Abstract:
:Vascular complications of diabetes mellitus represent a major public health problem. Although many steps forward have been made to define the causes and to find the best possible therapies, the problem remains crucial. In recent years, more and more evidences have defined a link between microbiota and the initiation, promotion, and evolution of atherosclerotic disease, even in the diabetic scenario. There is an urgency to develop the knowledge of modern medicine about the link between gut microbiota and its host's metabolic pathways, and it would be useful to understand and justify the interindividual diversity of clinical disease presentation of diabetic vascular complication even if an optimization of pharmacological treatment has been made or in the case of young patients where hypertension, dyslipidemia, and diabetes are not able to justify a very quick progress of atherosclerotic process. The aim of the present review is to gather all the best available evidence in this regard and to define a new role of the microbiota in this field, from biomarker to possible therapeutic target.
journal_name
Mediators Inflammjournal_title
Mediators of inflammationauthors
Biscetti F,Nardella E,Cecchini AL,Landolfi R,Flex Adoi
10.1155/2019/4128682subject
Has Abstractpub_date
2019-05-08 00:00:00pages
4128682eissn
0962-9351issn
1466-1861journal_volume
2019pub_type
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journal_title:Mediators of inflammation
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journal_title:Mediators of inflammation
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pub_type: 临床试验,杂志文章
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pub_type: 已发布勘误
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journal_title:Mediators of inflammation
pub_type: 杂志文章
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journal_title:Mediators of inflammation
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Mediators of inflammation
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pub_type: 杂志文章
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更新日期:2005-12-14 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Mediators of inflammation
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journal_title:Mediators of inflammation
pub_type: 杂志文章
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