Abstract:
:Bioindustry is expanding to an increasing variety of food, chemical and pharmaceutical products, each requiring rapid development of a dedicated cell factory and bioprocess. Microfluidic tools are, together with tools from synthetic biology and metabolic modeling, being employed in cell factory and bioprocess development to speed up development and address new products. Recent examples of microfluidics for bioprocess development range from integrated devices for DNA assembly and transformation, to high throughput screening of cell factory libraries, and micron scale bioreactors for process optimization. These improvements act to improve the biotechnological engineering cycle with tools for building, testing and evaluating cell factories and bioprocesses by increasing throughput, parallelization and automation.
journal_name
Curr Opin Biotechnoljournal_title
Current opinion in biotechnologyauthors
Bjork SM,Joensson HNdoi
10.1016/j.copbio.2018.08.011subject
Has Abstractpub_date
2019-02-01 00:00:00pages
95-102eissn
0958-1669issn
1879-0429pii
S0958-1669(18)30055-7journal_volume
55pub_type
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