Monitoring of Bordetella isolates circulating in Saint Petersburg, Russia between 2001 and 2009.

Abstract:

:Bordetella isolates in the Saint Petersburg region have been monitored since 1998. Over the past ten years, concomitant with the increase in pertussis whole-cell vaccine coverage, the incidence of whooping cough has decreased. However, this decrease exists only for Bordetella pertussis infections, as the incidence of Bordetella parapertussis confirmed cases has remained stable, suggesting that pertussis-vaccine-induced immunity is not protective against parapertussis, as expected. B. pertussis and B. parapertussis clinical isolates were analyzed using serotyping, immunoblotting, pulsed-field gel electrophoresis of chromosomal DNA (after digestion with XbaI) and sequencing of virulence genes. The bacterial population is now similar to that observed in other European countries.

journal_name

Res Microbiol

journal_title

Research in microbiology

authors

Kurova N,Njamkepo E,Brun D,Tseneva G,Guiso N

doi

10.1016/j.resmic.2010.09.013

subject

Has Abstract

pub_date

2010-12-01 00:00:00

pages

810-5

issue

10

eissn

0923-2508

issn

1769-7123

pii

S0923-2508(10)00208-1

journal_volume

161

pub_type

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