Differential vulnerability of snake species to MPTP: a behavioral and biochemical comparison in ratsnakes (Elaphe) and watersnakes (Nerodia).

abstract：:Ultrasonic calls are emitted by many species of rodents in a variety of situations. In particular, infants commonly emit such calls when removed from the nest; the rate and intensity of calling are related to the degree of development of homoiothermy. The relevant biological significance of these signals is documented...

journal_title：Neurotoxicology and teratology

authors： Cuomo V,De Salvia MA,Maselli MA,Santo L,Cagiano R

更新日期：1987-03-01 00:00:00

abstract：:The potential of emamectin benzoate (EB) to cause developmental neurotoxicity in Sprague-Dawley rats was assessed using a study design by the US EPA. Dosages of 0 (deionized water), 0.1, 0.6, or 3.6 mg/kg/day were administered at 5 ml/kg by oral gavage from gestational day (GD) 6 to lactational day (LD) 20 to groups o...

journal_title：Neurotoxicology and teratology

authors： Wise LD,Allen HL,Hoe CM,Verbeke DR,Gerson RJ

更新日期：1997-07-01 00:00:00

abstract：:In the United States, the regulation and testing of chemicals that may impact on human health is mandated by a number of different laws and regulated by several government agencies. Toxicologic screening in laboratory animals has created a major database for predicting adverse health effects of drugs, food and cosmeti...

journal_title：Neurotoxicology and teratology

authors： Steinberg M

更新日期：1987-11-01 00:00:00

abstract：:Zebrafish provide a powerful model of the impacts of embryonic toxicant exposure on neural development that may result in long-term behavioral dysfunction. In this study, zebrafish embryos were treated with 1.5mM strychnine for short embryonic time windows to induce transient changes in inhibitory neural signaling, an...

journal_title：Neurotoxicology and teratology

authors： Roy NM,Arpie B,Lugo J,Linney E,Levin ED,Cerutti D

更新日期：2012-11-01 00:00:00

abstract：:Monensin, a growth-promoting agent and coccidiostat used in veterinary medicine, was studied in terms of its effects on the development of female rats and their offspring when added to the diet. Young female rats received 100 or 300 ppm monensin mixed with powdered chow diet until adulthood, when they were mated and t...

journal_title：Neurotoxicology and teratology

authors： de Souza Spinosa H,Nicolau A,Maruo VM,Bernardi MM

更新日期：1999-07-01 00:00:00

abstract：:Preclinical studies suggest that propofol may cause damage to immature neurons. However, the effect of maternal propofol exposure on the neuronal development of the offspring is largely unknown. In this study, pregnant rats were assigned to receive continuous infusion of saline (control) or propofol for 1 h (1HP) or 2...

journal_title：Neurotoxicology and teratology

authors： Li J,Xiong M,Alhashem HM,Zhang Y,Tilak V,Patel A,Siegel A,Ye JH,Bekker A

更新日期：2014-05-01 00:00:00

abstract：:Animals exposed prenatally to alcohol (4 g/kg/day) via maternal peroral intubation or control offspring were reared after weaning either alone in standard steel/wire cages or in groups of eight, for 6 weeks. Rats exposed prenatally to alcohol and reared in isolation had a dysmetric stride length indicative of an ataxi...

journal_title：Neurotoxicology and teratology

authors： Hannigan JH,Berman RF,Zajac CS

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:We have previously reported the inverse associations between in utero levels of lead (Pb), arsenic (As) (i.e., toxic elements), and neurodevelopmental indicators (i.e., motor and state regulation cluster score) measured by the Brazelton Neonatal Behavioral Assessment Scale, third edition (NBAS III) in this c...

journal_title：Neurotoxicology and teratology

authors： Parajuli RP,Fujiwara T,Umezaki M,Furusawa H,Watanabe C

更新日期：2014-01-01 00:00:00

abstract：:Sulfites, which are commonly used as preservatives, are continuously formed in the body during metabolism of sulfur-containing amino acids. Sulfite is oxidized to sulfate ion by sulfite oxidase (SOX, EC. 1.8.3.1). The aim of this study was to investigate the possible toxic effects of sulfite on neurons by measuring ac...

journal_title：Neurotoxicology and teratology

authors： Küçükatay V,Savcioğlu F,Hacioğlu G,Yargiçoğlu P,Ağar A

更新日期：2005-01-01 00:00:00

abstract：:The study aim was to determine whether low level exposure to organophosphate pesticides (OPs) causes neuropsychological or psychiatric impairment. Methodological weaknesses of earlier studies were addressed by: recruiting participants who had retired on ill health grounds; excluding participants with a history of acut...

journal_title：Neurotoxicology and teratology

authors： Mackenzie Ross SJ,Brewin CR,Curran HV,Furlong CE,Abraham-Smith KM,Harrison V

更新日期：2010-07-01 00:00:00

abstract：:The present study was designed to investigate the possible involvement of TLR4 pathway in the mouse hippocampus following toluene exposure. Male C3H/HeN and C3H/HeJ (TLR4 defective) mice were exposed to 0, 5, 50 or 500 ppm of toluene for 6 weeks. The expressions of TLR4-related signal transduction pathway mRNAs in the...

journal_title：Neurotoxicology and teratology

authors： Win-Shwe TT,Kunugita N,Yoshida Y,Fujimaki H

更新日期：2011-09-01 00:00:00

abstract：:The increased use of cocaine in the United States and worldwide has created great concern about its effects on fetuses and neonates of pregnant cocaine abusers. The effects on neonates are varied: fetal growth delay, microcephaly, abnormal neurological functions, microphthalmia, and maternal obstetric complications. I...

journal_title：Neurotoxicology and teratology

authors： Méndez-Armenta M,Barroso-Moguel R,Villeda-Hernández J,Romero-Díaz V,Ríos C

更新日期：1997-05-01 00:00:00

abstract：:Toluene can be considered an ototoxic chemical compound in the rat. Outer hair cells are particularly sensitive to this aromatic organic solvent or to one of its metabolites. The objective of the present study was to evaluate the possible role played by cysteine S-conjugates in the ototoxic process in Long-Evans rats....

journal_title：Neurotoxicology and teratology

authors： Waniusiow D,Campo P,Cossec B,Cosnier F,Grossman S,Ferrari L

更新日期：2008-05-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Neurotoxicology and teratology

authors： Cross NC,Chelonis JJ,Finch MN,Edwards MC,Baldwin RL

更新日期：2009-02-05 00:00:00

abstract：:Numerous experiments have shown that the aromatic solvents can affect the auditory system in the rat, the cochlea being targeted first. Solvents differ in cochleotoxic potency: for example, styrene is more ototoxic than toluene or xylenes. The goal of this study was to determine the relative ototoxicity of the three i...

journal_title：Neurotoxicology and teratology

authors： Maguin K,Lataye R,Campo P,Cossec B,Burgart M,Waniusiow D

更新日期：2006-11-01 00:00:00

abstract：:Rats were fed a liquid diet containing ethanol from days 6-19 of gestation. Controls were pair-fed the same diet with sucrose substituted for ethanol, or received ad lib chow and water. The activity of the offspring was observed at 10, 16, 22 or 28 days-of-age. Overall, offspring exposed to alcohol prenatally were hyp...

journal_title：Neurotoxicology and teratology

authors： Bond NW

更新日期：1988-01-01 00:00:00

abstract：:Pregnant Sprague-Dawley rats were fed a liquid diet containing either 0% (group C), 18% (group L), or 36% (group H) ethanol-derived calories (EDC) from gestational day 1 to 20. Male offspring were assessed under a conditioned taste aversion paradigm (PND 35-45), in a complex maze (PND 68-80), and for operant behavior ...

journal_title：Neurotoxicology and teratology

authors： Clausing P,Ferguson SA,Holson RR,Allen RR,Paule MG

更新日期：1995-09-01 00:00:00

abstract：:The discovery of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) leads to the hypothesis that Parkinson's disease (PD) is maybe initiated or precipitated by environmental or endogenous toxins by the mechanism similar to that of MPTP in genetically-predisposed individuals. Endogenous analogs of MPTP, such as beta-c...

journal_title：Neurotoxicology and teratology

authors： Matsubara K,Aoyama K,Suno M,Awaya T

更新日期：2002-09-01 00:00:00

abstract：:Perfluorinated alkyls are widely-used agents that accumulate in ecosystems and organisms because of their slow rate of degradation. There is increasing concern that these agents may be developmental neurotoxicants and the present study was designed to develop an avian model for the neurobehavioral teratogenicity of pe...

journal_title：Neurotoxicology and teratology

authors： Pinkas A,Slotkin TA,Brick-Turin Y,Van der Zee EA,Yanai J

更新日期：2010-03-01 00:00:00

abstract：:Consumption of the nutrients omega-3 fatty acids (omega-3 FA) during pregnancy and lactation is considered beneficial to fetal and infant development. It may also reduce the incidence and severity of preterm births by prolonging gestational length. However several recent human and animal studies have reported that ove...

journal_title：Neurotoxicology and teratology

authors： Church MW,Jen KL,Stafferton T,Hotra JW,Adams BR

更新日期：2007-03-01 00:00:00

abstract：:High exposure to toluene may cause optic neuropathy and retinopathy, both associated with dyschromatopsia. Another solvent, ethanol, is known to induce acute blue-yellow dyschromatopsia. This study investigated the acute effects of high doses of toluene on color vision. Eight male printshop workers were examined befor...

journal_title：Neurotoxicology and teratology

authors： Muttray A,Wolters V,Jung D,Konietzko J

更新日期：1999-01-01 00:00:00

abstract：:The present study was designed to investigate the in vivo effects of monosodium glutamate (MSG) and aspartame (ASM) individually and in combination on the cognitive behavior and biochemical parameters like neurotransmitters and oxidative stress indices in the brain tissue of mice. Forty male Swiss albino mice were ran...

journal_title：Neurotoxicology and teratology

authors： Abu-Taweel GM,A ZM,Ajarem JS,Ahmad M

更新日期：2014-03-01 00:00:00

abstract：:Most epileptic women delivering children each year take anticonvulsants throughout pregnancy. The teratogenic potential of anticonvulsants is most notable for phenytoin, trimethadione, valproic acid, and carbamazepine. This review focuses on the human and animal evidence for the teratogenicity of phenytoin, with empha...

journal_title：Neurotoxicology and teratology

authors： Adams J,Vorhees CV,Middaugh LD

更新日期：1990-05-01 00:00:00

abstract：:While the toxic effects of lead have been recognized for millennia, it has remained a significant public health concern due to its continued use and toxicological potential. Of particular interest is the increased susceptibility of young children to the toxic effects of lead. Although the exact mechanism(s) for lead t...

journal_title：Neurotoxicology and teratology

authors： Dribben WH,Creeley CE,Farber N

更新日期：2011-07-01 00:00:00

abstract：:The central and peripheral nervous system effects of acute and subchronic exposure to three organic phosphoro-acid esters (dimethoate, dichlorvos, parathion-methyl) were studied. CNS-dependent variables included mean EEG amplitude, mean frequency of the EEG, and the activity (power density) of six component frequency ...

journal_title：Neurotoxicology and teratology

authors： Nagymajtényi L,Dési I,Lorencz R

更新日期：1988-09-01 00:00:00

abstract：:Memory problems lasting 8 months have previously been described for a small group of female solvent workers following an accidental workplace solvent intoxication. Three years after the intoxication the presence of longer-term residual impairment of cognitive functions was evaluated. The major residual difficulty unco...

journal_title：Neurotoxicology and teratology

authors： Stollery BT

更新日期：1996-07-01 00:00:00

abstract：:The effects of a 14-day (gestation days 7-20) chronic methadone (6.3-9.0 mg/kg/day) infusion via osmotic minipumps were studied on the induction of physical dependence in both pregnant and nonpregnant female rats. Following continued methadone exposure, an acute injection of naloxone (2.0 mg/kg, SC) produced the follo...

journal_title：Neurotoxicology and teratology

authors： Darmani NA,Saady JJ,Schnoll SH,Martin BR

更新日期：1991-11-01 00:00:00

abstract：:Bromantan (N-[2-adamantil]-N-[para-bromphenyl]amine) is an "actoprotective" drug widely used in Russia as a muscle performance-enhancing agent for sportsmen and as an immunostimulator in medicine. Experiments were conducted to determine whether this compound has adverse effects on the reproduction and development of o...

journal_title：Neurotoxicology and teratology

authors： Iezhitsa IN,Spasov AA,Bugaeva LI

更新日期：2001-03-01 00:00:00

abstract：:The identification of mechanisms and outcomes for neurobehavioral teratogenesis is critical to our ability to develop therapies to ameliorate or reverse the deleterious effects of exposure to developmental neurotoxicants. We established mechanistically-based complementary models for the study of cholinergic systems in...

journal_title：Neurotoxicology and teratology

authors： Yanai J,Brick-Turin Y,Dotan S,Langford R,Pinkas A,Slotkin TA

更新日期：2010-01-01 00:00:00

abstract：:The effect of subdiaphragmatic vagotomy on the acquisition of a radiation-induced taste aversion was examined to assess the importance of the vagus nerve in transmitting information on the peripheral toxicity of radiation to the brain. Vagotomy had no effect on taste aversion learning, consistent with reports using ot...

journal_title：Neurotoxicology and teratology

authors： Hunt WA,Rabin BM,Lee J

更新日期：1987-01-01 00:00:00