CreA modulates the XlnR-induced expression on xylose of Aspergillus niger genes involved in xylan degradation.

Abstract:

:The expression of the feruloyl esterase gene faeA, the alpha-glucuronidase gene aguA, the endoxylanase gene xlnB, and the beta-xylosidase gene xlnD from Aspergillus niger on xylose was studied in a wild-type strain and in a CreA mutant. A decrease in expression of all four genes was observed with increasing xylose concentrations in the wild-type strain, whereas expression levels in the CreA mutant were not influenced. The results in the wild type indicated that xylose concentrations higher than 1 mM resulted in repression of the expression of the xylanolytic genes tested mediated by the carbon catabolite repressor protein CreA. On xylose, the expression levels of the xylanolytic genes were therefore not only determined by induction via XlnR, but also by repression via CreA. The genes tested were not influenced to the same extent by XlnR or CreA, resulting in specific expression levels and patterns for each individual gene.

journal_name

Res Microbiol

journal_title

Research in microbiology

authors

de Vries RP,Visser J,de Graaff LH

doi

10.1016/s0923-2508(99)80053-9

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

281-5

issue

4

eissn

0923-2508

issn

1769-7123

pii

S0923250899800539

journal_volume

150

pub_type

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