Serotyping of Toxoplasma gondii in chronically infected pregnant women: predominance of type II in Europe and types I and III in Colombia (South America).

abstract：:Mucosal epithelia constitute the first barriers to be overcome by pathogens during infection. The induction of protective IgA in this location is important for the prevention of infection and can be achieved through different mucosal immunization strategies. Lactic acid bacteria have been tested in the last few years ...

journal_title：Microbes and infection

authors： Oliveira ML,Arêas AP,Campos IB,Monedero V,Perez-Martínez G,Miyaji EN,Leite LC,Aires KA,Lee Ho P

更新日期：2006-04-01 00:00:00

abstract：:We investigated the relationship between antibody response to the major Paracoccidioides brasiliensis antigen, a 43-kDa glycoprotein, and the two paracoccidioidomycosis (PCM) clinical presentations, the juvenile and the adult forms. Total immunoglobulin G (IgG), IgG isotypes, and IgA anti-gp43 antibodies were determin...

journal_title：Microbes and infection

authors： Baida H,Biselli PJ,Juvenale M,Del Negro GM,Mendes-Giannini MJ,Duarte AJ,Benard G

更新日期：1999-04-01 00:00:00

abstract：:Malaria is an infectious disease caused by parasites of the genus Plasmodium. This intraerythrocytic protozoan produces hemozoin (HZ), an insoluble crystalline metabolite resulting from the heme detoxification mechanism. This review will focus on HZ biosynthesis and synthetic preparation, but in particular on its effe...

journal_title：Microbes and infection

authors： Shio MT,Kassa FA,Bellemare MJ,Olivier M

更新日期：2010-11-01 00:00:00

abstract：:Microsporidia are intracellular pathogens that cause severe disease in immunocompromised humans and animals. We recently demonstrated that XID mice are more susceptible to Encephalitozoon cuniculi infection by intraperitoneal route, evidencing the role of B-1 cells in resistance against infection. The present study in...

journal_title：Microbes and infection

authors： Langanke Dos Santos D,Alvares-Saraiva AM,Xavier JG,Spadacci-Morena DD,Peres GB,Dell'Armelina Rocha PR,Perez EC,Lallo MA

更新日期：2018-03-01 00:00:00

abstract：:Francisella tularensis subspecies (subsp.) tularensis is a CDC Category A biological warfare agent and inhalation of as few as 15 bacilli can initiate severe disease. Relatively little is known about the cellular and molecular mechanisms of host defense against respiratory infection with subsp. tularensis. In this stu...

journal_title：Microbes and infection

authors： KuoLee R,Harris G,Conlan JW,Chen W

更新日期：2011-05-01 00:00:00

abstract：:Foot-and-mouth disease virus (FMDV) is a member of the Aphthovirus genus in the Picornaviridae family. Seven distinct serotypes, each including a wide range of variants, have been defined. FMD, affects wild and domesticated ruminants and pigs, is difficult to control and is the major constraint to international trade ...

journal_title：Microbes and infection

authors： Alexandersen S,Zhang Z,Donaldson AI

更新日期：2002-08-01 00:00:00

abstract：:Burkholderia pseudomallei is a major cause of bacterial septicemias in many parts of the world, particularly Thailand; the known geographic range of the organism appears to be enlarging as awareness of the organism and the disease it causes--melioidosis--increases. B. pseudomallei is intrinsically resistant to most an...

journal_title：Microbes and infection

authors： Woods DE,DeShazer D,Moore RA,Brett PJ,Burtnick MN,Reckseidler SL,Senkiw MD

更新日期：1999-02-01 00:00:00

abstract：:The early interferon-gamma (IFN-gamma) response after Salmonella infection was compared in resistant and susceptible congenic mice strains differing by the allele of Nramp1. IFN-gamma gene expression in vivo was studied by quantitative reverse transcription-PCR performed from the spleen of mice challenged by Salmonell...

journal_title：Microbes and infection

authors： Lalmanach AC,Montagne A,Menanteau P,Lantier F

更新日期：2001-07-01 00:00:00

abstract：:C/EBPbeta plays a pivotal role in activation of human immunodeficiency virus type 1 (HIV-1) in monocytes/macrophages. However, mechanisms for functional regulation of C/EBPbeta remain uncharacterized. Previous studies indicated that NF-kappaB activation by tumor necrosis factor (TNF) receptor family, which activates T...

journal_title：Microbes and infection

authors： Horie R,Ishida T,Maruyama-Nagai M,Ito K,Watanabe M,Yoneyama A,Higashihara M,Kimura S,Watanabe T

更新日期：2007-05-01 00:00:00

abstract：:Multilocus enzyme electrophoresis (MLEE) is the gold standard for taxonomy and strain typing of Leishmania, but has some limitations. An alternative reliable and fast genotyping method for addressing population genetic and key epidemiological questions, is multilocus microsatellite typing (MLMT). MLMT using 15 markers...

journal_title：Microbes and infection

authors： Kuhls K,Keilonat L,Ochsenreither S,Schaar M,Schweynoch C,Presber W,Schönian G

更新日期：2007-03-01 00:00:00

abstract：:Toll-like receptors recognize specific patterns of microbial components and regulate the activation of both innate and adaptive immunity. TLR4 recognizes lipopolysaccharide (LPS) in monocytes/macrophages with the help of other molecules like CD14 and MD-2, which indicates that the functional LPS receptor forms a large...

journal_title：Microbes and infection

authors： Moreno C,Merino J,Ramírez N,Echeverría A,Pastor F,Sánchez-Ibarrola A

更新日期：2004-09-01 00:00:00

abstract：:Entamoeba histolytica, which causes amebic colitis and occasional liver abscesses in humans, can induce host cell death through apoptosis and necrosis. Recently, we have demonstrated that E. histolytica can induce cell death in neutrophils via diphenyleneiodonium-sensitive NADPH oxidase (NOX)-derived reactive oxygen s...

journal_title：Microbes and infection

authors： Kim KA,Kim JY,Lee YA,Song KJ,Min D,Shin MH

更新日期：2011-11-01 00:00:00

abstract：:Long-term protection against Toxoplasma gondii is dependent on robust CD8(+) T cell immunity. In the absence of this response, the host is unable to maintain chronicity, which results in recrudescence of infection and possible death. Factors needed for the persistence of protective CD8(+) T cells against the parasite ...

journal_title：Microbes and infection

authors： Bhadra R,Khan IA

更新日期：2012-11-01 00:00:00

abstract：:Campylobacter jejuni and Campylobacter coli together represent the leading bacterial cause of human enteritis. However, the pathogenesis of this disease is poorly understood. Infection results in the formation of crypt abscesses resulting from the migration of neutrophils across the intestinal epithelium and into the ...

journal_title：Microbes and infection

authors： Murphy H,Cogan T,Humphrey T

更新日期：2011-01-01 00:00:00

abstract：:Helicobacter pylori infection induces chronic inflammation in the gastric mucosa with a marked increase in the number of lymphoid follicles consisting of infiltrating B and T cells, neutrophils, dendritic cells (DC) and macrophages. It has been suggested that an accumulation of mature DC in the tissue, resulting from ...

journal_title：Microbes and infection

authors： Hansson M,Lundgren A,Elgbratt K,Quiding-Järbrink M,Svennerholm AM,Johansson EL

更新日期：2006-03-01 00:00:00

abstract：:Two strains of mice selected according to extreme phenotypes of susceptibility and resistance to oral tolerance (TS and TR mice, respectively) were infected with 1 x 10(7) Leishmania amazonensis promastigotes and studied comparatively. TS mice developed a minor pathology while permitting parasite growth with the prese...

journal_title：Microbes and infection

authors： Tavares D,da Conceição Ribeiro R,Carlos da Silva A

更新日期：2006-04-01 00:00:00

abstract：:We previously showed the possibility that Gag A146P, which is an escape mutant from HLA-B∗57-restricted CTLs, was selected by HLA-B∗48:01-restricted Gag138-147(LI10)-specific CTLs in a Japanese cohort in which HLA-B∗57 individuals were not detected. We herein demonstrated Gag140-147(GI8) to be the optimal epitope rath...

journal_title：Microbes and infection

authors： Naruto T,Murakoshi H,Chikata T,Koyanagi M,Kawashima Y,Gatanaga H,Oka S,Takiguchi M

更新日期：2011-08-01 00:00:00

abstract：:Toxin B, an exotoxin produced by the anaerobic Gram-positive bacteria Clostridium difficile, is responsible for pseudomembranous colitis in humans. It deeply modifies morphology of cultured cells and enhances their membrane surface area, which suggests a possible alteration of membrane receptor distribution. Since tox...

journal_title：Microbes and infection

authors： Siffert JC,Müller CD,Dumont S,Monteil H,Poindron P

更新日期：1999-12-01 00:00:00

abstract：:Infection of colonic epithelial cells by Shigella is associated with the type III secretion system, which serves as a molecular syringe to inject effectors into host cells. This system includes an extracellular needle used as a conduit for secreted proteins. Two of these proteins, IpaB and IpaD, dock at the needle tip...

journal_title：Microbes and infection

authors： Meghraoui A,Schiavolin L,Allaoui A

更新日期：2014-07-01 00:00:00

abstract：:Our previous study has demonstrated that IL-10 may modulate both indoleamine 2,3-dioxygenase (IDO) and CD163 expression in lepromatous leprosy (LL) cells, favoring Mycobacterium leprae persistence through induction of regulatory pathways and iron storage. Here, we observed that in LL lesion cells there is an increase ...

journal_title：Microbes and infection

authors： de Mattos Barbosa MG,da Silva Prata RB,Andrade PR,Ferreira H,de Andrade Silva BJ,da Paixão de Oliveira JA,Assis TQ,de Toledo-Pinto TG,de Lima Bezerra OC,da Costa Nery JA,Rosa PS,Bozza MT,Lara FA,Moraes MO,Schmitz V,Sarno EN

更新日期：2017-11-01 00:00:00

abstract：:We have previously reported that mice immunized with the mycobacterial 27-kDa lipoprotein were more susceptible to Mycobacterium tuberculosis (Mtb) challenge. We also showed that 27-kDa lipoprotein abrogated the protection afforded by the BCG vaccine when administrated together, suggesting that the 27-kDa lipoprotein ...

journal_title：Microbes and infection

authors： Hovav AH,Mullerad J,Maly A,Davidovitch L,Fishman Y,Bercovier H

更新日期：2006-06-01 00:00:00

abstract：:Infection with Trypanosoma cruzi, the etiologic agent in Chagas disease, may result in heart disease. Over the last decades, Chagas disease endemic areas in Latin America have seen a dietary transition from the traditional regional diet to a Western style, fat rich diet. Previously, we demonstrated that during acute i...

journal_title：Microbes and infection

authors： Lizardo K,Ayyappan JP,Cui MH,Balasubramanya R,Jelicks LA,Nagajyothi JF

更新日期：2019-01-01 00:00:00

abstract：:Neisseria meningitidis, an exclusive pathogen of humans, remains the leading worldwide cause of meningitis and fatal sepsis, usually in otherwise healthy individuals. In recent years, significant advances have improved our understanding of the epidemiology and genetic basis of meningococcal disease and led to progress...

journal_title：Microbes and infection

authors： Tzeng YL,Stephens DS

更新日期：2000-05-01 00:00:00

abstract：:Afipia felis is a Gram-negative alpha-proteobacterium, a rare cause of human cat scratch disease (CSD), and likely a pathogen of amoeba. Here, we show that various members of the genus Afipia attach to and are taken up by various non-professional phagocytic mammalian cells (epithelial CHO, endothelial EA.hy926, epithe...

journal_title：Microbes and infection

authors： Schueller C,Schneider B,Kempf VA,Haas A

更新日期：2007-03-01 00:00:00

abstract：:The Escherichia coli NleH1 and NleH2 virulence proteins differentially regulate host transcription of innate immunity genes. The mouse pathogen Citrobacter rodentium encodes one NleH protein, which functions equivalently to E. coli NleH1. We examined the impact of host genetics and intestinal inflammation on the contr...

journal_title：Microbes and infection

authors： Feuerbacher LA,Hardwidge PR

更新日期：2014-05-01 00:00:00

abstract：:The differentiation and survival of developing alpha beta thymocytes depends on effective T-cell receptor (TCR) signaling upon recognition of self peptide/major histocompatibility complex (MHC) molecule ligands. Although this concept is uniformly accepted with regard to immature thymocytes, there are conflicting repor...

journal_title：Microbes and infection

authors： Dorfman JR,Germain RN

更新日期：2002-04-01 00:00:00

abstract：:The innate immune system detects the presence of microbes through different families of pattern-recognition receptors (PRRs). PRRs detect pathogens of all origins and trigger signaling events that activate innate and adaptive immunity. These events need to be tightly regulated in order to ensure optimal activation whe...

journal_title：Microbes and infection

authors： Odendall C,Kagan JC

更新日期：2017-01-01 00:00:00

abstract：:Immature dendritic cells (Dcs) are characterised by high antigen uptake ability and poor T-cell stimulatory function. In contrast, mature DCs have a high stimulatory function and poor antigen uptake ability. Inflammatory stimuli induce DC maturation and migration from nonlymphoid tissues to lymphoid organs. We investi...

journal_title：Microbes and infection

authors： Granucci F,Ferrero E,Foti M,Aggujaro D,Vettoretto K,Ricciardi-Castagnoli P

更新日期：1999-11-01 00:00:00

abstract：:In human blood, promastigotes bind natural antibodies and activate the classical complement pathway. C3-opsonized promastigotes immune-adhere within seconds to erythrocytes. Promastigote lysis by complement parallels C3 deposition kinetics, and ~90% of promastigotes are killed after 2.5 min. During infection, compleme...

journal_title：Microbes and infection

authors： Domínguez M,Moreno I,Aizpurua C,Toraño A

更新日期：2003-05-01 00:00:00

abstract：:Experimental cutaneous leishmaniasis is a useful model in studying the mechanism regulating immune responses between T helper type 1 (Th1) and Th2. Mice susceptible to Leishmania major infection such as BALB/c (H-2(d)) are associated with the induction of the disease-promoting Th2 response, while the resistant mice su...

journal_title：Microbes and infection

authors： Nashed BF,Maekawa Y,Takashima M,Zhang T,Ishii K,Dainichi T,Ishikawa H,Sakai T,Hisaeda H,Himeno K

更新日期：2000-10-01 00:00:00