Abstract:
:The objectives of the community-based Early Developmental Stages of Psychopathology (EDSP) Study are described along with a detailed account of the overall design, special design features, sample characteristics and instruments used. The EDSP employed a prospective-longitudinal design to study substance use and other mental disorders in a representative population sample of 3,021 subjects aged 14-24 years (birth cohorts 1970-1981) at 'baseline' - the outset of the study. Two follow-up investigations were conducted after the baseline investigation covering an overall period of 3-4 years. Special design features are the linkage with a family supplement (EDSP-FS) as well as neurobiological laboratory studies of high-risk subjects.
journal_name
Eur Addict Resjournal_title
European addiction researchauthors
Lieb R,Isensee B,von Sydow K,Wittchen HUdoi
10.1159/000052043keywords:
subject
Has Abstractpub_date
2000-12-01 00:00:00pages
170-82issue
4eissn
1022-6877issn
1421-9891pii
52043journal_volume
6pub_type
杂志文章abstract::We tested the use of some subscales of the psychiatric symptom checklist SCL-90-R in predicting relapse within a 1-year follow-up period after a combined detoxification- and abstinence-focused day patient psychotherapy program in 20 men and 13 women with alcohol dependence. Scores of the SCL-90-R subscales interperson...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000066131
更新日期:2002-11-01 00:00:00
abstract:AIM:The aim of this study was to evaluate the role of the glutamate receptor subunit-7 (GluR7, GRIK 3) rs6691840 (Ser310Ala, T928G) in the pathogenesis of alcohol dependence (AD). METHODS:DNA was provided from AD patients (n = 209) and healthy control subjects (n = 308) all of Polish descent. The history of alcoholism...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000341714
更新日期:2013-01-01 00:00:00
abstract::A number of studies point at platelet monoamine oxidase (MAO) activity being reduced in alcoholics with a family history of drinking, this being a possible vulnerability marker for alcoholism. To test this hypothesis, we examined a group of recently detoxified alcoholics with high (n = 25) and low genetic loading for ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000019011
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Behavioral problems in adolescence have been shown to be associated with the presence of a positive family history of alcoholism (FH+), obstetric complications (OCs), and negative parenting practices. METHOD:This study tested the relation of these factors to aggression/delinquency and attention problems in ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000073721
更新日期:2004-01-01 00:00:00
abstract::The aim of this study was to evaluate the change of psychological distress measured by the symptom checklist in alcohol dependent inpatients during treatment and at follow-up. In addition, psychological distress as a predictive variable for abstinence or relapse during a 1-year follow-up was investigated. In a sample ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000090424
更新日期:2006-01-01 00:00:00
abstract:AIMS:To describe and assess trends in the use of hallucinogens and other adjunct drugs over a 5-year period. DESIGN:Repeated-measures cross-sectional survey. SETTING AND PARTICIPANTS:Annual magazine-based survey targeting people who use drugs in dance contexts. MEASUREMENTS:Lifetime use prevalence (ever used); age o...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000095816
更新日期:2007-01-01 00:00:00
abstract:AIMS:The issue of leptin as a putative state marker of alcohol use and its role in craving has been raised in the last few years. Recently, a strong GABA-ergic modulation of leptin was postulated. The aim of the pilot study was to examine leptin levels in correlation with the strongly GABA-mimetic active substance clom...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000331017
更新日期:2012-01-01 00:00:00
abstract:AIMS:To investigate the gender differences in the patterns of cannabis use (CU), namely frequency, times of day, social context and methods and in their association with DSM-IV cannabis dependence. METHODS:A sample of 3,904 students from German universities was recruited via an internet survey. Logistic regressions an...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000333338
更新日期:2011-01-01 00:00:00
abstract::There is a long-recognized association between alcohol consumption and aggressive behavior. This study was designed to examine aggression in a group of socially well-adapted recovered alcoholics (RA). The question addressed was whether the treatment, together with long-term abstinence from alcohol, could reduce aggres...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000097938
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:In 2003, Denmark lowered its tax on spirits, and in 2004, Sweden increased its traveller import quotas. AIM:The aim of the study was to determine whether these two changes increased self-reported alcohol consumption in southern Sweden, which is located near Denmark. METHOD:Data were collected through telep...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000314358
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:There is increasing interest in naltrexone, an opiate antagonist, in the treatment of opiate addicts. The effects of naltrexone are often compromised by a lack of compliance and drop-out. The effects of this compound are probably more favorable when combined with a psychosocial intervention such as the Commu...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000068808
更新日期:2003-04-01 00:00:00
abstract::In a cross-sectional multicentre study, we compared the characteristics of heroin chasers and heroin injectors. Subjects were 162 primarily opioid-dependent volunteers for whom either chasing (n = 85) or injecting (n = 77) was the principal route of heroin administration. Each subject was rated by means of the Swiss v...
journal_title:European addiction research
pub_type: 杂志文章,多中心研究
doi:10.1159/000019019
更新日期:2000-09-01 00:00:00
abstract:BACKGROUND:Alcohol consumption is one of the most important factors for disease and disability in Europe. In clinical trials, nalmefene has resulted in a significant reduction in the number of heavy-drinking days (HDDs) per month and total alcohol consumption (TAC) among alcohol-dependent patients versus placebo. METH...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000362408
更新日期:2014-01-01 00:00:00
abstract::γ-Butyrolactone (GBL) is a popular drug of abuse which is easily available over the internet. Following a UK classification change to a class C drug in January 2010, internet supply has become difficult. Some of the effects have resulted in sourcing GBL from industrial solvents. We report a case of a 24-year-old man w...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000324343
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To investigate drug use among secondary schoolchildren aged 14-18 years in the city of Szeged in Hungary in order to observe and describe drug use, smoking and alcohol intake and to find risk factors for these behaviours. METHODS:The questionnaire was concerned with recreational drug use, smoking and drinkin...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000081415
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND/AIMS:In recent years, quality of life (QoL) assessments have proved useful for evaluating and comparing drug treatment programs. To compare QoL of patients maintained on methadone versus slow-release morphine, a prospective, randomized, double-blind, double-dummy, cross-over study was conducted. METHODS:Ove...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000113724
更新日期:2008-01-01 00:00:00
abstract:AIMS:To analyse correlates of anabolic androgenic steroids (AAS) use in the general male population. DESIGN:A national household survey. PARTICIPANTS:Individuals aged 15-64 years in Sweden. MEASUREMENTS:AAS use and potential correlates of AAS use, including demographic data, financial situation, physical training, a...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000333037
更新日期:2012-01-01 00:00:00
abstract:AIMS:The aim of this paper is to illustrate how Switzerland was able to play such a pioneering role in the field of addiction treatment, in creating a drug policy that includes the medical prescription of diacetylmorphine (heroin). The paper will also describe the role of knowledge brokering processes and coalition bui...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000357234
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Tobacco product warning labels are a key health communication medium with plain packaging noted as the next step in the evolution of tobacco packaging. We assessed the self-reported impact of text versus pictorial health warnings and the determinants of support for plain packaging of tobacco products in the ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000366019
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:The study presents data about age of onset of alcohol, cigarette and cannabis use and investigates the association between age of onset and later drug use patterns. METHODS:Using a sample from a cross-sectional multi-site study, personal interviews were conducted with 3,503 individuals aged 12-49 years. Las...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000083038
更新日期:2005-01-01 00:00:00
abstract::The programme of prescribing amphetamines and opiates to drug users in Stockholm carried out from 1965 to 1967 has frequently been referred to in the European drug policy debate. In this article, originally presented at the Conference on Drug Use and Drug Policy in Amsterdam in September 1996, the programme is describ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018951
更新日期:1998-12-01 00:00:00
abstract::In Spain, detoxification in general hospitals plays an important role in the medical care of patients. We aim to provide clinicians with information on the prevalence and correlates of psychiatric co-morbidity in drug abusers in detoxification. A sample of 115 substance-abuse inpatients (mean age 31.9 +/- 6.4 years) i...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000104881
更新日期:2007-01-01 00:00:00
abstract:UNLABELLED:This report presents findings of a community survey of 3,021 adolescents and young adults aged 14-24 years in Munich, Germany, carried out to determine the prevalence of use and abuse of and dependence on ecstasy, amphetamines and hallucinogens. The response rate was 71%. RESULTS:(1) In 1995, 4% of the male...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018925
更新日期:1998-03-01 00:00:00
abstract::Adult attention deficit/hyperactivity disorder (ADHD) often co-occurs with substance use disorders (SUD) and is associated with early onset and more severe development of SUD and with reduced treatment effectiveness. Screening tools allow for a good recognition of possible ADHD in adults with SUD and should be used ro...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000487767
更新日期:2018-01-01 00:00:00
abstract::Depression is a common co-morbid disorder in substance use disorder (SUD) patients. Hence, valid instruments are needed to screen for depression in this subpopulation. In this study, the predictive validity of the Depression, Anxiety and Stress Scale (DASS-21) for the presence of a depressive disorder was investigated...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000485182
更新日期:2017-01-01 00:00:00
abstract::Engaging in online games has become increasingly important as a part of leisure activity in adolescents and adults. While the majority of people use these games in a healthy way, epidemiological studies show that some develop excessive use and symptoms that are related to those of substance-related addictions. Despite...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000355832
更新日期:2014-01-01 00:00:00
abstract:AIMS:Qualitative studies find that men and women in Russia have different preferences for alcoholic beverages, but quantitative evidence for gender differences in beverage type choice remains scarce. The purpose of this article is to test numerically whether and to what extent men and women in Russia differ in terms of...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000342313
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND/AIMS:Methylphenidate (MPH) has been the most commonly used intravenous (i.v.) substance in Iceland in recent years. In Iceland, MPH is available in 3 forms: immediate-release (IR) tablets (MPH IR, short-acting), sustainable-release (SR) capsules (MPH SR, long-acting) and osmotic-release (OROS) tablets (MPH O...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000446428
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:Besides numerous advantages and commodities offered by smartphones, there are obvious unhealthy effects. The global trend of an increase in the frequency of usage of smartphones, that is, prolonged screen time, is closely related to problematic smartphone use. The aim of our study was to measure the level of...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000506738
更新日期:2021-01-01 00:00:00
abstract::This longitudinal study of 600 families concentrates on the influence of parental anti-smoking socialization by examining both (a) the effects of eight indicators of anti-smoking socialization on adolescent smoking and (b) the influence of parental smoking on the effectiveness of their anti-smoking socialization. Robu...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000088580
更新日期:2006-01-01 00:00:00