The human vaginal microbial community.

Abstract:

:Monopolization of the vaginal econiche by a limited number of Lactobacillus species, resulting in low pH of 3.5-4.5, has been shown to protect women against vaginal dysbiosis, sexually transmitted infections and adverse pregnancy outcomes. Still, controversy exists as to which characteristics of lactobacilli are most important with regard to colonization resistance and to providing protection. This review addresses the antimicrobial and anti-inflammatory roles of lactic acid (and low pH) and hydrogen peroxide (and oxidative stress) as means of lactobacilli to dominate the vaginal econiche.

journal_name

Res Microbiol

journal_title

Research in microbiology

authors

Vaneechoutte M

doi

10.1016/j.resmic.2017.08.001

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

811-825

issue

9-10

eissn

0923-2508

issn

1769-7123

pii

S0923-2508(17)30133-X

journal_volume

168

pub_type

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