Evidence that behavioral depression does not influence airway cell influx in allergic rats.

Abstract:

:This study was designated to evaluate the influence of behavioral depression on the airway leukocyte recruitment in allergic animals. To achieve this, total and differential cell counts in bronchoalveolar (BAL) fluid of ovalbumin (OVA)-sensitized and depressed rats was evaluated. Inescapable electric footshock, applied on day 0, 7 and 13 after OVA sensitization, was used as a model to induce depression. In both nondepressed and depressed groups, the number of total and differential cells (eosinophils and mononuclear cells) in BAL fluid was significantly larger in sensitized compared with non-sensitized animals. However, no statistical differences were found between these groups with respect to the number of total and differential leukocytes, irrespective of the day inescapable shock was applied. Thus, behavioral depression does not influence the pattern of cell infiltration into the airways of allergen-induced airway inflammation.

journal_name

Mediators Inflamm

authors

Varriano MA,Varriano AA,Datti F,Datti M,Antunes E,Teixeira NA

doi

10.1080/09629350124118

subject

Has Abstract

pub_date

2001-08-01 00:00:00

pages

229-32

issue

4

eissn

0962-9351

issn

1466-1861

journal_volume

10

pub_type

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