Expression of glial cell line-derived neurotrophic factor and its mRNA in the nigrostriatal pathway following MPTP treatment.

abstract：:The present study was designed to determine the types of acetylcholine receptors involved in the initiation of epileptic seizures from the zona incerta and surrounding structures by cholinergic stimulation in rats. Unilateral intracerebral microinjection of the mixed muscarinic and nicotinic agonist carbachol (3 micro...

journal_title：Brain research

authors： Cruickshank JW,Brudzynski SM,McLachlan RS

更新日期：1994-04-18 00:00:00

abstract：:The distribution of AMPA-type glutamate receptor (GluR) subunits was studied in the Edinger-Westphal nucleus (EW) of chicks and pigeons. GluR1, GluR2, GluR3 and GluR4 subunits appeared to be present in EW neurons of both species, but interspecific differences were observed in the abundance of the different types of su...

journal_title：Brain research

authors： Toledo CA,Britto LR,Pires RS,Veenman CL,Reiner A

更新日期：2002-08-23 00:00:00

abstract：:Cajal-Retzius (CR) cells of the mammalian neocortex co-express the extracellular matrix protein Reelin and p73, a transcription factor involved in cell death and survival. Most neocortical CR cells derive from the cortical hem, with minor additional sources. We analyzed the distribution of Reelin and p73 immunoreactiv...

journal_title：Brain research

authors： Cabrera-Socorro A,Hernandez-Acosta NC,Gonzalez-Gomez M,Meyer G

更新日期：2007-02-09 00:00:00

abstract：:Acutely (by 48 h), as well as after one month survival, morphine (20 mg/kg) significantly potentiated the extent of noradrenergic degeneration in the forebrain of newborn rats caused by 50 mg/kg of 6-hydroxydopamine (6-OHDA) s.c. This was associated with increased regenerative sprouting in the cerebellum and pons-medu...

journal_title：Brain research

authors： Bardo MT,Schmidt RH,Bhatnagar RK

更新日期：1985-10-01 00:00:00

abstract：:The behavioral and EEG effects of rat and ovine corticotropin releasing factor (r- and o-CRF) were compared. Both peptides were injected intracerebroventricularly into rats through chronically implanted cannulae. At the doses of 0.1 and 1 microgram both peptides activated the EEG and stimulated motor activity. At the ...

journal_title：Brain research

authors： Marrosu F,Mereu G,Fratta W,Carcangiu P,Camarri F,Gessa GL

更新日期：1987-04-07 00:00:00

abstract：:Previous studies in piglets show that opioid-induced pial artery dilation was impaired following fluid percussion brain injury (FPI). This study was designed to determine the role of the newly described opioid nociceptin orphanin FQ (NOC/oFQ) in such impaired dilation to other opioids after FPI. CSF NOC/oFQ concentrat...

journal_title：Brain research

authors： Armstead WM

更新日期：2000-06-30 00:00:00

abstract：:Smoking is considered the leading cause of preventable death in the United States, but studies in animals suggest that nicotine is only weakly reinforcing. The maintenance of a dangerous habit by a weakly reinforcing agent has been the topic of some dispute. Using a two-lever "choice" self-administration procedure dev...

journal_title：Brain research

authors： Manzardo AM,Stein L,Belluzzi JD

更新日期：2002-01-04 00:00:00

abstract：:The purpose of the present study is to characterize the striatum of the lamprey by immunohistochemical and tracing techniques. Cells immunoreactive for GABA and substance P (SP), and positive for acetylcholinesterase, are present in the lamprey striatum. Immunoreactive (ir) fibers were detected by antisera raised agai...

journal_title：Brain research

authors： Pombal MA,El Manira A,Grillner S

更新日期：1997-08-22 00:00:00

abstract：:Temperature dysregulation is well known in generalized convulsive status epilepticus but so far has not been reported in non-convulsive forms. In order to detect possible subtle alterations, we have analyzed the capability to compensate for external cooling in an animal model of limbic status epilepticus. Rats with el...

journal_title：Brain research

authors： Holtkamp M,Schmitt FC,Buchheim K,Meierkord H

更新日期：2007-01-05 00:00:00

abstract：:Extracellular recordings were carried out in the primary visual cortex of behaving monkeys. Neurons were activated by moving a visual stimulus on their receptive fields during periods of steady fixation and by moving their receptive fields (smooth pursuit eye movements) on a motionless visual stimulus. Regarding non-o...

journal_title：Brain research

authors： Galletti C,Squatrito S,Battaglini PP,Maioli MG

更新日期：1983-01-31 00:00:00

abstract：:The organization of neuronal cell bodies in the caudal preoptic area (POA) and rostral anterior hypothalamic area (AH) was studied in Nissl-stained brain sections from adult male and female ferrets. Computer-assisted image-analysis procedures were developed to help estimate the areas of cellular density and the sizes ...

journal_title：Brain research

authors： Tobet SA,Zahniser DJ,Baum MJ

更新日期：1986-02-05 00:00:00

abstract：:The distribution of pituitary adenylate cyclase-activating polypeptide (PACAP) was examined in the tooth pulp. In rat and human tooth pulps, PACAP-immunoreactive (IR) nerve fibers were observed around blood vessels and in the subodontoblastic and odontoblastic layers. The predentine and dentine were devoid of such ner...

journal_title：Brain research

authors： Ichikawa H,Sugimoto T

更新日期：2003-08-08 00:00:00

abstract：:Clusters of carotid body (glomus) cells cultured from a few days to 3 weeks, maintained their morphological characteristics during this period. The resting potential (Em) and input resistance (Ro) did not change for 2 weeks but both declined afterwards. The intracellular pH (pHi) of glomus cells, measured with glass m...

journal_title：Brain research

authors： He SF,Wei JY,Eyzaguirre C

更新日期：1991-05-03 00:00:00

abstract：:The effects of bilateral intracranial injections of the D-1 dopamine receptor antagonist SCH 23390 HCl (0, 0.8, 1.6, 3.2, and 6.4 microgram total bilateral dose) administered into the dorsolateral bed nucleus of the stria terminalis (dlBNST) immediately prior to a 3 h intravenous cocaine self-administration session we...

journal_title：Brain research

authors： Epping-Jordan MP,Markou A,Koob GF

更新日期：1998-02-16 00:00:00

abstract：:Neurite formation in neurones isolated from adult molluscs in culture has been shown to depend on the total content of Ca in the cells, intracellular Ca2+ concentration, intracellular acid-alkaline balance, extracellular pH, and the capacity and composition of buffers. The neurones with a low total Ca content prior to...

journal_title：Brain research

authors： Kostenko MA,Musienko VS,Smolikhina TI

更新日期：1983-10-03 00:00:00

abstract：:The rubrointerposital projection was studied in cats where wheat germ agglutinin-horseradish peroxidase (WGA-HRP) was implanted in various parts of the interposed nuclei. No retrogradely labelled rubral cells were observed following implantations in the posterior interposed nucleus, and only very few such cells were i...

journal_title：Brain research

authors： Walberg F,Dietrichs E

更新日期：1986-11-05 00:00:00

abstract：:Despite significant advancements in the understanding of the pathophysiological mechanisms of subarachnoid hemorrhage (SAH), little is known about the emotional consequences. The primary goal of this study was to describe the locomotor and behavioral patterns in rats following both a single-injection and double-inject...

journal_title：Brain research

authors： Boyko M,Azab AN,Kuts R,Gruenbaum BF,Gruenbaum SE,Melamed I,Brotfain E,Shapira Y,Cesnulis E,Zlotnik A

更新日期：2013-01-23 00:00:00

abstract：:We have investigated the role of NMDA receptors in the rat dorsal horn in mediating neuronal responses to noxious hindlimb ischemia, induced by acute occlusion of the femoral artery, as well as in the hyperalgesia evident when noxious mechanical stimuli were applied to the ischemic limb. Two specific NMDA antagonists,...

journal_title：Brain research

authors： Sher GD,Mitchell D

更新日期：1990-07-02 00:00:00

abstract：:Serotonin transporter (5-HTT) mRNA and 5-HTT sites were measured 3 days after treatment with p-chlorophenylalanine, a tryptophan hydroxylase inhibitor. While 5-HTT mRNA levels decreased (P < 0.001) in the dorsal raphe nucleus, 5-HTT binding sites remained unchanged, suggesting that an acute depletion of 5-HT may induc...

journal_title：Brain research

authors： Yu A,Yang J,Pawlyk AC,Tejani-Butt SM

更新日期：1995-08-07 00:00:00

abstract：:Mapping studies with central drug injections in the hungry rat have identified the perifornical lateral hypothalamus as being uniquely sensitive to the feeding suppressive effects of exogenous dopamine, as well as anorexic drugs which release endogenous catecholamines. In the present study, the hypothalamic dopamine-r...

journal_title：Brain research

authors： Leibowitz SF,Rossakis C

更新日期：1979-08-17 00:00:00

abstract：:Nordihydroguaiaretic acid (NDGA) is a powerful antioxidant and/or lipoxygenase (LOX) inhibitor which is isolated from Larrea tridentate. NDGA has been shown to have neuroprotective effects both in vitro and in vivo experiments. However, little is known regarding NDGA's protective mechanism in ischemia/reperfusion (I/R...

journal_title：Brain research

authors： Liu Y,Wang H,Zhu Y,Chen L,Qu Y,Zhu Y

更新日期：2012-03-22 00:00:00

abstract：:Extracellular levels of acetylcholine (ACh) were measured in the central nucleus of the amygdala using microdialysis in 20-min intervals before, during, and after 1 h feeding in food-deprived rats. The results were compared to the effects of peripheral injections of glucose or 'low' (200 mU) and 'high' (1 U) doses of ...

journal_title：Brain research

authors： Hajnal A,Pothos EN,Lénárd L,Hoebel BG

更新日期：1998-02-23 00:00:00

abstract：:The aim of this study was to evaluate the effects of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in the developing brain. Thirty-seven newborn piglets were divided randomly into four groups: normothermic control (NC, n=9); hypothermic control (HC, n=7); normotherm...

journal_title：Brain research

authors： Park WS,Chang YS,Chung SH,Seo DW,Hong SH,Lee M

更新日期：2001-12-20 00:00:00

abstract：:The effect of excitatory amino acid antagonists on antagonist on neuropeptide Y (NPY) and cholinergic neurons in the striatum of the rat was studied by means of NPY immunocytochemistry, DFP histochemistry for acetylcholinesterase (AChE), and biochemical determinations of choline acetyltransferase (ChAT). Intrastriatal...

journal_title：Brain research

authors： Boegman RJ,Parent A

更新日期：1988-06-14 00:00:00

abstract：:Extracellular recordings were obtained from spontaneously active neurones located in the dorsal motor nucleus of vagus nerve ( DMX ) in slices of the rat brainstem. Oxytocin applied to the bath at concentrations of 10(-7) M or 10(-6) M excited 79% of these cells in a concentration-dependent, reversible manner. The rem...

journal_title：Brain research

authors： Charpak S,Armstrong WE,Mühlethaler M,Dreifuss JJ

更新日期：1984-05-21 00:00:00

abstract：:Transient ischemia increases tyrosine phosphorylation of N-methyl-D-aspartate (NMDA) receptor. Several tyrosine kinases are involved in this process. In this study, effect of ischemia and reperfusion (I/R) on tyrosine phosphorylation of NMDA receptor subunit 2A (NR2A) and the interaction of two tyrosine kinases, Src a...

journal_title：Brain research

authors： Liu Y,Zhang G,Gao C,Hou X

更新日期：2001-08-03 00:00:00

abstract：:Immunohistochemical and neuronal tracing methods were used in cats to determine which type of postganglionic sympathetic neuron is innervated by preganglionic neurons which contain corticotrophin releasing factor-like immunoreactivity (CRF-LI). Preganglionic neurons with CRF-LI have their cell bodies at two restricted...

journal_title：Brain research

authors： Shafton AD,Oldfield BJ,McAllen RM

更新日期：1992-12-25 00:00:00

abstract：:Neurokinins, such as substance P (SP), modulate the reflex regulation of cardiovascular and respiratory function in the CNS, particularly in the nucleus tractus solitarius (NTS). There is considerable evidence of the action of SP in the NTS, but the precise effects have not yet been determined. Voltage-dependent Ca2+ ...

journal_title：Brain research

authors： Endoh T

更新日期：2006-09-19 00:00:00

abstract：:In addition to synaptic remodeling, formation of new neurons is increasingly acknowledged as an important cue for plastic changes in the central nervous system. Whereas all vertebrates retain a moderate neuroproliferative capacity, phylogenetically younger mammals become dramatically impaired in this potential during ...

journal_title：Brain research

authors： Alpár A,Künzle H,Gärtner U,Popkova Y,Bauer U,Grosche J,Reichenbach A,Härtig W

更新日期：2010-05-12 00:00:00

abstract：:Recent studies have demonstrated the neuroprotective properties of the novel imidazoquinoline benzodiazepine receptor partial agonist, PNU-101017, in the gerbil forebrain ischemia model. The compound effectively reduces delayed post-ischemic (5 min bilateral carotid occlusion) hippocampal CA1 neuronal degeneration eve...

journal_title：Brain research

authors： Hall ED,Fleck TJ,Oostveen JA

更新日期：1998-07-06 00:00:00