Cytokine profile of Ehrlich ascites tumor treated with Bothrops jararaca venom.

abstract：:The therapeutic strategies used in the treatment of hepatitis C are essentially based on the combination of direct-acting antiviral agents (DAAs). This therapy has been shown to be very effective in relation to patient adherence to treatment and has shown high rates of sustained virological response (SVR). However, th...

journal_title：Mediators of inflammation

authors： Pereira GL,Tarragô AM,Neves WLL,da Silva Neto PV,de Souza PS,Dos Santos Affonso J,de Sousa KS,da Silva JA,Costa AG,da Silva Victoria F,Victoria MB,Malheiro A

更新日期：2019-11-04 00:00:00

abstract：:Procalcitonin (PCT) is one of the best diagnostic and prognostic markers in clinical practice, widely used to evaluate the evolution of bacterial infections. Although it is mainly produced by thyroid, during sepsis almost all the peripheral tissues are involved in PCT production. Parenchymal cells have been suggested ...

journal_title：Mediators of inflammation

authors： Rami D,La Bianca M,Agostinis C,Zauli G,Radillo O,Bulla R

更新日期：2014-01-01 00:00:00

abstract：:Obesity is marked by chronic, low-grade inflammation. Here, we examined whether intrinsic differences between white and brown adipocytes influence the inflammatory status of macrophages. White and brown adipocytes were characterized by transcriptional regulation of UCP-1, PGC1α, PGC1β, and CIDEA and their level of IL-...

journal_title：Mediators of inflammation

authors： Dowal L,Parameswaran P,Phat S,Akella S,Majumdar ID,Ranjan J,Shah C,Mogre S,Guntur K,Thapa K,Gesta S,Vishnudas VK,Narain NR,Sarangarajan R

更新日期：2017-01-01 00:00:00

abstract：:Fibroblasts are important to host defence and immunity, can also as initiators of inflammation as well. As the endogenous "braking signal", Lipoxins can regulate anti-inflammation and the resolution of inflammation. We investigated the effect of lipoxinA(4) on the expression of cyclooxygenase-2 in lipopolysaccharide-s...

journal_title：Mediators of inflammation

authors： Zheng S,Wang Q,He Q,Song X,Ye D,Gao F,Jin S,Lian Q

更新日期：2011-01-01 00:00:00

abstract：:Nephrolithiasis is characterized by calcification of stones in the kidneys from an unknown cause. Animal models demonstrated the functional roles of the transient receptor potential vanilloid member 5 (TRPV5) gene in calcium renal reabsorption and hypercalciuria. Therefore, TRPV5 was suggested to be involved in calciu...

journal_title：Mediators of inflammation

authors： Khaleel A,Wu MS,Wong HS,Hsu YW,Chou YH,Chen HY

更新日期：2015-01-01 00:00:00

abstract：:Prevalence of thyroid dysfunction and its impact on cognition in older people has been demonstrated, but many points remain unclarified. In order to study the effect of aging on the thyroid gland, we compared the thyroid gland of very old mice with that of younger ones. We have first investigated the changes of thyroi...

journal_title：Mediators of inflammation

authors： Traina G,Cataldi S,Siccu P,Loreti E,Ferri I,Sidoni A,Codini M,Gizzi C,Sichetti M,Ambesi-Impiombato FS,Beccari T,Curcio F,Albi E

更新日期：2017-01-01 00:00:00

abstract：:Group A streptococcus (GAS) imposes a great burden on humans. Efforts to minimize the associated morbidity and mortality represent a critical issue. Glycogen synthase kinase-3 β (GSK-3 β) is known to regulate inflammatory response in infectious diseases. However, the regulation of GSK-3 β in GAS infection is still unk...

journal_title：Mediators of inflammation

authors： Chang YT,Chen CL,Lin CF,Lu SL,Cheng MH,Kuo CF,Lin YS

更新日期：2013-01-01 00:00:00

abstract：:The success of peritoneal dialysis (PD) is dependent on the structural and functional integrity of the peritoneal membrane. The mesothelium lines the peritoneal membrane and is the first line of defense against chemical and/or bacterial insult. Peritonitis remains a major complication of PD and is a predominant cause ...

journal_title：Mediators of inflammation

authors： Yung S,Chan TM

更新日期：2012-01-01 00:00:00

abstract：:Periploca forrestii Schltr. has been used as a Chinese folk medicine due to its versatile pharmacological effects such as promoting wounds and rheumatoid arthritis. However, the antiarthritic activity of Periploca forrestii saponin (PFS) and its active compound Periplocin has still not been demonstrated. Here, we eval...

journal_title：Mediators of inflammation

authors： Liu Y,Li M,He Q,Yang X,Ruan F,Sun G

更新日期：2016-01-01 00:00:00

abstract：:The metabolic syndrome is a cluster of cardiometabolic alterations that include the presence of arterial hypertension, insulin resistance, dyslipidemia, and abdominal obesity. Obesity is associated with a chronic inflammatory response, characterized by abnormal adipokine production, and the activation of proinflammato...

journal_title：Mediators of inflammation

authors： Fuentes E,Fuentes F,Vilahur G,Badimon L,Palomo I

更新日期：2013-01-01 00:00:00

abstract：:In this study we demonstrated that ΔCaecm33 double mutant showed reduced biofilm formation and causes less damage to gingival mucosa tissues. This was confirmed by the reduced level of necrotic cells and Bax/Bcl2 gene expression as apoptotic markers. In contrast, parental and Caecm33 mutant strains decreased basement ...

journal_title：Mediators of inflammation

authors： Rouabhia M,Semlali A,Chandra J,Mukherjee P,Chmielewski W,Ghannoum MA

更新日期：2012-01-01 00:00:00

abstract：:Matrix metalloproteinase 9 is a proteolytic enzyme which is recently one of the more often studied biomarkers. Its possible use as a biomarker of neuronal damage in stroke, heart diseases, tumors, multiple sclerosis, and epilepsy is being widely indicated. In epilepsy, MMP-9 is suggested to play a role in epileptic fo...

journal_title：Mediators of inflammation

authors： Bronisz E,Kurkowska-Jastrzębska I

更新日期：2016-01-01 00:00:00

abstract：:It has been suggested that the supernatant of LPSstimulated macrophages (macrophage nociceptive factor, MNF) promotes nociception in mice. Intraperitoneal administration of MNF induced dose-related writhing, which reached a plateau between 18 and 26 min after injection and decreased within 60 min. The release of MNF w...

journal_title：Mediators of inflammation

authors： Thomazzi SM,Ribeiro RA,Campos DI,Cunha FQ,Ferreira SH

更新日期：1997-01-01 00:00:00

abstract：:The expression of cytochrome P4501A1 (CYP1A1) enzyme is changed in various organs during the host response to inflammation or infection, leading to alterations in the metabolism of endogenous and exogenous compounds. Results of this study showed that CYP1A1 expression was significantly downregulated in the mammary tis...

journal_title：Mediators of inflammation

authors： Zhang WY,Wang H,Qi S,Wang X,Li X,Zhou K,Zhang Y,Gao MQ

更新日期：2018-02-28 00:00:00

abstract：:Multiple sclerosis is an autoimmune disease with classical traits of demyelination, axonal damage, and neurodegeneration. The migration of autoimmune T cells and macrophages from blood to central nervous system as well as the destruction of blood brain barrier are thought to be the major processes in the development o...

journal_title：Mediators of inflammation

authors： Cheng W,Chen G

更新日期：2014-01-01 00:00:00

abstract：:Background. Growth arrest-specific (Gas) 6 is one of the endogenous ligands of TAM receptors (Tyro3, Axl, and Mertk), and its role as an immune modulator has been recently emphasized. Naturally occurring CD4+CD25+ regulatory T cells (Tregs) are essential for the active suppression of autoimmunity. The present study wa...

journal_title：Mediators of inflammation

authors： Zhao GJ,Zheng JY,Bian JL,Chen LW,Dong N,Yu Y,Hong GL,Chandoo A,Yao YM,Lu ZQ

更新日期：2017-01-01 00:00:00

abstract：:Chemokines (CKs) and chemokine receptors (CKR) promote leukocyte recruitment into cardiac tissue infected by the Trypanosoma cruzi. This study investigated the long-term treatment with subantimicrobial doses of doxycycline (Dox) in association, or not, with benznidazole (Bz) on the expression of CK and CKR in cardiac ...

journal_title：Mediators of inflammation

authors： de Paula Costa G,Lopes LR,da Silva MC,Horta AL,Pontes WM,Milanezi CM,Guedes PM,de Lima WG,Schulz R,da Silva JS,Talvani A

更新日期：2016-01-01 00:00:00

abstract：:Acute kidney injury (AKI), a clinical syndrome, is a sudden onset of kidney failure that severely affects the kidney tubules. One potential treatment is dexmedetomidine (DEX), a highly selective α2-adrenoreceptor agonist that is used as an anesthetic adjuvant. It also has anti-inflammatory, neuroprotective, and sympat...

journal_title：Mediators of inflammation

authors： Bao N,Dai D

更新日期：2020-04-03 00:00:00

abstract：:The causes of retinal hypoxia are many and varied. Under hypoxic conditions, a variety of soluble factors are secreted into the vitreous cavity including growth factors, cytokines, and chemokines. Cytokines, which usually serve as signals between neighboring cells, are involved in essentially every important biologica...

journal_title：Mediators of inflammation

authors： dell'Omo R,Semeraro F,Bamonte G,Cifariello F,Romano MR,Costagliola C

更新日期：2013-01-01 00:00:00

abstract：:The role of eosinophils in inflammation and their mode of activation is not well understood. Eosinophil accumulation and subsequent expression of cytokines at the site of inflammation may play a role in exacerbation of inflammatory responses. In the present study, we have examined the role of TNF-alpha in eosinophil a...

journal_title：Mediators of inflammation

authors： Goldstein LA,Strieter RM,Evanoff HL,Kunkel SL,Lukacs NW

更新日期：1996-01-01 00:00:00

abstract：:Chlamydophila pneumoniae (CPn) is a common respiratory pathogen that causes a chronic and persistent airway infection. The elderly display an increased susceptibility and severity to this infection. However, the underlying mechanisms are not well understood. Dendritic cells (DCs) are the initiators and regulators of i...

journal_title：Mediators of inflammation

authors： Prakash S,Agrawal S,Ma D,Gupta S,Peterson EM,Agrawal A

更新日期：2014-01-01 00:00:00

abstract：:Psoriasis is a common chronic inflammatory multisystemic disease with a complex pathogenesis consisting of genetic, immunological, and environmental components. It is associated with a number of comorbidities, including diabetes, metabolic syndrome, obesity, and myocardial infarction. In addition, the severity of psor...

journal_title：Mediators of inflammation

authors： Rodríguez-Cerdeira C,Cordeiro-Rodríguez M,Carnero-Gregorio M,López-Barcenas A,Martínez-Herrera E,Fabbrocini G,Sinani A,Arenas-Guzmán R,González-Cespón JL

更新日期：2019-05-28 00:00:00

abstract：:Concentrations of acute phase proteins (CRP: C-reactive protein, albumin) change during surgery. We investigated the acute phase response to circumcision and the effects of anaesthesia on this response. The children were divided into four groups; group 1 (intratracheal general anaesthesia, n=40), group 2 (general anae...

journal_title：Mediators of inflammation

authors： Buyukkocak U,Caglayan F,Caglayan O,Basar M,Cakmak M,Batislam E,Ulusoy S

更新日期：2005-10-24 00:00:00

abstract：:As a noninvasive method, exhaled breath condensate (EBC) has gained importance to improve monitoring of lung diseases and to detect biomarkers. The aim of the study was to investigate, whether erythropoietin (EPO) is detectable in EBC. EBC was collected from 22 consecutive patients as well as from healthy individuals....

journal_title：Mediators of inflammation

authors： Schumann C,Triantafilou K,Krueger S,Hombach V,Triantafilou M,Becher G,Lepper PM

更新日期：2006-01-01 00:00:00

abstract：:Little work is done to develop Aloe vera (AV) using probiotics. To explore the potential benefits, the antioxidant effects and the antibacterial effects on foodborne pathogens of Aloe fermentation supernatant were evaluated in vitro. Our results indicated that the Aloe fermentation supernatant fermented by Lactobacill...

journal_title：Mediators of inflammation

authors： Jiang M,Deng K,Jiang C,Fu M,Guo C,Wang X,Wang X,Meng F,Yang S,Deng K,Chen T,Xin H

更新日期：2016-01-01 00:00:00

abstract：INTRODUCTION:Proliferative vitreoretinopathy (PVR) is a severe inflammatory complication of retinal detachment. Pathological epiretinal membranes grow on the retina surface leading to contraction, and surgery fails in 5% to 10% of the cases. We evaluated the expression of VEGF-A, Otx1, Otx2, Otx3, and p53 family member...

journal_title：Mediators of inflammation

authors： Azzolini C,Pagani IS,Pirrone C,Borroni D,Donati S,Al Oum M,Pigni D,Chiaravalli AM,Vinciguerra R,Simonelli F,Porta G

更新日期：2013-01-01 00:00:00

abstract：:In recent years, many researchers are focusing their attention on the link between inflammation and cancer. The inflammation is involved in the tumor development and suppression, by stimulating the immune response. In particular, the transition from chronic inflammation to cancer produces angiogenic and growth factors...

journal_title：Mediators of inflammation

authors： Capone F,Guerriero E,Sorice A,Colonna G,Ciliberto G,Costantini S

更新日期：2016-01-01 00:00:00

abstract：:Little is known about the cause and pathophysiology of middermal elastolysis (MDE). In this condition, variable inflammatory infiltrate may be present or not together with loss of elastic fibres in the middermis that spares both papillary and lower reticular dermis. MDE may be a consequence of abnormal extracellular m...

journal_title：Mediators of inflammation

authors： De Cunto G,Lamberti A,de Santi MM,Miracco C,Fimiani M,Lungarella G,Cavarra E

更新日期：2017-01-01 00:00:00

abstract：:Current studies have identified the multifaceted protective functions of dexmedetomidine on multiple organs. For the first time, we clarify effects of dexmedetomidine on monocyte-endothelial adherence and whether its underlying mechanism is relative to connexin43 (Cx43), a key factor regulating monocyte-endothelial ad...

journal_title：Mediators of inflammation

authors： Chai Y,Yu R,Liu Y,Wang S,Yuan D,Chen J

更新日期：2020-02-10 00:00:00

abstract：OBJECTIVE:To investigate the effects and mechanisms of hydroxytyrosol (HT) during the pathogenesis of myocardial ischemia reperfusion (I/R) in rat hearts. METHODS:The rats were randomized into five groups: sham group, I/R group, HT+I/R group, HT+LY294002+I/R group, and LY+I/R group. Myocardial infarct size, markers of...

journal_title：Mediators of inflammation

authors： Pei YH,Chen J,Xie L,Cai XM,Yang RH,Wang X,Gong JB

更新日期：2016-01-01 00:00:00