Plastid biotechnology: prospects for herbicide and insect resistance, metabolic engineering and molecular farming.

Abstract:

:Transgene expression from the chloroplast (plastid) genome offers several attractions to plant biotechnologists, including high-level accumulation of foreign proteins, transgene stacking in operons and a lack of epigenetic interference with the stability of transgene expression. In addition, the technology provides an environmentally benign method of plant genetic engineering, because plastids and their genetic information are maternally inherited in most crops and thus are largely excluded from pollen transmission. During the past few years, researchers in both the public and private sectors have begun to explore possible areas of application of plastid transformation in plant biotechnology as a viable alternative to conventional nuclear transgenic technologies. Recent proof-of-concept studies highlight the potential of plastid genome engineering for the expression of resistance traits, the production of biopharmaceuticals and metabolic pathway engineering in plants.

journal_name

Curr Opin Biotechnol

authors

Bock R

doi

10.1016/j.copbio.2006.12.001

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

100-6

issue

2

eissn

0958-1669

issn

1879-0429

pii

S0958-1669(06)00168-6

journal_volume

18

pub_type

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