Abstract：
:In this study, we identified an antimicrobial compound produced by the Gram-negative bacterium Serratia marcescens. Colonies of S. marcescens inhibited the growth of nine different methicillin-resistant Staphylococcus aureus (MRSA) isolates and several other tested Gram-positive bacterial species, but not Gram-negative bacteria. Genetic analysis revealed the requirement for the swrW gene which codes for a non-ribosomal peptide synthetase that generates the cyclodepsipeptide antibiotic serratamolide, also known as serrawettin W1. This is the first report describing the anti-MRSA properties of serratamolide.
journal_name
Res Microbioljournal_title
Research in microbiologyauthors
Kadouri DE,Shanks RMdoi
10.1016/j.resmic.2013.06.002keywords:
["Aminolipid","Antibiotic","MRSA","Non-ribosomal peptide synthetase","Nosocomial infection","Secondary metabolite"]subject
Has Abstractpub_date
2013-10-01 00:00:00pages
821-6issue
8eissn
0923-2508issn
1769-7123pii
S0923-2508(13)00103-4journal_volume
164pub_type
杂志文章abstract：:For nearly one hundred years, researchers have attempted to categorize botulinum neurotoxin-producing clostridia and the toxins that they produce according to biochemical characterizations, serological comparisons, and genetic analyses. Throughout this period the bacteria and their toxins have defied such attempts at ...
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pub_type： 历史文章,杂志文章,评审
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abstract：:A Gram-negative, short rod, aerobic bacterium, designated W11(T), was isolated from seawater. Heterotrophic growth was observed at 10-45 °C and pH 6-10. Optimal growth was observed at 30-37 °C and pH 7-9. It can grow in the presence of 0.5-12% NaCl (w/v), and the optimal NaCl required for growth was 5-6%. 16S rRNA gen...
journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/j.resmic.2014.07.008
更新日期：2014-09-01 00:00:00
abstract：:Spirochetes have a unique motility system that is characterized by flagellar filaments contained within the outer membrane sheath. Direct evidence using video microscopy has recently been obtained which indicates that these periplasmic flagella (PF) rotate in several spirochetal species. This rotation generates thrust...
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pub_type： 杂志文章,评审
doi：10.1016/0923-2508(92)90117-7
更新日期：1992-07-01 00:00:00
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journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/j.resmic.2016.05.004
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abstract：:Sequences of the most conserved proteins encoded by transposable (pro)phages were used to search recently sequenced Firmicute genomes for candidate transposable prophages. One complete Mu-like prophage, SglyMu-1, was identified, in four copies, in the Syntrophobotulus glycolicus DSM 8271 chromosome sequence. Related p...
journal_title：Research in microbiology
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abstract：:The interest of probiotics as remedies for a broad number of gastrointestinal and other infectious diseases has gained wide interest over the last few years, but little is known about their underlying mechanism of action. In this study, the probiotic activities of a human isolate of Lactobacillus casei subsp. rhamnosu...
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doi：10.1016/s0923-2508(01)01188-3
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journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/j.resmic.2004.04.004
更新日期：2004-09-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.resmic.2016.06.010
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journal_title：Research in microbiology
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doi：10.1016/j.resmic.2009.01.001
更新日期：2009-04-01 00:00:00
abstract：:Bacteria of the genus Klebsiella are important opportunistic pathogens responsible for nosocomial infections that are increasingly resistant to antimicrobial agents. Distinctive identification of the species K. oxytoca, K. pneumoniae, K. planticola, K. ornithinolytica and K. terrigena is difficult based on phenotypic ...
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更新日期：2003-10-01 00:00:00
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journal_title：Research in microbiology
pub_type： 杂志文章,评审
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journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/s0923-2508(99)80032-1
更新日期：1999-03-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/S0923-2508(99)80064-3
更新日期：1997-11-01 00:00:00
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journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/j.resmic.2014.04.005
更新日期：2014-07-01 00:00:00
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journal_title：Research in microbiology
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doi：10.1016/j.resmic.2015.05.001
更新日期：2015-11-01 00:00:00
abstract：:It has been suggested that, in rod-shaped bacteria, two sites for peptidoglycan assembly exist: one which is responsible for septum formation and the other, for lateral wall extension. The balance between the activities of these two sites enables bacteria to conserve their own morphology during cell growth. The effect...
journal_title：Research in microbiology
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doi：10.1016/S0923-2508(97)81895-5
更新日期：1997-01-01 00:00:00
abstract：:The structure of spiroplasmas in the Chinese mitten crab associated with tremor disease was studied by transmission electron microscopy techniques, including both negative staining and ultrasectioning. A spiral structure, which is a typical form of spiroplasmas, could be detected and the observations showed for the fi...
journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/j.resmic.2004.04.010
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abstract：:A total of 28 species of Legionella could be differentiated by rRNA gene restriction patterns generated after cleavage of total DNA with either EcoRV or HindIII restriction endonucleases, and hybridization of fragments with 32P-labelled Escherichia coli 16 + 23S rRNA. Different species gave different fragment patterns...
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doi：10.1016/0923-2508(89)90193-9
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abstract：:By employing flow cytometry, the DNA content and cell size of individual bacterial cells may be determined rapidly and with high precision. Also, the number of DNA replication origins in Escherichia coli cells can be measured after treating the cells with rifampicin together with the cell division inhibitor cephalexin...
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journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/0923-2508(89)90078-8
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journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/j.resmic.2017.12.006
更新日期：2018-04-01 00:00:00
abstract：:Although this volume is dedicated to honoring François Jacob, I would like my contribution to broaden the context by recalling the background within which the scientists of those times operated. The specific scientific accomplishments of Jacob will certainly be covered by the other contributors who collaborated with h...
journal_title：Research in microbiology
pub_type： 传,历史文章,杂志文章
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abstract：:Replicon typing is the identification of plasmids by hybridization with specific DNA probes which contain the genes involved in plasmid maintenance. This new method has been used to classify plasmids into replicon (rep) groups which can often be correlated with incompatibility (Inc) groups. We studied 71 multiresistan...
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journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/j.resmic.2012.10.017
更新日期：2013-02-01 00:00:00
abstract：:Ferric reductase catalyzes the reduction of ferric iron into ferrous iron and plays an essential role in high-affinity iron acquisition. In this study, we found that the cfl1Δ/Δ (orf19.1263) mutant was not defective in iron acquisition. However, deletion of CFL1 increased cellular iron accumulation by elevating surfac...
journal_title：Research in microbiology
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journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/j.resmic.2010.07.006
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journal_title：Research in microbiology
pub_type： 杂志文章
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journal_title：Research in microbiology
pub_type： 杂志文章
doi：10.1016/j.resmic.2009.03.003
更新日期：2009-04-01 00:00:00
abstract：:During an epidemiologic survey, an unidentified strain of Legionella was isolated from water of a thermal spa in France. The strain (Lyon 8420412) had the cultural and biochemical characteristics typical of the genus Legionella. In direct immunofluorescence tests, the strain reacted weakly with fluorescein-conjugated ...
journal_title：Research in microbiology
pub_type： 杂志文章
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更新日期：1989-10-01 00:00:00
