Abstract:
:The use of ultrafast laser pulses in surgery has allowed for unprecedented precision with minimal collateral damage to surrounding tissues. For these reasons, ultrafast laser nanosurgery, as an injury model, has gained tremendous momentum in experimental biology ranging from in vitro manipulations of subcellular structures to in vivo studies in whole living organisms. For example, femtosecond laser nanosurgery on such model organism as the nematode Caenorhabditis elegans has opened new opportunities for in vivo nerve regeneration studies. Meanwhile, the development of novel microfluidic devices has brought the control in experimental environment to the level required for precise nanosurgery in various animal models. Merging microfluidics and laser nanosurgery has recently improved the specificities and increased the speed of laser surgeries enabling fast genome-wide screenings that can more readily decode the genetic map of various biological processes.
journal_name
Curr Opin Biotechnoljournal_title
Current opinion in biotechnologyauthors
Ben-Yakar A,Bourgeois Fdoi
10.1016/j.copbio.2009.01.008subject
Has Abstractpub_date
2009-02-01 00:00:00pages
100-5issue
1eissn
0958-1669issn
1879-0429pii
S0958-1669(09)00010-Xjournal_volume
20pub_type
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journal_title:Current opinion in biotechnology
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journal_title:Current opinion in biotechnology
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