Abstract:
UNLABELLED:This report presents findings of a community survey of 3,021 adolescents and young adults aged 14-24 years in Munich, Germany, carried out to determine the prevalence of use and abuse of and dependence on ecstasy, amphetamines and hallucinogens. The response rate was 71%. RESULTS:(1) In 1995, 4% of the male and 2.3% of the female respondents aged 14-24 reported the use of ecstasy. Ecstasy-related substances (amphetamines and chemically related substances) were reported by 3.6% of men and 1.6% of women. Hallucinogens were reported slightly less frequently by 3% of men and about 2% of women (LSD combined with others). (2) Compared to findings from a 1990 survey this constitutes a substantial, at least twofold, increase in consumption rate of both types of substances. (3) Among lifetime users of both ecstasy and related substances as well as hallucinogens about two thirds could be regarded as regular users. (4) The prevalence of DSM-IV abuse and dependence on ecstasy and related substances is about 1%, identical to rates of hallucinogen abuse and dependence. Findings also point to a significant dependence potential for both substances. (5) Furthermore, considerable overlap between the two substances was found. CONCLUSION:Our study suggests a substantial increase in both the use of ecstasy and related substances as well as hallucinogens. The data further suggest that the increase is strongest in younger age groups, but the risk of first use of these substances continues to be present up to the age of 24 years. The higher proportion of women contributing to this increase is noteworthy.
journal_name
Eur Addict Resjournal_title
European addiction researchauthors
Schuster P,Lieb R,Lamertz C,Wittchen HUdoi
10.1159/000018925subject
Has Abstractpub_date
1998-03-01 00:00:00pages
75-82issue
1-2eissn
1022-6877issn
1421-9891pii
ear04075journal_volume
4pub_type
杂志文章abstract:AIM:The aim of this study was to evaluate the role of the glutamate receptor subunit-7 (GluR7, GRIK 3) rs6691840 (Ser310Ala, T928G) in the pathogenesis of alcohol dependence (AD). METHODS:DNA was provided from AD patients (n = 209) and healthy control subjects (n = 308) all of Polish descent. The history of alcoholism...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000341714
更新日期:2013-01-01 00:00:00
abstract::In Spain, detoxification in general hospitals plays an important role in the medical care of patients. We aim to provide clinicians with information on the prevalence and correlates of psychiatric co-morbidity in drug abusers in detoxification. A sample of 115 substance-abuse inpatients (mean age 31.9 +/- 6.4 years) i...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000104881
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Alcohol consumption is one of the most important factors for disease and disability in Europe. In clinical trials, nalmefene has resulted in a significant reduction in the number of heavy-drinking days (HDDs) per month and total alcohol consumption (TAC) among alcohol-dependent patients versus placebo. METH...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000362408
更新日期:2014-01-01 00:00:00
abstract:AIMS:The issue of leptin as a putative state marker of alcohol use and its role in craving has been raised in the last few years. Recently, a strong GABA-ergic modulation of leptin was postulated. The aim of the pilot study was to examine leptin levels in correlation with the strongly GABA-mimetic active substance clom...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000331017
更新日期:2012-01-01 00:00:00
abstract::There is a long-recognized association between alcohol consumption and aggressive behavior. This study was designed to examine aggression in a group of socially well-adapted recovered alcoholics (RA). The question addressed was whether the treatment, together with long-term abstinence from alcohol, could reduce aggres...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000097938
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND/AIMS:Methylphenidate (MPH) has been the most commonly used intravenous (i.v.) substance in Iceland in recent years. In Iceland, MPH is available in 3 forms: immediate-release (IR) tablets (MPH IR, short-acting), sustainable-release (SR) capsules (MPH SR, long-acting) and osmotic-release (OROS) tablets (MPH O...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000446428
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Behavioral problems in adolescence have been shown to be associated with the presence of a positive family history of alcoholism (FH+), obstetric complications (OCs), and negative parenting practices. METHOD:This study tested the relation of these factors to aggression/delinquency and attention problems in ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000073721
更新日期:2004-01-01 00:00:00
abstract::The aim of this study was to investigate to what extent alcohol-specific parenting practices relate to adolescents' alcohol use, binge drinking, and alcohol-related problems, and whether these associations are moderated by socioeconomic status (SES), i.e. parents' education level and family income. The present data we...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000110408
更新日期:2008-01-01 00:00:00
abstract::Alcohol and illicit drug use has a significant impact on global health. Alcohol consumption is increasing worldwide, particularly in developing countries and countries in transition, leading to an increasing number of health and social problems, both acute and chronic. Illicit drug use is also increasing, particularly...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000050727
更新日期:2001-08-01 00:00:00
abstract::We tested the use of some subscales of the psychiatric symptom checklist SCL-90-R in predicting relapse within a 1-year follow-up period after a combined detoxification- and abstinence-focused day patient psychotherapy program in 20 men and 13 women with alcohol dependence. Scores of the SCL-90-R subscales interperson...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000066131
更新日期:2002-11-01 00:00:00
abstract::In France, during the 1990s, there have been some rapid developments in the treatment of opioid addiction with the introduction of legal substitution agents. Originally, some patients were treated with morphine sulfate, but this was superseded by high dose buprenorphine (Subutex(R)) and methadone. This resulted in tho...
journal_title:European addiction research
pub_type: 临床试验,杂志文章
doi:10.1159/000052035
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Tobacco product warning labels are a key health communication medium with plain packaging noted as the next step in the evolution of tobacco packaging. We assessed the self-reported impact of text versus pictorial health warnings and the determinants of support for plain packaging of tobacco products in the ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000366019
更新日期:2015-01-01 00:00:00
abstract::γ-Butyrolactone (GBL) is a popular drug of abuse which is easily available over the internet. Following a UK classification change to a class C drug in January 2010, internet supply has become difficult. Some of the effects have resulted in sourcing GBL from industrial solvents. We report a case of a 24-year-old man w...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000324343
更新日期:2011-01-01 00:00:00
abstract::In the article the growing interest of studies on treatment systems rather than specific treatment modalities is taken as a starting point for a discussion and outlook on how the research agenda of drug treatment research will develop in the near future. The relative absence of research that provides substantial guida...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018984
更新日期:1999-09-01 00:00:00
abstract:BACKGROUND:Two forms of institutionalized pressure to treatment can be distinguished in Switzerland: civil commitment and court referral. In court referral, the referred patient has the right to refuse treatment. OBJECTIVES:To compare court referrals for inpatient treatment to voluntary therapy. METHODS:Comparison of...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000052058
更新日期:2002-04-01 00:00:00
abstract:AIMS:To explore previously unreported rates and trends in opioid-related mortality in Israel, 2005-2014. METHODS:Data was obtained from the national database on causes of death. Drug poisoning deaths were divided into opioid-related deaths and deaths related to other drugs according to International Classification of ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000485033
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:There is a high prevalence of smoking among heavy drinkers, which is often forgotten even though it has important health consequences. AIM:To evaluate the effects that providing an intensive tobacco cessation treatment simultaneously with alcohol dependence treatment versus delayed treatment (first alcoho...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000321256
更新日期:2011-01-01 00:00:00
abstract::The primary source for evaluating treatment outcome in alcoholism is usually verbal self-report. Because the validity of self-report is often doubted, more objective markers for treatment outcome are needed. In this study, we compared self-report data from 238 male alcohol-dependent patients participating in a combine...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018972
更新日期:1999-06-01 00:00:00
abstract:BACKGROUND:Methadone maintenance treatment (MMT) has been shown to dramatically reduce illicit opioid use and criminal activity among injection drug users (IDU). However, questions remain concerning the effect of MMT in reducing rates of incarceration among IDU. We therefore sought to investigate the long-term effect o...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000130418
更新日期:2008-01-01 00:00:00
abstract::In this paper, the effectiveness of the treatment program developed by Proyecto Hombre ('Project Mankind') in Asturias, Spain, is evaluated. In a long-term follow-up (range from 73 days to 8 years) with a sample of 249 subjects, the results obtained by subjects completing the treatment (194) were compared with pre-tre...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000049484
更新日期:2002-01-01 00:00:00
abstract:AIMS:To investigate the gender differences in the patterns of cannabis use (CU), namely frequency, times of day, social context and methods and in their association with DSM-IV cannabis dependence. METHODS:A sample of 3,904 students from German universities was recruited via an internet survey. Logistic regressions an...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000333338
更新日期:2011-01-01 00:00:00
abstract::The objectives of the community-based Early Developmental Stages of Psychopathology (EDSP) Study are described along with a detailed account of the overall design, special design features, sample characteristics and instruments used. The EDSP employed a prospective-longitudinal design to study substance use and other ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000052043
更新日期:2000-12-01 00:00:00
abstract::Depression is a common co-morbid disorder in substance use disorder (SUD) patients. Hence, valid instruments are needed to screen for depression in this subpopulation. In this study, the predictive validity of the Depression, Anxiety and Stress Scale (DASS-21) for the presence of a depressive disorder was investigated...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000485182
更新日期:2017-01-01 00:00:00
abstract:AIMS:There is a scarcity of clinical trials on psychological treatments for concurrent borderline personality disorder (BPD) and substance use disorder (SUD). Mentalization-based treatment (MBT) have shown efficacy in several trials on BPD. The aim of the present study was to examine the feasibility and effectiveness o...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000485564
更新日期:2018-01-01 00:00:00
abstract::A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism. To test this hypothesis, we examined a group of recently detoxified alcoholics with high (n = 25) and low genetic loading for ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000019011
更新日期:2000-06-01 00:00:00
abstract:AIMS:To describe and assess trends in the use of hallucinogens and other adjunct drugs over a 5-year period. DESIGN:Repeated-measures cross-sectional survey. SETTING AND PARTICIPANTS:Annual magazine-based survey targeting people who use drugs in dance contexts. MEASUREMENTS:Lifetime use prevalence (ever used); age o...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000095816
更新日期:2007-01-01 00:00:00
abstract::The current study examined the independent effects of parents' educational attainment and occupational status on adolescent smoking and mediation of smoking-specific communication and parents' smoking behaviours on this link. Data were collected in a multi-informant, full-family design in two sampling waves separated ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000321258
更新日期:2011-01-01 00:00:00
abstract::Data were collected on 1,074 opiate detoxifications conducted with lofexidine, from 40 drug dependency units in the United Kingdom. 671 patients (62.5%) attempted a detoxification in the community, with the remainder attempting an inpatient detoxification. Patients completing the detoxification started on a mean dose ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018962
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:Evaluation of the Addiction Severity Index (ASI) as a screen for identifying sexual and physical assault histories. METHOD:The sensitivity and specificity of the ASI assault items were examined in 146 alcoholic patients with the assault questions of the Composite International Diagnostic Interview posttrauma...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000050740
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:It has been determined that cannabis has adverse effects on brain tissue, and that increased S100 calcium binding protein B (S100B) blood levels are markers of neuronal damage. Therefore, the aim of this study was to evaluate the S100B levels in cannabis use disorder. METHOD:Thirty-two patients with cannabi...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000442046
更新日期:2016-01-01 00:00:00