Abstract：
:We used fMRI to investigate how moment-to-moment neural activity contributes to success or failure on individual trials of a visual working memory (WM) task. We found that different nodes of a distributed cortical network were activated to a greater extent for correct compared to incorrect trials during stimulus encoding, memory maintenance during delays, and at test. A logistic regression analysis revealed that the fMRI signal amplitude during the delay interval in a network of frontoparietal regions predicted successful performance on a trial-by-trial basis. Differential delay activity occurred even for only those trials in which BOLD activity during encoding was strong, demonstrating that it was not a simple consequence of effective versus ineffective encoding. Our results indicate that accurate memory depends on strong sustained signals that span the delay interval of WM tasks.
journal_name
Neuronjournal_title
Neuronauthors
Pessoa L,Gutierrez E,Bandettini P,Ungerleider Ldoi
10.1016/s0896-6273(02)00817-6subject
Has Abstractpub_date
2002-08-29 00:00:00pages
975-87issue
5eissn
0896-6273issn
1097-4199pii
S0896627302008176journal_volume
35pub_type
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