Novel approaches in food-processing technology: new technologies for preserving foods and modifying function.

abstract：:Due to its enormous relevance the corona formation of adsorbed proteins around nanoparticles is widely investigated. A comparison of different experimental techniques is given. Direct measurements of proteins, such as typically performed with mass spectrometry, will be compared with indirect analysis, in which instead...

journal_title：Current opinion in biotechnology

authors： Carrillo-Carrion C,Carril M,Parak WJ

更新日期：2017-08-01 00:00:00

abstract：:To mitigate some of the potentially deleterious environmental and agricultural consequences associated with current land-based-biofuel feedstocks, we propose the use of biofuels derived from aquatic microbial oxygenic photoautotrophs (AMOPs), more commonly known as cyanobacteria, algae, and diatoms. Herein we review t...

journal_title：Current opinion in biotechnology

authors： Dismukes GC,Carrieri D,Bennette N,Ananyev GM,Posewitz MC

更新日期：2008-06-01 00:00:00

abstract：:Bioindustry is expanding to an increasing variety of food, chemical and pharmaceutical products, each requiring rapid development of a dedicated cell factory and bioprocess. Microfluidic tools are, together with tools from synthetic biology and metabolic modeling, being employed in cell factory and bioprocess developm...

journal_title：Current opinion in biotechnology

authors： Bjork SM,Joensson HN

更新日期：2019-02-01 00:00:00

abstract：:Mismatch-repair systems have been identified in organisms ranging from Escherichia coli to humans. They can repair almost all DNA base pair mismatches as well as small insertion/deletion mismatches. Molecular and biochemical analyses have shown that the core components of eukaryotic mismatch-repair systems are highly ...

journal_title：Current opinion in biotechnology

authors： Kolodner RD,Alani E

更新日期：1994-12-01 00:00:00

abstract：:Our ability to dissect and understand the principles of gene regulatory circuits is partly limited by the resolution of our experimental assays. In this brief review, we discuss aspects of gene expression in microbial organisms apparent only when increasing the experimental resolution from populations to single cells ...

journal_title：Current opinion in biotechnology

authors： Wallden M,Elf J

更新日期：2011-02-01 00:00:00

abstract：:Fluorescent proteins (FPs) and fluorescent protein-derived biosensors are indispensable tools in life sciences. They make it possible to probe the location, activity, or interaction of molecules of interest from a subcellular to a multicellular scale. The desire for high-resolution and multidimensional information imp...

journal_title：Current opinion in biotechnology

authors： Duwé S,Dedecker P

更新日期：2019-08-01 00:00:00

abstract：:Organic chemistry has systematically probed the chemical determinants of function in nucleic acids by variation to the nucleobase, sugar ring and backbone moieties to build synthetic genetic polymers. Concomitantly, protein engineering has advanced to allow the discovery of polymerases capable of utilizing modified nu...

journal_title：Current opinion in biotechnology

authors： Houlihan G,Arangundy-Franklin S,Holliger P

更新日期：2017-12-01 00:00:00

abstract：:The increase in quality, quantity, and complexity of recombinant products heavily drives the need to predictably engineer model and complex (mammalian) cell systems. However, until recently, limited tools offered the ability to precisely manipulate their genomes, thus impeding the full potential of rational cell line ...

journal_title：Current opinion in biotechnology

authors： Cheng JK,Alper HS

更新日期：2014-12-01 00:00:00

abstract：:Intraportal islet transplantation has emerged as a promising treatment for type 1 diabetes mellitus (T1DM). Nevertheless, long-term efficacy has been limited to a marginal number of patients. Outcomes have been restricted, in part, by challenges associated with the transplant site, poor vascularization, and disruption...

journal_title：Current opinion in biotechnology

authors： Coronel MM,Stabler CL

更新日期：2013-10-01 00:00:00

abstract：:Significant new advances at the molecular level in the field of plant-pathogen interactions form the basis for novel transgenic approaches to crop protection. The cloning of disease resistance genes and the dissection of the signal transduction components of the hypersensitive response and systemic acquired resistance...

journal_title：Current opinion in biotechnology

authors： Shah DM

更新日期：1997-04-01 00:00:00

abstract：:Constructing novel biological systems that function in a robust and predictable manner requires better methods for discovering new functional molecules and for optimizing their assembly in novel biological contexts. By enabling functional diversification and optimization in the absence of detailed mechanistic understa...

journal_title：Current opinion in biotechnology

authors： Dougherty MJ,Arnold FH

更新日期：2009-08-01 00:00:00

abstract：:Naturally occurring microbial consortia have been utilized in a variety of bioremediation processes. Recent developments in molecular microbial ecology offer new tools that facilitate molecular analyses of microbial populations at contaminated and bioremediated sites. Information provided by such analyses aids in the ...

journal_title：Current opinion in biotechnology

authors： Watanabe K

更新日期：2001-06-01 00:00:00

abstract：:Lactococcus lactis is the primary model organism for lactic acid bacteria (LAB) and is widely used in the production of fermented dairy products. In recent years there has been increasing interest in strains isolated from non-dairy environments, as these exhibit a high metabolic diversity and have unique flavour-formi...

journal_title：Current opinion in biotechnology

authors： van Hylckama Vlieg JE,Rademaker JL,Bachmann H,Molenaar D,Kelly WJ,Siezen RJ

更新日期：2006-04-01 00:00:00

abstract：:Endoproteolytic cleavage of hormone and neuropeptide precursors, as well as many complex proteins, such as coagulation factors and viral glycoproteins, is a key process in the generation of bioactive polypeptides. These cleavages typically occur at the dibasic amino acid residues Lys-Arg or Arg-Arg. The enzymes respon...

journal_title：Current opinion in biotechnology

authors： Rehemtulla A,Kaufman RJ

更新日期：1992-10-01 00:00:00

abstract：:Heterotrophic bacteria are an integral part of any environmental biotechnology process (EBP). Therefore, factors controlling bacterial abundance, activity, and community composition are central to the understanding of such processes. Among these factors, top-down control by bacteriophage predation has so far received ...

journal_title：Current opinion in biotechnology

authors： Shapiro OH,Kushmaro A

更新日期：2011-06-01 00:00:00

abstract：:Starting from experimental data on sequence, structure or biochemical properties of enzymes, protein design seeks to construct enzymes with desired activity, stability, specificity and selectivity. Two strategies are widely used to investigate sequence-structure-function relationships: statistical methods to analyse p...

journal_title：Current opinion in biotechnology

authors： Pleiss J

更新日期：2011-10-01 00:00:00

abstract：:Autonomous vehicles are becoming an essential tool in a wide range of environmental applications that include ambient data acquisition, remote sensing, and mapping of the spatial extent of pollutant spills. Among these applications, pollution source localization has drawn increasing interest due to its scientific and ...

journal_title：Current opinion in biotechnology

authors： Bayat B,Crasta N,Crespi A,Pascoal AM,Ijspeert A

更新日期：2017-06-01 00:00:00

abstract：:Advances in metabolic engineering have given rise to the biological production of novel fuels and chemicals, but yields are often low without significant optimization. One generalizable solution is to create a specialized organelle for the sequestration of engineered metabolic pathways. Bacterial microcompartments are...

journal_title：Current opinion in biotechnology

authors： Kim EY,Tullman-Ercek D

更新日期：2013-08-01 00:00:00

abstract：:Mitochondria are both morphologically and functionally diverse, and this variety is thought to have important biological ramifications. The development of methods to probe the properties of individual mitochondria is therefore of utmost importance. Recent advances have been made using in situ microscopy techniques and...

journal_title：Current opinion in biotechnology

authors： Fuller KM,Arriaga EA

更新日期：2003-02-01 00:00:00

abstract：:During the past decade, the increasing knowledge of flavonoid biosynthesis and the important function of flavonoid compounds in plants and in human and animal nutrition have made the biosynthetic pathways to flavonoids and isoflavonoids excellent targets for metabolic engineering. Recent strategies have included intro...

journal_title：Current opinion in biotechnology

authors： Forkmann G,Martens S

更新日期：2001-04-01 00:00:00

abstract：:Patient-derived xenografts (PDXs) are obtained by transplanting fragments of a patient's tumour into immunodeficient mice. Growth and propagation of PDXs allows correlating therapeutic response in vivo with extensive, multi-dimensional molecular annotation, leading to identification of predictive biomarkers. PDXs are ...

journal_title：Current opinion in biotechnology

authors： Invrea F,Rovito R,Torchiaro E,Petti C,Isella C,Medico E

更新日期：2020-06-01 00:00:00

abstract：:Yeast, especially Saccharomyces cerevisiae and Pichia pastoris, are major hosts employed in the expression of authentic heterologous proteins of high quality in the biopharmaceutical, industrial and academic environments. There has been recent progress in characterizing and controlling the factors involved in determin...

journal_title：Current opinion in biotechnology

authors： Eckart MR,Bussineau CM

更新日期：1996-10-01 00:00:00

abstract：:Enormous fuel consumption and growing environmental concerns have been spurring development of renewable biofuels. Among various biofuels, fatty acid-derived biohydrocarbons are ideal alternatives to non-renewable fossil fuels due to their closest properties to petroleum-based fuels. In the past decade, novel hydrocar...

journal_title：Current opinion in biotechnology

authors： Liu K,Li S

更新日期：2020-04-01 00:00:00

abstract：:Synthetic proteins provide important information about the principles of protein structure. They illuminate the processes of natural protein evaluation, but are not limited by these processes. Here, we review studies of several mutant proteins and discuss the general principles that can be derived from them. ...

journal_title：Current opinion in biotechnology

authors： Pastore A,Lesk AM

更新日期：1991-08-01 00:00:00

abstract：:Transdifferentiation of one cell type to another has garnered significant research efforts in recent years. As cardiomyocyte loss following myocardial infarction becomes debilitating for cardiac patients, the option of an autologous source of cardiomyocytes not derived from multi/pluripotent stem cell sources is an at...

journal_title：Current opinion in biotechnology

authors： Monaghan MG,Holeiter M,Layland SL,Schenke-Layland K

更新日期：2016-08-01 00:00:00

abstract：:Many recent advances in bioreporter technology focus on challenges related to bioengineering, yet in many applications implementation of optical signal measurement is equally susceptible to improvement. For bioluminescent bioreporters, one area of effort lies in the development of semiconductor chip-based detector mod...

journal_title：Current opinion in biotechnology

authors： Wells M

更新日期：2006-02-01 00:00:00

abstract：:Stable isotopes are flexibly used as tracers to investigate environmental processes, microorganisms responsible for environmental transformations, syntrophic relationships in consortia, and metabolic pathways. With the advent of widely accessible high-resolution, highly accurate and sensitive mass spectrometers connec...

journal_title：Current opinion in biotechnology

authors： Adrian L,Marco-Urrea E

更新日期：2016-10-01 00:00:00

abstract：:Global aquaculture is projected to grow from 10 million to 20 million metric tons by the year 2000. To meet this projection, the aquaculture industry must bring some of its infectious disease problems under control without relying on antibiotics and chemotherapeutics. Thus, vaccines for fish and shellfish are being so...

journal_title：Current opinion in biotechnology

authors： Leong JA

更新日期：1993-06-01 00:00:00

abstract：:The quantification of intracellular fluxes via 13C metabolic flux analysis has become one of the major techniques to support systems-based metabolic engineering of industrial production hosts. Commonly, 13C studies are conducted using minimal media, however, a great variety of industrial processes rely on complex medi...

journal_title：Current opinion in biotechnology

authors： Schwechheimer SK,Becker J,Wittmann C

更新日期：2018-12-01 00:00:00

abstract：:Transgene expression from the chloroplast (plastid) genome offers several attractions to plant biotechnologists, including high-level accumulation of foreign proteins, transgene stacking in operons and a lack of epigenetic interference with the stability of transgene expression. In addition, the technology provides an...

journal_title：Current opinion in biotechnology

authors： Bock R

更新日期：2007-04-01 00:00:00