Abstract：
:Exhaustive information on the Epstein-Barr virus, a member of the herpes family, is described at the International Herpes Management Forum web-site. Cervical cancer associations, AIDS treatment projects, and the Los Alamos National Laboratories provide useful information on papillomavirus infections, as well as hyperlinks to recent international papillomavirus conferences. A private pharmaceutical company, in collaboration with the National Institutes of Health, has launched a lively web-site covering different aspects of microbial infections for the general public.
journal_name
Microbes Infectjournal_title
Microbes and infectionauthors
Kotra LP,Ojcius DMdoi
10.1016/s1286-4579(00)01308-3subject
Has Abstractpub_date
2000-10-01 00:00:00pages
1537issue
12eissn
1286-4579issn
1769-714Xpii
S1286-4579(00)01308-3journal_volume
2pub_type
杂志文章abstract：:Measles and pertussis are ubiquitous vaccine-preventable diseases, which remain an important public health problem in developing countries. Hence, developing a deep understanding of their transmission dynamics remains imperative. To achieve this, we compared the impact of vaccination at both individual and population ...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2004.12.018
更新日期：2005-04-01 00:00:00
abstract：:Macrophages respond to infection with Legionella pneumophila by the induction of inflammatory mediators, including type I Interferons (IFN-Is). To explore whether the bacterial second messenger cyclic 3'-5' diguanylate (c-diGMP) activates some of these mediators, macrophages were infected with L. pneumophila strains i...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2011.09.002
更新日期：2012-02-01 00:00:00
abstract：:Comparative genomics and microarrays reveal that the genomes of different Salmonella enterica serovars are distinguished from each other by the presence or absence of hundreds of genes. The distribution of these variable genome regions is often not clonal. Therefore, lateral gene transfer (LGT) plays an important role...
journal_title：Microbes and infection
pub_type： 杂志文章,评审
doi：10.1016/s1286-4579(03)00186-2
更新日期：2003-09-01 00:00:00
abstract：:In this paper we evaluate the role of human γδ T cells in control of Francisella tularensis infection. Using an in vitro model of infection, a reduction in bacterial numbers was detected in the presence of human γδ T cells for both attenuated LVS and virulent SCHU S4 strains of F. tularensis. Antibody neutralisation o...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2012.02.001
更新日期：2012-07-01 00:00:00
abstract：:Cytolytic T-cell responses from 63 normal blood donors were monitored in a Mycobacterium bovis BCG infection system in vitro. We wanted to know whether cultured dendritic cells were capable of potentiating the cytolytic T-cell responses to M. bovis BCG. Infected cultured dendritic cells were up to ten times more effec...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/s1286-4579(99)80077-x
更新日期：1999-08-01 00:00:00
abstract：:Human immunodeficiency virus type 1 (HIV-1) mostly owes its success to its ability to evade host immune responses. Understanding viral immune escape mechanisms is a prerequisite to improve future HIV-1 vaccine design. This review focuses on the strategies that HIV-1 has evolved to evade recognition by natural killer (...
journal_title：Microbes and infection
pub_type： 杂志文章,评审
doi：10.1016/j.micinf.2012.05.001
更新日期：2012-09-01 00:00:00
abstract：:Evaluation of vector control is crucial for improving malaria containment and, according to World Health Organization, new complementary indicators would be very valuable. In this study the IgG response to the Anopheles-specific cE5 salivary protein was tested as a tool to evaluate the efficacy of insecticide-treated ...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2015.01.002
更新日期：2015-06-01 00:00:00
abstract：:Staphylococcus aureus is an important cause of skin infections. We recently described an outbreak of recurrent furunculosis involving methicillin-resistant S. aureus among mentally retarded adults. We sought to determine the role of impaired neutrophil functions in its pathogenesis. Blood neutrophil functions were det...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2006.02.019
更新日期：2006-06-01 00:00:00
abstract：:Pseudomonas aeruginosa, a significant cause of human morbidity and mortality, uses a type 3 secretion system (T3SS) to inject effector toxins into host cells. We previously reported that P. aeruginosa uses ADP-ribosyltransferase (ADPr) activity of the T3SS effector ExoS for intracellular replication. T3SS translocon (...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2012.08.007
更新日期：2012-12-01 00:00:00
abstract：:Filifactor alocis, a previously unrecognized Gram-positive anaerobic rod, is now considered a new emerging pathogen that may play a significant role in periodontal disease. F. alocis' unique characteristics and variations at the molecular level that may be responsible for the functional changes required to mediate the...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2015.03.011
更新日期：2015-07-01 00:00:00
abstract：:Despite high vaccination coverage, pertussis remains an important respiratory infectious disease and the least-controlled vaccine-preventable infectious disease in children. Natural infection with Bordetella pertussis is known to induce strong and long-lasting immunity that wanes later than vaccine-mediated immunity. ...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2013.10.002
更新日期：2014-01-01 00:00:00
abstract：:Neisseria meningitidis is an opportunistic human pathogen that usually colonizes the nasopharyngeal mucosa asymptomatically. Upon invasion into the blood and central nervous system, this bacterium triggers a fulminant inflammatory reaction with the manifestations of septicemia and meningitis, causing high morbidity an...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2015.09.025
更新日期：2016-02-01 00:00:00
abstract：:Vibrio vulnificus is capable of causing severe and often fatal infections in susceptible individuals. It causes two distinct disease syndromes, a primary septicemia and necrotizing wound infections. This review discusses the interaction of environmental conditions, host factors, and bacterial virulence determinants th...
journal_title：Microbes and infection
pub_type： 杂志文章,评审
doi：10.1016/s1286-4579(00)00270-7
更新日期：2000-02-01 00:00:00
abstract：:We previously showed that human corneal epithelial cells (HCECs) express Toll-like receptors (TLRs), which recognize gram-positive bacteria and respond to Staphylococcus aureus infection by the expression and secretion of proinflammatory cytokines and beta-defensin-2 (hBD2). In this study, we further elucidated the un...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2005.07.006
更新日期：2006-02-01 00:00:00
abstract：:Tonsilloliths are a potential cause of oral malodor. In this study, microbial profiles and composition of tonsilloliths were determined using culture-independent molecular methods and scanning electron microscopy. 16S ribosomal RNA bacterial genes (16S rDNAs) isolated from tonsilloliths of 6 individuals were amplified...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2006.04.023
更新日期：2006-08-01 00:00:00
abstract：:Microsporidia are intracellular pathogens that cause severe disease in immunocompromised humans and animals. We recently demonstrated that XID mice are more susceptible to Encephalitozoon cuniculi infection by intraperitoneal route, evidencing the role of B-1 cells in resistance against infection. The present study in...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2017.11.004
更新日期：2018-03-01 00:00:00
abstract：:Experimental cutaneous leishmaniasis is a useful model in studying the mechanism regulating immune responses between T helper type 1 (Th1) and Th2. Mice susceptible to Leishmania major infection such as BALB/c (H-2(d)) are associated with the induction of the disease-promoting Th2 response, while the resistant mice su...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/s1286-4579(00)01298-3
更新日期：2000-10-01 00:00:00
abstract：:Black rats (Rattus rattus) receiving Leishmania tropica injected intradermally into the ear were studied for the persistence of parasites and infectivity to natural sand fly vector. The mammalian host, the parasite, and the vector all originated from the endemic focus of Urfa, Turkey. Rats did not develop lesions or a...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/s1286-4579(03)00046-7
更新日期：2003-04-01 00:00:00
abstract：:Our previous study has demonstrated that IL-10 may modulate both indoleamine 2,3-dioxygenase (IDO) and CD163 expression in lepromatous leprosy (LL) cells, favoring Mycobacterium leprae persistence through induction of regulatory pathways and iron storage. Here, we observed that in LL lesion cells there is an increase ...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2017.06.006
更新日期：2017-11-01 00:00:00
abstract：:Infection with Brucella abortus induces a pro-inflammatory response that drives T cell responses toward a Th1 profile. The mechanism by which this bacterium triggers this response is unknown. Dendritic cells (DC) are crucial mediators at the host-pathogen interface and are potent Th1-inducing antigen-presenting cells....
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2008.07.035
更新日期：2008-10-01 00:00:00
abstract：:Effective vaccines against infectious diseases and biological warfare agents remain an urgent public health priority. Studies have characterized the differentiation of effector and memory T cells and identified a subset of T cells capable of conferring enhanced protective immunity against pathogen challenge. We hypoth...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2007.07.009
更新日期：2007-10-01 00:00:00
abstract：:We investigated the relationship between antibody response to the major Paracoccidioides brasiliensis antigen, a 43-kDa glycoprotein, and the two paracoccidioidomycosis (PCM) clinical presentations, the juvenile and the adult forms. Total immunoglobulin G (IgG), IgG isotypes, and IgA anti-gp43 antibodies were determin...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/s1286-4579(99)80022-7
更新日期：1999-04-01 00:00:00
abstract：:Several pathogens including Gram-negative bacteria hijack complement regulators to escape host's innate response. Pathogenic Leptospira species bind Factor H, C4b binding protein and vitronectin from the complement system. We evaluated the ability of low passage (LP) and culture-attenuated (CA) pathogenic strains of L...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2019.03.001
更新日期：2019-01-01 00:00:00
abstract：:The manipulation hypothesis states a parasite may alter host behaviour for its own benefit, often by enhancing its transmission rate through the food chain. This paper reviews studies on the potential impact of one parasite, Toxoplasma gondii, on host behaviour, both on rodents, where altered responses may be proposed...
journal_title：Microbes and infection
pub_type： 杂志文章,评审
doi：10.1016/s1286-4579(01)01459-9
更新日期：2001-10-01 00:00:00
abstract：:Streptococcus pneumoniae is a major pathogen causing potentially life-threatening community-acquired diseases in both the developed and developing world. Since 1967, there has been a dramatic increase in the incidence of penicillin-resistant and multiply antibiotic-resistant pneumococci worldwide. Prevention of access...
journal_title：Microbes and infection
pub_type： 杂志文章,评审
doi：10.1016/s1286-4579(00)01345-9
更新日期：2000-12-01 00:00:00
abstract：:To obtain monkey-tropic viruses that are more closely related to HIV-1 than the original NL-DT5/NL-DT5R clones, we constructed six vif-chimeric and two site-specific vif-mutant viruses, and examined their growth ability. Different from NL-DT5/NL-DT5R, these viruses did not grow in monkey cells. We monitored the capabi...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2008.06.007
更新日期：2008-08-01 00:00:00
abstract：:Isolates of Toxoplasma gondii, which is responsible for a wide range of clinical manifestations are grouped into three clonal lineages of different virulence in mice. However, it is not clear whether this genotypic pattern is associated with the clinical profile of the disease in humans nor is the geographical distrib...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2006.03.023
更新日期：2006-08-01 00:00:00
abstract：:Most pandemic influenza virus strains undergo adaptation or reassortment before they acquire the ability to cause fatal infections in a new host species. The pathologic changes and tissue tropism during virus adaptation are not fully understood. Here we investigated pathologic changes and tissue tropism by serial lung...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/j.micinf.2008.09.013
更新日期：2009-01-01 00:00:00
abstract：:Anaerobic bacteria can cause a variety of endogenous infections in children. Because of their fastidious nature, they are difficult to isolate from infectious sites, and are often overlooked. Anaerobic infections can occur in all body sites, including the central nervous system, oral cavity, head and neck, chest, abdo...
journal_title：Microbes and infection
pub_type： 杂志文章,评审
doi：10.1016/s1286-4579(02)01656-8
更新日期：2002-10-01 00:00:00
abstract：:Paracoccidioides brasiliensis is a dimorphic fungus known to produce invasive systemic disease in humans. The 43-kDa glycoprotein of P. brasiliensis is the major diagnostic antigen of paracoccidioidomycosis and may act as a virulence factor, since it is a receptor for laminin.Very little is known about early interacti...
journal_title：Microbes and infection
pub_type： 杂志文章
doi：10.1016/s1286-4579(00)00390-7
更新日期：2000-07-01 00:00:00
