The evolution of inflammatory mediators.

abstract：:Macrophage migration inhibitory factor (MIF) has recently been forwarded as a critical regulator of inflammatory conditions, and it has been hypothesized that MIF may have a role in the pathogenesis of asthma and chronic obstructive pulmonary disease (COPD). Hence, we examined effects of MIF immunoneutralization on th...

journal_title：Mediators of inflammation

authors： Korsgren M,Källström L,Uller L,Bjerke T,Sundler F,Persson CG,Korsgren O

更新日期：2000-01-01 00:00:00

abstract：Aims:To assess the maresin 1 (MaR1) contents in type 2 diabetic patients with or without diabetic foot ulcer and to analyze the association of MaR1 concentrations with several metabolism-related parameters. Methods:Plasma MaR1 concentrations were analyzed in 96 subjects with normal glucose tolerant (NC, n = 43), type ...

journal_title：Mediators of inflammation

authors： Miao T,Huang B,He N,Sun L,Du G,Gong X,Xu Y,Zheng Y,Zheng H,Qu H

更新日期：2020-04-16 00:00:00

abstract：:The observed effects after ozone exposure strongly depend on ozone concentration and exposure time. We hypothesized that depending on the O3 exposure protocol, mainly either an oxidant damage or an inflammation will determine the O3 toxicity. We compared two different ozone exposure protocols: an acute exposure (3 ppm...

journal_title：Mediators of inflammation

authors： van Hoof HJ,Zijlstra FJ,Voss HP,Garrelds IM,Dormans JA,van Bree L,Bast A

更新日期：1997-01-01 00:00:00

abstract：:Macrophages play a special role in the onset of several diseases, including acute and chronic kidney injuries. In this sense, tubule interstitial nephritis (TIN) represents an underestimated insult, which can be triggered by different stimuli and, in the absence of a proper regulation, can lead to fibrosis deposition....

journal_title：Mediators of inflammation

authors： Correa-Costa M,Braga TT,Felizardo RJ,Andrade-Oliveira V,Perez KR,Cuccovia IM,Hiyane MI,da Silva JS,Câmara NO

更新日期：2014-01-01 00:00:00

abstract：:Early onset sepsis due to group B streptococcus leads to neonatal morbidity, increased mortality, and long-term neurological deficencies. Interaction between septicemic GBS and confluent monolayers of human coronary artery endothelial cells (HCAECs) was analyzed by genome wide expression profiling. In total, 124 genes...

journal_title：Mediators of inflammation

authors： Beyrich C,Löffler J,Kobsar A,Speer CP,Kneitz S,Eigenthaler M

更新日期：2011-01-01 00:00:00

abstract：:Human respiratory syncytial virus (RSV) sometimes causes acute and severe lower respiratory tract illness in infants and young children. RSV strongly upregulates proinflammatory cytokines and the platelet-activating factor (PAF) receptor, which is a receptor for Streptococcus pneumoniae, in the pulmonary epithelial ce...

journal_title：Mediators of inflammation

authors： Yokota S,Okabayashi T,Hirakawa S,Tsutsumi H,Himi T,Fujii N

更新日期：2012-01-01 00:00:00

abstract：:Acute lung injury (ALI) is characterized by alveolar edema and uncontrolled neutrophil migration to the lung, and no specific therapy is still available. Ellagic acid, a compound present in several fruits and medicinal plants, has shown anti-inflammatory activity in several experimental disease models. We used the non...

journal_title：Mediators of inflammation

authors： Cornélio Favarin D,Martins Teixeira M,Lemos de Andrade E,de Freitas Alves C,Lazo Chica JE,Artério Sorgi C,Faccioli LH,Paula Rogerio A

更新日期：2013-01-01 00:00:00

abstract：:It is hypothesized that central nervous system inflammation induced by systematic inflammation due to surgical trauma plays a critical role in postoperative cognitive dysfunction. The potential inhibitory effect of nerve blockage with local anesthetics on peripheral inflammatory response has been reported. We hypothes...

journal_title：Mediators of inflammation

authors： He Y,Li Z,Zuo YX

更新日期：2015-01-01 00:00:00

abstract：:The stalks of Polygonum hydropiper L. (PHL) have been traditionally used in clinical practice for thousands of years in China to treat various inflammatory diseases. However, little research has been conducted to investigate the anti-inflammatory effects of PHL on TNBS-induced intestinal inflammation in rats. The aim ...

journal_title：Mediators of inflammation

authors： Zhang W,Pan Y,Qu S,Wang D,Cheng S,Liu X

更新日期：2018-05-07 00:00:00

abstract：:Severe acute pancreatitis (SAP) characterized by atrocious progression and numerous complications often leads to a high mortality rate due to hypermetabolism, systemic inflammatory response syndrome (SIRS), and multiple organs dysfunction syndrome (MODS). Studies have revealed that both early enteral nutrition (EEN) a...

journal_title：Mediators of inflammation

authors： Wang G,Sun B,Gao Y,Meng QH,Jiang HC

更新日期：2007-01-01 00:00:00

abstract：:Amyotrophic lateral sclerosis (ALS) is considered a multifactorial, multisystem disease in which inflammation and the immune system play important roles in development and progression. The pleiotropic cytokine TNFα is one of the major players governing the inflammation in the central nervous system and peripheral dist...

journal_title：Mediators of inflammation

authors： Tortarolo M,Lo Coco D,Veglianese P,Vallarola A,Giordana MT,Marcon G,Beghi E,Poloni M,Strong MJ,Iyer AM,Aronica E,Bendotti C

更新日期：2017-01-01 00:00:00

abstract：:Obesity is marked by chronic, low-grade inflammation. Here, we examined whether intrinsic differences between white and brown adipocytes influence the inflammatory status of macrophages. White and brown adipocytes were characterized by transcriptional regulation of UCP-1, PGC1α, PGC1β, and CIDEA and their level of IL-...

journal_title：Mediators of inflammation

authors： Dowal L,Parameswaran P,Phat S,Akella S,Majumdar ID,Ranjan J,Shah C,Mogre S,Guntur K,Thapa K,Gesta S,Vishnudas VK,Narain NR,Sarangarajan R

更新日期：2017-01-01 00:00:00

abstract：:Although the initiating events of Crohn's disease are unknown, models of experimental colitis have provided new insights in the immunologically mediated pathways of mucosal inflammation. In Crohn's disease activated mucosal T lymphocytes produce proinflammatory cytokines within the mucosal compartment. With this under...

journal_title：Mediators of inflammation

authors： van Montfrans C,Camoglio L,van Deventer SJ

更新日期：1998-01-01 00:00:00

abstract：:Psoriasis is a common chronic inflammatory multisystemic disease with a complex pathogenesis consisting of genetic, immunological, and environmental components. It is associated with a number of comorbidities, including diabetes, metabolic syndrome, obesity, and myocardial infarction. In addition, the severity of psor...

journal_title：Mediators of inflammation

authors： Rodríguez-Cerdeira C,Cordeiro-Rodríguez M,Carnero-Gregorio M,López-Barcenas A,Martínez-Herrera E,Fabbrocini G,Sinani A,Arenas-Guzmán R,González-Cespón JL

更新日期：2019-05-28 00:00:00

abstract：:Non-cystic fibrosis-related bronchiectasis is a chronic inflammatory lung disease, which is regarded as an "orphan" lung disease, with little research devoted to the study of this condition. Bronchiectasis results in impaired quality of life and mortality if left untreated. The tools available in the armamentarium for...

journal_title：Mediators of inflammation

authors： Masekela R,Green RJ

更新日期：2012-01-01 00:00:00

abstract：:Chronic kidney disease (CKD) patients, characterized by traditional and nontraditional risk factors, are prone to develop atheromatosis and thus cardiovascular events and mortality. The angiogenesis of the adventitial vasa vasorum (aVV) surrounding the carotid has been described as the atheromatosis initiator. Therefo...

journal_title：Mediators of inflammation

authors： Arcidiacono MV,Martinez-Alonso M,Belart M,Vilar A,Martín M,Craver L,Betriu À,Mauricio D,Valdivielso JM,Fernández E,Borràs M

更新日期：2017-01-01 00:00:00

abstract：:The objective of this study was to evaluate the effects of peptides derived from synbiotics on improving inflammatory bowel disease (IBD). Five-week-old male C57BL/6 mice were administered with dextran sulfate sodium (DSS) via drinking water for seven days to induce IBD (IBD group). The mice in the IBD group were oral...

journal_title：Mediators of inflammation

authors： Ha J,Oh H,Oh NS,Seo Y,Kang J,Park MH,Kim KS,Kang SH,Yoon Y

更新日期：2020-07-04 00:00:00

abstract：:Daily food intake is crucial to maintain health and determine endogenous fuel to practice endurance exercise. We investigated the association between quantity of macronutrient and micronutrient daily intake and inflammation induced by long-distance exercise. Methods. Forty-four Brazilian male amateurs' marathon finish...

journal_title：Mediators of inflammation

authors： Passos BN,Lima MC,Sierra APR,Oliveira RA,Maciel JFS,Manoel R,Rogante JI,Pesquero JB,Cury-Boaventura MF

更新日期：2019-10-07 00:00:00

abstract：BACKGROUND:This study aims to investigate the effect of feeding low-fat diet (LFD) to diet-induced obesity (DIO) mice lacking TLR5 (TLR5(-/-)), which have a tendency to develop glucose intolerance with increased adiposity, compared to that in C57BL/6 mice. RESULTS:TLR5(-/-) and C57BL/6 male mice were divided into thre...

journal_title：Mediators of inflammation

authors： Wu SC,Rau CS,Lu TH,Tzeng SL,Wu YC,Wu CJ,Lin CW,Hsieh CH

更新日期：2015-01-01 00:00:00

abstract：:Cardiovascular (CV) disease is the most common cause of premature mortality in patients with rheumatoid arthritis (RA). It is the result of an accelerated atherosclerotic process. Both RA and atherosclerosis are complex polygenic diseases. Besides traditional CV risk factors and chronic inflammation, a number of studi...

journal_title：Mediators of inflammation

authors： Rodríguez-Rodríguez L,López-Mejías R,García-Bermúdez M,González-Juanatey C,González-Gay MA,Martín J

更新日期：2012-01-01 00:00:00

abstract：:Galectin-1 (Gal-1), an evolutionarily conserved β-galactoside-binding lectin, controls immune cell homeostasis and tempers acute and chronic inflammation by blunting proinflammatory cytokine synthesis, engaging T-cell apoptotic programs, promoting expansion of T regulatory (Treg) cells, and deactivating antigen-presen...

journal_title：Mediators of inflammation

authors： Seropian IM,González GE,Maller SM,Berrocal DH,Abbate A,Rabinovich GA

更新日期：2018-11-05 00:00:00

abstract：UNLABELLED:The aim of this study was to investigate the relationship between urinary eosinophil protein X (uEPX) and asthma symptoms, lung function, and other markers of eosinophilic airway inflammation in asthmatic school children. METHODS:A cross-sectional study was performed in 180 steroid dependent atopic children...

journal_title：Mediators of inflammation

authors： Nuijsink M,Hop WC,Sterk PJ,Duiverman EJ,Hiemstra PS,de Jongste JC,CATO Study Group.

更新日期：2007-01-01 00:00:00

abstract：:To elucidate the modulatory role of histamine-degrading enzymes in airway constrictor responses, human bronchial strips were studied under isometric conditions in vitro. Pretreatment of tissues with the histamine N-methyltransferase (HMT) inhibitor SKF 91488 specifically potentiated the contractile responses to histam...

journal_title：Mediators of inflammation

authors： Tamaoki J,Chiyotani A,Tagaya E,Isono K,Konno K

更新日期：1994-01-01 00:00:00

abstract：:Autism is a neurodevelopmental disorder characterized by problems in communication, social skills, and repetitive behavior. Recent studies suggest that apoptotic and inflammatory mechanisms may contribute to the pathogenesis of this disorder. Nuclear factor-κB (NF-κB) is an important gene transcriptional factor involv...

journal_title：Mediators of inflammation

authors： Malik M,Tauqeer Z,Sheikh AM,Wen G,Nagori A,Yang K,Brown WT,Li X

更新日期：2011-01-01 00:00:00

abstract：:Rheumatoid arthritis (RA), a chronic inflammatory disease usually occurring in synovial tissues and joints, is highly associated with genetic and environmental factors. ORAI1, a gene related to cellular immune system, has been shown to be involved in the pathogenesis of chronic inflammatory diseases and immune disease...

journal_title：Mediators of inflammation

authors： Yen JH,Chang CM,Hsu YW,Lee CH,Wu MS,Hwang DY,Chen BK,Liao HT,Wu MT,Chang WC

更新日期：2014-01-01 00:00:00

abstract：:Inflammatory bowel diseases (IBD) are multifactorial disorders resulting from environmental and genetic factors. Polymorphisms in MDR1 and GSTs genes might explain individual differences in susceptibility to IBD. We carried out a case-control study to examine the association of MDR1 (C1236T and C3435T), GSTT1, and GST...

journal_title：Mediators of inflammation

authors： Senhaji N,Kassogue Y,Fahimi M,Serbati N,Badre W,Nadifi S

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To assess FGF-β, TGF-β, and COX2 expression and immunocompetent cells in the orbital tissue of patients with severe and mild Graves' orbitopathy. PATIENTS AND METHODS:Orbital tissue was taken from 27 patients with GO: (1) severe GO (n = 18), the mean clinical activity score (CAS) being 8.5 (SD 2.5); and (2) mi...

journal_title：Mediators of inflammation

authors： Pawlowski P,Reszec J,Eckstein A,Johnson K,Grzybowski A,Chyczewski L,Mysliwiec J

更新日期：2014-01-01 00:00:00

abstract：:Group A streptococcus (GAS) imposes a great burden on humans. Efforts to minimize the associated morbidity and mortality represent a critical issue. Glycogen synthase kinase-3 β (GSK-3 β) is known to regulate inflammatory response in infectious diseases. However, the regulation of GSK-3 β in GAS infection is still unk...

journal_title：Mediators of inflammation

authors： Chang YT,Chen CL,Lin CF,Lu SL,Cheng MH,Kuo CF,Lin YS

更新日期：2013-01-01 00:00:00

abstract：:Systemic sclerosis (SSc) is an autoimmune connective tissue disorder of unknown etiology. This disease is characterized by a large variety of clinical patterns, which include the fibrosis of skin and visceral organs causing a variety of clinical manifestations. Genetic and environmental factors participate in the etio...

journal_title：Mediators of inflammation

authors： Grygiel-Górniak B,Puszczewicz M

更新日期：2014-01-01 00:00:00

abstract：AIM:This study was undertaken in order to determine whether anti-inflammatory cytokine interleukin-10 is responsible for a previously described protection against Klebsiella infection mediated by antilipopolysaccharide antibodies. METHODS:BALB/c mice were infected intraperitoneally with a lethal challenge of Klebsiell...

journal_title：Mediators of inflammation

authors： Rukavina T,Ticac B,Vasiljev V

更新日期：2006-01-01 00:00:00