Functional genomics in Arabidopsis: large-scale insertional mutagenesis complements the genome sequencing project.

Abstract:

:The ultimate goal of genome research on the model flowering plant Arabidopsis thaliana is the identification of all of the genes and understanding their functions. A major step towards this goal, the genome sequencing project, is nearing completion; however, functional studies of newly discovered genes have not yet kept up to this pace. Recent progress in large-scale insertional mutagenesis opens new possibilities for functional genomics in Arabidopsis. The number of T-DNA and transposon insertion lines from different laboratories will soon represent insertions into most Arabidopsis genes. Vast resources of gene knockouts are becoming available that can be subjected to different types of reverse genetics screens to deduce the functions of the sequenced genes.

journal_name

Curr Opin Biotechnol

authors

Parinov S,Sundaresan V

doi

10.1016/s0958-1669(00)00075-6

subject

Has Abstract

pub_date

2000-04-01 00:00:00

pages

157-61

issue

2

eissn

0958-1669

issn

1879-0429

pii

S0958-1669(00)00075-6

journal_volume

11

pub_type

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