated with 3H-PGE2 and collected on Millipore filters. Specific bindi...

journal_title：Calcified tissue international

authors： Dziak RM,Hurd D,Miyasaki KT,Brown M,Weinfeld N,Hausmann E

更新日期：1983-01-01 00:00:00

abstract：:In order to investigate the pathogenesis of ossification of the posterior longitudinal ligament (OPLL) of the spine, we examined the distribution of insulin-like growth factor I (IGF-I) in the posterior longitudinal ligaments of OPLL patients, and analyzed the effects of IGF-I on the cultured spinal ligament cells. Fo...

journal_title：Calcified tissue international

authors： Goto K,Yamazaki M,Tagawa M,Goto S,Kon T,Moriya H,Fujimura S

更新日期：1998-02-01 00:00:00

abstract：:At 4 and 24 hours after injection of (35S)sulfate, there were 22-67% fewer silver grains on conventionally fixed sections than on sections fixed by cryotechniques. Differences were smaller when (3H) glucosamine was chosen as precursor. The number of silver grains increased between 4 and 24 hours in predentine and in a...

journal_title：Calcified tissue international

authors： Goldberg M,Escaig F

更新日期：1985-09-01 00:00:00

abstract：:This study examined effects of bone bonding and nonbonding implants on parameters associated with matrix vesicle-mediated primary bone formation, matrix vesicle alkaline phosphatase and phospholipase A2 specific activities, and phosphatidylserine content. Tibia marrow ablation followed by implantation of KG-Cera, Mina...

journal_title：Calcified tissue international

authors： Schwartz Z,Swain LD,Marshall T,Sela J,Gross U,Amir D,Muller-Mai C,Boyan BD

更新日期：1992-12-01 00:00:00

abstract：:Recommendations from the FNIH Sarcopenia Project are that appendicular lean mass (ALM, kg) adjusted for body mass index (BMI, kg/m2) be used for identifying low lean mass, with ALM/BMI cutpoints of < 0.789 m2 for men and < 0.512 m2 for women. We report normative ALM/BMI values for Australian adults, and compare the pe...

journal_title：Calcified tissue international

authors： Pasco JA,Holloway-Kew KL,Tembo MC,Sui SX,Anderson KB,Rufus-Membere P,Hyde NK,Williams LJ,Kotowicz MA

更新日期：2019-04-01 00:00:00

abstract：:During mechanical unloading, endothelial cells reduce osteogenesis and increase bone resorption. Here we describe the feedback response of endothelial cells to unloaded osteoblasts. Primary endothelial cells, ex vivo mouse aortic rings and chicken egg yolk membranes were incubated with conditioned medium from mouse pr...

journal_title：Calcified tissue international

authors： Veeriah V,Paone R,Chatterjee S,Teti A,Capulli M

更新日期：2019-03-01 00:00:00

abstract：:Disturbances in mineral and bone metabolism are common in patients with chronic kidney disease (CKD), especially those undergoing dialysis. Renal osteodystrophy, which describes an alteration of bone morphology, is an important component of this systemic disorder and may explain the elevated risk of fracture which adv...

journal_title：Calcified tissue international

authors： Komaba H,Ketteler M,Cunningham J,Fukagawa M

更新日期：2021-01-02 00:00:00

abstract：:Radioiodination of synthetic human 37-49 osteocalcin requires optimal labeling conditions in order to obtain a maximum of mono- and di-iodinated tracer with little contamination by tri- and tetra-iodinated products or "radio-damage." The antibody raised against osteocalcin(h37-49) had the highest affinity for the C-te...

journal_title：Calcified tissue international

authors： Jüppner H,Schettler T,Giebel G,Wenner S,Hesch RD

更新日期：1986-11-01 00:00:00

abstract：:As tobacco smoking has been identified as a risk factor in the development of osteoporosis, possible deleterious effects of nicotine inhalation on bone mineral density (BMD) and mechanical properties of the femur in female rats were studied. Female Sprague Dawley rats were exposed to nicotine vapour 20 hours a day 5 d...

journal_title：Calcified tissue international

authors： Syversen U,Nordsletten L,Falch JA,Madsen JE,Nilsen OG,Waldum HL

更新日期：1999-09-01 00:00:00

abstract：:Although treatment with intranasal salmon calcitonin (sCT) has been shown to effectively inhibit postmenopausal bone loss, there is still controversy over both timing and the duration of its application. In an open prospective study, we therefore assessed the effect of shortterm intranasal sCT on postmenopausal bone t...

journal_title：Calcified tissue international

authors： Kraenzlin ME,Seibel MJ,Trechsel U,Boerlin V,Azria M,Kraenzlin CA,Haas HG

更新日期：1996-04-01 00:00:00

abstract：:Bone mass increases steadily until age 20-30 years, when peak bone mass (PBM) is acquired. Nutrition plays a critical role in achievement of the optimal genetically programmed PBM, with reduction in the risk of osteoporosis later in life. Intake of nutrients can be estimated through the use of various tools; typically...

journal_title：Calcified tissue international

authors： Pampaloni B,Bartolini E,Barbieri M,Piscitelli P,Di Tanna GL,Giolli L,Brandi ML

更新日期：2013-07-01 00:00:00

abstract：:Alkaptonuria (AKU) is characterised by increased circulating homogentisic acid and deposition of ochronotic pigment in collagen-rich connective tissues (ochronosis), stiffening the tissue. This process over many years leads to a painful and severe osteoarthropathy, particularly affecting the cartilage of the spine and...

journal_title：Calcified tissue international

authors： Hughes JH,Keenan CM,Sutherland H,Edwards HR,Wilson PJM,Ranganath LR,Jarvis JC,Bou-Gharios G,Gallagher JA

更新日期：2021-02-01 00:00:00

abstract：:We studied the most complete skeletons found in an excavation from the 14th and 15th century in central Stockholm. One hundred eighty-seven were from men and 156 from women: 241 individuals were estimated to be between 20 and 39 and 102 between 40 and 59 years old at death. We examined the bones radiographically and b...

journal_title：Calcified tissue international

authors： Ekenman I,Eriksson SA,Lindgren JU

更新日期：1995-05-01 00:00:00

abstract：:Proline biosynthetic and degradative enzymes are unevenly distributed in differentiated mammalian tissues. Activities of the synthetic enzymes are relatively high in collagenous tissues, whereas activities of the degradative enzymes are high in noncollagenous tissues. In order to further characterize tissue-specific p...

journal_title：Calcified tissue international

authors： Smith RJ,Reddi AH,Phang JM

更新日期：1979-07-03 00:00:00

abstract：:This manuscript discusses mineral and bone disorders of chronic kidney disease (MBD-CKD) in pediatric patients with special emphasis on the underlying pathophysiology, the causes and clinical profile of growth retardation, the alterations in the growth plate, the strategies to optimize growth and the medical recommend...

journal_title：Calcified tissue international

authors： Santos F,Díaz-Anadón L,Ordóñez FA,Haffner D

更新日期：2021-01-16 00:00:00

abstract：:Raman spectroscopy has been used to demonstrate, for the first time, that calcium mineralization in the core of the major lateral teeth of the chiton Acanthopleura echinata takes place as an ordered process, with crystalline carbonated apatite being the first mineral deposited. Deposition begins at the top of the toot...

journal_title：Calcified tissue international

authors： Lee AP,Brooker LR,Macey DJ,van Bronswijk W,Webb J

更新日期：2000-11-01 00:00:00

abstract：:The goal of this study was to find out if bone can recover after long-term administration of bisphosphonate. Disodium pamidronate (APD) was given orally by gavage to mature beagle dogs at doses of 0, 2.5, 12.5, and 25 mg/kg/day for 1 year (0.1% concentration) and the animals were allowed to recover for another year. A...

journal_title：Calcified tissue international

authors： Grynpas MD,Kasra M,Dumitriu M,Nespeca R,Very JM,Mertz BP

更新日期：1994-10-01 00:00:00

abstract：:This study sought to confirm that osteoblasts of C3H/HeJ (C3H) mice, which have higher differentiation status and bone-forming ability compared to C57BL/6J (B6) osteoblasts, also have a lower apoptosis level and to test whether the higher differentiation status and bone-forming ability of C3H osteoblasts were related ...

journal_title：Calcified tissue international

authors： Sheng MH,Lau KH,Mohan S,Baylink DJ,Wergedal JE

更新日期：2006-05-01 00:00:00

abstract：:The purpose of this study was to determine whether human parathyroid hormone (h-PTH) enhances trabecular bone mass and connectivities that were reduced by streptozotocin (STZ)-induced diabetes in rats. Seven-month-old female Wistar rats were injected with STZ or its vehicle intraperitoneally. All vehicle-injected norm...

journal_title：Calcified tissue international

authors： Tsuchida T,Sato K,Miyakoshi N,Abe T,Kudo T,Tamura Y,Kasukawa Y,Suzuki K

更新日期：2000-03-01 00:00:00

abstract：:Quantitative ultrasound measurement (QUS) and bone mineral density (BMD) have each been shown to predict fracture risk in women. The present study examined whether a combination of QUS and BMD could improve the predictive accuracy of fracture risk. This is a population-based prospective study which involved 454 women ...

journal_title：Calcified tissue international

authors： Chan MY,Nguyen ND,Center JR,Eisman JA,Nguyen TV

更新日期：2012-02-01 00:00:00

abstract：:The discriminating ability and relevance of clinical risk factors, quantitative ultrasound (QUS) variables, X-ray-based bone mineral density (BMD) and hip axis length (HAL) measurements to evaluate the risk of osteoporotic fracture in elderly Brazilian women were examined in this study. QUS at the calcaneus (Achilles ...

journal_title：Calcified tissue international

authors： Pinheiro MM,Castro CH,Frisoli A Jr,Szejnfeld VL

更新日期：2003-12-01 00:00:00

abstract：:Calcaneus bone mineral density (BMD) of 738 Japanese women (605 healthy and 133 with osteoporosis) was measured using single X-ray absorptiometry (SXA). A reference range of calcaneus BMD values for healthy Japanese women was established and the usefulness of this method for screening and diagnosis of osteoporosis was...

journal_title：Calcified tissue international

authors： Sekioka Y,Kushida K,Yamazaki K,Inoue T

更新日期：1999-08-01 00:00:00

abstract：:To assess the reductions in bone mass, strength, and turnover in adjuvant-induced arthritic rats and to examine the effect of a new benzamide compound, DU-6712, on these parameters, a 28-day dosing experiment was performed using 8-week-old female Lewis rats. Arthritis was induced by injecting the adjuvant into the hin...

journal_title：Calcified tissue international

authors： Uchiyama Y,Takamori H,Miyama K,Takano E,Nakajima H,Sato T,Nakamura T

更新日期：1998-06-01 00:00:00

abstract：:Osteoporosis is commonly associated with estrogen deficiency. However, the mechanisms by which the lack of this hormone causes bone loss are poorly understood. The bone structure of the oral cavity seems to be affected by estrogen deficiency, since a delayed healing process after tooth extraction has been observed aft...

journal_title：Calcified tissue international

authors： Zecchin KG,Pereira MC,Coletta RD,Graner E,Jorge J

更新日期：2005-02-01 00:00:00