当前位置： SCI文献检索 > BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS期刊下所有文献 > Demonstration of glucuronic acid on brain glycoproteins which react with HNK-1 antibody.

Demonstration of glucuronic acid on brain glycoproteins which react with HNK-1 antibody.

Abstract：

:Ependymins, a family of extracellular glycoproteins of goldfish and mammalian brain, were shown to contain N-linked complex glycan chains. These glycoproteins reacted with a monoclonal antibody, HNK-1 which recognizes a membrane antigen on a subset of human lymphocytes, myelin-associated glycoprotein glycoprotein epitope reacting with HNK-1 antibody was previously shown to include a terminal 3-sulfoglucuronosyl residue present in certain glycolipids of the nervous tissue (Chou et al., Biochem. Biophys. Res. Commun. 1985, 128, 383-388). In this report, the presence of glucuronic acid in ependymins was demonstrated by gas-liquid chromatography and mass spectrometry. We suggest that a 3-sulfoglucuronosyl residue may be the common epitope on HNK-1-reactive glycoproteins.

journal_name

Biochem Biophys Res Commun

journal_title

Biochemical and biophysical research communications

authors

Shashoua VE,Daniel PF,Moore ME,Jungalwala FB

doi

10.1016/s0006-291x(86)80581-2

subject

Has Abstract

pub_date

1986-07-31 00:00:00

pages

902-9

issue

2

eissn

0006-291X

issn

1090-2104

pii

S0006-291X(86)80581-2

journal_volume

138

pub_type

杂志文章

相关文献

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS文献大全
  • Protective autophagy is involved in resistance towards MET inhibitors in human gastric adenocarcinoma cells.

    abstract：:MET, also known as hepatocyte growth factor receptor (HGFR), is a receptor tyrosine kinase with an important role, both in normal cellular function as well as in oncogenesis. In many cancer types, abnormal activation of MET is related to poor prognosis and various strategies to inhibit its function, including small mo...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2012.12.120

    authors： Humbert M,Medová M,Aebersold DM,Blaukat A,Bladt F,Fey MF,Zimmer Y,Tschan MP

    更新日期：2013-02-08 00:00:00

  • Biochemical thresholds for pathological presentation of ATP synthase deficiencies.

    abstract：:Mitochondrial ATP synthase is responsible for production of the majority of cellular ATP. Disorders of ATP synthase in humans can be caused by numerous mutations in both structural subunits and specific assembly factors. They are associated with variable pathogenicity and clinical phenotypes ranging from mild to the m...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2019.11.033

    authors： Nuskova H,Mikesova J,Efimova I,Pecinova A,Pecina P,Drahota Z,Houstek J,Mracek T

    更新日期：2020-01-22 00:00:00

  • Rearrangement of the p53 gene in human breast tumours.

    abstract：:Rearrangement of the p53 gene is frequent in virus transformed cell lines and in chronic myelogenous leukemia. It is a rare event in solid tumours and has been reported only in osteosarcomas. In this study we have examined rearrangement of the p53 gene in human breast tumours. We found rearrangement in 35% of the pati...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.8444

    authors： Nayak BK,Patnaik S,Das BR

    更新日期：1998-04-17 00:00:00

  • 2-((2-Pyridylmethyl)sulfinyl)benzimidazoles: acid sensitive suicide inhibitors of the proton transport system in the parietal cell.

    abstract：:2-((2-Pyridylmethyl)sulfinyl)benzimidazoles, selective inhibitors of the H+/K+-ATPase in the parietal cells of the stomach, have been investigated concerning their chemical behaviour in acidic medium. Protonation of the sulfoxide and subsequent elimination of water forms a sulfenium ion or a chemical equivalent thereo...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(85)91703-6

    authors： Rackur G,Bickel M,Fehlhaber HW,Herling A,Hitzel V,Lang HJ,Rösner M,Weyer R

    更新日期：1985-04-16 00:00:00

  • Growth inhibition of HL-60 cells by extracellular ATP: concentration-dependent involvement of a P2 receptor and adenosine generation.

    abstract：:A single addition of ATP (20-1000 microM) to cultures of HL-60 cells resulted here in permanent, Ca(2+)-independent inhibition of cellular proliferation, evident 48 h following treatment. Extracellular ATP (ATPo) was maximally effective at 250 microM giving 90 +/- 1.5% growth inhibition. Up to a concentration of 250 m...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1998.9329

    authors： Seetulsingh-Goorah SP,Stewart BW

    更新日期：1998-09-18 00:00:00

  • Identification of a novel determinant of glutathione affinity in dichloromethane dehalogenases/glutathione S-transferases.

    abstract：:Bacterial dichloromethane dehalogenases catalyze the glutathione-dependent hydrolysis of dichloromethane to formaldehyde and are members of the enzyme superfamily of glutathione S-transferases involved in the detoxification of electrophilic compounds. Numerous protein engineering studies have addressed questions perta...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1997.7309

    authors： Vuilleumier S,Sorribas H,Leisinger T

    更新日期：1997-09-18 00:00:00

  • MicroRNA-15b regulates cell cycle progression by targeting cyclins in glioma cells.

    abstract：:MicroRNAs (miRNAs) are non-protein-coding RNAs that function as post-transcriptional gene regulators. Recent evidence has shown that miRNA plays a pivotal role in the development of many cancers including glioma, a lethal brain cancer. We have recently compared the miRNA expression profiles between normal brain and gl...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.12.169

    authors： Xia H,Qi Y,Ng SS,Chen X,Chen S,Fang M,Li D,Zhao Y,Ge R,Li G,Chen Y,He ML,Kung HF,Lai L,Lin MC

    更新日期：2009-03-06 00:00:00

  • Expression and characterization of a fusion protein between the catalytic domain of poly(ADP-ribose) polymerase and the DNA binding domain of the glucocorticoid receptor.

    abstract：:A fusion protein comprising the DNA-binding region of the glucocorticoid receptor and the catalytic domain of poly(ADP-ribose) polymerase was constructed. This chimeric protein was expressed both in E. coli and in eukaryotic cells and was recognized by antibodies to both polymerase and the glucocorticoid receptor. Sim...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.2012

    authors： Rosenthal D,Hong T,Cherney B,Zhang S,Shima T,Danielsen M,Smulson M

    更新日期：1994-07-29 00:00:00

  • Cholestane-3β, 5α, 6β-triol suppresses neuronal hyperexcitability via binding to voltage-gated sodium channels.

    abstract：:Neuronal hyperexcitability is identified as a critical pathological basis of epileptic seizures. Cholestane-3β, 5α, 6β-triol (Triol) is a major metabolic oxysterol of cholesterol. Although its neuroprotective effect on ischemia-induced neuronal injury and negative modulation of voltage-gated sodium (Nav) channels were...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.01.004

    authors： Tang L,Yan M,Leng T,Yin W,Cai S,Duan S,Zhu W,Lin S,Huang J,Yan G,Zheng G,Chen Y

    更新日期：2018-01-29 00:00:00

  • Long noncoding RNA expression in dermal papilla cells contributes to hairy gene regulation.

    abstract：:Dermal papilla (DP) cells may be the source of dermal-derived signaling molecules involved in hair-follicle development and postnatal hair cycling. Early-passage DP cells can induce hair growth in vivo, but, on further culture, this ability is lost. The cellular mechanisms underlying the hair-follicle induction proper...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.09.119

    authors： Lin CM,Liu Y,Huang K,Chen XC,Cai BZ,Li HH,Yuan YP,Zhang H,Li Y

    更新日期：2014-10-24 00:00:00

  • Tyrosine phosphorylation and activation of mitogen-activated protein kinases by thrombin in human platelets: possible involvement in late arachidonic acid release.

    abstract：:Thrombin induced tyrosine phosphorylation of 41-kDa and 43-kDa mitogen-activated protein (MAP) kinases in human platelets which was detectable at 1 min and peaked at 2 min after thrombin stimulation as assessed by immunoprecipitation and immunoblotting. The kinase activity, measured by phosphorylation of myelin basic ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1994.1073

    authors： Nakashima S,Chatani Y,Nakamura M,Miyoshi N,Kohno M,Nozawa Y

    更新日期：1994-01-28 00:00:00

  • O-glycans and O-glycosylation sites of recombinant human GM-CSF derived from suspension-cultured rice cells, and their structural role.

    abstract：:Recombinant human GM-CSF (rhGM-CSF) from yeast has been clinically applied to immunosuppressed patients. The production of suspension-cultured rice-cell-derived rhGM-CSF (rrhGM-CSF), which has a longer blood clearance time and the same bioactivity as yeast-derived rhGM-CSF, and the analysis of its N-glycans have been ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2016.09.057

    authors： Kim J,Park H,Park BT,Hwang HS,Kim JI,Kim DK,Kim HH

    更新日期：2016-10-14 00:00:00

  • In boar sperm capacitation L-lactate and succinate, but not pyruvate and citrate, contribute to the mitochondrial membrane potential increase as monitored via safranine O fluorescence.

    abstract：:Having ascertained using JC-1 as a probe that, in distinction with the controls, during capacitation boar sperm maintains high mitochondrial membrane potential (ΔΨ), to gain some insight into the role of mitochondria in capacitation, we monitored ΔΨ generation due to externally added metabolites either in hypotonicall...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.04.128

    authors： Paventi G,Lessard C,Bailey JL,Passarella S

    更新日期：2015-07-03 00:00:00

  • Reduced expression of Tis7/IFRD1 protein in murine and human cystic fibrosis airway epithelial cell models homozygous for the F508del-CFTR mutation.

    abstract：:12-O-tetradecanoyl phorbol-13-acetate-induced sequence 7/interferon related development regulator 1 (Tis7/IFRD1) has been recently identified as a modifier gene in lung inflammatory disease severity in patients with cystic fibrosis (CF), based upon its capacity to regulate inflammatory activities in neutrophils. In CF...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2011.06.104

    authors： Blanchard E,Marie S,Riffault L,Bonora M,Tabary O,Clement A,Jacquot J

    更新日期：2011-08-05 00:00:00

  • Acetylcholine blocks Ca++-induced closure of outward K+ currents in isolated patches of canine atrial myocyte sarcolemma.

    abstract：:The patch clamp technique applied to canine atrial myocyte sarcolemma, showed that 2 types of K+ channels were differentially affected by Ach. The 2 channel types differed in conductance, responses to [Ca++], and sensitivity to membrane potential. Addition of Ach (10(-9) M to 10(-6) M) to pipette solutions increased o...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(87)91519-1

    authors： Bubien JK,Woods WT Jr

    更新日期：1987-02-13 00:00:00

  • The RB/E2F pathway and regulation of RNA processing.

    abstract：:The retinoblastoma tumor suppressor protein (RB) is inactivated in a majority of cancers. RB restricts cell proliferation by inhibiting the E2F family of transcription factors. The current model for RB/E2F function describes its role in regulating transcription at gene promoters. Whether the RB or E2F proteins might p...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章,评审

    doi：10.1016/j.bbrc.2009.04.107

    authors： Ahlander J,Bosco G

    更新日期：2009-07-03 00:00:00

  • High- and low-affinity CCKA receptor states mediate specific growth inhibitory effects on CHO cells.

    abstract：:To relate specific effects on growth and transformation to activation of specific affinity states of the CCKA receptor stably expressed in CHO cells we compared responses to the CCK analogues JMV-180 and CCK8. CCK8 led to an inhibition of both cell proliferation and transformation. Effects on proliferation were indica...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1995.2096

    authors： Detjen K,Tseng MJ,Logsdon CD

    更新日期：1995-08-04 00:00:00

  • Phospholipase D1 decreases type I collagen levels in hepatic stellate cells via induction of autophagy.

    abstract：:Hepatic stellate cells (HSCs) are major players in liver fibrogenesis. Accumulating evidence shows that suppression of autophagy plays an important role in the development and progression of liver disease. Phospholipase D1 (PLD1), which catalyzes the hydrolysis of phosphatidylcholine to yield phosphatidic acid (PA) an...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2014.04.149

    authors： Seo HY,Jang BK,Jung YA,Lee EJ,Kim HS,Jeon JH,Kim JG,Lee IK,Kim MK,Park KG

    更新日期：2014-06-20 00:00:00

  • Implication of pH in the catalytic properties of anthrax lethal factor.

    abstract：:The anthrax lethal factor (LF) is a Zn(2+)-endopeptidase specific for mitogen-activated protein kinase kinases (MAPKKs), which are cleaved within their N-terminal region. Much line of effort was carried out to elucidate the catalytic activity of LF for designing the inhibitor and to understand the cellular mechanism o...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2003.11.110

    authors： Kim J,Chai YG,Yoon MY

    更新日期：2004-01-02 00:00:00

  • Analysis of cardiomyocyte movement in the developing murine heart.

    abstract：:The precise assemblage of several types of cardiac precursors controls heart organogenesis. The cardiac precursors show dynamic movement during early development and then form the complicated heart structure. However, cardiomyocyte movements inside the newly organized mammalian heart remain unclear. We previously esta...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2015.07.036

    authors： Hashimoto H,Yuasa S,Tabata H,Tohyama S,Seki T,Egashira T,Hayashiji N,Hattori F,Kusumoto D,Kunitomi A,Takei M,Kashimura S,Yozu G,Shimojima M,Motoda C,Muraoka N,Nakajima K,Sakaue-Sawano A,Miyawaki A,Fukuda K

    更新日期：2015-09-04 00:00:00

  • Phorbol ester regulation of the human gamma-glutamyltransferase gene promoter.

    abstract：:In the present study the molecular mechanisms underlying tetradecanoylphorbol-13-acetate (TPA) mediated regulation of the human gamma-glutamyltransferase (GGT) gene were examined. TPA challenge of HeLa cells resulted in an increase of GGT mRNA and enzyme activity. Deletion analysis of the promoter revealed that the -3...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2003.11.121

    authors： Daubeuf S,Duvoix A,Wellman-Rousseau M,Diederich M,Visvikis A

    更新日期：2004-01-09 00:00:00

  • Specific derivatization of the active site tyrosine in dUTPase perturbs ligand binding to the active site.

    abstract：:Selective modification of one (of three) tyrosine residue per enzyme monomer leads to inactivation of dUTPase of the retrovirus equine infectious anemia virus (EIAV). The substrate dUMP and the cofactor Mg2+ protect against inactivation and modification, in agreement with the study on E. coli dUTPase (Vertessy et al. ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1006/bbrc.1996.0226

    authors： Vertessy BG,Persson R,Rosengren AM,Zeppezauer M,Nyman PO

    更新日期：1996-02-15 00:00:00

  • The nuclear receptor and clock gene REV-ERBα regulates cigarette smoke-induced lung inflammation.

    abstract：:REV-ERBα is a nuclear heme receptor, transcriptional repressor and critical component of the molecular clock that drives daily rhythms of metabolism. Evidence reveals that REV-ERBα also plays an important regulatory role in clock-dependent lung physiology and inflammatory responses. We hypothesize that cigarette smoke...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2017.09.157

    authors： Sundar IK,Rashid K,Sellix MT,Rahman I

    更新日期：2017-12-02 00:00:00

  • Effect of aphidicolin on the elongation step of adenovirus DNA replication in vitro.

    abstract：:Adenovirus DNA synthesis carried out in vitro was inhibited by the aphidicolin. However, 30% of the DNA synthesis was resistant to aphidicolin even at a concentration of 200 micrograms/ml. When the distribution patterns of the radioactivity of the products synthesized in the presence of 50 micrograms/ml of the drug wa...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(83)90435-7

    authors： Ariga H

    更新日期：1983-05-31 00:00:00

  • Synthesis of a nonreducible cyclic analog of somatostatin having only growth hormone release inhibiting activity.

    abstract：:A nonreducible cyclic analog of somatostatin (SRIF) was prepared by a combination of solid phase and solution peptide synthesis. The compound, gamma-Abu-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Asp-OH, was tested for its effect on the release of growth hormone, glucagon and insulin in rats. It significantly suppressed ...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(76)90208-4

    authors： Garsky VM,Clark DE,Grant NH

    更新日期：1976-12-20 00:00:00

  • Resolvin E1 dampens airway inflammation and hyperresponsiveness in a murine model of asthma.

    abstract：:Resolvin E1 (RvE1; 5S, 12R, 18R-trihydroxyeicosapentaenoic acid) is an anti-inflammatory lipid mediator derived from the omega-3 fatty acid eicosapentaenoic acid (EPA). It has been recently shown that RvE1 is involved in the resolution of inflammation. However, it is not known whether RvE1 is involved in the resolutio...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2008.01.012

    authors： Aoki H,Hisada T,Ishizuka T,Utsugi M,Kawata T,Shimizu Y,Okajima F,Dobashi K,Mori M

    更新日期：2008-03-07 00:00:00

  • Does intracellular histamine mediate mast cell histamine release?

    abstract：:Previously, we demonstrated that through binding a novel intracellular receptor of microM affinity (HIC), histamine mediates, and the HIC antagonist N,N-diethyl-2-[4-(phenylmethyl)phenoxy]ethanamine. HCl (DPPE) inhibits, platelet aggregation and serotonin granule secretion; the latter response is dependent upon the sa...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/0006-291x(90)92077-d

    authors： Brandes LJ,Sukhu B,Bogdanovic RP

    更新日期：1990-03-16 00:00:00

  • Activation of calcium-sensing receptor-mediated autophagy in angiotensinII-induced cardiac fibrosis in vitro.

    abstract：:Cardiac fibrosis is one of the primary mechanisms of ventricular remodeling, and there is no effective method for reversal. Activation of calcium sensing receptor (CaSR) has been reported to be involved in the development of myocardial fibrosis, but the molecular mechanism for CaSR activation has not yet been clarifie...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2018.02.098

    authors： Chi J,Wang L,Zhang X,Fu Y,Liu Y,Chen W,Liu W,Shi Z,Yin X

    更新日期：2018-03-04 00:00:00

  • In vivo 13C nuclear magnetic resonance spectroscopy using a solenoid transmit/receiver coil.

    abstract：:Topical nuclear magnetic resonance spectroscopy (NMR) using a solenoid transmit/receiver coil has been used to monitor the kinetics of intragastric utilization of [1-13C] glucose in mice in vivo. Using a double-tuned solenoid coil, signal to noise response was excellent and the natural abundance in vivo 13C spectra ob...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/s0006-291x(84)80217-x

    authors： Field J,Irving MG,Brooks WM,Doddrell DM

    更新日期：1984-09-28 00:00:00

  • Involvement of Rabring7 in EGF receptor degradation as an E3 ligase.

    abstract：:Rab7, a member of the Rab family small G proteins, is involved in the late stage of the endocytic pathway. We previously identified a Rab7 target protein, Rabring7, which contains a RING finger domain at its C termini, but the precise role of Rabring7 remains unknown. In this study, we demonstrate using an in vitro ub...

    journal_title：Biochemical and biophysical research communications

    pub_type： 杂志文章

    doi：10.1016/j.bbrc.2007.04.052

    authors： Sakane A,Hatakeyama S,Sasaki T

    更新日期：2007-06-15 00:00:00