Heterogeneous nuclear ribonucleoprotein C binds exclusively to the functionally important UUUUU-motifs in the human papillomavirus type-1 AU-rich inhibitory element.

abstract：:Porcine reproductive and respiratory syndrome (PRRS) is a major disease affecting pigs worldwide and resulting in considerable economic losses. While PRRS is a global phenomenon, the causative viruses PRRSV-1 (first detected in Europe) and PRRSV-2 (isolated in North America) are genetically and biologically distinct. ...

journal_title：Virus research

authors： Salguero FJ,Frossard JP,Rebel JM,Stadejek T,Morgan SB,Graham SP,Steinbach F

更新日期：2015-04-16 00:00:00

abstract：:The glycoprotein (G) is the only surface protein of the lyssavirus particle and the only viral product known to be capable of eliciting the production of neutralizing antibodies. In this study, the isolation of escape mutants resistant to monoclonal antibody (Mab) neutralization was attempted by a selection strategy e...

journal_title：Virus research

authors： Fallahi F,Wandeler AI,Nadin-Davis SA

更新日期：2016-07-15 00:00:00

abstract：:Herpesvirus, such as herpes simplex type 1 (HSV-1) acquire their envelope by budding through a modified inner membrane of the nuclear envelope which forms thick and dense patches at the site of budding. This suggests that some of the viral envelope glycoproteins must be transported to the nuclear envelope in order to ...

journal_title：Virus research

authors： Gilbert R,Ghosh HP

更新日期：1993-06-01 00:00:00

abstract：:Primers corresponding to conserved regions in the RNA-dependent RNA polymerase and the RACE procedure led to the cloning of the complete sweetpotato mild mottle virus (SPMMV) RNA genome. The assembled SPMMV genomic sequence was 10,818 nucleotides in length with a polyadenylated tract at the 3' terminus. The structure ...

journal_title：Virus research

authors： Colinet D,Kummert J,Lepoivre P

更新日期：1998-02-01 00:00:00

abstract：:The interaction between UV-B irradiation and cutaneous human papillomaviruses (HPV) has been suggested to be of relevance for the development of non-melanoma skin cancers. We investigated the activity within the upstream regulatory region (URR) of the HPV types 8, 38, 92, 93 and 96, as well as their responsiveness to ...

journal_title：Virus research

authors： Vasiljević N,Nielsen L,Doherty G,Dillner J,Forslund O,Norrild B

更新日期：2008-11-01 00:00:00

abstract：:The goal of this review is to summarize recently published epidemiological information that contribute to understanding the natural history of cervical and human papillomavirus (HPV) infection and their associated lesions among human immunodeficiency virus (HIV) infected women and men. HIV-positive women and men are m...

journal_title：Virus research

authors： de Sanjosé S,Palefsky J

更新日期：2002-11-01 00:00:00

abstract：:Viruses and virus-like particles (VLPs) of insect parasitoids modify host-parasite interactions. The Drosophila wasp, Leptopilina heterotoma, produce 300 nm spiked VLPs that bind to the host's blood cells via surface projections. L. heterotoma is a generalist wasp that attacks over a dozen Drosophila species. Oviposit...

journal_title：Virus research

authors： Gueguen G,Rajwani R,Paddibhatla I,Morales J,Govind S

更新日期：2011-09-01 00:00:00

abstract：:Oryctes rhinoceros nudivirus (OrNV) has been an effective biocontrol agent against the insect pest Oryctes rhinoceros (Coleoptera: Scarabaeidae) for decades, but there is evidence that resistance could be evolving in some host populations. We detected OrNV infection in O. rhinoceros from Solomon Islands and used Oxfor...

journal_title：Virus research

authors： Etebari K,Filipović I,Rašić G,Devine GJ,Tsatsia H,Furlong MJ

更新日期：2020-03-01 00:00:00

abstract：:RNA species of plant tripartite RNA viruses show distinct translational activities in vitro when the viral RNA concentration is high. However, it is not known what causes the differential translation of virion RNAs. Using an in vitro wheat germ translation system, we investigated the translation efficiencies and compe...

journal_title：Virus research

authors： Kwon CS,Chung WI

更新日期：2000-02-01 00:00:00

abstract：:Borna disease virus grows to low titres in persistently infected cells with an infectious particle to cell ratio of 0.01 to 0.05. Inclusion of n-butyrate in the growth medium enhances infectivity yields up to 1 log. This effect is time and concentration dependent. In hypertonic medium with an excess of NaCl, KCl or Na...

journal_title：Virus research

authors： Pauli G,Ludwig H

更新日期：1985-02-01 00:00:00

abstract：:The morbidity and mortality of coxsackievirus A10 (CVA10)-associated hand, foot, and mouth disease (HFMD) have been increasing in recent years, while few studies on the vaccine and animal model of CVA10 have been reported. Here, we first established a CVA10-infected gerbil model and employed it to evaluate the immunop...

journal_title：Virus research

authors： Chen C,Xia Y,Zhu S,Xu F,Sun Y,Lu H,Gao M,Yang Z,Mao Z,Ge Q,Miao Z,Zhu H,Yao P

更新日期：2020-09-01 00:00:00

abstract：:A recent study has shown that the reovirus lambda1 protein can unwind double-stranded nucleic acid molecules, a process energetically coupled to the hydrolysis of nucleoside 5'-triphosphates. In the present study, it was demonstrated that lambda1, expressed as a fusion protein with the Escherichia coli maltose-binding...

journal_title：Virus research

authors： Bisaillon M,Lemay G

更新日期：1997-10-01 00:00:00

abstract：:In the past few decades, dengue has spread rapidly and is an emerging disease in China. An unexpected dengue outbreak occurred in Xishuangbanna, Yunnan, China, resulting in 1331 patients in 2013. In order to obtain the complete genome information and perform mutation and evolutionary analysis of causative agent relate...

journal_title：Virus research

authors： Wang X,Ma D,Huang X,Li L,Li D,Zhao Y,Qiu L,Pan Y,Chen J,Xi J,Shan X,Sun Q

更新日期：2017-06-15 00:00:00

abstract：:The capsid structures of the 7 serotypes of foot-and-mouth disease virus have been compared utilizing a series of neutralizing monoclonal antibodies which were previously shown to recognize at least 4 distinct epitopes on type A12 virus. A radioimmune binding assay using radioactively labeled antigens and the monoclon...

journal_title：Virus research

authors： Grubman MJ,Morgan DO

更新日期：1986-10-01 00:00:00

abstract：:We have recently identified and sequenced a molecular clone of the serogroup 2 simian retrovirus (SRV), D2/RHE/OR/V1, that retains an enhanced ability to infect specific T cell lines. In this report, using deletion mutagenesis, we localized the psi packaging signal, necessary for packaging of D2/RHE/OR/V1 particles, t...

journal_title：Virus research

authors： Li B,Nguyen S,Li X,Machida CA

更新日期：2001-06-01 00:00:00

abstract：:Rhabdoviruses cause devastating diseases in aquaculture, resulting in enormous economic losses. Our previous studies indicated that imidazole arctigenin derivatives possessed antiviral activities against aquatic rhabdoviruses. Based on the data of structure-activity relationship, a new imidazole arctigenin derivative,...

journal_title：Virus research

authors： Shen YF,Liu YH,Li BY,Liu TQ,Wang GX

更新日期：2020-08-01 00:00:00

abstract：:Equine herpesvirus type 1 and 4 (EHV-1 and EHV-4) are important pathogens of horses worldwide. Infection with EHV-4 usually remains restricted to the upper respiratory tract, whereas infection with EHV-1 can generalize after leukocyte-associated viremia. Here we examined whether differences in the immunomodulatory gly...

journal_title：Virus research

authors： Thormann N,Van de Walle GR,Azab W,Osterrieder N

更新日期：2012-10-01 00:00:00

abstract：:The generation of a new panel of 32 monoclonal antibodies (MAbs) reactive with the P protein of the raccoon strain of rabies virus is described. Through a series of analyses employing competitive ELISA and immunoblotting, these MAbs were classified into eight groups, each defining an antigenic site, thereby increasing...

journal_title：Virus research

authors： Nadin-Davis SA,Fehlner-Gardiner C,Sheen M,Wandeler AI

更新日期：2010-09-01 00:00:00

abstract：:Quasispecies dynamics mediates adaptability of RNA viruses through a number of mechanisms reviewed in the present article, with emphasis on the medical implications for the hepatitis viruses. We discuss replicative and non-replicative molecular mechanisms of genome variation, modulating effects of mutant spectra, and ...

journal_title：Virus research

authors： Domingo E,Gomez J

更新日期：2007-08-01 00:00:00

abstract：:The hepatitis C virus (HCV) nonstructural protein 3 (NS3) is essential for the processing of the HCV polyprotein, the replication of HCV RNA, and to short circuit innate immunity signaling. NS3 contains an N-terminal domain with protease activity and a C-terminal domain with helicase activity. The two domains communic...

journal_title：Virus research

authors： Vaughan R,Li Y,Fan B,Ranjith-Kumar CT,Kao CC

更新日期：2012-10-01 00:00:00

abstract：:Puumala (PUU) virus causes a form of hemorrhagic fever with renal syndrome (HFRS), called nephropathia epidemica (NE), in Europe. HFRS is characterized by an increased capillary permeability, which we hypothesize is caused by hyperactivation of the host immune system, especially cellular immune responses. To identify ...

journal_title：Virus research

authors： Terajima M,Van Epps HL,Li D,Leporati AM,Juhlin SE,Mustonen J,Vaheri A,Ennis FA

更新日期：2002-03-20 00:00:00

abstract：:The sub-cellular location and mechanism of membrane association of NS3 and NS2-3 polypeptides of bovine viral diarrhoea virus (BVDV) have been examined. Both NS3 and NS2-3 proteins were detected in post-nuclear membrane fractions but not in cytosolic fractions of BVDV infected cells; a proportion of NS3, but not NS2-3...

journal_title：Virus research

authors： Zhang G,Flick-Smith H,McCauley JW

更新日期：2003-11-01 00:00:00

abstract：:Peste-des-petits-ruminants virus (PPRV) (family Paramyxoviridae, genus Morbillivirus) causes an acute febrile illness in sheep and goats resulting in significant morbidity and mortality in infected herds. The paramyxoviruses all have negative sense, non-segmented RNA genomes and their host range and pathogenic determi...

journal_title：Virus research

authors： Bailey D,Chard LS,Dash P,Barrett T,Banyard AC

更新日期：2007-06-01 00:00:00

abstract：:The BKRF2, BKRF3 and BKRF4 genes of Epstein-Barr virus (EBV) are located close together in the viral genome, which encode glycoprotein L, uracil-DNA glycosylase and a tegument protein, respectively. Here, we demonstrate that the BKRF2 gene behaves as a true-late lytic gene, whereas the BKRF3 and BKRF4 genes belong to ...

journal_title：Virus research

authors： Chen LW,Hung CH,Wang SS,Yen JB,Liu AC,Hung YH,Chang PJ

更新日期：2018-09-02 00:00:00

abstract：:It has recently been reported that the xenotropic murine leukemia virus-related virus (XMRV) derives from a laboratory recombinant. However, sequences with characteristics of the 5' half of XMRV (termed PreXMRV-2) have been identified in several laboratory mouse genomes and cell lines suggesting parts of the XMRV geno...

journal_title：Virus research

authors： Mayer J,Mazzoni CJ,Greenwood AD

更新日期：2012-10-01 00:00:00

abstract：:A cDNA of the glycoprotein (G protein) gene of rabies virus Nishigahara strain was cloned and inserted into a baculovirus genome under the control of the polyhedrin promoter. Infection of Spodoptera frugiperda cells with this recombinant virus produced a large quantity of new protein instead of the parental polyhedrin...

journal_title：Virus research

authors： Tuchiya K,Matsuura Y,Kawai A,Ishihama A,Ueda S

更新日期：1992-09-01 00:00:00

abstract：:Highly pathogenic avian H5N1 influenza A viruses occasionally infect humans and cause severe respiratory disease and fatalities. Currently, these viruses are not efficiently transmitted from person to person, although limited human-to-human transmission may have occurred. Nevertheless, further adaptation of avian H5N1...

journal_title：Virus research

authors： Imai M,Herfst S,Sorrell EM,Schrauwen EJ,Linster M,De Graaf M,Fouchier RA,Kawaoka Y

更新日期：2013-12-05 00:00:00

abstract：:Viruses are most frequently discovered because they cause disease. To expand knowledge of plant-associated viruses beyond these narrow constraints, non-cultivated plants of the Tallgrass Prairie of the United States were systematically surveyed for evidence of viruses. This report discusses putative viruses of the fam...

journal_title：Virus research

authors： Thapa V,Melcher U,Wiley GB,Doust A,Palmer MW,Roewe K,Roe BA,Shen G,Roossinck MJ,Wang YM,Kamath N

更新日期：2012-07-01 00:00:00

abstract：:Lepidopteran nucleopolyhedroviruses have distinct viral tissue tropisms in host larvae. We previously identified the Bm8 gene of Bombyx mori nucleopolyhedrovirus (BmNPV), the product of which inhibits viral propagation in the middle silk gland (MSG). However, it is unknown whether this inhibitory function of the Bm8 p...

journal_title：Virus research

authors： Hikida H,Kokusho R,Kobayashi J,Shimada T,Katsuma S

更新日期：2018-04-02 00:00:00

abstract：:Inhibition of the function of the M2 protein by amantadine can cause a conformational change in the haemagglutinin (HA) of H7 influenza A viruses and the consequent expression of the low pH form of the glycoprotein on the surface of virus-infected cells. Immunofluorescence studies showed that this conversion occurs sh...

journal_title：Virus research

authors： Ciampor F,Thompson CA,Grambas S,Hay AJ

更新日期：1992-03-01 00:00:00