Cloning of E6 and E7 genes of human papilloma virus type 18 and transformation potential of E7 gene and its mutants.

abstract：:Watermelon mosaic virus (WMV) is one of the most important viruses that causes different symptoms in Cucurbitaceae. WMV is a potyvirus with a worldwide distribution, but occurs most commonly in temperate and Mediterranean regions. Cucurbit species grown in Yazd, Esfahan, West Azerbaijan, Hormozgan, and Kerman province...

journal_title：Virus genes

authors： Sharifi M,Massumi H,Heydarnejad J,Hosseini Pour A,Shaabanian M,Rahimian H

更新日期：2008-12-01 00:00:00

abstract：:The envelope proteins of Chikungunya virus (CHIKV) are known to play crucial roles in viral infection and spread. Although the role of envelope proteins in viral infection has been studied, the cellular interactors of these proteins are still elusive. In the present study, the ectodomains of CHIKV envelope proteins (E...

journal_title：Virus genes

authors： Dudha N,Rana J,Rajasekharan S,Gabrani R,Gupta A,Chaudhary VK,Gupta S

更新日期：2015-04-01 00:00:00

abstract：:The immunity of a combined DNA vaccine of HSV-2 glycoproteins B2 (gB2) and D2 (gD2) genes in comparison to individual vaccines was studied with regard to protecting against the HSV infection. Two recombinant DNA vaccines of the pHS2-gB2 or pHS2-gD2 were constructed and formulated. The neutralizing antibody titers appe...

journal_title：Virus genes

authors： Lee HH,Cha SC,Jang DJ,Lee JK,Choo DW,Kim YS,Uh HS,Kim SY

更新日期：2002-10-01 00:00:00

abstract：:Chinese equine infectious anemia virus (EIAV) attenuated vaccine is the first lentiviral vaccine with a successful application. In order to understand the correlation of viral genomic mutations with viral attenuation and with induced immunoprotective properties, we analyzed the proviral genome sequences of the EIAV-at...

journal_title：Virus genes

authors： Qi X,Wang X,Wang S,Lin Y,Jiang C,Ma J,Zhao L,Lv X,Shen R,Wang F,Kong X,Su Z,Zhou J

更新日期：2010-08-01 00:00:00

abstract：:In this study, a novel duplex nanoparticle-assisted polymerase chain reaction (nanoPCR) assay was developed to detect porcine epidemic diarrhea virus (PEDV) and porcine transmissible gastroenteritis virus (TGEV). Two pairs of primers were designed based on the conserved region within the N gene of PEDV and TGEV. In a ...

journal_title：Virus genes

authors： Zhu Y,Liang L,Luo Y,Wang G,Wang C,Cui Y,Ai X,Cui S

更新日期：2017-02-01 00:00:00

abstract：:Twenty-three CSFV isolates recovered from field outbreaks in various parts of India during 2006-2009 were used for genetic analysis in the NS5B region (409 nts). Seventeen of these were studied earlier [16] in the 5'UTR region. Phylogenetic analysis indicated the continued dominance of subgroup 1.1 strains in the coun...

journal_title：Virus genes

authors： Patil SS,Hemadri D,Veeresh H,Sreekala K,Gajendragad MR,Prabhudas K

更新日期：2012-02-01 00:00:00

abstract：:Recent studies show that human skin at homeostasis is a complex ecosystem whose virome include circular DNA viruses, especially papillomaviruses and polyomaviruses. To determine the chicken skin virome in comparison with human skin virome, a chicken swabs pool sample from fifteen indoor healthy chickens of five geneti...

journal_title：Virus genes

authors： Denesvre C,Dumarest M,Rémy S,Gourichon D,Eloit M

更新日期：2015-10-01 00:00:00

abstract：:The major immunogenic protein VP2 from a pathogenic field isolate (variant A virus) of infectious bursal disease virus (IBDV) was cloned and sequenced to examine antigenic variations. The VP2 open reading frame consists of 1509 nucleotides and codes for a 503 amino acid protein. Overall, the VP2 amino acid sequence of...

journal_title：Virus genes

authors： Lana DP,Beisel CE,Silva RF

更新日期：1992-08-01 00:00:00

abstract：:The nucleotide sequence of the genome segment (S6) encoding the nonstructural protein NS1 of an Australian isolate of bluetongue virus serotype 20 (BTV 20) has been determined from a series of overlapping cDNA clones synthesized using two terminal 15-mer oligonucleotides as primers. The gene consists of 1769 nucleotid...

journal_title：Virus genes

authors： Cowley JA

更新日期：1992-11-01 00:00:00

abstract：:Proteins harbor domains or short linear motifs, which facilitate their functions and interactions. Finding functional motifs in protein sequences could predict the putative cellular roles or characteristics of hypothetical proteins. In this study, we present Shetti-Motif, which is an interactive tool to (i) map UniPro...

journal_title：Virus genes

authors： Sobhy H

更新日期：2017-04-01 00:00:00

abstract：:Emerging pseudorabies virus (PRV) variant has led to frequent outbreaks of PRV infection among Bartha-K61-vaccinated swine population in Chinese swine farms and caused high mortality in pigs of all age since late 2011. Here, we generated a gE/gI-deleted PRV (rPRVXJ-delgI/gE-EGFP) based on PRV variant strain (PRV-XJ) t...

journal_title：Virus genes

authors： Yin Y,Xu Z,Liu X,Li P,Yang F,Zhao J,Fan Y,Sun X,Zhu L

更新日期：2017-08-01 00:00:00

abstract：:This study focuses on gene expression of porcine circovirus (PCV) in order to identify viral genes and their corresponding mRNA transcripts. By northern blot analysis, the existence of three mRNAs could be demonstrated. Two mRNAs are encoded by the viral (-)-strand and one is encoded by the viral (+)-strand. The (+)-s...

journal_title：Virus genes

authors： Mankertz J,Buhk HJ,Blaess G,Mankertz A

更新日期：1998-01-01 00:00:00

abstract：:We evaluated the predicted biochemical properties of Gag proteins from a diverse group of feline immunodeficiency viruses (FIV) to determine how different evolutionary histories of virus and host have changed or constrained these important structural proteins. Our data are based on FIV sequences derived from domestic ...

journal_title：Virus genes

authors： Burkala E,Poss M

更新日期：2007-10-01 00:00:00

abstract：:The genomes (188 kbp) of the prototype Molluscum contagiosum virus type 1 (MCV-1) and a variant strain (MCV-1v) were characterized by construction of the physical maps of the viral DNA for the restriction enzymes BamHI, ClaI, EcoRI, and HindIII using a defined gene library harboring the DNA sequences of the MCV-1 geno...

journal_title：Virus genes

authors： Bugert J,Rösen-Wolff A,Darai G

更新日期：1989-11-01 00:00:00

abstract：:Mokola virus, one of the six genotypes within the Lyssavirus genus of the Rhabdoviridae family, is believed to be exclusive to the African continent, where infections in various mammal species have been reported. After an isolation of Mokola virus at Umhlanga on the east coast of South Africa in 1970, the virus was no...

journal_title：Virus genes

authors： Nel L,Jacobs J,Jaftha J,von Teichman B,Bingham J,Olivier M

更新日期：2000-01-01 00:00:00

abstract：:Recently, NADC30-like porcine reproductive and respiratory syndrome viruses (PRRSVs), which are genetically similar to the NADC30 strain isolated in the United States of America in 2008, have become prevalent in China. Here, a novel variant PRRSV strain named HNhx was successfully isolated on porcine alveolar macropha...

journal_title：Virus genes

authors： Wang LJ,Wan B,Guo Z,Qiao S,Li R,Xie S,Chen XX,Zhang G

更新日期：2018-02-01 00:00:00

abstract：:Enterovirus 96 (EV-96) is a recently described member of the species Enterovirus C and is associated with paralysis and myelitis. In this study, using metagenomic sequencing, we identified a new enterovirus 96 strain (EV-96-SZ/GD/CHN/2014) as the sole pathogen causing hand, foot, and mouth disease (HFMD). A genomic co...

journal_title：Virus genes

authors： Xu Y,Sun Y,Ma J,Zhou S,Fang W,Ye J,Tan L,Ji J,Luo D,Li L,Li J,Fang C,Pei N,Shi S,Liu X,Jiang H,Gong S,Xu X

更新日期：2017-06-01 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer associated with the Merkel cell polyomavirus (MCPyV). The MCPyV genome, which is clonally integrated in the majority of MCCs, encodes the regulatory small T (sT) antigen. Previously, reports have established MCPyV sT antigen as a potent onco...

journal_title：Virus genes

authors： Wu JH,Simonette RA,Nguyen HP,Rady PL,Tyring SK

更新日期：2016-06-01 00:00:00

abstract：:The establishment of viral pathogens in new host environments following spillover events probably requires adaptive changes within both the new host and pathogen. After many generations, signals for ancient cross-species transmission may become lost and a strictly host-adapted phylogeny may mimic true co-divergence wh...

journal_title：Virus genes

authors： Das S,Smith K,Sarker S,Peters A,Adriaanse K,Eden P,Ghorashi SA,Forwood JK,Raidal SR

更新日期：2019-12-01 00:00:00

abstract：:Exfoliative toxin A (ETA)-coding temperate bacteriophages are leading contributors to the toxic phenotype of impetigo strains of Staphylococcus aureus. Two distinct eta gene-positive bacteriophages isolated from S. aureus strains which recently caused massive outbreaks of pemphigus neonatorum in Czech maternity hospit...

journal_title：Virus genes

authors： Botka T,Růžičková V,Konečná H,Pantůček R,Rychlík I,Zdráhal Z,Petráš P,Doškař J

更新日期：2015-08-01 00:00:00

abstract：:Bacteriophage T7 RNA polymerase and a derivative containing a nuclear localization signal were transiently expressed in CV-1 cells and were shown to localize to the cytoplasm and nucleus, respectively. A vector was constructed containing T7 promoter and transcription terminator sequences flanking a picornaviral 5' unt...

journal_title：Virus genes

authors： Wilk T,Mierswa H,Kräusslich HG,Dunn JJ,Bosch V

更新日期：1992-08-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome (PRRS) is a swine disease of major economic importance that causes reproductive and respiratory problems in pigs. In the present study, one strain of porcine reproductive and respiratory syndrome virus (PRRSV) was isolated in Xinjiang province, Northwest China, designated ...

journal_title：Virus genes

authors： Xia J,Chen S,Huang J,Ma W,Du W,Yang X,Liu Y,Yan G

更新日期：2015-02-01 00:00:00

abstract：:Mal de Río Cuarto virus (MRCV) is a newly described species of the genus Fijivirus, family Reoviridae. Compared with other plant-infecting genus of the family, the function and localization of MRCV and other Fijivirus proteins are poorly understood. Through analysis of viral particle purifications, we positively ident...

journal_title：Virus genes

authors： Distéfano AJ,Maldonado S,Hopp HE,del Vas M

更新日期：2009-06-01 00:00:00

abstract：:A goose parvovirus (GPV) Y strain was isolated from Muscovy ducks in Anhui Province of China. By polymerase chain reaction method, its complete genomic sequence was found to be 5,106 bp in length, consisting of 444-bp inverted terminal repeat, 1,844-bp non-structural protein and 2,199-bp capsid protein (VP) regions. T...

journal_title：Virus genes

authors： Liu HM,Wang H,Tian XJ,Zhang S,Zhou XH,Qi KZ,Pan L

更新日期：2014-02-01 00:00:00

abstract：:The presence of Cucumber mosaic virus (CMV) satellite RNA dramatically changes symptoms on some hosts. A satellite RNA present in a strain of CMV (PepY-CMV) that induced chlorosis in pepper (Capsicum annuum) was shown to induce chlorosis in pepper in combination with another strain (Fny-CMV) that by itself induced a g...

journal_title：Virus genes

authors： Choi SK,Jeon YW,Yoon JY,Choi JK

更新日期：2011-08-01 00:00:00

abstract：:The red imported fire ant (Solenopsis invicta) escaped its natural enemies when it was introduced into North America in the 1930s from South America. US efforts have focused on discovery of natural enemies, like viruses, to provide sustainable control of the ant. Nine new virus genomes were sequenced from the invasive...

journal_title：Virus genes

authors： Valles SM,Rivers AR

更新日期：2019-06-01 00:00:00

abstract：:The eight gene segments of avian influenza virus (AIV) reassort frequently and rapidly to generate novel genotypes and subtypes that are transmissible to a broad range of hosts. There is evidence that AIV can have a restricted host range and can segregate in space and time. Host-virus relationships at the species, geo...

journal_title：Virus genes

authors： Girard YA,Runstadler JA,Aldehoff F,Boyce W

更新日期：2012-06-01 00:00:00

abstract：:Statistically significant sequence similarity was revealed between the gene A32 product of vaccinia virus (VV), gene I products (gpI) of filamentous single-stranded DNA bacteriophages, and IVa2 gene products of adenoviruses. Four conserved sequence motifs were delineated, the two N-proximal of which correspond to the ...

journal_title：Virus genes

authors： Koonin EV,Senkevich TG,Chernos VI

更新日期：1993-02-01 00:00:00

abstract：:The baculovirus system was used to express the X protein of human hepatitis B virus (HBV). The X open reading frames (X ORFs) from cloned viral DNA of the HBV subtypes ayw and adr were introduced into the genome of Autographa californica nuclear polyhedrosis virus (AcNPV). The HBV-DNA of subtype adr derived from a hep...

journal_title：Virus genes

authors： Klein R,Schröder CH,Zentgraf H

更新日期：1991-04-01 00:00:00

abstract：:Human spuma retrovirus (HSRV) belongs to retroviruses that possess a complex genome organization. HSRV carries at least three extra genes in the region between env and the 3' long terminal repeat, which are not found in simple retroviruses. Via alternative splicing, these HSRV genes can encode several proteins. To gen...

journal_title：Virus genes

authors： Adachi A,Sakai H,Tokunaga K,Kawamura M

更新日期：1995-01-01 00:00:00