The dopamine D-1 receptor antagonist SCH 23390 injected into the dorsolateral bed nucleus of the stria terminalis decreased cocaine reinforcement in the rat.

abstract：:Alterations in protein phosphorylation may be important in the pathogenesis of Alzheimer's disease and recent observations suggest that a subset of protein kinase pathways may be selectively altered. Calcium/calmodulin-dependent protein kinase II CaM kinase II) is the most abundant protein kinase in the brain and is b...

journal_title：Brain research

authors： Simonian NA,Elvhage T,Czernik AJ,Greengard P,Hyman BT

更新日期：1994-09-19 00:00:00

abstract：:In sections of rat brain treated for Wisteria floribunda agglutinin (WFA) labelling the occurrence of parvalbumin (PARV)-, calbindin (CALB)- or choline acetyltransferase (ChAT) immunoreactivity was analyzed in the basal forebrain using dual-peroxidase and double-fluorescence methods. Only PARV-immunoreactive (-ir) neu...

journal_title：Brain research

authors： Brauer K,Härtig W,Bigl V,Brückner G

更新日期：1993-12-17 00:00:00

abstract：:Multiple sclerosis patients typically experience increased pain that is relatively insensitive to opiate treatment. The mechanistic basis for this increased nociception is currently poorly understood. In the present study, we utilized the Theiler's murine encephalomyelitis virus (TMEV) model of MS to examine possible ...

journal_title：Brain research

authors： Lynch JL,Alley JF,Wellman L,Beitz AJ

更新日期：2008-01-29 00:00:00

abstract：:Previous results indicate that the dopaminergic system in the anterior medial zona incerta (ZI) exerts a stimulatory effect on LH release. In this report changes in dopamine (DA) turnover in the ZI, preoptic area (POA) and arcuate/median eminence area (ARC/ME) (as assessed by the rate of decline in DA concentration af...

journal_title：Brain research

authors： MacKenzie FJ,James MD,Wilson CA

更新日期：1988-03-15 00:00:00

abstract：:In anaesthetized cats, effects of iontophoretic application of angiotensin II were studied in the nuclei of the tractus solitarius. Specifically, its effects were tested on single respiratory neurones, having rhythmic activity related temporally with the phrenic nerve discharge, and on presumed reflex interneurones, w...

journal_title：Brain research

authors： Sessle BJ,Henry JL

更新日期：1987-03-24 00:00:00

abstract：:Immunohistochemistry for Kv1.2, a subunit of voltage-gated K(+) channels, was performed on the trigeminal ganglion (TG). Immunoreactivity (ir) was detected in half (48%) the TG neurons. These neurons were mostly medium-sized to large (range 137.6-2664.8 microm(2), mean+/-S.D. 892.6+/-413.3 microm(2)). A double immunof...

journal_title：Brain research

authors： Ichikawa H,Sugimoto T

更新日期：2003-06-06 00:00:00

abstract：:Intake of an unconditionally preferred taste stimulus (e.g., saccharin) is reduced by contingent administration of a drug of abuse (e.g., morphine). We examined the influence of insular cortex (IC) lesions on morphine-induced suppression of an olfactory cue and two taste stimuli with different levels of perceived inna...

journal_title：Brain research

authors： Lin JY,Roman C,Reilly S

更新日期：2009-10-06 00:00:00

abstract：:Microarray analysis has been used to understand how gene regulation plays a critical role in neuronal injury, survival and repair following ischemic stroke. To identify the transcriptional regulatory elements responsible for ischemia-induced gene expression, we examined gene expression profiles of rat brains following...

journal_title：Brain research

authors： Pulliam JV,Xu Z,Ford GD,Liu C,Li Y,Stovall KC,Cannon VS,Tewolde T,Moreno CS,Ford BD

更新日期：2013-02-07 00:00:00

abstract：:Using a double-label immunofluorescence method, we analyzed the time course of the appearance of Fos and Jun in the nuclei of supraoptic nucleus (SON) neurons following intraperitoneal injection of hypertonic saline. Fos and Jun immunostaining appeared within 30 min, peaked at 90-120 min, and disappeared 4-5 h later. ...

journal_title：Brain research

authors： Wang K,Guldenaar SE,McCabe JT

更新日期：1997-01-23 00:00:00

abstract：:Tetanic but not low frequency stimulation of the perforant path in rat hippocampal slices results in changes in the metabolism of phosphoinositides and phosphatidic acid. The phosphorylation of other, non-inositol lipids was not affected by the high frequency stimulation. The observed changes in phosphoinositide metab...

journal_title：Brain research

authors： Bär PR,Wiegant F,Lopes da Silva FH,Gispen WH

更新日期：1984-11-12 00:00:00

abstract：:Three to five microliters of 50% HRP in saline was injected along a central axis into one of the 6 extraocular muscles in each of 18 adult pigeons. The brain was fixed and serially sectioned 16-20 h postinjection and the HRP reacted with tetramethylbenzidine (TMB). HRP-labeled proprioceptive neurons were located in th...

journal_title：Brain research

authors： Eden AR,Correia MJ,Steinkuller PG

更新日期：1982-04-08 00:00:00

abstract：:Since it has been proposed that oxidized protein accumulation plays a critical role in brain aging, we have investigated their contents in synaptic mitochondria from five age groups of mice. Protein carbonyl content in synaptic mitochondria showed a significant positive correlation with age (r = 0.95, P = 0.01). A lin...

journal_title：Brain research

authors： Martinez M,Hernández AI,Martínez N,Ferrándiz ML

更新日期：1996-08-26 00:00:00

abstract：:Visual acuity was measured by determining the highest spatial acuity at which chickens aged 1-25 days jumped consistently to a physically supported grating instead of to an unsupported homogeneous field. In contrast to the gradual visual development found for kittens, monkeys, and humans, the chicken exhibits asymptot...

journal_title：Brain research

authors： Over R,Moore D

更新日期：1981-05-04 00:00:00

abstract：:The possibility that central adenosine A1 and A2a receptors mediate opiate dependence was examined in morphine-treated mice using radioligand binding methods. Mice treated with morphine for 72 h demonstrated significant increases in naloxone precipitated abstinence behaviors of jumping, wet-dog shakes, teeth chatterin...

journal_title：Brain research

authors： Kaplan GB,Leite-Morris KA,Sears MT

更新日期：1994-09-19 00:00:00

abstract：:We investigated the effect of adenosine A1 receptors on the release of acetylcholine (ACh) and GABA, and on the intracellular calcium concentration ([Ca2+]i) response in cultured chick amacrine-like neurons, stimulated by KCl depolarization. The KCl-induced release of [3H]ACh, but not the release of [14C]GABA, was pot...

journal_title：Brain research

authors： Santos PF,Caramelo OL,Carvalho AP,Duarte CB

更新日期：2000-01-03 00:00:00

abstract：:Traumatic brain injury (TBI) contributes to morbidity in children, and more boys experience TBI. Cerebral autoregulation is impaired after TBI, contributing to poor outcome. Cerebral Perfusion Pressure (CPP) is often normalized by use of vasoactive agents to increase mean arterial pressure (MAP). In prior studies of n...

journal_title：Brain research

authors： Curvello V,Hekierski H,Pastor P,Vavilala MS,Armstead WM

更新日期：2017-09-01 00:00:00

abstract：:Chronically epileptic male adult rats in the pilocarpine model of temporal lobe epilepsy (TLE), exhibited gross expansion of abdominal fat mass and significant weight gain several months after induction of status epilepticus (SE) when compared to control rats. We hypothesized that epileptogenesis can induce molecular ...

journal_title：Brain research

authors： Ruiz N,Pacheco LF,Farrell B,Cox CB,Ermolinsky BS,Garrido-Sanabria ER,Nair S

更新日期：2011-12-02 00:00:00

abstract：:The regulation of circadian rhythms changes with age. In humans, changes in the timing of sleep and wakefulness are especially common. In Syrian hamsters Mesocricetus auratus the free running period of the activity/rest rhythm shortens with age. The present study tested the hypothesis that critical age-related changes...

journal_title：Brain research

authors： Viswanathan N,Davis FC

更新日期：1995-07-17 00:00:00

abstract：:α4βδ GABA(A) receptors (GABARs) have low CNS expression, but their expression is increased by 48h exposure to the neurosteroid THP (3α-OH-5α[β]-pregnan-20-one). THP also increases the efficacy of δ-containing GABARs acutely, where GABA is a partial agonist. Thus, we examined effects of THP (100 nM) and full GABA agoni...

journal_title：Brain research

authors： Kuver A,Shen H,Smith SS

更新日期：2012-06-29 00:00:00

abstract：:The herpes virus suis has been used as a tracer for the pathways in the central nervous system of the rat. The viruses have been inoculated in various peripheral structures innervated by the trigeminal nerve, namely in the cornea by instillation or scarification, in the anterior chamber of the eye by injection and als...

journal_title：Brain research

authors： Martin X,Dolivo M

更新日期：1983-08-29 00:00:00

abstract：:Previous studies have found that the primary change in the brain of chronic alcoholics is a selective loss of white matter in cerebral hemispheres. It is unknown whether the loss of white matter is due to alcohol-induced degeneration of axons in white matter, and this hypothesis has never been tested. We used a newly ...

journal_title：Brain research

authors： Tang Y,Pakkenberg B,Nyengaard JR

更新日期：2004-12-17 00:00:00

abstract：:Magnetoencephalography (MEG) was used to investigate the response to speech sounds that differ in onset dynamics, parameterized as words that have initial stop consonants (e.g., /b/, /t/) or do not (e.g., /m/, /f/). Latency and amplitude of the M100 auditory evoked neuromagnetic field, recorded over right and left aud...

journal_title：Brain research

authors： Gage N,Poeppel D,Roberts TP,Hickok G

更新日期：1998-12-14 00:00:00

abstract：:A classification of the parietal corticofugal neurons was performed in cats under Nembutal anesthesia. Eighty-eight neurons were identified with antidromic activation by the pontine stimulation. Thirteen neurons were furthermore identified with intracellular HRP staining. In these neurons, we found the close correlati...

journal_title：Brain research

authors： Samejima A,Yamamoto T,Ito J,Oka H

更新日期：1985-11-11 00:00:00

abstract：:[1-14C]Octanoate (OCTO) is rapidly extracted from blood and metabolized by brain. Up to 6 min following an intravenous pulse injection the autoradiographic pattern of brain labeling reflects differences in blood flow and energy metabolism. When animals are given OCTO during visual or somatosensory stimulation the auto...

journal_title：Brain research

authors： Rowley H,Collins RC

更新日期：1985-06-03 00:00:00

abstract：:In this report, using a push-pull perfusion technique, we examined in vivo the effects of exogenous dopamine (DA) on the output of neurochemical substances from the caudate nucleus (CN) of freely behaving rats. Exogenous DA, at concentrations of 10(-5) M, 5 x 10(-5) M and 10(-4) M, in modified Krebs-Ringer phosphate m...

journal_title：Brain research

authors： Chang GD,Ramirez VD

更新日期：1989-03-06 00:00:00

abstract：:Ouabain binds to the catalytic subunit of Na+,K+-ATPase and specific [3H]ouabain binding can be used as a measure of the number of active enzyme molecules present in a given tissue. Specific [3H]ouabain binding can be demonstrated in frozen, cryostat sections from rat brain and pineal and these sites have the characte...

journal_title：Brain research

authors： Caspers ML,Schwartz RD,Labarca R,Paul SM

更新日期：1987-04-21 00:00:00

abstract：:This paper reports studies on the biotransformation of the nonapeptide arginine-vasotocin (AVT) by both rat and chicken brain synaptic membranes. The fragments which were formed during digestion of AVT1-9, were isolated by high pressure liquid chromatography (HPLC) and chemically characterized by amino acid compositio...

journal_title：Brain research

authors： Wang XC,Burbach JP,Verhoef JC,De Wied D

更新日期：1983-09-19 00:00:00

abstract：:A reduction in adenosine deaminase acting on RNA 2 (ADAR2) activity causes the death of spinal motor neurons specifically via the GluA2 Q/R site-RNA editing failure in sporadic amyotrophic lateral sclerosis (ALS). We studied, over time, the spinal cords of ADAR2-knockout mice, which are the mechanistic model mice for ...

journal_title：Brain research

authors： Sasaki S,Takenari Yamashita,Hideyama T,Kwak S

更新日期：2014-03-06 00:00:00

abstract：:Obesity and related metabolic disorders are important side effects of some antipsychotic drugs (APs). The currently available animal model of AP-induced bodyweight gain (BWG) in rats is based on administration of sulpiride (SUL). However, this model has important limitations. For example, SUL is a pure dopamine antago...

journal_title：Brain research

authors： Baptista T,Araujo de Baptista E,Ying Kin NM,Beaulieu S,Walker D,Joober R,Lalonde J,Richard D

更新日期：2002-12-06 00:00:00

abstract：:Small injections of the lectin Phaseolus vulgaris-leucoagglutinin (PHA-L) in the external segment of the pallidum (GPe) in the squirrel monkey (Saimiri sciureus) and in the rhesus monkey (Macaca mulatta) led to anterograde labeling of fibers in the internal segment of the pallidum (GPi). These fibers formed numerous l...

journal_title：Brain research

authors： Hazrati LN,Parent A,Mitchell S,Haber SN

更新日期：1990-11-12 00:00:00