A novel, anchorless streptococcal surface protein that binds to human immunoglobulins.

abstract：:The exposure of organ cultured pineal glands of Syrian hamsters to forskolin, an adenylate cyclase activator, caused marked increases in serotonin N-acetyltransferase activity and melatonin content in a dose-related manner (1-100 microM) when glands were collected in the second half of the dark period. However, additi...

journal_title：Biochemical and biophysical research communications

authors： Santana C,Guerrero JM,Reiter RJ,Gonzalez-Brito A,Menendez-Pelaez A

更新日期：1988-08-30 00:00:00

abstract：:We have explored the mechanism by which an antifungal antibiotic, (S)-2-amino-4-oxo-5-hydroxypentanoic acid, RI-331, preferentially inhibits protein biosynthesis in Saccharomyces cerevisiae, by inhibiting the biosynthesis of the aspartate family of amino acids, methionine, isoleucine and threonine. This inhibition was...

journal_title：Biochemical and biophysical research communications

authors： Yamaki H,Yamaguchi M,Imamura H,Suzuki H,Nishimura T,Saito H,Yamaguchi H

更新日期：1990-04-30 00:00:00

abstract：:Lipases are widely present in various plants, animals and microorganisms, constituting a large category of enzymes. They have the ability to catalyze the cleavage of ester bonds. The lipase CinB from Enterobacter asburiae (E. asburiae) is an acetyl esterase. The primary amino acid sequence suggests that the EaCinB pro...

journal_title：Biochemical and biophysical research communications

authors： Shang F,Lan J,Liu W,Chen Y,Wang L,Zhao J,Chen J,Gao P,Ha NC,Quan C,Nam KH,Xu Y

更新日期：2019-11-05 00:00:00

abstract：:WRKY transcription factors are key regulators in regulating abiotic or biotic stress response in Arabidopsis. Previous studies showed that WRKY30 expression was induced by oxidative stress treatment, fungal elicitor, SA and ABA. However, functions of WRKY30 on viral defense are not well studied. Here, we found that Ar...

journal_title：Biochemical and biophysical research communications

authors： Zou L,Yang F,Ma Y,Wu Q,Yi K,Zhang D

更新日期：2019-09-10 00:00:00

abstract：:Ependymins, a family of extracellular glycoproteins of goldfish and mammalian brain, were shown to contain N-linked complex glycan chains. These glycoproteins reacted with a monoclonal antibody, HNK-1 which recognizes a membrane antigen on a subset of human lymphocytes, myelin-associated glycoprotein glycoprotein epit...

journal_title：Biochemical and biophysical research communications

authors： Shashoua VE,Daniel PF,Moore ME,Jungalwala FB

更新日期：1986-07-31 00:00:00

abstract：:Deoxynucleoside triphosphate concentrations in Chinese hamster ovary cell lines, CHO-K1 and Mut 8-16, were examined following exposure of cells to UV or dimethylsulfate. Marked decreases in dCTP were observed 2 hr after exposure to both mutagens. In contrast, dTTP concentrations increased with increased cell killing a...

journal_title：Biochemical and biophysical research communications

authors： Newman CN,Miller JH

更新日期：1983-07-18 00:00:00

abstract：:We found that pyridoxal phosphate shows considerable inhibition of cathepsins. CLIK-071, in which the phosphate ester of position 3 of pyridoxal phosphate was replaced by propionate, strongly inhibited cathepsin B. Three new types of synthetic pyridoxal propionate derivatives showing specific inhibition of cathepsin K...

journal_title：Biochemical and biophysical research communications

authors： Katunuma N,Matsui A,Inubushi T,Murata E,Kakegawa H,Ohba Y,Turk D,Turk V,Tada Y,Asao T

更新日期：2000-01-27 00:00:00

abstract：:Neurotensin (NT), a gastrointestinal (GI) hormone, binds its receptor (NTR) to stimulate proliferation of normal and neoplastic GI tissues; the molecular mechanisms remain largely undefined. Mitogen-activated protein kinases (MAPKs) are a family of intracellular kinases that transmit mitogenic signals by translocating...

journal_title：Biochemical and biophysical research communications

authors： Ehlers RA,Zhang Y,Hellmich MR,Evers BM

更新日期：2000-03-24 00:00:00

abstract：:The 100,000 x g supernatant of bovine heart has been chromatographed on DEAE-cellulose and the resultant fractions have been analyzed for both calcium binding activity and calmodulin activity. Of the four peaks of calcium binding activity detected by this procedure only a single peak (peak IV) was identified as calmod...

journal_title：Biochemical and biophysical research communications

authors： Waisman DM,Khanna NC,Tokuda M

更新日期：1986-09-14 00:00:00

abstract：:Rex-1 is a zinc finger-containing gene that is expressed in embryonal carcinoma (EC) cells and embryonic stem (ES) cells. Upon differentiation with retinoic acid (RA), transcription of the Rex-1 gene decreases rapidly. Analysis of the 5'-flanking region of the Rex-1 gene identified a consensus motif for the octamer fa...

journal_title：Biochemical and biophysical research communications

authors： Rosfjord E,Rizzino A

更新日期：1994-09-30 00:00:00

abstract：:We identified a DNA polymerase species in Drosophila melanogaster embryos, and purified it. This polymerase shared some common properties with DNA polymerase epsilon from mammals and yeast as follows; it has a preference for poly(dA)/oligo(dT) as a template/primer, it is highly processive in DNA synthesis, it co-fract...

journal_title：Biochemical and biophysical research communications

authors： Aoyagi N,Oshige M,Hirose F,Kuroda K,Matsukage A,Sakaguchi K

更新日期：1997-01-13 00:00:00

abstract：:Alzheimer's disease (AD) is characterized by the formation of extracellular amyloid plaques containing the amyloid β-protein (Aβ) within the parenchyma of the brain. Aβ42, which is 42 amino acids in length, is considered to be the key pathogenic factor in AD. Iron deposition is found abundantly in the amyloid plaques ...

journal_title：Biochemical and biophysical research communications

authors： Shen X,Liu J,Fujita Y,Liu S,Maeda T,Kikuchi K,Obara T,Takebe A,Sayama R,Takahashi T,Matsue A,Sera K,Michikawa M,Komano H,Zou K

更新日期：2019-05-14 00:00:00

abstract：:The rfp/ret transforming gene was generated by DNA rearrangement which occurred during transfection of NIH 3T3 cells. The amino-terminal half of Rfp with a RING finger motif was fused to the truncated Ret receptor tyrosine kinase, leading to a transforming sequence, Rfp/Ret. In the present study, to elucidate the impo...

journal_title：Biochemical and biophysical research communications

authors： Hasegawa N,Iwashita T,Asai N,Murakami H,Iwata Y,Isomura T,Goto H,Hayakawa T,Takahashi M

更新日期：1996-08-14 00:00:00

abstract：:We provide the first demonstration for a Na+/Ca2+ exchanger, NCX-1, in the osteoclast. We speculate that by using Na+ exchange, NCX-1 couples H+ extrusion with Ca2+ fluxes during bone resorption. Microspectrofluorimetry of fura-2-loaded osteoclasts revealed a rapid and sustained, but reversible, cytosolic Ca2+ elevati...

journal_title：Biochemical and biophysical research communications

authors： Moonga BS,Davidson R,Sun L,Adebanjo OA,Moser J,Abedin M,Zaidi N,Huang CL,Zaidi M

更新日期：2001-05-18 00:00:00

abstract：:Whether alcohol-induced heart failure is caused by a direct toxic effect of ethanol, metabolites, or whether it is a secondary result of neurohumoral, hormonal, or nutritional factors is not clear. To address this question a Langendorff retrograde coronary perfusion model of rat heart was used to study the effect of 0...

journal_title：Biochemical and biophysical research communications

authors： Jänkälä H,Eklund KK,Kokkonen JO,Kovanen PT,Linstedt KA,Härkönen M,Mäki T

更新日期：2001-02-23 00:00:00

abstract：:Purified fractions of glycosylated (pGPrl) and unglycosylated (pUGPrl) porcine prolactin were prepared by affinity chromatography on Concanavalin A-Sepharose. The relative binding activities of these two forms of prolactin for receptors from porcine mammary, adrenal cortex and rabbit mammary, as well as their Nb2 cell...

journal_title：Biochemical and biophysical research communications

authors： Atkinson PR,Seely JE,Klemcke HG,Hughes JP

更新日期：1988-09-30 00:00:00

abstract：:Oxygen glucose deprivation (OGD)/re-oxygenation (OGDR) induces severe injury to neuronal cells. The expression and potential function of NKILA (NF-κB Interacting LncRNA) in OGDR-treated neuronal cells were tested in this study. We show that OGDR induced NKILA upregulation to in-activate NF-κB signaling in SH-SY5Y cell...

journal_title：Biochemical and biophysical research communications

authors： Wang M,Jiang YM,Xia LY,Wang Y,Li WY,Jin T

更新日期：2018-09-18 00:00:00

abstract：:Resolvin E1 (RvE1; 5S, 12R, 18R-trihydroxyeicosapentaenoic acid) is an anti-inflammatory lipid mediator derived from the omega-3 fatty acid eicosapentaenoic acid (EPA). It has been recently shown that RvE1 is involved in the resolution of inflammation. However, it is not known whether RvE1 is involved in the resolutio...

journal_title：Biochemical and biophysical research communications

authors： Aoki H,Hisada T,Ishizuka T,Utsugi M,Kawata T,Shimizu Y,Okajima F,Dobashi K,Mori M

更新日期：2008-03-07 00:00:00

abstract：:Cell motility and cell stiffness are closely related to metastatic activity of cancer cells. (-)-Epigallocatechin gallate (EGCG) has been shown to inhibit spontaneous metastasis of melanoma cell line into the lungs of mice, so we studied the effects of EGCG on cell motility, cell stiffness, and expression of vimentin ...

journal_title：Biochemical and biophysical research communications

authors： Takahashi A,Watanabe T,Mondal A,Suzuki K,Kurusu-Kanno M,Li Z,Yamazaki T,Fujiki H,Suganuma M

更新日期：2014-01-03 00:00:00

abstract：:We examined the intracellular localization of the myosin binding subunit (MBS) of smooth muscle myosin phosphatase. In MDCK cells in a confluent monolayer of polarized epithelial sheet, MBS was concentrated to the cell-cell adhesion sites. Double-immunofluorescence analysis with anti-MBS and anti-beta-catenin antibodi...

journal_title：Biochemical and biophysical research communications

authors： Inagaki N,Nishizawa M,Ito M,Fujioka M,Nakano T,Tsujino S,Matsuzawa K,Kimura K,Kaibuchi K,Inagaki M

更新日期：1997-01-23 00:00:00

abstract：:We tested usefulness of a target enrichment system SureSelect, a comprehensive viral nucleic acid detection method, for rapid identification of viral pathogens in feces samples of cattle, pigs and goats. This system enriches nucleic acids of target viruses in clinical/field samples by using a library of biotinylated R...

journal_title：Biochemical and biophysical research communications

authors： Oba M,Tsuchiaka S,Omatsu T,Katayama Y,Otomaru K,Hirata T,Aoki H,Murata Y,Makino S,Nagai M,Mizutani T

更新日期：2018-01-08 00:00:00

abstract：:Parkinson's disease (PD) is neurodegenerative disease, featured by a loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc), characteristic motor symptoms and cognitive impairment. Development of effective therapeutic drugs for PD is necessary. In this study, we investigated the potential of Brucein...

journal_title：Biochemical and biophysical research communications

authors： Yang Y,Kong F,Ding Q,Cai Y,Hao Y,Tang B

更新日期：2020-06-11 00:00:00

abstract：:We have found that the alkyl-lysophospholipid 1-octadecyl-2-methyl-rac-glycero-3-phosphocholine (ET-18-OCH3) was able to induce apoptosis in human promyelocytic HL-60 leukemic cells, as evidenced by the internucleosomal degradation of the cellular DNA into the characteristic 180-200 bp DNA fragments. This effect was o...

journal_title：Biochemical and biophysical research communications

authors： Mollinedo F,Martínez-Dalmau R,Modolell M

更新日期：1993-04-30 00:00:00

abstract：:The interaction of transketolase with its acceptor substrate, ribose 5-phosphate, has been studied. The active centers of the enzyme were shown to be functionally nonequivalent with respect to ribose 5-phosphate binding. Under the conditions where only one out of the two active centers of transketolase is functional, ...

journal_title：Biochemical and biophysical research communications

authors： Yurshev VA,Sevostyanova IA,Solovjeva ON,Zabrodskaya SV,Kochetov GA

更新日期：2007-10-05 00:00:00

abstract：:Northern hybridization studies showed that the level of ovalbumin mRNA decreases in the oviduct of the Japanese quail after adulthood. In order to find out if this is due to changes in the conformation of the chromatin containing the promoter region of the gene, nuclei of the oviduct of young, adult and old birds were...

journal_title：Biochemical and biophysical research communications

authors： Upadhyay R,Gupta S,Kanungo MS

更新日期：1996-09-13 00:00:00

abstract：:A cDNA encoding the entire tau subunit of rabbit skeletal muscle phosphorylase kinase was reconstructed and inserted into a plasmid containing the Escherichia coli ptac promoter and a constructed plasmid containing the ptac promoter and bacterial chloramphenicol acetyl transferase (CAT) gene, respectively. A significa...

journal_title：Biochemical and biophysical research communications

authors： Chen LR,Yuan CJ,Somasekhar G,Wejksnora P,Peterson JE,Myers AM,Graves L,Cohen PT,da Cruz e Silva EF,Graves DJ

更新日期：1989-06-15 00:00:00

abstract：:The detergent (Triton X-100, 4°C)-resistant membrane (DRM)-associated membrane proteins stomatin, sorcin, and synexin (anexin VII) exposed on the cytoplasmic side of membrane were investigated for their lateral distribution in relation to induced ganglioside(M1) (GM1) raft patches in flat (discocytic) and curved (echi...

journal_title：Biochemical and biophysical research communications

authors： Mrówczyńska L,Salzer U,Perutková S,Iglič A,Hägerstrand H

更新日期：2010-10-22 00:00:00

abstract：:The refolding kinetics of cobrotoxin (CBTX), a small-molecular-weight ( approximately 7 kDa) all beta-sheet protein, has been monitored using a variety of biophysical techniques. The secondary structure formation and hydrophobic collapse occur as distinct events during the refolding of the protein. Complete secondary ...

journal_title：Biochemical and biophysical research communications

authors： Sivaraman T,Kumar TK,Tu YT,Wang W,Lin WY,Chen HM,Yu C

更新日期：1999-06-24 00:00:00

abstract：:Although GPRC5B and GPRC5C are categorized into the G protein-coupled receptor family C, including glutamate receptors, GABA receptors, and taste receptors, their physiological functions remain unknown. Since both receptors are expressed in the brain and evolutionarily conserved from fly to human, it is conceivable th...

journal_title：Biochemical and biophysical research communications

authors： Sano T,Kim YJ,Oshima E,Shimizu C,Kiyonari H,Abe T,Higashi H,Yamada K,Hirabayashi Y

更新日期：2011-09-02 00:00:00

abstract：:Iron overload, as a risk factor for osteoporosis, can result in the up-regulation of Hepcidin, and Hepcidin knockout mice display defects in their bone microarchitecture. However, the molecular and genetic mechanisms underlying Hepcidin deficiency-derived bone loss remain unclear. Here, we show that hepcidin knockdown...

journal_title：Biochemical and biophysical research communications

authors： Jiang Y,Yan Y,Wang X,Zhu G,Xu YJ

更新日期：2016-07-15 00:00:00