Abstract:
:We tested the use of some subscales of the psychiatric symptom checklist SCL-90-R in predicting relapse within a 1-year follow-up period after a combined detoxification- and abstinence-focused day patient psychotherapy program in 20 men and 13 women with alcohol dependence. Scores of the SCL-90-R subscales interpersonal sensitivity (p = 0.008), anxiety (p = 0.022), phobic anxiety (p = 0.019) and Global Severity Index (GSI; p = 0.040) on admission were higher in the subgroup with relapse within the first year after therapy. A decrease in depression (p = 0.004), anxiety (p = 0.006) and GSI (p = 0.006) scores during therapy was associated with a longer abstinence duration (shorter vs. longer than 24 weeks). Therefore we propose to further investigate the capacity of the SCL-90-R to identify subgroups at higher risk for relapse after detoxification and abstinence therapy in patients with alcohol dependence.
journal_name
Eur Addict Resjournal_title
European addiction researchauthors
Lucht M,Jahn U,Barnow S,Freyberger HJdoi
10.1159/000066131keywords:
subject
Has Abstractpub_date
2002-11-01 00:00:00pages
190-4issue
4eissn
1022-6877issn
1421-9891pii
66131journal_volume
8pub_type
杂志文章abstract:AIM:The aim of this study was to evaluate the role of the glutamate receptor subunit-7 (GluR7, GRIK 3) rs6691840 (Ser310Ala, T928G) in the pathogenesis of alcohol dependence (AD). METHODS:DNA was provided from AD patients (n = 209) and healthy control subjects (n = 308) all of Polish descent. The history of alcoholism...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000341714
更新日期:2013-01-01 00:00:00
abstract:AIMS:Qualitative studies find that men and women in Russia have different preferences for alcoholic beverages, but quantitative evidence for gender differences in beverage type choice remains scarce. The purpose of this article is to test numerically whether and to what extent men and women in Russia differ in terms of...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000342313
更新日期:2013-01-01 00:00:00
abstract::The programme of prescribing amphetamines and opiates to drug users in Stockholm carried out from 1965 to 1967 has frequently been referred to in the European drug policy debate. In this article, originally presented at the Conference on Drug Use and Drug Policy in Amsterdam in September 1996, the programme is describ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018951
更新日期:1998-12-01 00:00:00
abstract:AIMS:To explore previously unreported rates and trends in opioid-related mortality in Israel, 2005-2014. METHODS:Data was obtained from the national database on causes of death. Drug poisoning deaths were divided into opioid-related deaths and deaths related to other drugs according to International Classification of ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000485033
更新日期:2017-01-01 00:00:00
abstract::The current study examined the independent effects of parents' educational attainment and occupational status on adolescent smoking and mediation of smoking-specific communication and parents' smoking behaviours on this link. Data were collected in a multi-informant, full-family design in two sampling waves separated ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000321258
更新日期:2011-01-01 00:00:00
abstract::The aim of this study was to evaluate the change of psychological distress measured by the symptom checklist in alcohol dependent inpatients during treatment and at follow-up. In addition, psychological distress as a predictive variable for abstinence or relapse during a 1-year follow-up was investigated. In a sample ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000090424
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:The study presents data about age of onset of alcohol, cigarette and cannabis use and investigates the association between age of onset and later drug use patterns. METHODS:Using a sample from a cross-sectional multi-site study, personal interviews were conducted with 3,503 individuals aged 12-49 years. Las...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000083038
更新日期:2005-01-01 00:00:00
abstract::In Spain, detoxification in general hospitals plays an important role in the medical care of patients. We aim to provide clinicians with information on the prevalence and correlates of psychiatric co-morbidity in drug abusers in detoxification. A sample of 115 substance-abuse inpatients (mean age 31.9 +/- 6.4 years) i...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000104881
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:Alcohol consumption is one of the most important factors for disease and disability in Europe. In clinical trials, nalmefene has resulted in a significant reduction in the number of heavy-drinking days (HDDs) per month and total alcohol consumption (TAC) among alcohol-dependent patients versus placebo. METH...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000362408
更新日期:2014-01-01 00:00:00
abstract::Data were collected on 1,074 opiate detoxifications conducted with lofexidine, from 40 drug dependency units in the United Kingdom. 671 patients (62.5%) attempted a detoxification in the community, with the remainder attempting an inpatient detoxification. Patients completing the detoxification started on a mean dose ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000018962
更新日期:1999-03-01 00:00:00
abstract:BACKGROUND:Alcohol use among medical specialists remains a delicate topic. However, the number of prevalence studies remains very limited in Western European countries. AIMS:To explore alcohol use and hazardous drinking among male and female medical specialists. METHODS:All medical specialists in Belgium--a typical W...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000341993
更新日期:2013-01-01 00:00:00
abstract::γ-Butyrolactone (GBL) is a popular drug of abuse which is easily available over the internet. Following a UK classification change to a class C drug in January 2010, internet supply has become difficult. Some of the effects have resulted in sourcing GBL from industrial solvents. We report a case of a 24-year-old man w...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000324343
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND/AIMS:In recent years, quality of life (QoL) assessments have proved useful for evaluating and comparing drug treatment programs. To compare QoL of patients maintained on methadone versus slow-release morphine, a prospective, randomized, double-blind, double-dummy, cross-over study was conducted. METHODS:Ove...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000113724
更新日期:2008-01-01 00:00:00
abstract:AIM:The purpose of this study was to investigate the role of serotonergic genes in the development of alcohol dependence. The manifestation of alcohol withdrawal symptoms related to serotonergic polymorphisms in alcoholics was also examined. METHODS:The role of polymorphisms in the serotonin receptor 1A (5-HT1A), sero...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000173008
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVE:To assess smoking habit and awareness of smoking as a potential cause of disease among relatives of patients with serious smoking-related disorders. DESIGN AND SETTING:A survey using a face-to-face interview-assisted questionnaire at the Ege University Hospital between October 1998 and March 1999. SUBJECTS:...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000059380
更新日期:2002-06-01 00:00:00
abstract::Engaging in online games has become increasingly important as a part of leisure activity in adolescents and adults. While the majority of people use these games in a healthy way, epidemiological studies show that some develop excessive use and symptoms that are related to those of substance-related addictions. Despite...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000355832
更新日期:2014-01-01 00:00:00
abstract::This study investigates whether antismoking peer pressure and/or nonsmoking peers are protective factors and decrease young adults' likelihood to smoke. An experiment was conducted among 59 daily-smoking young adults aged 16-24 years. The experiment consisted of four conditions. During the session, the confederate and...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000330318
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:In France, most patients with opioid use disorder (OUD) have been treated by buprenorphine, prescribed by general practitioners (GP) in private practice since 1996. This has contributed to building a 'French model' facilitating access to treatment based on the involvement of GPs in buprenorphine prescription...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000506630
更新日期:2020-01-01 00:00:00
abstract:UNLABELLED:This study evaluated automated techniques including personalized normative feedback and protective behavioral strategies, for brief interventions intended to reduce peak alcohol concentrations in university students. After completing baseline assessment, a total of 1,678 hazardous-drinking consumers were ran...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000381017
更新日期:2015-01-01 00:00:00
abstract::Both heroin abuse and early life stress (ELS) affect the immune system and the hypothalamic-pituitary-adrenal (HPA) axis. Additionally, accelerated aging due to mild inflammation has been indicated in these conditions. The present study aims to compare plasma levels of apoptosis markers, inflammatory markers, and stre...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000503880
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:Evaluation of the Addiction Severity Index (ASI) as a screen for identifying sexual and physical assault histories. METHOD:The sensitivity and specificity of the ASI assault items were examined in 146 alcoholic patients with the assault questions of the Composite International Diagnostic Interview posttrauma...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000050740
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND/AIM:Heroin dependence is a chronic relapsing disorder characterized by the compulsion to seek and use heroin. Stress and craving are seen as key factors for heroin use. Moreover, altered hypothalamic-pituitary-adrenal (HPA) axis function has been frequently reported. However, the acute effects of diacetylmor...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000334411
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND/AIMS:Methylphenidate (MPH) has been the most commonly used intravenous (i.v.) substance in Iceland in recent years. In Iceland, MPH is available in 3 forms: immediate-release (IR) tablets (MPH IR, short-acting), sustainable-release (SR) capsules (MPH SR, long-acting) and osmotic-release (OROS) tablets (MPH O...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000446428
更新日期:2016-01-01 00:00:00
abstract::In this paper, the effectiveness of the treatment program developed by Proyecto Hombre ('Project Mankind') in Asturias, Spain, is evaluated. In a long-term follow-up (range from 73 days to 8 years) with a sample of 249 subjects, the results obtained by subjects completing the treatment (194) were compared with pre-tre...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000049484
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:A pre-post pilot study was conducted to test the feasibility, acceptability, and potential effectiveness of a fully automatized computer-based intervention targeting hazardous drinking and depressiveness in proactively recruited health care patients (HCPs). To address the importance of the sample selection w...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000499040
更新日期:2019-01-01 00:00:00
abstract:AIMS:There is a scarcity of clinical trials on psychological treatments for concurrent borderline personality disorder (BPD) and substance use disorder (SUD). Mentalization-based treatment (MBT) have shown efficacy in several trials on BPD. The aim of the present study was to examine the feasibility and effectiveness o...
journal_title:European addiction research
pub_type: 杂志文章,随机对照试验
doi:10.1159/000485564
更新日期:2018-01-01 00:00:00
abstract::In the UK, few doctors prescribe diamorphine for the treatment of opiate dependence to a small number of patients. A retrospective case note review of patients receiving diamorphine in 2000 was conducted in the UK to determine how and why these patients came to receive a prescription for diamorphine. Patient eligibili...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000101550
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND/AIMS:We investigated the psychometric properties of a German translation of the 12-item Autonomy over Tobacco Scale (AUTOS) among 1,195 eighth-grade students. METHODS:Data for this study were collected as part of the fourth wave of data collection of the Smokefree Class Competition intervention in the Saxon...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000334410
更新日期:2012-01-01 00:00:00
abstract::In Europe, adolescent substance misuse increased during the 1990s. Ireland has among the highest rates of substance misuse among schoolchildren in Europe. We sought to describe the socio-demographic and drug misuse profile of children presenting to addiction treatment services in Dublin during the 1990s. Of the 9,874 ...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000076116
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:Buprenorphine has already been registered in 27 European countries for maintenance therapy in opioid-dependent patients. In our office-based prescription study we applied sublingual buprenorphine, initiating the treatment at the addiction clinic with subsequent treatment at the offices of general practitio...
journal_title:European addiction research
pub_type: 杂志文章
doi:10.1159/000077698
更新日期:2004-01-01 00:00:00